がん分野

• Endo, M., Tanaka, Y., Otsuka, M., Minami, Y. E2F1-Ror2 signaling mediates coordinated transcriptional regulation to promote G1/S phase transition in bFGF-stimulated NIH/3T3 fibroblasts. FASEB J., 34 (2): 3413-3428, 2020. doi: 10.1096/fj.201902849R.
• Miao, W., Sakai, K., Sato, H., Imamura, R., Jangphattananont, N., Takagi, J., Nishita, M., Minami, Y., Matsumoto, K. Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer. Cancer Sci. 110 (10): 3340-3349, 2019. doi: 10.1111/cas.14142
• Nagai, T., Ishikawa, T., Minami, Y., Nishita, M. Tactics of cancer invasion: solitary and collective invasion. J. Biochem. (review), 167 (4): 347-355, 2020. doi: 10.1093/jb/mvaa003.
• (国)Elberg, G, Liraz-Zaltsman, S, Reichert, F, Matozaki, T, Tal, M, Rotshenker, S. Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury. J Neuroinflammation, 16 (1): 277, 2019.
• (国)Komori, S, Saito, Y, Respatika, D, Nishimura, T, Kotani, T, Murata, Y, Matozaki, T. SIRPα+ dendritic cells promote the development of fibroblastic reticular cells in murine peripheral lymph nodes. Eur. J. Immunol, 49 (9): 1364-1371, 2019.
• Wang, B, Saito, Y, Nishimura, M, Ren, Z, Tjan, L.H, Refaat, A, Iida-Norita, R, Tsukamoto, R, Komatsu, M, Itoh, T, Matozaki, T, Mori, Y. An animal model that mimics human herpesvirus 6B pathogenesis. J. Virol,94 (6): pii: e01851-19, 2020.
• Kodama, T., Koma, Y.I., Arai, N., Kido, A., Urakawa, N., Nishio, M., Shigeoka, M., Yokozaki, H. CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Lab. Invest., 2020 (in press)　doi:10.1038/s41374-020-0441-4.
• Okamoto, M., Koma, Y.I., Kodama, T., Nishio, M., Shigeoka, M., Yokozaki, H. Growth Differentiation Factor 15 Promotes Progression of Esophageal Squamous Cell Carcinoma via TGF-β Type II Receptor Activation. 　 Pathobiology, 87(2): 100-113, 2020. doi: 10.1159/000504394.
• Shigeoka, M., Koma, Y.I., Nishio, M., Komori, T., Yokozaki, H. CD163+ macrophages infiltration correlates with the immunosuppressive cytokine interleukin 10 expression in tongue leukoplakia.　 Clin. Exp. Dent. Res., 5(6): 627-637, 2019. doi: 10.1002/cre2.228.
• Higashino N, Koma Y, Hosono M, Takase N, Okamoto M, Kodaira H, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H.Fibroblast activation protein-positive fibroblasts promote tumor progression through secretion of CCL2 andinterleukin-6 in esophageal squamous cell carcinoma. Lab Invest. 99(6):777-792,2019
• Kato W, Nishio M, To Y, Togashi H, Mak TW, Takada H, Ohga S, Maehama T, Suzuki A. MOB1 regulates thymocyte egress and T-cell survival in mice in a YAP1-independent manner. Genes Cells. 24(7), 485-495.2019
• Omori H, Nishio M, Masuda M, Miyachi Y, Ueda F, Nakano T, Sato K, Mimori K, Taguchi K, Hikasa H, Nishina H, Tashiro H, Kiyono T, Mak TW, Nakao K, Nakagawa T, Maehama T, Suzuki A. YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma. Sci Adv. 6(12), eaay3324.2020
• Aoki T, Nishita M, Sonoda J, Ikeda T, Kakeji Y, Minami Y. Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi-associated microtubules. Cancer Sci. 110(4):1306-1316,2019
• Ikeda T, Nishita M, Hoshi K, Honda T, Kakeji Y, Minami Y. Mesenchymal stem cell-derived CXCL16 promotes progression of gastric cancer cells by STAT3-mediated expression of Ror1. Cancer Sci., 111(4):1254-1265,2020
• Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D,Kakeji Y, Suzuki A, Dalerba P, Shimono Y. miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells. Cancer Res. 79(20):5151-5158,2019
• Masuda T, Baba K, Nomura T, Tsujita K, Murayama T, Itoh T, Takatani-Nakase T, Sokabe M, Inagaki N, Futaki S. An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling. Commun Biol. 2: 243. 2019
• Hasegawa J, Jebri I, Yamamoto H, Tsujita K, Tokuda E, Shibata H, Maki M, Itoh T. SH3YL1 cooperates with ESCRT-I in the sorting and degradation of the EGF receptor. J. Cell Sci. 132(19):jcs229179. 2019

