医師・医学生の皆さまへ 業績集

2017

Hazeki N, Tachihara M, Tsukamoto R, Tokunaga S, Tamura D,
Shinke H, Kobayashi K, Sakai Y, Nishimura Y.
Utility of cell blocks obtained by catheter aspiration via
a guide sheath during endobronchial ultrasonography.
Respir Investig. 2017;55(2):161-165.

Tohda Y, Iwanaga T, Sano H, Kume H, Hirata K, Ohkura N, Tachibana I,
Nishimura Y, Matsumoto H, Minakata Y, Yoshikawa M, Fujimura M;
Kansai and Hokuriku Academy for Asthma Treatment.
Improved quality of life in asthma patients under long-term therapy:
Assessed by AHQ-Japan.
Int J Clin Pract. 2017;71(1). doi: 10.1111/ijcp.12898. Epub 2016 Dec 9.

Takahashi T, Yamanaka T, Seto T, Harada H, Nokihara H, Saka H, Nishio M,
Kaneda H, Takayama K, Ishimoto O, Takeda K, Yoshioka H, Tachihara M,
Sakai H, Goto K, Yamamoto N.
Prophylactic cranial irradiation versus observation in patients with extensive-disease
small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial.
Lancet Oncol. 2017 May;18(5):663-671.

Kunimasa K, Nagano T, Shimono Y, Dokuni R, Kiriu T, Tokunaga S, Tamura D,
Yamamoto M, Tachihara M, Kobayashi K, Satouchi M, Nishimura Y.
Glucose metabolism-targeted therapy and withaferin A are effective for epidermal
growth factor receptor tyrosine kinase inhibitor-induced drug-tolerant persisters.
Cancer Sci. 2017;108(7):1368-1377.

Tokunaga S, Nagano T, Kobayashi K, Katsurada M, Nakata K, Yamamoto M,
Tachihara M, Kamiryo H, Yokozaki H, Nishimura Y.
Amphiregulin as a Novel Resistance Factor for Amrubicin in Lung Cancer Cells.
Anticancer Res. 2017;37(5):2225-2231.

Kiriu T, Tamura D, Tachihara M, Sekiya R, Hazama D, Katsurada M,
Nakata K, Nagano T, Yamamoto M, Kamiryo H, Kobayashi K, Nishimura Y.
Successful Osimertinib Rechallenge with Steroid Therapy after
simertinib-induced Interstitial Lung Disease: A Case Report.
Intern Med. 2017 in press

(Book) Katsurada M, Izumo T. (2017).
Chapter 9 Anesthesia for Bronchoscopy.
Izumo T, Sasada S, Aso T, Nasu K, Arai Y. (Eds.) Respiratory Endoscopy.
Singapore: Springer, pp. 53-58.

(Book) Katsurada M, Izumo T. (2017).
Chapter 22 The Dose and Risk Factors for Radiation Exposure from X-Ray
Fluoroscopy During EBUS-GS for Peripheral Pulmonary Lesions.
Izumo T, Sasada S, Aso T, Nasu K, Arai Y. (Eds.) Respiratory Endoscopy.
Singapore: Springer, pp. 53-58.

経気管支肺生検で診断しえた異所性石灰化症の長期経過観察例
羽間大祐, 立原素子, 國政啓, 堂國良太, 桐生辰徳, 田村大介,
櫨木暢子, 上領博, 小林和幸, 西村善博
気管支学39巻1号 Page64-70, 2017

成人T細胞白血病リンパ腫の診断にセルブロックが有用であった1例
山本正嗣、里内美弥子、高瀬直人、伊藤彰一、河良崇、河野祐子、
浦田佳子、島田天美子、服部剛弘、根來 俊一
気管支学39巻2号 Page165-169, 2017

急性呼吸不全を呈した抗OJ抗体の1例
関谷怜奈、西尾智尋、冨岡洋海、山下修司
日呼吸誌6 (4):235-239,2017

(総説)職業関連呼吸器疾患 じん肺,悪性胸膜中皮腫を中心に概観する
桂田雅大、西村善博
Hospitalist 5巻2号,291-301 2017

(総説)再生検の現状と課題(リキッドバイオプシーを含めて)
安田裕一郎、里内美弥子
日本臨牀 75(7): 1121-1127, 2017

(書籍)肺がん(12 肺がんの治療 4高齢者肺がんに対する治療 ①非小細胞がん)
山本正嗣 里内美弥子
インフォームドコンセントのための図説シリーズ改訂5版、2017年

(書籍)胸郭の異常(漏斗胸・鳩胸)
西村善博
内科学第11版 矢先義雄編 朝倉書店 861-862, 2017

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2016

Koyama H, Ohno Y, Fujisawa Y, Seki S, Negi N, Murakami T, Yoshikawa T,
Sugihara N, Nishimura Y, Sugimura K.
3D lung motion assessments on inspiratory/expiratory thin-section CT:
Capability for pulmonary functional loss of smoking-related COPD in
comparison with lung destruction and air trapping.
Eur J Radiol. 2016 85(2):352-9.

Kunimasa K, Kobayashi K, Inoue N, Nishimura Y.
Haemoptysis as a Presenting Symptom of Thoracic Aneurysm Dissection.
Intern Med. 2016;55(15):2117-8.

Kunimasa K, Tachihara M, Tamura D, Tokunaga S, Nakata K, Hazeki N,
Kamiryo H, Kobayashi K, Sakai Y, Nishimura Y.
Diagnostic utility of additional conventional techniques after
endobronchial ultrasonography guidance during transbronchial biopsy.
Respirology. 2016;21(6):1100-5.

Fukuhara N, Tachihara M, Tanino Y, Saito J, Sato S, Nikaido T, Misa K,
Fukuhara A, Wang X, Ishida T, Onami T, Munakata M.
Cholesteryl palmitate crystals in bronchoalveolar lavage fluid smears as
a possible prognostic biomarker for chronic interstitial pneumonia: A
preliminary study.
Respir Investig. 2016;54(2):109-15.

Takahama T, Sakai K, Takeda M, Azuma K, Hida T, Hirabayashi M, Oguri T,
Tanaka H, Ebi N, Sawa T, Bessho A, Tachihara M, Akamatsu H, Bandoh S,
Himeji D, Ohira T, Shimokawa M, Nakanishi Y, Nakagawa K, Nishio K. 
Detection of the T790M mutation of EGFR in plasma of advanced non-small
cell lung cancer patients with acquired resistance to tyrosine kinase
inhibitors (West Japan oncology group 8014LTR study).
Oncotarget. 2016;7(36):58492-58499.

Rider CF, Yamamoto M, Günther OP, Hirota JA, Singh A, Tebbutt SJ,
Carlsten C.
Controlled diesel exhaust and allergen coexposure modulates microRNA and
gene expression in humans: Effects on inflammatory lung markers.
J Allergy Clin Immunol. 2016;138(6):1690-1700.

