Takeda M, Shimokawa M, Nakamura A, Nosaki K, Watanabe Y, Kato T, Hayakawa D, Tanaka H, Takahashi T, Oki M, Tachihara M, Fujimoto D, Hayashi H, Yamaguchi K, Yamamoto S, Iwama E, Azuma K, Hasegawa K, Yamamoto N, Nakagawa K. A phase II study (WJOG12819L) to assess the efficacy of osimertinib in patients with EGFR mutation-positive NSCLC in whom systemic disease (T790M-negative) progressed after treatment with first- or second-generation EGFR TKIs and platinum-based chemotherapy. Lung Cancer. 2023 177:44-50.

Tanda M, Yamamoto K, Hori T, Nishiguchi H, Yagi M, Shimizu M, Konishi T, Ozaki T, Yoshioka N, Tachihara M, Ito T, Ikushima S, Omura T, Yano I. Association of STAT3, CYP3A5, and ABCG2 Polymorphisms With Osimertinib-induced Adverse Events in NSCLC Patients. Anticancer Res. 2023 43:1775-1783.

Okamoto T, Murata Y, Hasegawa D, Yoshida M, Tanaka D, Ueda T, Hazama D, Oduori OS, Komori S, Takai T, Saito Y, Kotani T, Kosaka Y, Maniwa Y, Matozaki T.Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis.Cancer Sci. 2023 Feb 14. doi: 10.1111/cas.15758. Online ahead of print.

（書籍）特集Ⅱ　本邦におけるCOVID-19ワクチン　BNT162b2 mRNA COVID-19ワクチン後のSARS-CoV-2変異株に対する中和抗体応答
古川皓一
臨床免疫・アレルギー科　第79巻第1号（通巻631号）　科学評論社　2023年1月25日発行

（書籍）過敏性肺炎
西村善博
今日の治療指針2023　福井崇文次矢、高木誠、小室一成編　医学書院　314-315, 2023

Yasuda Y, Nagano T, Jimbo N, Kiriu T, Suraya R, Hazama D, Yamamoto M, Maniwa Y, Nishimura Y, Kobayashi K. Chloride Intracellular Channel 1 Expression Is Associated With Poor Prognosis of Lung Adenocarcinoma. Anticancer Res. 2022; 42:271-277.

Nakajima T, Nagano T, Nishiuma T, Nakata K, Nishimura Y. Usefulness Analysis of Fraction of Exhaled Nitric Oxide for the Differential Diagnosis of Acute Cough. In Vivo. 2022; 36:446-449.

Yumura M, Nagano T, Jimbo N, Dokuni R, Kiriu T, Tanaka Y, Tachihara M, Itoh T, Maniwa Y, Nishimura Y, Kobayashi K. Annexin A10 Expression as a Novel Prognostic Marker in Lung Adenocarcinoma. Anticancer Res. 2022 42:1289-1294.

Otoshi T, Nagano T, Park J, Hosomi K, Yamashita T, Tachihara M, Tabata T, Sekiya R, Tanaka Y, Kobayashi K, Mizuguchi K, Itoh T, Maniwa Y, Kunisawa J, Nishimura Y. The Gut Microbiome as a Biomarker of Cancer Progression Among Female Never-smokers With Lung Adenocarcinoma. Anticancer Res. 2022 42:1589-1598

Nakajima T, Nagano T, Nishimura Y. Retrospective Analysis of the Starting Dose of Combined ICS/LABA for Cough-variant Asthma and Cough-predominant Asthma. In Vivo. 2022 36:949-953

Fukui T, Tachihara M, Nagano T, Kobayashi K. Review of Therapeutic Strategies for Anaplastic Lymphoma Kinase-Rearranged Non-Small Cell Lung Cancer. Cancers (Basel). 2022 14:1184

Oizumi S, Takamura K, Harada T, Tachihara M, Morikawa N, Honda R, Watanabe S, Asao T, Kunisaki M, Fukuhara T, Noro R, Kikuchi E, Tsutani Y, Tenma T, Kobayashi K, Dosaka-Akita H; North East Japan Study Group, Hokkaido Lung Cancer Clinical Study Group. Phase II study of carboplatin-paclitaxel alone or with bevacizumab in advanced sarcomatoid carcinoma of the lung: HOT1201/NEJ024Int J Clin Oncol. 2022 27:676-683.

Kurahashi Y, Sutandhio S, Furukawa, Tjan LH, Iwata S, Sano S, Tohma Y, Ohkita H, Nakamura S, Nishimura M, Arii J, Kiriu T, Yamamoto M, Nagano T, Nishimura Y, Mori Y. Cross-Neutralizing Breadth and Longevity Against SARS-CoV-2 Variants After Infections. Front Immunol. 2022 Feb 24;13:773652.

Sakamoto M, Murata Y, Tanaka D, Kakuchi Y, Okamoto T, Hazama D, Saito Y, Kotani T, Ohnishi H, Miyasaka M, Fujisawa M, Matozaki T., Anticancer efficacy of monotherapy with antibodies to SIRPα/SIRPβ1 mediated by induction of antitumorigenic macrophages. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2109923118.

Kurahashi Y, Furukawa K, Sutandhio S, Tjan LH, Iwata S, Sano S, Tohma Y, Ohkita H, Nakamura S, Nishimura M, Arii J, Kiriu T, Yamamoto M, Nagano T, Nishimura Y, Mori Y. Cross-neutralizing activity against Omicron could be obtained in SARS-CoV-2 convalescent patients who received two doses of mRNA vaccination. J Infect Dis. 2022 May 5:jiac178. doi: 10.1093/infdis/jiac178.

Katsurada M, Tachihara M, Katsurada N, Takata N, Sato H, Mimura C, Yoshioka J, Furukawa K, Yumura M, Otoshi T, Yasuda Y, Kiriu T, Hazama D, Nagano T, Yamamoto M, Nishimura Y, Kobayashi K. Randomized single-blind comparative study of the midazolam/pethidine combination and midazolam alone during bronchoscopy. BMC Cancer. 2022 22:539.