代謝分野

• Amin HZ, Sasaki N, Yamashita T, Mizoguchi T, Hayashi T, Emoto T, Matsumoto T, Yoshida N, Tabata T, Horibe S, Kawauchi S, Rikitake Y, Hirata K. CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice. Sci Rep. 2019 ;9(1):8065.
• Barinda AJ, Ikeda K, Nugroho DB, Wardhana DA, Sasaki N, Honda S, Urata R,Matoba S, Hirata K, Emoto N. Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype. Nat Commun. 2020 ;11(1):481.
• Morita Y, Nogami M, Sakaguchi K, Okada Y, Hirota Y, Sugawara K, Tamori Y, Zeng F, Murakami T, Ogawa W. Enhanced Release of Glucose into the Intraluminal Space of the Intestine Associated with Metformin Treatment as Revealed by [18F]Fluorodeoxyglucose PET-MRI. Diabetes Care 2020; 43(8): 1796-1802
• Sugawara K, Nomura K, Okada Y, Sugano A, Matsumoto M, Takarada T, Takeuchi A, Awano H, Hirota Y, Nishio H, Takaoka Y, Ogawa W. In silico and in vitro analyses of the pathological relevance of the R258H mutation of hepatocyte nuclear factor 4α identified in maturity-onset diabetes of the young type 1. J Diabetes Investig. 10(3):680-684, 2019
• Hosooka T, Hosokawa Y, Matsugi K,Shinohara M, Senga Y, Tamori Y, Aoki C, Matsui S, Sasaki T, Kitamura T, Kuroda M, Sakaue H, Nomura K, Yoshino K, Nabatame Y, Itoh Y, Yamaguchi K, Hayashi Y, Nakae J, Accili D, Yokomizo T, Seino S, Kasuga M, Ogawa W. The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase- leukotriene B4 axis. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11674-11684.
• Yamamoto M, Iguchi G, Bando H, Kanie K, Hidaka-Takeno R, Fukuoka H, Takahashi Y. Automimmune pituitary disease-New concepts with clinical implications. Endocri Rev 2020 41 1-12 doi: 10.1210/endrev/bnz003.
• Suda K, Fukuoka H, Yamazaki Y, Shigemura K, Mukai M, Odake Y, Matsumoto R, Bnado H, Takahashi M, Iguchi G, Fujisawa M, Oka M, Ono Katsuhiko, Chihara K, Sasano H, Ogawa W, Takahashi Y. Cardiac myxoma caused by fumarate hydratase gene deletion in patients with cortisol-secreting adrenocortical adenoma. J Clin Endocrinol Metab. 2020 105, dgaa163
• Inoue H, Saito M, Kouchi K, Asahara S, Nakamura F, Kido Y. Association between mean platelet volume in the pathogenesis of type 2 diabetes mellitus and diabetic macrovascular complications in Japanese patients J. Diab. Invest. in press
• Katsuyama A, Kusuhara S, Asahara S, Nakai S, Mori S, Matsumiya W, Miki A, Kurimoto T, Imai H, Kido Y, Ogawa W, Nakamura M. En face slab optical coherence tomography imaging successfully monitors progressive degenerative changes in the innermost layer of the diabect retina. BMJ Open Diabetes Research & Care. 8:e001120,2020
• Kanno A, Asahara S, Furubayashi A, Masuda K, Yoshitomi R, Subuki E, Takai T, Koyanagi-Kimura M, Matsuda T, Bartolome A, Hirota Y, Yokoi N, Inaba Y, Inoue H, Matsumoto M, Inoue K, Abe T, Wei F, Tomizawa K,Ogawa W, Seino S, Kasuga M, Kido Y. GCN2 regulates pancreatic β-cell mass by sensing intracellular amino acid levels. JCI Insight. 5(9):e128820,2020