Takase N, Hattori Y, Kiriu T, Itoh S, Kawa Y, Yamamoto M,
Urata Y, Shimada T, Tsujino K, Soejima T, Negoro S, Satouchi M.
Concurrent chemoradiotherapy with cisplatin and S-1 or vinorelbine for patients
with stage III unresectable non-small cell lung cancer: A retrospective study.
Respir Investig. 2016;54(5):334-40.

Terashita T, Kobayashi K, Nagano T, Kawa Y, Tamura D, Nakata K,
Yamamoto M, Tachihara M, Kamiryo H, Nishimura Y.
Administration of JTE013 abrogates experimental asthma by regulating
proinflammatory cytokine production from bronchial epithelial cells.
Respir Res. 2016;17(1):146.

Allergic bronchopulmonary aspergillosis(ABPA)様の画像を呈した
ピーナッツ気管支異物の一例
関谷怜奈,小林和幸,堂國良太,羽間大祐,桐生辰徳,國政啓,田村大介,
立原素子,上領博,西村善博
気管支学38巻6号, 515-520, 2016

(総説)呼吸機能検査でできること
西村善博
呼吸器内科30巻4号, 342-348, 2016

(総説) 診断がつかないせき、対応に困るせき
桂田雅大、西村善博
JOHNS 32巻8号, 941-945, 2016

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2015

Asano F, Shinagawa N, Ishida T, Tsuzuku A, Tachihara M, Kanazawa K,
Yamada N, Oizumi S, Moriya H. Virtual Bronchoscopic Navigation Improves
the Diagnostic Yield of Radial-Endobronchial Ultrasound for Peripheral
Pulmonary Lesions with Involved Bronchi on CT.
Intern Med 2015;54: 1021-1025.

Otsuka T, Mori M, Yano Y, Uchida J, Nishino K, KaJi R, Hata A, Hattori
Y, Urata Y, Kaneda T, Tachihara M, Imamura F, Katakami N, Negoro S,
Morita S, Yokota S. Effectiveness of Tyrosine Kinase Inhibitors in
Japanese Patients with Non-small Cell Lung Cancer Harboring Minor
Epidermal Growth Factor Receptor Mutations: Results from a Multicenter
Retrospective Study (HANSHIN Oncology Group 0212).
Anticancer research 2015;35: 3885-3892.

Nishino K, Imamura F, Kumagaia T, Katakami N, Hata A, Okuda C, Urata Y,
Hattori Y, Tachihara M, Yokota S, Nishimura T, Kaneda T, Satouchi M,
Morita S, Negoro S.
A randomized phase II study of bevacizumab in combination with docetaxel
or S-1 in patients with non-squamous non-small-cell lung
cancer previously treated with platinum based chemotherapy (HANSHIN
Oncology Group 0110).
Lung Cancer. 2015; 89 2015:146–153.

Okuma Y, Tanuma J, Kamiryo H, Kojima Y, Yotsumoto M, Ajisawa A, Uehira
T, Nagai H, Takeda Y, Setoguchi Y, Okada S.
A multi-institutional study of clinicopathological features and
molecular epidemiology of epidermal growth factor receptor mutations in
lung cancer patients living with human immunodeficiency virus infection.
J Cancer Res Clin Oncol. 2015 Mar 24.

Kunimasa K, Tachihara M, Terashita T, Nishimura Y
Gradually Enlarging Crazy-paving Appearance.
Intern Med. 2015;54(21):2791-2.

呼吸器抄読会 神戸大学大学院医学研究科内科学講座呼吸器内科学分野
呼吸 34巻1号、120、2015

COPD診療にいかに取り組むか COPDの診断法と治療
西村善博
兵庫県医師会医学雑誌 第58巻1号 4-6,2015

喘息発作による救急外来受診後の再受診状況の現状と課題
櫨木暢子,小林和幸,船田泰弘,寺田忠之,中谷裕司,岡勝巳,金岡正樹,岸本信康,黒坂文武,田中明,西庵利彦,望月吉郎,八木一之,山田充宏,山本裕之,薄木洋明,大本明義,西村善博
兵庫県医師会医学雑誌 第58巻第1号 44-49,2015

Picture in Clinical
Hematology(No.85) FDG-PETで両肺にびまん性異常集積を認めた血管内大細胞型B細胞リンパ腫.
阿部緑生,立原素子,植松学,勝浦豊,田中端子,杉野隆,小川一英.
臨床血液2015;56:749.

左上葉腫瘤に対する経気管支生検に加えて,右肺門リンパ節の経気管支穿刺吸引細胞診を行うことで診断し得た同時多発肺癌の1例
高瀬直人,里内美弥子,桐生辰徳,西村春佳,伊藤彰一,内堀健,山本正嗣,奥野恵子,浦田佳子,島田天美子,服部剛弘,根來俊一
気管支学 37巻5号,537-543,2015

気管支擦過細胞診にてアレルギー性気管支肺アスペルギルス症が疑われた1例
寺下智美,立原素子,上原慶一郎,酒井康裕,西村善博
臨床細胞学会,54巻,221-222,2015

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2014

Hatakeyama Y, Kobayashi K, Nagano T, Tamura D, Yamamoto M, Tachihara M, Kotani Y, Nishimura Y.
Synergistic effects of pemetrexed and amrubicin in non-small cell lung cancer cell lines: Potential for combination therapy.
Cancer Lett. 2014 Feb 1;343(1):74-9.

Tachihara M, Kobayashi K, Ishikawa Y, Hori S, Tamura D, Otera H, Funada Y, Nishimura Y.
Successful Crizotinib Rechallenge After Crizotinib-induced Interstitial Lung Disease.
Jpn J Clin Oncol. 2014 Aug;44(8):762-4.

Nagano T, Edamatsu H, Kobayashi K, Takenaka N, Yamamoto M, Sasaki N, Nishimura Y, Kataoka T.
Phospholipase Cε, an effector of Ras and Rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma.
PLoS One. In press.

Motoko Tachihara, Takashi Ishida, Naoko Fukuhara, Yayoi Inokoshi, Atsuro Fukuhara, Kazue Saito, Taeko Ishii, Kenya Kanazawa, Yutaka Katsuura, Mitsuru Munakata.
Catheter Spray of Lidocaine: a Randomized Study of Topical Anesthesia for Flexible Bronchoscopy.
JJSRE. 2014;36:359-363.

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2013

Hazeki N, Kobayashi K, Shinke H, Yamamoto M, Ohta M, Nishimura Y.
Semipermeable membrane dressings are usable with nicotine transdermal system and do not interfere with nicotine absorption.
Intern Med. 2013;52(24):2743-8.