Suprapto RP, Suzuki Y, Nagano T, Hirata KI, Emoto N. The loss of endothelin-2 exhibits an anticancer effect in A549 human lung adenocarcinoma cell line. Can J Physiol Pharmacol. 2022 Jun 9. doi: 10.1139/cjpp-2022-0006.

Zhao Y, Wang Q, Zhang L, Shi J, Wang Z, Cheng Y, He J, Shi Y, Chen W, Luo Y, Wu L, Wang X, Nan K, Jin F, Dong J, Li B, Yamaguchi F, Breadner D, Nagano T, Tanaka F, Husain H, Li K, Han B. The efficacy of anlotinib as third-line treatment for non-small cell lung cancer by EGFR mutation status: a subgroup analysis of the ALTER0303 randomized phase 3 study. Transl Lung Cancer Res. 2022 11:776-785.

Suraya R, Nagano T, Ryanto GRT, Effendi WI, Hazama D, Katsurada N, Yamamoto M, Tachihara M, Emoto N, Nishimura Y, Kobayashi K. Budesonide/glycopyrronium/formoterol fumarate triple therapy prevents pulmonary hypertension in a COPD mouse model via NFκB inactivation. Respir Res. 2022 23: 173.

Bao M, Huang Y, Lang Z, Zhao H, Saito Y, Nagano T, Kawagoe I, Divisi D, Hu X, Jiang G. Proteomic analysis of plasma exosomes in patients with non-small cell lung cancer. Transl Lung Cancer Res. 2022 11:1434-1452.

Nakajima T, Nagano T, Miyata Y, Murakami S, Mitsuyuki S, Funakoshi Y, Yakushijin K, Horimoto H, Nishimura Y, Kobayashi K. Inhaled corticosteroids do not affect the antibody titer against the SARS-CoV-2 spike protein in BNT162b2 mRNA vaccinated patients. Allergy Asthma Clin Immunol. 2022 18:78.

Fukui T, Tachihara M, Nagano T, Kobayashi K. Review of Therapeutic Strategies for Anaplastic Lymphoma Kinase-Rearranged Non-Small Cell Lung Cancer. Cancers (Basel). 2022 14:1184

Effendi WI, Nagano T. Connective Tissue Growth Factor in Idiopathic Pulmonary Fibrosis: Breaking the Bridge. Int J Mol Sci. 2022 23:6064

Suraya R, Tachihara M, Nagano T, Nishimura Y, Kobayashi K. Immunotherapy in Advanced Non-Small Cell Lung Cancers: Current Status and Updates. Cancer Manag Res. 2022 14:2079-2090.

Nagano T, Tachihara M, Tanaka Y. Future prospects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and surgery for non-small cell lung cancer. J Thorac Dis. 2022 14:809-811.

Tjan LH, Furukawa K, Kurahashi Y, Sutandhio S, Nishimura M, Arii J, Mori Y. Induction of High Neutralizing Activity Against Both Omicron BA.2 and Omicron BA.1 by Coronavirus Disease 2019 Messenger RNA Booster Vaccination. J Infect Dis. 2022 Apr 28;jiac159

Furukawa K, Tjan LH, Kurahashi Y, Sutandhio S, Nishimura M, Arii J, Mori Y. Assessment of neutralizing antibody response against SARS-CoV-2 variants after 2 to 3 doses of the BNT162b2 mRNA COVID-19 vaccine.
JAMA Network Open. 2022 May 2;5(5):e2210780

Ren Z, Nishimura M, Tjan LH, Furukawa K, Kurahashi Y, Sutandhio S, Aoki K, Hasegawa N, Arii J, Uto K, Matsui K, Sato I, Saegusa J, Godai N, Takeshita K, Yamamoto M, Nagashima T, Mori Y. Large-scale serosurveillance of COVID-19 in Japan: Acquisition of neutralizing antibodies for Delta but not for Omicron and requirement of booster vaccination to overcome the Omicron’s outbreak. PLoS One. 2022 Apr 5;17(4):e0266270

Kurahashi Y, Furukawa K, Sutandhio S, Tjan LH, Iwata S, Sano S, Tohma Y, Ohkita H, Nakamura S, Nishimura M, Arii J, Kiriu T, Yamamoto M, Nagano T, Nishimura Y, Mori Y. Cross-neutralizing activity against Omicron could be obtained in SARS-CoV-2 convalescent patients who received two doses of mRNA vaccination. J Infect Dis. 2022 May 5;jiac178

Furukawa K, Kurahashi Y, Ishimaru H, Nishimura M, Arii J, Sano S, Tohma Y, Ohkita H, Nakamura S, Iwata S, Mori Y. The number of COVID-19 vaccine doses and severe clinical outcomes in older patients infected with a SARS-CoV-2 Omicron variant. J Infect Dis. 2022 Sep 26;jiac395

Takemura T, Kataoka Y, Ashi N, Shirakawa C, Okazaki K, Sakurai A, Imakita T, Ikegaki S, Matsumoto H, Saito E, Takata H, Kaku S, Wada N, Shinomiya M, Otoshi T, Shimada M, Nikaido J, Iki R, Hirano K, Hirai T, Endo K, Hirabayashi M, Naganuma T. Influence of social isolation and loneliness on the prognosis of advanced lung cancer patients: a prospective cohort study. Support Care Cancer. 2022 Jul;30:6045-6053

Ishimaru H, Nishimura M, Tjan LH, Sutandhio S, Marini MI, Effendi GB, Shigematsu H, Kato K, Hasegawa N, Aoki K, Kurahashi Y, Furukawa K, Shinohara M, Nakamura T, Arii J, Nagano T, Nakamura S, Sano S, Iwata S, Mori Y.Novel monoclonal antibodies showing broad neutralizing activity for SARS-CoV-2 variants including Omicrons BA.5 and BA.2.75. bioRxiv (preprint) doi: https://doi.org/10.1101/2022.09.02.506305

Hayashi H, Sugawara S, Fukuda Y, Fujimoto D, Miura S, Ota K, Ozawa Y, Hara S, Tanizaki J, Azuma K, Omori S, Tachihara M, Nishino K, Bessho A, Chiba Y, Haratani K, Sakai K, Nishio K, Yamamoto N, Nakagawa K. A Randomized Phase II Study Comparing Nivolumab with Carboplatin-Pemetrexed for EGFR-Mutated NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors (WJOG8515L). Clin Cancer Res. 2022 28:893-902.