脳こころ分野

• (国)Takumi, T., Tamada, K., Hatanaka, F., Nakai, N., Bolton, P.F. Behavioral neuroscience of autism. Neurosci Biobehav Rev. 110:60-76, 2020.
• (国)Tsurugizawa, T., Tamada, K., Ono, N., Karakawa, S., Kodama, Y., Debacker, C., Hata, J., Okano, H., Kitamura, A., Zalesky, A., Takumi, T. Awake functional MRI detects neural circuit dysfunction in a mouse model of autism. Science Adv. 6:eaav4520, 2020.
• Furumai, R., Tamada, K., Liu, X., Takumi, T. UBE3A regulates the transcription of IRF, an antiviral immunity. Hum Mol Genet. 28:1947-1958, 2019.
• Nie X, Kitaoka S, Shinohara M, Kakizuka A, Narumiya S, Furuyashiki T. Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E2 synthesis in the brain and their behavioral relevance. Sci Rep 9, 17548, 2019.
• (国)Numa C, Nagai H, Taniguchi M, Nagai M, Shinohara R, Furuyashiki T. Social defeat stress-induced increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex. Sci Rep 9, 16670, 2019.
• Ano Y, Kita M, Kitaoka S, Furuyashiki T. Leucine-histidine dipeptide attenuates microglial activation and emotional disturbances induced by brain inflammation and repeated social defeat stress. Nutrients 11, 2161, 2019.
• (国)Nakae T, Matsumoto R, Kunieda T, Arakawa Y, Kobayashi K, Shimotake A, Yamao Y, Kikuchi T, Aso T, Matsuhashi M, Yoshida K, Ikeda A, Takahashi R, Lambon Ralph MA, Miyamoto S. Connectivity Gradient in the Human Left Inferior Frontal Gyrus: Intraoperative Cortico-Cortical Evoked Potential Study. Cereb Cortex, 30:4633-4650, 2020, https://doi.org/10.1093/cercor/bhaa065
• (国)Seo JH, Tsuda I, Lee YJ, Ikeda A, Matsuhashi M, Matsumoto R, Kikuchi T, Kang H. Pattern Recognition in Epileptic EEG Signals via Dynamic Mode Decomposition. Mathematics 2020, 8, 481. https://doi.org/10.3390/math8040481
• Nakatani M, Matsumoto R, Kobayashi K, Hitomi T, Inouchi M, Matsuhashi M, Kinoshita M, Kikuchi T, Yoshida K, Kunieda T, Miyamoto S, Takahashi R, Hattori N, Ikeda A. Electrical Cortical Stimulations Modulate Spike and Post-Spike Slow-Related High-Frequency Activities in Human Epileptic Foci. Clin Neurophysiol, 131:1741-1754, 2020, doi: 10.1016/j.clinph.2020.03.042
• Haruwaka K, Ikegami A, Tachibana Y, Ohno N, Konishi H, Hashimoto A, Matsumoto M, Kato D, Ono R, Kiyama H, Moorhouse AJ, Nabekura J and Wake H*. Dual Microglia Effects on Blood Brain Barrier Permeability Induced by Systemic Inflammation, Nature Commun. 2019, Dec 20;10(1):5816. Doi: 10. 1038/s41467-019-13812-z.
• Kato D, Wake H*, Lee PR, Tachibana Y, Ono R, Sugio S, Tsuji Y, Tanaka HY, Tanaka RY, Masamizu Y, Hira R, Moorhouse AJ, Tamamaki N, Ikenaka K, Matsukawa N, Fields RD, Nabekura J, and Matsuzaki M. Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity. Glia , 2020, Jan;68(1):193-210.
• Tsuji T, Ozasa H, Aoki W, Aburaya S, Yamamoto Funazo T, Furugaki K, Yoshimura Y, Yamazoe M, Ajjimizu H, Yasuda Y, Nomizo T, Yoshida H, Sakamori Y, Wake H, Ueda M, Kim YH, Hirai T. YAP1 mediates survival of ALK-rearrahged lung cancer cells treated with alectinib via pro-apoptotic protein regulation. Nature Commun. 2020 Jan 3;11(1):74. Doi: 10.1038/s41467-019-13771-5