Sugawara S, Maemondo M, Tachihara M, Inoue A, Ishimoto O, Sakakibara T, Usui K, Watanabe H, Matsubara N, Watanabe K, Kanazawa K, Ishida T, Saijo Y, Nukiwa T.
Randomized phase II trial of uracil/tegafur and cisplatin versus vinorelbine and cisplatin with concurrent thoracic radiotherapy for locally advanced unresectable stage III non-small-cell lung cancer: NJLCG 0601.
Lung cancer 2013;81: 91-96.

Shinke H, Yamamoto M, Hazeki N, Kotani Y, Kobayashi K, Nishimura Y.
Visualized changes in respiratory resistance and reactance along a time axis in smokers: A cross-sectional study.
Respir Investig. 2013 Sep;51(3):166-74.

Tamura D, Arao T, Nagai T, Kaneda H, Aomatsu K, Fujita Y, Matsumoto K, De Velasco MA, Kato H, Hayashi H, Yoshida S, Kimura H, Maniwa Y, Nishio W, Sakai Y, Ohbayashi C, Kotani Y, Nishimura Y, Nishio K.
Slug increases sensitivity to tubulin-binding agents via the downregulation of bIII and bIVa-tubulin in lung cancer cells
Cancer Med. 2013 Apr;2(2):144-54.

Yamamoto M, Singh A, Sava F, Pui M, Tebbutt SJ, Carlsten C.
MicroRNA
expression in response to controlled exposure to diesel exhaust: attenuation by the antioxidant N-acetylcysteine in a randomized crossover study.
Environ Health Perspect. 2013 Jun;121(6):670-5.

Singh A, Yamamoto M, Kam SH, Ruan J, Gauvreau GM, O'Byrne PM, FitzGerald JM, Schellenberg R, Boulet LP, Wojewodka G, Kanagaratham C, De Sanctis JB, Radzioch D, Tebbutt SJ.
Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses.
PLoS One. 2013 Jul 2;8(7):e67907

Sakai Y, Yamasaki T, Kusakabe Y, Kasai D, Kotani Y, Nishimura Y, Itoh T.
Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature.
Multidiscip Respir Med. 2013 Jul 18;8(1):47.

Shinke H, Yamamoto M, Hazeki N, Kotani Y, Kobayashi K, Nishimura Y.
Visualized changes in respiratory resistance and reactance along a time axis in smokers: A cross-sectional study.
Respir Investig. 2013 Sep;51(3):166-74.

Hazeki N, Kobayashi K, Shinke H, Yamamoto M, Ohta M, Nishimura Y
Semipermeable membrane dressings are usable with nicotine transdermal system and do not interfere with nicotine absorption.
Intern. med. In press.

邦文原著論文、総説など
仮想気管支鏡ナビゲーション併用によるTBNAにて確定診断しえた肺MALTリンパ腫の1例.
立原素子, 田村大介, 畠山由起久, 新家治子,堀朱矢, 石川結美子,櫨木暢子,小林和幸, 船田泰弘, 小谷義一, 西村善博
気管支学 in press 2013

特集:呼吸器疾患の診断・治療(Ⅰ)気管支拡張症
德永俊太郎、西村善博
医学と薬学 69巻1号,2013

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2012

Kurata T, Hirashima T, Iwamoto Y, Kawaguchi T, Ikeda N, Tsuboi M, Sawa T, Ishiguro T, Aoki T, Kotani Y, Nakagawa K, Fukuoka M.
A phase I/II study of carboplatin plus gemcitabine for elderly patients with advanced non-small cell lung cancer: West Japan Thoracic Oncology Group Trial (WJTOG) 2905.
Lung Cancer. 2012 Jul;77(1):110-5.

Nagano T, Kotani Y, Fujii O, Demizu Y, Niwa Y, Ohno Y, Nishio W, Itoh T, Murakami M, Nishimura Y.
A case of acute exacerbation of idiopathic pulmonary fibrosis after proton beam therapy for non-small cell lung cancer.
Jpn J Clin Oncol. 2012 Oct;42(10):965-9. Epub 2012 Jul 23.

Koyama H, Ohno Y, Nishio M, Takenaka D, Yoshikawa T, Matsumoto S, Nishimura Y, Sugimura K.
Three-dimensional airway lumen volumetry: comparison with bronchial wall area and parenchymal densitometry in assessment of airway obstruction in pulmonary emphysema.
Br J Radiol. 2012 Dec;85(1020):1525-32.

Tachihara M, Nikaido T, Wang X, Ishii T, Saito K, Sekine S, Tanino Y, Ishida T, Munakata M.
Four Cases of Trousseau's Syndrome Associated with Lung Adenocarcinoma.
Intern Med. 2012;51:1099-1102.

Yamamoto M, Singh A, Ruan J, Gauvreau GM, O'Byrne PM, Carlsten CR, FitzGerald JM, Boulet LP, Tebbutt SJ.
Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge.
BMC Genomics. 2012 Nov 21;13:655

Yamamoto M, Nagano T, Okuno K, Nakata K, Takenaka K, Kobayashi K, Ishikawa Y, Sakashita A, Kotani Y, Funada Y, Nishimura Y.
An open-label, prospective clinical study to evaluate the efficacy of prophylactic antibiotics after diagnostic bronchoscopy
Kobe J Med Sci. 2012 Dec 13;58(4):E110-8.

邦文原著論文、総説など
緩和ケアチーム介入によるがん患者QOLの変化についての検討
新家治子, 坂下明大,石橋有希,太田垣加奈子,藤原由佳,五百蔵武士,田宮裕子,小谷義一,向原徹,南博信,西村善博
Palliative Care Research 2012; 7(2): 368-73

1日1回型フェンタニル貼付剤にオピオイド・ローテーションしたがん疼痛症例の検討
坂下明大,新家治子,太田垣加奈子,石橋有希,紀平裕美,打保裕子,五百蔵武士,高野由美子,西村善博
ペインクリニック,33巻,841-846,2012

集検喀痰細胞診で発見された喉頭癌と早期中心型肺癌の細胞像の比較検討
立原素子,神尾淳子,佐藤丈晴,室井祥江, 柴田眞一,森村 豊,石田 卓,棟方 充
臨床細胞学会.2012;51:7-12.