Nishikubo M, Jimbo N, Tanaka Y, Tachihara M, Itoh T, Maniwa Y. Sarcomatoid mesothelioma originating from mesothelioma in situ: are methylthioadenosine phosphorylase loss and CDKN2A homozygous deletion poor prognostic factors for preinvasive mesothelioma? Virchows Arch. 2022 481:307-312.

Hayashi H, Yonesaka K, Nakamura A, Fujimoto D, Azuma K, Sakata S, Tachihara M, Ikeda S, Yokoyama T, Hataji O, Yano Y, Hirano K, Daga H, Okada H, Chiba Y, Sakai K, Nishio K, Yamamoto N, Nakagawa K. Alternating therapy with osimertinib and afatinib for treatment-naive patients with EGFR-mutated advanced non-small cell lung cancer: A single-group, open-label phase 2 trial (WJOG10818L) Lung Cancer. 2022 168:38-45.

Shimizu N, Tanaka Y, Tachihara M, Maniwa Y. ROS1-Rearranged Lung Cancer Successfully Resected after Response to Crizotinib: A Case Report. Kobe J Med Sci. 2022 67:E143-E145.

Bao M, Huang Y, Lang Z, Zhao H, Saito Y, Nagano T, Kawagoe I, Divisi D, Hu X, Jiang G. Proteomic analysis of plasma exosomes in patients with non-small cell lung cancer. Transl Lung Cancer Res. 2022 Jul;11:1434-1452.

Nakajima T, Nagano T, Miyata Y, Murakami S, Mitsuyuki S, Funakoshi Y, Yakushijin K, Horimoto H, Nishimura Y, Kobayashi K. Inhaled corticosteroids do not affect the antibody titer against the SARS-CoV-2 spike protein in BNT162b2 mRNA vaccinated patients. Allergy Asthma Clin Immunol. 2022 Aug 25;18:78.

Katsurada N, Nagano T, Yamamoto M, Kiriu T, Dokuni R, Kamiryo H, Yoshioka A, Fukunaga A, Nishigori C, Nishimura Y, Kobayashi K. Cross-sectional study of cholinergic urticaria subtypes and bronchial hyperresponsiveness. Sci Rep. 2022 Oct 27;12:18122.

Mimura C, Kaneshiro K, Fujimoto S, Dokuni R, Iwamoto N, Matsumura K, Hatakeyama Y, Kono Y, Tachihara M. TAPO in first-line osimertinib therapy and continuation of Osimertinib. Thorac Cancer. 2023;14:584-591.

Yamada J, Hazama D, Tachihara M, Kawanami Y, Kawaguchi A, Yatani A, Sato H, Mimura C, Katsurada N, Yamamoto M, Nishimura Y, Kobayashi Y. The utility of bispectral index monitoring in flexible bronchoscopy: A single-center, retrospective observational study. Thorac Cancer. 2022; 13: 3052-3057.

Terai H, Soejima K, Shimokawa A, Horinouchi H, Shimizu J, Hase T, Kanemaru R, Watanabe K, Ninomiya K, Aragane N, Yanagitani N, Sakata Y, Seike M, Fujimoto D, Kasajima M, Kubo A, Kusumoto S, Oyamada Y, Fujiwara K, Mori M, Hashimoto M, Shingyoji M, Kodani M, Sakamoto J, Agatsuma T, Kashiwabara K, Inomata M, Tachihara M, Tanaka K, Hayashihara K, Koyama N, Matsui K, Minato K, Jingu D, Sakashita H, Hara S, Naito T, Okada A, Tanahashi M, Sato Y, Asano K, Takeda T, Nakazawa K, Harada T, Shibata K, Kato T, Miyaoka E, Yoshino I, Gemma A, Mitsudomi T. Real-World Data Analysis of Pembrolizumab Monotherapy for NSCLC Using Japanese Postmarketing All-Case Surveillance Data. JTO Clin Res Rep. 2022 3:100404.

Nomura N, Matsumoto H, Yokoyama A, Nishimura Y, Asano K, Niimi A, Tohda Y, Harada N, Nagase H, Nagata M, Inoue H, Kondo M, Horiguchi T, Miyahara N, Hizawa N, Hojo M, Hattori N, Hashimoto N, Yamasaki A, Kadowaki T, Kimura T, Miki M, Taniguchi H, Toyoshima M, Kawamura T, Matsuno O, Sato Y, Sunadome H, Nagasaki T, Oguma T, Hirai T; BEXAS study.　Nationwide survey of refractory asthma with bronchiectasis by inflammatory subtypes. Respir Res. 2022 ;23:365.

Kurahashi Y, Furukawa K, Sutandhio S, Tjan LH, Iwata S, Sano S, Tohma Y, Ohkita H, Nakamura S, Nishimura M, Arii J, Kiriu T, Yamamoto M, Nagano T, Nishimura Y, Mori Y. Cross-neutralizing activity against Omicron could be obtained in SARS-CoV-2 convalescent patients who received two doses of mRNA vaccination J Infect Dis. 2022 May 5:jiac178.