免疫・炎症分野

• Nagamata S, Aoshi T, Kawabata A, Yamagishi Y, Nishimura M, Kuwabara S, Murakami K, Yamada H, Mori Y. Identification of CD4 and H-2Kd-restricted cytotoxic T lymphocyte epitopes on the human herpesvirus 6B glycoprotein Q1 protein. Sci Rep. 9(1): 3911. 2019. doi: 10.1038/s41598-019-40372-5.
• Wang B, Nishimura M, Maekawa Y, Kotari T, Okuno T, Mori Y. Humanization of Murine Neutralizing Antibodies against Human Herpesvirus 6B. J Virol. 93(10): e02270-18. 2019. doi: 10.1128/JVI.02270-18.
• (国)Athiyyah, AF., Utsumi, T., Wahyuni, RM., Dinana, Z., Yamani, LN., Soetjipto., Sudarmo, SM., Ranuh, RG., Darma, A., Juniastuti., Raharjo, D., Matsui, C., Deng, L., Abe, T., Doan, YH., Fujii, Y., Shimizu, H., Katayama, K., Lusida, MI., Shoji, I. Molecular epidemiology and clinical features of rotavirus infection among pediatric patients in East Java, Indonesia during 2015-2018: dynamic changes in rotavirus genotypes from equine-like G3 to typical human G1/G3, Frontiers in Microbiology, 10: 940, 2019. doi: 10.3389/fmicb.2019.00940.
• (国)Gunawan, E., Utsumi, T., Wahyuni, RM., Dinana, Z., Sudarmo, SM., Shoji, I., Soetjipto. Post-vaccinated asymptomatic rotavirus infections: A community profile study of children in Surabaya, Indonesia. Journal of Infection and Public Health, 12: 625-629, 2019. doi: 10.1016/j. jiph.2019.02.015.
• Jimbo, H., Nagai, H., Fujiwara, S., Shimoura, N., Nishigori, C. Fas-FasL interaction in cytotoxic T cell-mediated vitiligo: The role of lesional expression of tumor necrosis factor-α and interferon-γ in Fas-mediated melanocyte apoptosis. Exp Dermatol, 29(1): 61-70, 2020. doi: 10.1111/exd.14053.
• Nagai, H., Nishigori, C. Image Gallery: Antihelix red-violaceous macules in juvenile dermatomyositis associated with antimelanoma differentiation-associated protein 5 antibody. Br J Dermatol, 182(3): e85, 2020. doi: 10.1111/bjd.18530.
• Oda, Y., Fukunaga, A., Washio, K., Imamura, S., Hatakeyama, M., Ogura, K., Nishigori, C. Low Responsiveness of Basophils via FcεRI Reflects Disease Activity in Chronic Spontaneous Urticaria. J Allergy Clin Immunol Pract, 7(8) :2835-2844.e7, 2019. doi: 10.1016/j .jaip.2019.05.020.
• Sendo S, Saegusa J, Yamada H, Nishimura K, Morinobu A.　Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice. Arthritis Res Ther. 2019 Aug 6;21(1):184.
• Takahashi S, Saegusa J, Onishi A, Morinobu A. Biomarkers identified by serum metabolomic analysis to predict biologic treatment response in rheumatoid arthritis patients. Rheumatology (Oxford). 2019 May 29
• Ueda Y, Saegusa J, Okano T, Sendo S, Yamada H, Nishimura K, Morinobu A. Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice. Sci Rep. 2019 Apr 23;9(1):6374.
• Hashimoto, S., Furukawa, S., Hashimoto, A., Tsutaho, A., Fukao, A., Sakamura, Y., Parajuli, G., Onodera,Y., Otsuka, Y., Handa, H., Oikawa, T., Hata, S., Nishikawa, Y., Mizukami, Y., Kodama, Y., Murakami, M., Fujiwara, T., Hirano, S., Sabe, H. ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer. Proc Natl Acad Sci U S A,116(35):17450-17459, 2019. doi: 10.1073/pnas.1901765116.
• Nishikawa, Y., Kodama, Y., Shiokawa, M., Matsumori, T., Marui, S., Kuriyama, K., Kuwada, T., Sogabe, Y., Kakiuchi, N., Tomono, T., Mima, A., Morita, T., Ueda, T., Tsuda, M., Yamauchi, Y., Sakuma, Y., Ota, Y., Maruno, T., Uza, N., Uesugi, M., Kageyama, R., Chiba, T., Seno, H. Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis. Oncogene, 38(22):4283-4296. 2019. doi: 10.1038/s41388-019-0718-5.
• Sawada, R., Maehara, R., Oshikiri, T., Nakamura, T., Itoh, T., Kodama, Y., Kakeji, Y., Zen, Y. MDM2 copy number increase: A poor prognostic, molecular event in esophageal squamous cell carcinoma. Hum Pathol, 89:1-9, 2019. doi: 10.1016/j.humpath.2019.04.002.
• (国) Oka, T., Negi, B. S., Ueda, S., Sasaki, M., Kotaki, T., Kameoka, M. Genotypic Characterization of HIV-1 Subtype C in the Central Region of Nepal. AIDS Res. Hum. Retroviruses, 35(9):870-875, 2019. doi: 10.1089/AID.2019.0105.
• (国) Ueda, S., Witaningrum, A. M., Khairunisa, S. Q., Kotaki, T., Motomura, K., Nasronudin, Kameoka, M. Transmission dynamics of HIV-1 subtype B strains in Indonesia. Sci. Rep., 9(1): 13986, 2019. doi: 10.1038/s41598-019-50491-8.