プロクロルペラジンにより横紋筋融解症を来した1例
紀平裕美, 打保裕子, 太田垣加奈子, 坂下明大, 久米学, 平野剛, 西村善博, 平井みどり
日本緩和医療薬学雑誌, 5巻3号, 61-64, 2012

診断に苦慮した原発性心臓腫瘍の1例
堀朱矢,小谷義一,笠井大介,新家治子,河良崇,畠山由記久,山本聡美,大林千穂,西村善博
日本胸部臨床,71巻,292-298,2012

【悪性腫瘍-その合理的な画像診断の進め方】 再発チェックを合理的に行う
には 肺癌
大野良治,関紳一郎,西尾瑞穂,尾西由美子,神山久信,吉川武,松本純明,真庭謙昌,西村善博,杉村和朗
臨床画像,28巻,786-794,2012

喫煙と歯科疾患
櫨木暢子,小林和幸,小谷義一,西村善博
兵庫県歯科医師会機関誌「歯界月報」2012年8月号(733号)

薬剤師に対する喘息患者への吸入指導に対するアンケート調査
堀 朱矢,西村 善博,小林 和幸,深堀 隆,石原 亮介,片山 覚
兵庫県医師会医学雑誌,  55巻1号, 22-26, 2012

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2011

Non-small cell carcinoma: Comparison of postoperative intra- and extrathoracic recurrence assessment capability of qualitatively and/or quantitatively assessed FDG-PET/CT and standard radiological examinations.
Onishi Y, Ohno Y, Koyama H, Nogami M, Takenaka D, Matsumoto K, Yoshikawa T, Matsumoto S, Maniwa Y, Nishimura Y, Sugimura K.
Eur. J. Radiol. 2011 79: 473-479

MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell.
Doi T, Maniwa Y, Tanaka Y, Tane S, Hashimoto S, Ohno Y, Nishio W, Nishimura Y, Ohbayashi C, Okita Y, Hayashi Y, Yoshimura M.
Exp. Mol. Pathol. 2011 90: 91-96

Differentiation of malignant and benign pulmonary nodules with quantitative first-pass 320-detector row perfusion CT versus FDG PET/CT.
Ohno Y, Koyama H, Matsumoto K, Onishi Y, Takenaka D, Fujisawa Y, Yoshikawa T, Konishi M, Maniwa Y, Nishimura Y, Ito T, Sugimura K.
Radiology 2011 258: 599-609

Quantitative bronchial luminal volumetric assessment of pulmonary function loss by thin-section MDCT in pulmonary emphysema patients.
Koyama H, Ohno Y, Yamazaki Y, Onishi Y, Takenaka D, Yoshikawa T, Nishio M, Matsumoto S, Murase K, Nishimura Y, Sugimura K.
Eur. J. Radiol., 2011 81: 384-388

Comparison of capability of dynamic O(2)-enhanced MRI and quantitative thin-section MDCT to assess COPD in smokers.
Ohno Y, Koyama H, Yoshikawa T, Matsumoto K, Aoyama N, Onishi Y, Takenaka D, Matsumoto S, Nishimura Y, Sugimura K.
Eur. J. Radiol. 2011 Mar 8. [Epub ahead of print]

A metabolomic approach to lung cancer.
Hori S, Nishiumi S, Kobayashi K, Shinohara M, Hatakeyama Y, Kotani Y, Hatano N, Maniwa Y, Nishio W, Bamba T, Fukusaki E, Azuma T, Takenawa T, Nishimura Y, Yoshida M.
Lung Cancer 2011 74: 284-292

Antigen-specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells.
Ishikawa Y, Kobayashi K, Yamamoto M, Nakata K, Takagawa T, Funada Y, Kotani Y. Karasuyama H, Yoshida M, Nishimura Y.
Respir. Res. 2011 10: 42-51

Reduced-dose chest CT with 3D automatic exposure control vs. standard chest CT: Quantitative assessment of emphysematous changes in smokers' lung parenchyma.
Koyama H, Ohno Y, Yamazaki Y, Matsumoto K, Onishi Y, Takenaka D, Yoshikawa T, Nishio M, Matsumoto S, Murase K, Nishimura Y, Sugimura K.
Eur. J. Radiol. 2011 Jun 22. [Epub ahead of print]

Chemotherapy improves thymoma-associated graft-versus- host-disease-like erythroderma.
Nagano T, Kotani Y, Kobayashi K, Tomita N, Nakata K, Sakashita A, Funada Y, Nagai H, Itoh T, Nishimura Y.
BMJ Case Reports 2011 May 10. [Epub ahead of print]

N stage disease in patients with non-small cell lung cancer: Efficacy of quantitative and qualitative assessment with STIR turbo spin-echo imaging, diffusion-weighted MR imaging, and fluorodeoxyglucose PET/CT.
Ohno Y, Koyama H, Yoshikawa T, Nishio M, Aoyama N, Onishi Y, Takenaka D, Matsumoto S, Maniwa Y, Nishio W, Nishimura Y, Itoh T, Sugimura K.
Radiology 2011 261: 605-615

Long-term outcome after multidisciplinary approach for leptomeningeal carcinomatosis in a non-small cell lung cancer patient with poor performance status.
Nagano T, Kotani Y, Kobayashi K, Hatakeyama Y, Hori S, Kasai D, Funada Y, Nishimura H, Kondoh T, Nishimura Y.
Intern. Med. 2011 50: 3019-3022.

Successful erlotinib treatment for a patient with gefitinib-related hepatotoxicity and lung adenocarcinoma refractory to intermittently administered gefitinib.
Nagano T, Kotani Y, Kobayashi K, Katsurada M, Hatakeyama Y, Hori S, Tamura D, Kasai D, Funada Y, Nishimura Y.
Case Reports in Pulmonology 2011, Article ID 812972.

Early diagnosis of health damage in arc welders based on their serum ferritin level.
Sera K, Nishimura Y, Hayashi C, Nishio H.
Open Journal of Internal Medicine 2011 1: 77-79

Comparison of 3-D-visualized respiratory impedance patterns and structural change detected by CT in smokers.
Shinke H, Yamamoto M, Hazeki N, Kobayashi K, Funada Y, Kotani Y, Ohno Y, Nishimura Y.
5th International Workshop for Pulmonary Functional Imaging, 2011

Prevalence of chronic obstructive pulmonary disease in inpatients with cardiovascular disease.
Kawa Y, Kobayashi K, Nakata K, Shinke H, Funada Y, Kotani Y, Nishimura Y.
106th ATS International Conference, 2011

Relevance between respiratory impedance pattern and structural changes in smoking-induced expiratory flow limitation.
Shinke H, Yamamoto M, Hazeki N, Kawa Y, Kobayashi K, Funada Y, Kotani Y, Nishimura Y.
106th ATS International Conference, 2011

Crucial role of phospholipase Cε in the development of asthma in mice.
Nagano T, Edamatsu H, Kobayashi K, Nishimura Y, Kataoka T.
31st ERS Annual Congress, 2011

Clinical utility of EGFR gene mutation analysis with cytological materials from bronchoscopy not histological materials.
Nakata K, Kotani Y, Hatakeyama Y, Tomita N, Hazeki N, Sakashita A, Kobayashi K, Funada Y, Nishimura Y.
31st ERS Annual Congress, 2011

Ohno Y, Koyama H, Yoshikawa T, Nishio M, Aoyama N, Onishi Y, Takenaka D, Matsumoto S, Maniwa Y, Nishio W, Nishimura Y, Itoh T, Sugimura K.
N stage disease in patients with non-small cell lung cancer:
Efficacy of quantitative and qualitative assessment with STIR turbo spin-echo imaging, diffusion-weighted MR imaging, and fluorodeoxyglucose PET/CT.
Radiology 2011 261: 605-615

Tachihara M, Misa K, Uematsu M, Minemura H, Katsuura Y, Ishida T, Munakata M. Increase of Ascites and Pleural Effusion Misleading Assessment of Antitumor Response to Erlotinib in Adenocarcinoma of the Lung.
J Clin Oncol. 2011;29:e675-7.