1年間経過した魚骨を全身麻酔下で摘出した気管支異物の1例
矢谷敦彦，黒田栞，山本正嗣，立原素子，山田潤，羽間大祐，桂田直子，松村考，清水奈保子，西村善博
気管支学, 44(1): 50-53, 2022

クロピドグレルによる薬剤誘発性ループスの1例
高宮麗，岡村佳代子，塚本玲，松尾健二郎，池田美穂，大西尚
日呼吸誌, 11(4): 207-211, 2022

(総説)毎年冬に必ず出るせき
永野達也
Health＆Life　2022年1月号

（総説）【喘息の発症メカニズムと治療・管理】疫学、遺伝、発症予防　喘息の疫学
永野 達也, 西村 善博
医学のあゆみ2022年281巻1号 Page4-7

（総説）アレルギー用語解説シリーズ　Airway epithelial basal cell
佐藤 宏紀, 永野 達也, 西村 善博
アレルギー2022年71巻3号 Page254-255

（総説）【難治性慢性咳嗽治療の新展開-ゲーファピキサントへの期待-】原因疾患別の診断と治療　最新のガイドラインを踏まえて　喘息/咳喘息
永野 達也, 西村 善博
Progress in Medicine 2022年42巻6号 Page541-544

（総説）アレルギー用語解説シリーズ　腸内細菌叢とアレルギー
安井 裕美, 永野 達也, 西村 善博
日本喘息学会誌　1 (1), 46-48, 2022年

（総説）長時間作用性抗コリン薬（LAMA）
永野達也，西村善博
Health＆Life　2022年1月号

（総説）呼吸器領域におけるがんゲノム医療
永野達也, 國政啓, 眞庭謙昌
日本気管食道科学会　専門医通信　第65号, 17-21, 2022年

Tjan LH, Nagano T, Furukawa K, Nishimura M, Arii J, Fujinaka S, Iwata S, Sano S, Tohma Y, Nishimura Y, Mori Y. The Neutralizing Antibody Response against Severe Acute Respiratory Syndrome Coronavirus 2 and the Cytokine/Chemokine Release in Patients with Different Levels of Coronavirus Diseases 2019 Severity: Cytokine Storm Still Persists Despite Viral Disappearance in Critical Patients. JMA J. 2021 Jan 29; 4(1): 1–7.

Tjan LH, Furukawa K, Nagano T, Kiriu T, Nishimura M, Arii J, Hino Y, Iwata S, Nishimura Y, Mori Y. Early differences in cytokine production distinguish severity of COVID-19. J Infect Dis. 2021 Apr 8;223(7):1145-1149

Akamatsu H, Toi Y, Hayashi H, Fujimoto D, Tachihara M, Furuya N, Otani S, Shimizu J, Katakami N, Azuma K, Miura N, Nishino K, Hara S, Teraoka S, Morita S, Nakagawa K, Yamamoto N. Efficacy of Osimertinib Plus Bevacizumab vs Osimertinib in Patients With EGFR T790M-Mutated Non-Small Cell Lung Cancer Previously Treated With Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor: West Japan Oncology Group 8715L Phase 2 Randomized Clinical Trial. JAMA Oncol. 2021;7(3):386-394.

Takeda M, Shimokawa M, Nakamura A, Nosaki K, Watanabe Y, Kato T, Hayakawa D, Tanaka H, Takahashi T, Kogure Y, Tachihara M, Fujimoto D, Yamaguchi K, Hamaguchi N, Okamoto I, Azuma K, Hasegawa K, Yamamoto N, Nakagawa K. A Phase II Study to Assess the Efficacy of Osimertinib in Patients With EGFR Mutation-positive NSCLC Who Developed Isolated CNS Progression (T790M-negative or Unknown) During First- or Second-generation EGFR-TKI or Systemic Disease Progression (T790M-negative) After Treatment With First- or Second-generation EGFR-TKI and Platinum-based Chemotherapy (WJOG12819L) Clin Lung Cancer. 2021 Jan 25:S1525-7304(20)30352-1.

Furukawa K, Arii J, Nishimura M, Tjan LH, Lystia Poetranto A, Ren Z, Aktar S, Huang JR, Sutandhio S, Kurahashi Y, Nishino A, Shigekuni S, Takeda Y, Uto K, Matsui K, Sato I, Inui Y, Endo K, Kosaka Y, Oota T, Saegusa J, Mori Y. Seroepidemiological Survey of the Antibody for Severe Acute Respiratory Syndrome Coronavirus 2 with Neutralizing Activity at Hospitals: A Cross-sectional Study in Hyogo Prefecture, Japan. JMA J. 2021 Jan 29; 4(1): 41-49.

Suraya R, Nagano T, Katsurada M, Sekiya R, Kobayashi K, Nishimura Y. Molecular mechanism of asthma and its novel molecular target therapeutic agent. Respir Investig. 2021 May;59(3):291-301.

Yoshizaki A, Nagano T, Izumi S, Funada Y, Nakata K, Nishiuma T, Takatsuki K, Ohnishi H, Hazeki N, Yasuda Y, Dokuni R, Yamamoto M, Kobayashi K, Nishimura Y. Prospective Study of Nocturnal Desaturation in Patients Receiving Home Oxygen Therapy. Internal Medicine. 2021 Oct 1; 60 (19):3071-3079.

Mimura C, Tachihara M, Kusuhara S, Fukuoka H, Nishimura Y Complete response in a patient with lung cancer suffering from three pembrolizumab‐induced immune‐related adverse events including retinal vasculitis. Respirol Case Rep. 2021 Apri;9(4): e00730

Zenke Y, Tsuboi M, Chiba Y, Tsujino K, Satouchi M, Sawa K, Shimizu J, Daga H, Fujimoto D, Mori M, Aoki T, Sawa T, Omori S, Saka H, Iwamoto Y, Okuno M, Hirashima T, Kashiwabara K, Tachihara M, Ymamoto N, Nakagawa K. Effect of Second-generation vs Third-generation Chemotherapy Regimens With Thoracic Radiotherapy on Unresectable Stage III Non-Small-Cell Lung Cancer: 10-Year Follow-up of a WJTOG0105 Phase 3 Randomized Clinical Trial. JAMA Oncol. 2021 Mar 18;7(6):904-909.

Tanabe N, Kumamaru H, Tamura Y, Taniguchi H, Emoto N, Yamada Y, Nishiyama O, Tsujino I, Kuraishi H, Nishimura Y, Kimura H, Inoue Y, Morio Y, Nakatsumi Y, Satoh T, Hanaoka M, Kusaka K, Sumitani M, Handa T, Sakao S, Kimura T, Kondoh Y, Nakayama K, Tanaka K, Ohira H, Nishimura M, Miyata H, Tatsumi K; JRPHS Group. Multi-Institutional Prospective Cohort Study of Patients With Pulmonary Hypertension Associated With Respiratory Diseases. Circ J. 2021 Mar 25;85(4):333-342.