創薬・医療機器分野

• Komatsu S, Terashima K, Matsuo Y, Takahashi D, Suga M, Nishimura N, Lee D, Tai K, Kido M, Toyama H, Demizu Y, Tokumaru S, Okimoto T, Sasaki R, Fukumoto T. Validation of combination treatment with surgical spacer placement and subsequent particle radiotherapy for unresectable hepatocellular carcinoma. J Surg Oncol. 2019 Aug;120(2):214-222. doi: 10.1002/jso.25495. Epub 2019 May 10.
• Sasaki R, Demizu Y, Yamashita T, Komatsu S, Akasaka H, Miyawaki D, Yoshida K, Wang T, Okimoto T, Fukumoto T. First-In-Human Phase 1 Study of a Nonwoven Fabric Bioabsorbable Spacer for Particle Therapy: Space-Making Particle Therapy (SMPT). Adv Radiat Oncol. 2019 May 15;4(4):729-737
• Urade T, Yoshida T, Ikeo N, Naka K, Kido M, Toyama H, Ueno K, Tanaka M, Mukai T, Fukumoto T. Novel biodegradable magnesium alloy clips compared with titanium clips for hepatectomy in a rat model. BMC Surg. 2019 Sep 9;19(1):130. doi: 10.1186/s12893-019-0600-y.
• (国)Gerds, A.T., Tauchi, T., Ritchie, E., Deininger, M., Jamieson, C., Mesa, R., Heaney, M., Komatsu, N., Minami, H., Su, Y., Naveed, Shaik M., Zhang, X., DiRienzo, C., Zeremski, M., Chan, G., Talpaz, M. Phase 1/2 trial of glasdegib in patients with primary or secondary myelofibrosis previously treated with ruxolitinib. Leukemia Res 79: 38-44, 2019. doi: 10.1016/j.leukres.2019.02.012.
• (国)Hughes, T.P., Mauro, M.J., Cortes, J.E., Minami, H., Rea, D., DeAngelo, D.J., Breccia, M., Goh, Y.-T., Talpaz, M., Hochhaus, A., le Coutre, P., Ottmann, O., Heinrich, M.C., Steegmann, J.L., Deininger, M.W.N., Janssen, J.J.W.M., Mahon, F.-.X., Minami, Y., Yeung, D., Ross, D.M., Tallman, M.S., Park, J.H., Druker, B.J., Hynds, D., Duan, R., Meille, C., Hourcade-Potelleret, F., Vanasse. K.G., Lang F, Kim, D.-W. Asciminib in tyrosine kinase inhibitor–resistant and –intolerant chronic myeloid leukemia. New Engl J Med 381: 2315-2326, 2019. doi: 10.1056/NEJMoa1902328.
• (国)Toyoda, M., Watanabe, K., Amagasaki, T., Natsume, K., Takeuchi, H., Quadt, C., Shirao, K., Minami H. A Phase I study of single-agent BEZ235 special delivery system sachet in Japanese patients with advanced solid tumors. Cancer Chemother Pharmacol 83: 289-299, 2019. doi.org/10.1007/s00280-018-3725-2.
• Minami, H., Fujiwara, Y., Muro, K., Sato, M., Moriya, A. Phase I study of BGT226, a pan-PI3K and mTOR inhibitor, in Japanese patients with advanced solid cancers. Cancer Chemother Pharmacol 84(4):337-343, 2019. doi.org/10.1007/s00280-019-03883-6.
• Horinouchi, T., Nozu, K., Yamamura, T., Minamikawa, S., Nagano, C., Sakakibara, N., Nakanishi, K., Shima, Y., Morisada, N., Ishiko, S., Aoto, Y., Nagase, H., Takeda, H., Rossanti, R., Kaito, H., Matsuo, M., Iijima, K.　Determination of the pathogenicity of known COL4A5 intronic variants by in vitro splicing assay. Sci Rep, 9(1):12696, 2019. doi: 10.1038/s41598-019-48990-9.
• Nagano, C., Yamamura, T., Horinouchi, T., Aoto, Y., Ishiko, S., Sakakibara, N., Shima, Y., Nakanishi, K., Nagase, H., Iijima, K., Nozu, K. Comprehensive genetic diagnosis of Japanese patients with severe proteinuria. Sci Rep, 10(1):270, 2020. doi: 10.1038/s41598-019-57149-5.
• Rossanti, R., Shono, A., Miura, K., Hattori, M., Yamamura, T., Nakanishi, K., Minamikawa, S., Fujimura, J., Horinouchi, T., Nagano, C., Sakakibara, N., Kaito, H., Nagase, H., Morisada, N., Asanuma, K., Matsuo, M., Nozu, K., Iijima. K. Molecular assay for an intronic variant in NUP93 that causes steroid resistant nephrotic syndrome. J Hum Genet, 64(7):673-679, 2019. doi: 10.1038/s10038-019-0606-4
• Inoue T, Yamamichi F, Endo T, Kaku Y, Horikoshi M, Hara S, Fujisawa M. Successful percutaneous flexible ureteroscopy for treatment of distal ureteral stones under modified Valdivia position after Cohen reimplantation. IJU Case Rep. 2019 May 8;2(5):245-248.
• Furukawa J, Kanayama H, Azuma H, Inoue K, Kobayashi Y, Kashiwagi A, Segawa T, Takahashi Y, Horie S, Ogawa O, Takenaka A, Shiroki R, Tanabe K, Fujisawa M. 'Trifecta' outcomes of robot-assisted partial nephrectomy: a large Japanese multicenter study. Int J Clin Oncol. 2020 Feb;25(2):347-353.
• Hinata N, Bando Y, Chiba K, Furukawa J, Harada K, Ishimura T, Nakano Y, Fujisawa M. Application of hyaluronic acid/carboxymethyl cellulose membrane for early continence after nerve-sparing robot-assisted radical prostatectomy. BMC Urol. 2019 Apr 23;19(1):25.
• Shigemura K, Kitagawa K, Chen KC, Sung SY, Fujisawa M. Effect of Preoperative Dutasteride on Holmium Laser Enucleation of the Prostate. Urol Int. 2020;104(5-6):356-360.