邦文原著論文、総説など
肺胞洗浄液のRT-PCR検査により診断しえた重症新型インフルエンザA(H1N1)2009ウイルス肺炎の1例
桂田直子,大西尚,山本聡美,木南佐織,西馬照明,西村善博,荒川創一
感染症学雑誌,85巻,172-175,2011

肺原発筋上皮癌の1例
奥野恵子,小林和幸,吉村雅裕,大野良治,大林千穂,西村善博
肺癌,51巻,77-83,2011

気管挿管の関与が考えられた喉頭炎症性肉芽の1例
奥野恵子,杉村春佳, 小林和幸,小谷義一,西村善博
気管支学,33巻,306-310,2011

急速な増大を認めた小細胞型悪性胸膜中皮腫の1例
石川結美子,小林和幸,船田泰弘,山本正嗣,堀朱矢,新家治子,畠山由記久,坂下明大,小谷義一,西村善博,大林千穂
気管支学,33巻,435-442,2011

兵庫県喘息死ゼロ作戦-2011年実績報告と今後の展開-
西村善博,小林和幸,片山覚
兵庫県医師会医学雑誌,54巻,32-35, 2011

腸管出血性大腸菌感染症
笠井大介  
臨床医のための消化管内視鏡アトラス 医薬ジャーナル社 2011年

局所再発を繰り返し、外科切除にて混合型小細胞肺癌と診断した1例
立原素子, 渡邉香奈, 横内浩, 鈴木弘行, 石田卓, 棟方充
肺癌. 2011;51:820-824.

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2010

Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1 in a mouse model of non-small cell lung cancer.
Nagano T, Yasunaga M, Goto K, Kenmotsu H, Koga Y, Kuroda J, Nishimura Y, Sugino T, Nishiwaki Y, Matsumura Y.
Int J Cancer. 2010 Dec 1;127(11):2699-706.

The antitumor activity of NK012, an SN-38-incorporating micelle, in combination with bevacizumab against lung cancer xenografts.
Kenmotsu H, Yasunaga M, Goto K, Nagano T, Kuroda J, Koga Y, Takahashi A, Nishiwaki Y, Matsumura Y.
Cancer. 2010 Oct 1;116(19):4597-604.

The inhibitory effects of intravenous administration of rabbit immunoglobulin G on airway inflammation are dependent upon Fcγ receptor IIb on CD11c(+) dendritic cells in a murine model.
Yamamoto M, Kobayashi K, Ishikawa Y, Nakata K, Funada Y, Kotani Y, Masuda A, Takai T, Azuma T, Yoshida M, Nishimura Y.
Clin Exp Immunol. 2010 Sep 1. doi: 10.1111/j.1365-2249.2010.04243.x. [Epub ahead of print]

Bortezomib potentially inhibits cellular growth of vascular endothelial cells through suppression of G2/M transition.
Tamura D, Arao T, Tanaka K, Kaneda H, Matsumoto K, Kudo K, Aomatsu K, Fujita Y, Watanabe T, Saijo N, Kotani Y, Nishimura Y, Nishio K.
Cancer Sci. 2010 Jun;101(6):1403-8. Epub 2010 Mar 15.

A case of hard metal lung disease resembling a hypersensitive pneumonia in radiological images.
Okuno K, Kobayashi K, Kotani Y, Ohnishi H, Ohbayashi C, Nishimura Y.
Intern Med. 2010;49(12):1185-9. Epub 2010 Jun 15.

Non-small cell carcinoma: Comparison of postoperative intra- and extrathoracic recurrence assessment capability of qualitatively and/or quantitatively assessed FDG-PET/CT and standard radiological examinations.
Onishi Y, Ohno Y, Koyama H, Nogami M, Takenaka D, Matsumoto K, Yoshikawa T, Matsumoto S, Maniwa Y, Nishimura Y, Sugimura K.
Eur J Radiol. 2010 May 21. [Epub ahead of print]

Randomized phase II study of two different schedules of gemcitabine and oral S-1 in chemo-naïve patients with advanced non-small cell lung cancer.
Satouchi M, Kotani Y, Katakami N, Shimada T, Urata Y, Yoshimura S, Funada Y, Hata A, Ando M, Negoro S.
J Thorac Oncol. 2010 May;5(5):696-701

The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner.
Nakata K, Kobayashi K, Ishikawa Y, Yamamoto M, Funada Y, Kotani Y, Blumberg RS, Karasuyama H, Yoshida M, Nishimura Y.
Biochem Biophys Res Commun. 2010 Apr 30;395(2):238-43. Epub 2010 Apr 1.

Sphingosine kinase 1 regulates mucin production via ERK phosphorylation.
Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y, Jahangeer S, Nakamura S, Nishimura Y.
Pulm Pharmacol Ther. 2010 Feb;23(1):36-42. Epub 2009 Oct 14.

邦文原著
低用量オキシコドンからフェンタニルパッチへのオピオイド・ローテーションの安全性の検討
坂下明大, 石川結美子, 奥野恵子, 櫨木暢子, 玉尾夏実, 河野祐子, 小林和幸, 船田泰弘, 小谷義一, 西村善博
ペインクリニック 31巻5号 Page649-653, 2010

邦文その他
【アレルギー疾患と脂質メディエーター】 スフィンゴシン1リン酸代謝と気管支喘息
西馬照明, 西村善博
臨床免疫・アレルギー科 54巻1号 Page65-71, 2010

【睡眠と生活習慣病】 睡眠と急性冠症候群
櫨木暢子, 小林和幸, 西村善博, 平田健一
成人病と生活習慣病 40巻4号 Page395-397, 2010

【分子標的治療薬の副作用マネージメント】II-B-3.循環器障害
永野達也、後藤功一
南江堂 in press, 2010

家族性肺胞低換気症候群
船田泰弘
呼吸, 29(2) : 163-166, 2010.