Kim KW, Kusuhara S, Tachihara M, Mimura C, Matsumiya W, Nakamura M. A case of panuveitis and retinal vasculitis associated with pembrolizumab therapy for metastatic lung cancer. Am J Ophthalmol Case Rep. 2021 Mar 12;22:101072.

Zhang T, Sun B, Zhong C, Xu K, Wang Z, Hofman P, Nagano T, Legras A, Breadner D, Ricciuti B, Divisi D, Schmid RA, Peng RW, Yang H, Yao F. Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma. Transl Lung Cancer Res. 2021 Apr;10(4):1857-1872.

Nakajima T, Nagano T, Nishimura Y. Retrospective Study of the Effects of Post-nasal Drip Symptoms on Cough Duration. In Vivo. 2021 May-Jun;35(3):1799-1803.

Katsurada M, Nagano T, Nakajima T, Yasuda Y, Miwa N, Sekiya R, Kobayashi K, Hojo D, Nishimura Y. Retrospective analysis of the effect of inhaler education on improvements in inhaler usage. Respir Investig. 2021 May;59(3):312-319.

Bai S, Tian T, Pacheco JM, Tachihara M, Hu P, Zhang J. Immune-related adverse event profile of combination treatment of PD-(L)1 checkpoint inhibitors and bevacizumab in non-small cell lung cancer patients: data from the FDA adverse event reporting system. Transl Lung Cancer Res. 2021 Jun;10(6):2614-2624.

Kim YH, Nishimura Y, Funada Y. How should we manage non-small-cell lung cancer "not-otherwise-specified"? Med Oncol. 2021 Jun 12;38(7):82.

Takemura T, Kataoka Y, Shirakawa C, Okazaki K, Sakurai A, Imakita T, Ikegaki S, Matsumoto H, Saito E, Takata H, Kaku S, Wada N, Shinomiya M, Otoshi T, Shimada M, Nikaido J, Iki R, Hirano K, Hirai T, Endo K, Hirabayashi M, Naganuma T Influence of loneliness and social isolation on the diagnosis and treatment of Japanese patients with advanced lung cancer: a prospective cohort study. Ann Palliat Med. 2021 Jun 10(6):6236-6246.

Furukawa K, Tjan LH, Sutandhio S, Kurahashi Y, Iwata S, Tohma Y, Sano S, Nakamura S, Nishimura M, Arii J, Kiriu T, Yamamoto M, Nagano T, Nishimura Y, Mori Y. Cross-Neutralizing Activity Against SARS-CoV-2 Variants in COVID-19 Patients: Comparison of 4 Waves of the Pandemic in Japan. Open Forum Infect Dis. 2021;8(10):ofab430.

Effendi WI, Nagano T. The Crucial Role of NLRP3 Inflammasome in Viral Infection-Associated Fibrosing Interstitial Lung Diseases. Int J Mol Sci. 2021 Sep 28;22(19):10447.

Hayashi H, Sugawara S, Fukuda Y, Sato Y, Miura S, Ota K, Ozawa Y, Hara S, Tanizaki J, Azuma K, Omori S, Tachihara M, Nishino K, Hosokawa S, Chiba Y, Haratani K, Sakai K, Nishio K, Yamamoto N, NakagawaK.A Randomized Phase 2 Study Comparing Nivolumab with Carboplatin-Pemetrexed for EGFR-Mutated NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors (WJOG8515L). Clin Lung Cancer. 2022;28(5):893-902.

Tachihara M, Tsujino K, Ishihara T, Hayashi H, Sato Y, Kurata T, Sugawara S, Okamoto I, Teraoka S, Azuma K, Daga H, Yamaguchi M, Kodaira K, Satouchi M, Shimokawa M, Yamamoto N, Nakagawa K. Phase II Study of Durvalumab Plus Concurrent Radiation Therapy in Locally Advanced Non–Small Cell Lung Cancer: The DOLPHIN Study (WJOG11619L). Cancer Manag Res. 2021;13:9167-9173.

Yoshizaki A, Nagano T, Izumi S, Nishiuma T, Nakata K, Yamamoto M, Yasuda Y, Hazama D, Umezawa K, Katsurada N, Tachihara M, Nishimura Y, Kobayashi K. Characteristics of the nocturnal desaturation waveform pattern of SpO2 in COPD patients: an observational study. Respiratory Research. 2021 Oct 26;22(1):276.

Takanori Enomoto, Reina Sekiya, Hiroshi Sugimoto, Tomomi Terashita, Junya Yoshioka, Tatsuya Nagano, Yoshihiro Nishimura, Erika Yano, Tatsuya Moriyama, Kyosuke Nakata A case of hypersensitivity pneumonitis caused by Grey parrot (Psittacus erithacus) Internal Medicine, 2021 Dec 28. doi: 10.2169/internalmedicine.8679-21. Online ahead of print.

Otoshi T, Nagano T, Izumi S, Hazama D, Katsurada N, Yamamoto M, Tachihara M, Kobayashi K, Nishimura Y A novel automatic cough frequency monitoring system combining a triaxial accelerometer and a stretchable strain sensor. Sci Rep. 2021;11:9937

Ouchi A, Kim YH, Iwatsubo S, Nishimura Y, Funada Y. Re-thinking about prophylactic cranial irradiation for small cell lung cancer in the MRI era. J Thorac Dis. 2021 Aug;13(8):5115-5116.

Otoshi T, Nagano T, Murakami S, Omori T, Hazama D, Katsurada N, Yamamoto M, Tachihara M, Nishimura Y, Kobayashi K A randomized crossover pilot study comparing the efficacy of an auto-demand oxygen delivery system with that of a conventional demand oxygen delivery system in patients with chronic respiratory failure. Medicine (Baltimore). 2021 Sep 17; 100(37):e27191

Yamaoka T, Kim YH, Iwatsubo S, Nishimura Y, Funada Y. The Role of Dual Inhibition of EGFR and Vascular Endothelial Growth Factor (Receptor) in the Treatment of NSCLC With EGFR Mutation. J Thorac Oncol. 2021 Sep;16(9):e71-e72.