再生医学分野

• Suzuki K, Koyanagi-Aoi M, Uehara K, Hinata N, Fujisawa M, Aoi T. Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium. Sci Rep. 2019, 9(1):10506. doi: 10.1038/s41598-019-46848-8
• Matsumoto R, Suga H, Aoi T, Bando H, Fukuoka H, Iguchi G, Narumi S, Hasegawa T, Muguruma K, Ogawa W, Takahashi Y. Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells. J Clin Invest. 2020 130, 641-654. doi: 10.1172/JCI127378.
• Restu WK, Yamamoto S, Nishida Y, Ienaga H, Aoi T, Maruyama T, Hydrogel formation by short D-peptide for cell-culture scaffolds Mater Sci Eng C Mater Biol Appl. 2020, 111:110746. doi: 10.1016/j.msec.2020.110746
• Nakatani, T., Iwasaki, M., Yamamichi, A., Yoshioka, Y., Uesaka, T., Bitoh, Y., Maeda, K., Fukumoto, T., Takemoto, T., Enomoto, H., Point mutagenesis in mouse reveals contrasting pathogenetic effects between MEN2B‐ and Hirschsprung disease‐associated missense mutations of the RET gene. Dev Growth Differ, 62(4):214-222, 2020. doi: 10.1111/dgd.12664.
• Fujii H, Watanabe K, Kono K, Goto S, Watanabe S, Nishi S. Changes in serum and intracardiac fibroblast growth factor 23 during the progression of left ventricular hypertrophy in hypertensive model rats. Clin Exp Nephrol, 23(5):589-596, 2019. doi: 10.1007/s10157-018-1680-1.
• Goto K, Goto S, Fujii H, Watanabe K, Kono K, Nishi S. Effects of lanthanum carbonate on bone markers and bone mineral density in incident hemodialysis patients. J Bone Miner Metab. 37(6):1075-1082doi: 10.1007/s00774-019-01018-8.