国内学会
胸腔鏡下に切除した後縦隔発生Castleman病の1例
橋本章太郎, 真庭謙昌, 西尾渉, 吉村雅裕, 船田泰弘, 小谷義一, 西村善博, 竹中大祐, 大野良治, 上原慶一郎, 伊藤智雄
第91回日本肺癌学会関西支部会 2010年1月30日 大津

メタボロミクスを用いた肺癌バイオマーカーの探索
岡本朱矢,小林和幸,山本正嗣,船田泰弘,小谷義一,西村善博,西海信,篠原正和,吉田優
第6回呼吸器バイオマーカー研究会 2010年03月27日 東京

新型インフルエンザ 簡易検査では繰り返し陰性であったが,肺胞洗浄液のPCR検査により診断しえた重症新型インフルエンザウイルス肺炎の1例
大西尚, 小澤一之, 山本聡美, 岩佐直子, 木南佐織, 西馬照明, 西村善博, 荒川創一
第84回日本感染症学総会・学術講演会 2010年4月6日 京都

アレルギー性気道炎症におけるFcRnの役割
中田恭介, 小林和幸, 石川結美子, 岡本朱矢, 山本正嗣, 坂下明大, 船田泰弘, 小谷義一, 吉田優, 西村善博
第50回日本呼吸器学会学術講演会 2010年4月24日 京都

III期非小細胞肺癌に対する放射線同時併用毎週投与イリノテカン(I)+カルボプラチン(C)・パクリタキセル(P)+Cの第III相無作為化比較試験(WJTOG 0105)
横田総一郎, 工藤新三, 樋田豊明, 浅見和弘, 坂英雄, 牛島淳, 小谷義一, 後藤功, 高山浩一, 川瀬一郎, 中野孝司, 木村弘, 西村恭昌, 中川和彦
第50回日本呼吸器学会学術講演会 2010年4月24日 京都

EGFR変異を有する非小細胞肺癌(NSCLC)に対するゲフィチニブ(G)とシスプラチン(C)+ドセタキセル(D)の比較第III相試験(WJTOG3405)
平島智徳, 光冨徹哉, 浅見和弘, 齋藤博, 菓子井達彦, 横山彰仁, 森永亮太郎, 山口悦郎, 小谷義一, 阿部直, 伊達洋至, 木村弘, 中川和彦
第50回日本呼吸器学会学術講演会 2010年4月24日 京都

メタボローム解析を用いた肺癌バイオマーカーの探索
岡本朱矢, 小林和幸, 西海信, 畠山由記久, 河良崇, 永野達也, 石川結美子, 中田恭介, 倉本衣美, 櫨木暢子, 山本正嗣, 坂下明大, 船田泰弘, 小谷義一, 橋本章太郎, 真庭謙昌, 西尾渉, 篠原正和, 吉田優, 西村善博
第50回日本呼吸器学会学術講演会 2010年4月25日 京都

喫煙者における末梢気道病変のモストグラフによる評価
山本正嗣, 桂田雅大, 小林和幸, 櫨木暢子, 坂下明大, 船田泰弘, 小谷義一, 西村善博
第50回日本呼吸器学会学術講演会 2010年4月25日 京都

閉塞型睡眠時無呼吸症候群におけるモストグラフによる呼吸抵抗の解析
櫨木暢子, 山本正嗣, 倉本衣美, 桂田雅大, 小林和幸, 坂下明大, 船田泰弘, 小谷義一, 西村善博
第50回日本呼吸器学会学術講演会 2010年4月25日 京都

Bacillus属検出患者の背景調査と感染危険因子の探索
山下和彦, 阿部泰尚, 中村正邦, 田中健太, 植田貴史, 大松秀明, 平野剛, 森岡一郎, 中野雄造, 八幡眞理子, 瀬尾靖, 吉田弘之, 李宗子, 西村善博, 平井みどり, 荒川創一
題58回日本化学療法学会総会 2010年6月2日 長崎

悪性腫瘍患者における緩和ケアニーズのスクリーニングに関する検討
坂下明大,石橋有希,太田垣加奈子,藤原由佳,五百蔵武士,田宮裕子,西村善博,小谷義一,向原徹,南博信
第15回日本緩和医療学会学術大会 2010年6月19日 東京

Snailに誘導される上皮間葉移行は肺癌のチュブリン作用系抗癌剤の感受性を規定する
田村大介 荒尾徳三 永井知行 青松圭一 金田裕靖 松本和子 工藤可苗
坂井和子 木村英晴 藤田至彦 古田一行  西条長宏 西尾和人
第14回日本がん分子標的治療学会学術集会 2010年7月8日 東京

GVHD様反応による紅皮症を呈した浸潤性胸腺腫の1例
冨田菜々子,中田恭介,畠山由記久,永野達也,山本聡美,櫨木暢子,船田泰弘,小谷義一,西村善博
第75回日本呼吸器学会近畿地方会 2010年7月17日

びまん性粒状陰影と空洞性病変を伴った粘液産生型肺腺癌の1例
山本聡美,櫨木暢子,冨田菜々子,中田恭介,船田泰弘,小谷義一, 西村善博
第75回日本呼吸器学会近畿地方会 2010年7月17日

ニコチンパッチの皮膚障害に対するテガダームの有用性の検討
櫨木暢子,小林和幸,船田泰弘,小谷義一 西村善博
第192回日本内科学会近畿地方会 2010年9月11日 大阪

SNAI2-mediated epithelial mesenchymal transition increases the drug sensitivity to tubulin binding agents in lung cancer
Daisuke Tamura Tokuzo Arao, Tomoyuki Nagai, Kazuyuki Furuta, Kazuko Sakai, Kanae Kudo, Hiroyasu Kaneda, Keiichi Aomatsu, Yoshihiko Fujita, Kazuko Matsumoto, Nagahiro Saijo, and Kazuto Nishio
第69回日本癌学会学術総会 2010年9月23日 大阪

緩和ケアチームによる薬物療法がもたらす患者QOLへの影響
―EORTC QLQ-C15-PALを用いた臨床研究―
打保裕子,五百蔵武士,紀平裕美,坂下明大,石橋有希,太田垣加奈子,藤原由佳,槇本博雄,平野剛,西村善博,平井みどり
第4回緩和医療薬学会年会 2010年9月26日 鹿児島

小児緩和ケアにおける疼痛評価とそれに基づく薬物療法との関係
〜仙骨原発primitive neuroectodermal tumor症例に対する介入からみえた緩和ケアチーム薬剤師の課題〜
紀平裕美,打保裕子,五百蔵武士,太田垣加奈子,石橋有希,藤原由佳,坂下明大,久米学,平野剛,西村善博,平井みどり
第4回緩和医療薬学会年会 2010年9月26日 鹿児島

がん疼痛治療中にプロクロルペラジンが原因と考えられる横紋筋融解症をきたした一例
坂下明大
JPAP第14回ペインカンファレンス 10月2日 大阪

国際学会
Intratracheal instillation of antigen specific IgG inhibits an allergic airway inflammation via Fcγ receptor IIB on dendritic cells
Yumiko Ishikawa, Kazuyuki Kobayashi, Masatsugu Yamamoto, Kyosuke Nakata, Emi Kuramoto, Yasuhiro Funada, Yoshikazu Kotani, Masaru Yoshida, Yoshihiro Nishimura
XXI World Allergy Congress 2009年12月9日 Buenos Aires, República Argentina