Katsurada N, Tachihara M, Jimbo N, Yamamoto M, Yoshioka J, Mimura C, Satoh H, Furukawa K, Otoshi T, Kiriu T, Yasuda Y, Tanaka T, Nagano T, Nishimura Y. Yield of tumor samples with a large guide-sheath in endobronchial ultrasound transbronchial biopsy for non-small cell lung cancer: A prospective study. PLoS One. 2021 Oct 29;16(10):e0259236.

Yamasaki N, Kim YH, Iwatsubo S, Nishimura Y, Funada Y. Role of Postoperative Radiotherapy in Patients With Completely Resected pIIIA-N2 Non-Small Cell Lung Cancer. Clin Lung Cancer. 2021 Oct 2:S1525-7304(21)00249-7

Suraya R, Nagano T, Katsurada M, Sekiya R, Kobayashi K, Nishimura Y. Molecular mechanism of asthma and its novel molecular target therapeutic agent. Respir Investig. 2021; 59:291-301

Effendi WI, Nagano T. The Hedgehog Signaling Pathway in Idiopathic Pulmonary Fibrosis: Resurrection Time. Int J Mol Sci. 2021; 23:171

Fujimoto D, Miura S, Yoshimura K, Wakuda K, Oya Y, Haratani K, Itoh S, Uemura T, Morinaga R, Takahama T, Nakashima K, Tachihara M, Saito G, Tanizaki J, Otsubo K, Ikeda S, Matsumoto H, Hara S, Hata A, Masuda T, Yamamoto N. A Real-World Study on the Effectiveness and Safety of Pembrolizumab Plus Chemotherapy for Nonsquamous NSCLC. JTO Clin Res Rep. 2021;3(2):100265.

Megasari NLA, Utsumi T, Yamani LN, Juniastut, Gunawan E, Furukawa K, Nishimura M, Lusida MI, Mori Y. Seroepidemiological study of SARS-CoV-2 infection in East Java, Indonesia. PLoS One. 2021 May 6;16(5):e0251234.

Nakajima T, Nagano T, Hojo D, Nishimura Y. An Investigation on the Consciousness of Patients and Pharmacists Regarding Inhaler Education. Kobe J Med Sci. 2021 67:E119-E124

Nagase H, Nishimura Y, Matsumoto H, Sugimoto N, Iwanaga T, Sano A, Konno S, Hizawa N, Asano K, Horiguchi T, Yokoyama A; Japanese Respiratory Society, Scientific Assembly for Allergy, Immunology, and Inflammation. The prevalence of comorbid respiratory disease among COVID-19 patients, and mortality during the first wave in Japan: A nationwide survey by the Japanese Respiratory Society. Respir Investig. 2021 59 :679-682.

Kitazawa H, Hizawa N, Nishimura Y, Fujisawa T, Iwanaga T, Sano A, Nagase H, Matsumoto H, Horiguchi T, Konno S, Asano K. The impact of the COVID-19 pandemic on asthma treatment in Japan: Perspectives based on doctors' views. Respir Investig. 2021 59:670-674.

(総説)アレルギー用語解説シリーズ　アトピー咳嗽　
安田裕一郎、永野達也
アレルギー、第70巻１号、Page46-47

(総説)ハウスダストマイト誘導性喘息マウスモデルにおける自然免疫系のかかわり　　
安田裕一郎、永野達也、西村善博
臨床免疫・アレルギー科、第75巻3号、Page348-354

気管支鏡検査で診断した神経鞘腫の2例
吉岡潤哉、立原素子、桐生辰徳、高田尚哉、梅澤佳乃子、桂田雅大、桂田直子、山本正嗣、西村善博
気管支学43(2): 168-174, 2021

日本呼吸器学会会員における大学院進学に関する最近の動向
髙橋　浩一郎，小林　信明，浅井　一久，礒部　威，今泉　和良，大平　徹郎，長内　忍，川山　智隆，國近　尚美，小林　和幸，佐野　博幸，多賀谷悦子，千葉　弘文，橋本　直純，須田　隆文，金子　猛
日呼吸誌, 10(3): 207-211, 2021

(総説)アレルギー用語解説シリーズ　好酸球性多発血管炎性肉芽腫症;EGPA
福井崇文，永野達也，西村善博
第70巻10号、Page 1398-1399

(総説)夏場に多い過敏性肺炎とは
西村善博
健康教室　2021年　第72巻　第8号

(総説)気管支喘息の分子機序
永野達也、西村善博
医学と薬学　2021年　第78巻　第12号　Page1505-1509

(書籍)過敏性肺炎
西村善博
私の治療2021-22年度版、猿田享男、北村惣一朗編、日本医事新報社、2021、214

(書籍)副腎皮質ステロイド薬
西村善博
呼吸器疾患最新の治療2021－2022、門田淳一、弦間昭彦、西岡安彦編　南江堂　2021，85-87

(書籍)生物学的製剤（抗IgE抗体薬、抗IL-5抗体を含む）
西村善博
呼吸器専門医テキスト　改訂版２版　日本呼吸器学会編　2020、204-206

(書籍)オシメルチニブ、ゲフィチニブ
立原素子
がんロコモハンドブック　総合医学社　2021年10月

(書籍)新型コロナウイルスに対する抗体調査
古川皓一、森康子
大阪大学医学部学友会会誌 2021 Vol.41, 97-100

Yoshizaki A, Yamamoto M, Hirabayashi A, Ono Y, Hatakeyama Y, Nakata K,
Tamura D, Tachihara M, Kamiryo H, Kobayashi K, Nsihio M, Nishimura Y.
Fatal Hemoptysis Due to Endobronchial Aspergilloma in the Hyperinflated Native Lung after Single-Lung Transplantation for Lymphangioleiomyomatosis: A Case Report
Kobe Journal of Medical Sciences 2020 Jan 20;65(4):E114-E117

Katsurada N, Tachihara M, Hatakeyama Y, Koyama K, Yumura,M, Kiriu T, Dokuni R, Hazama D, Tokunaga S, Tamura D, Nakata K, Yamamoto M, Kamiryo H, Kobayashi K, Tanaka Y, Maniwa Y, NishimuraY.
Feasibility Study of Adjuvant Chemotherapy with Carboplatin and Nab-Paclitaxel for Completely Resected NSCLC.
Cancer Manag Res. 2020; 12: 777782. 

Nagano T, Tachihara M, Hazama D, Nishimura Y. Society for Translational Medicine consensus (2019 edition) shows an option for postoperative management of EGFR-mutant lung cancer. J Thorac Dis, 2020 Aug;12(8):4561-4563.

Tachihara M, Dokuni R, Okuno K, Tokunaga S, Nakata K, Katsurada N, Yamamoto M, Nagano T, Kobayashi K, Tanaka Y, Funada Y, Maniwa Y, Nishimura Y. Phase II study of adjuvant chemotherapy with pemetrexed and cisplatin with a short hydration method for completely resected nonsquamous non-small cell lung cancer. Thorac Cancer. 2020 Sep;11(9):2536-2541.

Suraya R, Nagano T, Kobayashi K, Nishimura Y. Microbiome as a Target for Cancer Therapy. Integr Cancer Ther. 2020 Jan-Dec;19:1534735420920721.

Sekiya R, Nagano T, Moriyama T, Kishi T, Shinke H, Yano E, Hatano N, Katsurada M, Umezawa K, Katsurada N, Hori S, Hazeki N, Fukunaga A, Yamamoto M, Kamiryo H, Shinohara M, Kobayashi K, Kotani Y, Nishimura Y. Occupational respiratory allergy to lettuce in lettuce farmers. Clin Exp Allergy. 2020 Jun 15. doi: 10.1111/cea.13682.

Nagano T, Arii J, Nishimura M, Yoshida N, Iida K, Nishimura Y, Mori Y. Diligent medical activities of a publicly designated medical institution for infectious diseases pave the way for overcoming COVID-19: A positive message to people working at the cutting edge. Clin Infect Dis. 2020 May 31:ciaa694. doi: 10.1093/cid/ciaa694.

Effendi WI, Nagano T, Hasan H, Yudhawati R. Immunoregulatory Property of C-Type Lectin-Like Receptors in Fibrosing Interstitial Lung Diseases. Int J Mol Sci. 2020 May 22;21(10):3665.

Yasuda Y, Nagano T, Kobayashi K, Nishimura Y. Group 2 Innate Lymphoid Cells and the House Dust Mite-Induced Asthma Mouse Model. Cells. 2020 May 9;9(5):1178.

Nagano T, Kobayashi K, Omori T, Otoshi T, Umezawa K, Katsurada N, Yamamoto M, Tachihara M, Nishimura Y. Randomized cross-over trial of demand oxygen delivery system in nocturnal hypoxemia. Medicine (Baltimore). 2020 May;99(19):e20031.

Nagano T, Kobayashi K, Omori T, Otoshi T, Umezawa K, Katsurada N, Yamamoto M, Tachihara M, Nishimura Y. Randomized cross-over trial of demand oxygen delivery system. Medicine (Baltimore). 2020 May;99(19):e20010.

Effendi WI, Nagano T, Kobayashi K, Nishimura Y. Focusing on Adenosine Receptors as a Potential Targeted Therapy in Human Diseases. Cells. 2020 Mar 24;9(3):785.

Ikegaki S, Otoshi T, Hirai T, Hirabayashi M. A rare case of parathyroid crisis with respiratory failure successfully treated using extracorporeal membrane oxygenation. Respir Med Case Rep. 2020 May 11;30:101088.

Sato H, Tachihara M, Kiriu T, Yamamoto M, Tanaka Y, Nishimura Y. Pulmonary large cell neuroendocrine carcinoma with adrenal oligorecurrence successfully treated by adrenalectomy. Respirol Case Rep. 2020;8(6):e00618.

Shiraishi Y, Kishimoto J, Tanaka K, Sugawara S, Daga H, Hirano K, Azuma K, Hataji O, Hayashi H, Tachihara M, Mitsudomi T, Seto T, Nakagawa K, Yamamoto N, Okamoto I.Treatment Rationale and Design for APPLE (WJOG11218L): A Multicenter, Open-Label, Randomized Phase 3 Study of Atezolizumab and Platinum/Pemetrexed With or Without Bevacizumab for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2020 Apr 10:S1525-7304(20)30089-9.

Tanaka K, Morita S, Ando M, Yokoyama T, Nakamura A, Yoshioka H, Ishiguro T, Miura S, Toyozawa R, Oguri T, Daga H, Ko R, Bessho A, Tachihara M, Iwamoto Y, Hirano K, Nakanishi Y, Nakagawa K, Yamamoto N, Okamoto I. A randomized phase 3 study of maintenance therapy with S-1 plus best supportive care versus best supportive care after induction therapy with carboplatin plus S-1 for advanced or relapsed squamous cell carcinoma of the lung (WJOG7512L).　Cancer. 2020 ;126(16):3648-3656.

Hazama D, Yin Y, Murata Y, Matsuda M, Okamoto T, Tanaka D, Terasaka N, Zhao J, Sakamoto M, Kakuchi Y, Saito Y, Kotani T, Nishimura Y, Nakagawa A, Suga H, Matozaki T. Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy. Cell Chem Biol. 2020 Jul 1:S2451-9456(20)30231-2.

Masako Y, Taysuya N, Yoshihiro N. Novel Multitarget Therapies for Lung Cancer and Respiratory Disease. Molecules 2020 July 25(17), 3987.

Nagano T, Tachihara M, Hazama D, Nishimura Y. Society for Translational Medicine consensus (2019 edition) shows an option for postoperative management of EGFR-mutant lung cancer. J Thorac Dis. 2020 Aug;12(8):4561-4563.

Miwa N, Nagano T, Jimbo N, Dokuni R, Kiriu T, Mimura C, Yasuda Y, Katsurada M, Yamamoto M, Tachihara M, Tanaka Y, Kobayashi K, Itoh T, Maniwa Y, Nishimura Y. Caspase Recruitment Domain-Containing Protein 9 Expression is a Novel Prognostic Factor for Lung Adenocarcinoma. Onco Targets Ther. 2020 Sep 10;13:9005-9013.