Snail and slug-mediated epithelial mesenchymal transition in lung cancer cells
Daisuke Tamura Tokuzo Arao, Tomoyuki Nagai, Kazuyuki Furuta, Kazuko Sakai, Kanae Kudo, Hiroyasu Kaneda, Keiichi Aomatsu, Yoshihiko Fujita, Kazuko Matsumoto, Yoshikazu Kotani, Yoshihiro Nishimura, Nagahiro Saijo, Kazuto Nishio
101st American Association for Cancer Research annual meeting 2010年4月20日  Washington DC, USA

To develop the biomaker of lung cancer by the detection of metabolites expression pattern.
Suya Okamoto, Shin Nishiumi, Yukihisa Hatakeyama, Nobuko Hazeki, Yumiko Ishikawa, Kazuyuki Kobayashi, Masakazu Shinohara, Masaru Yosida, Yoshihiro Nishimura.
ATS 2010 International Conference, 2010年5月17日, New Orleans, USA

The role of FcRn in the allergic airway inflammation
Kyosuke Nakata, Kazuyuki Kobayashi, Yumiko Ishikawa, Suya Okamoto, Masatsugu Yamamoto, Yasuhiro Funada, Yoshikazu Kotani, Masaru Yoshida, Yoshihiro Nishimura
ATS 2010 International Conference, May 17, 2010 New Orleans, LA

The difference between intravenous and intratracheal delivery of sphingosine kinase inhibitor in asthmatic mice models
Yoshitaka Kawa, Teruaki Nishiuma, Kazuyuki Kobayashi, Yasuhiro Funada, Yoshikazu Kotani, Yoshihiro Nishimura
ATS 2010 International Conference, 2010年5月17日, New Orleans, USA

Therapeutic mechanism of intravenous IgG and inhibitory Fc receptor on CD11c+ dendritic cells in murine asthma model
Masatsugu Yamamoto, Kazuyuki Kobayashi, Yumiko Ishikawa, Kyosuke Nakata, Yasuhiro Funada, Yoshikazu Kotani, Yoshihiro Nishimura
2010 Korea-Japn Joint Allergy Symposium 2010年5月28日, Seoul, Korea

Visualization of variance of respiratory impedance in smokers and COPD
Masatsugu Yamamoto, Kazuyuki Kobayashi, Nobuko Hazeki, Emi Kuramoto, Yasuhiro Funada, Yoshikazu Kotani, Yoshihiro Nishimura
ERS 2010,2010年9月19日 Barcelona, Spain

Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1.
T. Nagano, M. Yasunaga, K. Goto, H. Kenmotsu, Y. Koga, J. Kuroda, Y. Nishimura, T. Sugino, Y. Nishiwaki, Y. Matsumura
2010 ASCO Annual Meeting, 2010年6月4日 Chicago, USA

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2009

Otera H, Ishida T, Nishiuma T, Kobayashi K, Kotani Y, Yasuda T, Kundu RK, Quertermous T, Hirata K, Nishimura Y.
Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration.
Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L594-602. Epub 2009 Jan 23.

Kuramoto E, Nishiuma T, Kobayashi K, Yamamoto M, Kono Y, Funada Y, Kotani Y, Sisson TH, Simon RH, Nishimura Y.
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
Am J Physiol Lung Cell Mol Physiol. 2009 Mar;296(3):L337-46. Epub 2008 Dec 19.

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2008

Maniwa Y, Yoshimura M, Takata M, Nishimura Y, Ohno Y.
Effective chemotherapy based on a chemosensitivity test for malignant pleural mesothelioma.
Ann Thorac Cardiovasc Surg. 2008 Oct;14(5):319-21.

Yamamoto M, Nishiuma T, Kobayashi K, Maniwa Y, Sakashita A, Funada Y, Kotani Y, Nishimura Y.
Rad9 is upregulated and plays protective roles in an acute lung injury model.
Biochem Biophys Res Commun. 2008 Nov 21;376(3):590-4. Epub 2008 Sep 20.

Sakashita A, Nishimura Y, Nogami M, Kuramoto E, Kono Y, Yamamoto M, Tamao N, Ohtera H, Kobayashi K, Funada Y, Nishiuma T, Kotani Y, Ohno Y.
Diffuse periairway thickening in patients with Mikulicz disease.
J Thorac Imaging. 2008 Aug;23(3):213-5.

Kuramoto E, Kinami S, Ishida Y, Shiotani H, Nishimura Y.
Continuous positive nasal airway pressure decreases levels of serum amyloid A and improves autonomic function in obstructive sleep apnea syndrome.
Int J Cardiol. 2008 Jun 25. [Epub ahead of print]

Ohno Y, Koyama H, Takenaka D, Nogami M, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K.
Dynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules.
J Magn Reson Imaging. 2008 Jun;27(6):1284-95.

Koyama H, Ohno Y, Kono A, Takenaka D, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K.
Quantitative and qualitative assessment of non-contrast-enhanced pulmonary MR imaging for management of pulmonary nodules in 161 subjects.
Eur Radiol. 2008 Oct;18(10):2120-31. Epub 2008 May 6.

Nishiuma T, Nishimura Y, Okada T, Kuramoto E, Kotani Y, Jahangeer S, Nakamura SI.
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.
Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1085-93. Epub 2008 Mar 21.

Ohno Y, Iwasawa T, Seo JB, Koyama H, Takahashi H, Oh YM, Nishimura Y, Sugimura K.
O2-enhanced MRI vs. CT: Multi-center Study for the Clinical Stage Classification of Smoking-related COPD.
Am J Respir Crit Care Med. 2008 May 15;177(10):1095-102. Epub 2008 Feb 14.

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2007

Kono Y, Nishiuma T, Nishimura Y, Kotani Y, Okada T, Nakamura S, Yokoyama M.
Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta1.
Am J Respir Cell Mol Biol. 2007;37(4):395-404.

Sakashita A, Nishimura Y, Nishiuma T, Takenaka K, Kobayashi K, Kotani Y, Yokoyama M.
Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.
Eur J Pharmacol. 2007;571(1):62-71.

Takeda T, Hattori N, Tokuhara T, Nishimura Y, Yokoyama M, Miyake M.
Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model.
Cancer Res. 2007;67(4): 1744-9.

Shimada T, Nishimura Y, Nishiuma T, Rikitake Y, Hirase T, Yokoyama M.
Adenoviral transfer of rho family proteins to lung cancer cells ameliorates cell proliferation and motility and increases apoptotic change.
Kobe J Med Sci. 2007;53(3):125-34.

Ohno Y, Koyama H, Takenaka D, Nogami M, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K.
Dynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules.
J Magn Reson Imaging. 2008 Jun;27(6):1284-95.

Ohno Y, Koyama H, Nogami M, Takenaka D, Yoshikawa T, Yoshimura M, Kotani Y, Nishimura Y, Higashino T, Sugimura K.
Whole-body MR imaging vs. FDG-PET: comparison of accuracy of M-stage diagnosis for lung cancer patients.
J Magn Reson Imaging. 2007;26(3):498-509.

Ohno Y, Koyama H, Takenaka D, Nogami M, Kotani Y, Nishimura Y, Yoshimura M, Yoshikawa T, Sugimura K.
Coregistered ventilation and perfusion SPECT using krypton-81m and Tc-99m-labeled macroaggregated albumin with multislice CT utility for prediction of postoperative lung function in non-small cell lung cancer patients.
Acad Radiol. 2007;14(7):830-8.

Takeda T, Nishimura Y, Tsuchiya T, Nakata K, Takenaka K, Nakata H, Yokoyama M.
A large abdominal wall mass as an initial manifestation of malignant mesothelioma.
Am J Med Sci. 2007;333(4):218-20.

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2006

Takenaka K, Nishimura Y, Nishiuma T, Sakashita A, Yamashita T, Kobayashi K, Satouchi M, Ishida T, Kawashima S, Yokoyama M.
Ventilator-induced lung injury is reduced in transgenic mice that overexpress endothelial nitric oxide synthase.
Am J Physiol Lung Cell Mol Physiol. 2006;290(6):L1078-86.

Kobayashi K, Nishimura Y, Shimada T, Yoshimura S, Funada Y, Satouchi M, Yokoyama M.
Effect of continuous positive airway pressure on soluble CD40 ligand in patients with obstructive sleep apnea syndrome.
Chest. 2006;129(3):632-7.

Kobayashi K, Nishimura Y, Yamashita T, Nishiuma T, Satouchi M, Yokoyama M.
The effect of overexpression of endothelial nitric oxide synthase on eosinophilic lung inflammation in a murine model.
Int Immunopharmacol. 2006;6(7):1040-52.

Yoshimura S, Nishimura Y, Nishiuma T, Yamashita T, Kobayashi K, Yokoyama M.
Overexpression of nitric oxide synthase by the endothelium attenuates bleomycin-induced lung fibrosis and impairs MMP-9/TIMP-1 balance.
Respirology. 2006;11(5):546-56.

Nakajima T, Nishimura Y, Nishiuma T, Kotani Y, Nakata H, Yokoyama M.
Cough sensitivity in pure cough variant asthma elicited using continuous capsaicin inhalation.
Allergol Int. 2006;55(2):149-55.

Maniwa Y, Yoshimura M, Bermudez VP, Okada K, Kanomata N, Ohbayashi C, Nishimura Y, Hayashi Y, Hurwitz J, Okita Y.
His239Arg SNP of HRAD9 is associated with lung adenocarcinoma.
Cancer. 2006;106(5):1117-22.

Takeda T, Nishimura Y, Satouchi M, Kamiryo H, Takenaka K, Kasai D, Urata Y, Kobayashi K, Shimada T, Yoshimura S, Nishiuma T, Yokoyama M.
Usefulness of the oximetry test for the diagnosis of sleep apnea syndrome in Japan.
Am J Med Sci. 2006;331(6):304-8.

Kitazawa R, Kitazawa S, Nishimura Y, Kondo T, Obayashi C.
Lung carcinosarcoma with liposarcoma element: autopsy case.
Pathol Int. 2006;56(8):449-52.

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2005

Nakajima T, Nishimura Y, Nishiuma T, Kotani Y, Funada Y, Nakata H, Yokoyama M.
Characteristics of patients with chronic cough who developed classic asthma during the course of cough variant asthma: a longitudinal study.
Respiration. 2005;72(6):606-11.

Urata Y, Nishimura Y, Hirase T, Yokoyama M.
Sphingosine 1-phosphate induces alpha-smooth muscle actin expression in lung fibroblasts via Rho-kinase.
Kobe J Med Sci. 2005;51(1-2):17-27.

Sakaeda T, Okamura N, Gotoh A, Shirakawa T, Terao S, Morioka M, Tokui K, Tanaka H, Nakamura T, Yagi M, Nishimura Y, Yokoyama M, Okumura K.
EGFR mRNA is upregulated, but somatic mutations of the gene are hardly found in renal cell carcinoma in Japanese patients.
Pharm Res. 2005;22(10):1757-61.

Higashino T, Ohno Y, Takenaka D, Watanabe H, Nogami M, Ohbayashi C, Yoshimura M, Satouchi M, Nishimura Y, Fujii M, Sugimura K.
Thin-section multiplanar reformats from multidetector-row CT data: utility for assessment of regional tumor extent in non-small cell lung cancer.
Eur J Radiol. 2005;56(1):48-55.

Ohno Y, Hatabu H, Higashino T, Nogami M, Takenaka D, Watanabe H, Van Cauteren M, Yoshimura M, Satouchi M, Nishimura Y, Sugimura K.
Oxygen-enhanced MR imaging: correlation with postsurgical lung function in patients with lung cancer.
Radiology. 2005;236(2):704-11.

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2004

Funada Y, Nishimura Y, Yokoyama M.
Imbalance of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 is associated with pulmonary emphysema in Klotho mice.
Kobe J Med Sci. 2004;50(3-4):59-67.

Ohno Y, Hatabu H, Takenaka D, Higashino T, Watanabe H, Ohbayashi C, Yoshimura M, Satouchi M, Nishimura Y, Sugimura K.
Metastases in mediastinal and hilar lymph nodes in patients with non-small cell lung cancer: quantitative and qualitative assessment with STIR turbo spin-echo MR imaging.
Radiology. 2004;231(3):872-9.

Ohno Y, Hatabu H, Higashino T, Takenaka D, Watanabe H, Nishimura Y, Yoshimura M, Sugimura K.
Dynamic perfusion MRI versus perfusion scintigraphy: prediction of postoperative lung function in patients with lung cancer.
AJR Am J Roentgenol. 2004;182(1):73-8.

Murakami Y, Kanazawa K, Okuno K, Maekawa S, Matsuda Y, Miyamoto Y, Nishimura Y, Kanomata N, Ohbayashi C, Hashimoto M, Akita H.
High-grade neuroendocrine carcinoma of the lung presenting an unusual spread mimicking pleural mesothelioma associated with dermatomyositis.
Am J Med Sci. 2004;327(4):227-30.

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2003

Tsuchiya T, Nishimura Y, Nishiuma T, Kotani Y, Funada Y, Yoshimura S, Yokoyama M.
Airway remodeling of murine chronic antigen exposure model.
J Asthma. 2003;40(8):935-44.

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