Hazama D, Yin Y, Murata Y, Matsuda M, Okamoto T, Tanaka D, Terasaka N, Zhao J, Sakamoto M, Kakuchi Y, Saito Y, Kotani T, Nishimura Y, Nakagawa A, Suga H, Matozaki T. Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy. Cell Chem Biol. 2020 Sep 17;27(9):1181-1191.

Furukawa K, Nagano T, Tachihara M, Yamamoto M, Nishimura Y.　Interaction between Immunotherapy and Antiangiogenic Therapy for Cancer. Molecules. 2020 Aug 26;25(17):3900.

Nakajima T, Nagano T, Suraya R, Kawafune Y, Hojo D, Kato H, Nishimura Y. A Questionnaire Survey of the Inhalation Instruction in Pharmacies. Kobe J Med Sci. 2020 Nov 17;66(3):E113-E118.

Dokuni R, Nagano T, Jimbo N, Sato H, Kiriu T, Yasuda Y, Yamamoto M, Tachihara M, Kobayashi K, Maniwa Y, Nishimura Y. High expression level of serpin peptidase inhibitor clade E member 2 is associated with poor prognosis in lung adenocarcinoma. Respir Res. 2020 Dec 14;21(1):331.

呼吸器内科医師の海外留学に関するアンケート調査
小林信明，髙橋浩一郎，浅井一久，礒部威，今泉和良，大平徹郎，長内忍，川山智隆，國近尚美，小林和幸，佐野博幸，多賀谷悦子，千葉弘文，橋本直純，須田隆文，金子猛
日呼吸誌, 10(2): 102-107, 2021

多発脳腫瘍に対し血漿検査で診断しオシメルチニブによる治療効果が得られた1例
三村　千尋、山本　正嗣、行田　まな、藤岡　美結、小山　貴代子、湯村　真沙子、寺下　智美、桂田　直子、梅澤　佳乃子、立原　素子、小林　和幸、西村　善博
癌と化学療法　第48巻第5号（5月号）に掲載予定

呼吸器症状の鑑別におけるモストグラフの有用性についての検討
西馬 照明, 堀 朱矢, 徳永 俊太郎, 藤井 真央, 石田 貢一, 山本 賢, 西村 善博
アレルギーの臨床 40巻7号 Page579-582, 2020

ヒト化抗インターロイキン-5受容体αモノクローナル抗体製剤ベンラリズマブの特定使用成績調査　中間報告
西村 善博, 山口 正雄, 堀田 麻里子, 林 暢哉, 坂本 慶, 時本 敏充, 東田 有智
Therapeutic Research 41巻9号 Page747-759, 2020

(総説) 医療介護関連肺炎 (NHCAP)の治療
桂田直子 medicina 57巻: 62-65項, 2020年

(総説) Resident eosinophils
堂國良太、西村善博
アレルギー、第69巻1号、Page61

(総説) 治療法の再整理とアップデートのために　専門家による私の治療　過敏性肺炎
西村 善博
日本医事新報5002号 Page38, 2020年

(総説) アレルギー用語解説シリーズ　Resident eosinophils
堂國良太、西村善博
アレルギー、第69巻1号、Page61, 2020

(総説) アレルギー用語解説シリーズ　好塩基球活性化試験(BAT)
吉岡潤哉、西村善博
アレルギー 第69巻8号 Page710-711, 2020

(書籍) 遷延性咳嗽
西村善博
今日の治療指針2020　福井崇文次矢、高木誠、小室一成編　医学書院　295-297, 2020

(書籍) アレルギー性気管支肺真菌症
西村善博
今日の治療指針2020　福井崇文次矢、高木誠、小室一成編　医学書院　843-845, 2020

(書籍) PD-L1について
遺伝子変異パネル検査
デュルバルマブ
立原素子　
肺癌診療 虎の巻 WJOG 肺がんグループのプラクティス 監修　山本信之　クリニコ出版

Tachihara M, Kiriu T, Hata A, Hatakeyama Y, Nakata K, Nagano T,
Yamamoto M, Kobayashi K, Ohnishi H, Katakami N, Nishimura Y.
A multi-center, Phase II trial of nab-paclitaxel and gemcitabine in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy.
Cancer Manag Res. 2019 Jul 29;11:7135-7140.

Katsurada N, Nishimura Y.
Viral pneumonia: which patients should we focus on?
Infect Dis (Lond). 2019 Jul;51(7):510-511.

Murakami S, Nagano T, Nakata K, Onishi A, Umezawa K, Katsurada N, Yamamoto M,
Tachihara M, Kobayashi K, Nishimura Y.
Tenosynovitis Induced by an Immune Checkpoint Inhibitor: A Case Report and Literature Review.
Intern Med. 2019 Oct 1;58(19):2839-2843.

Tachihara M, Nishimura Y.
Who will suffer from hyperprogressive disease in patients with advanced non-small cell lung cancer treated with PD-1/PD-L1 inhibitors.
J Thorac Dis. 2019 May;11(Suppl 9):S1289-S1291.

Katsurada N, Ohnishi H, Ikeda M, Jimbo N, Hatakeyama Y, Okamura K.
Primary pleural synovial sarcoma with repeated resection leading to long-term survival.
Respirol Case Rep. 2019 Aug 20;7(8):e00480.

Nagano T, Katsurada M, Dokuni R, Hazama D, Kiriu T, Umezawa K, Kobayashi K, Nishimura Y.
Crucial Role of Extracellular Vesicles in Bronchial Asthma.
Int J Mol Sci. 2019 May 27;20(10). pii: E2589.

Nagano T, Otoshi T, Hazama D, Kiriu T, Umezawa K, Katsurada N, Nishimura Y.
Novel cancer therapy targeting microbiome.
Onco Targets Ther. 2019 May 13;12:3619-3624.

Effendi WI, Nagano T, Tachihara M, Umezawa K, Kiriu T, Dokuni R, Katsurada M, Yamamoto M,
Kobayashi K, Nishimura Y.
Synergistic interaction of gemcitabine and paclitaxel by modulating acetylation and polymerization of tubulin in non-small cell lung cancer cell lines.
Cancer Manag Res. 2019 Apr 29;11:3669-3679.

Nagano T, Katsurada M, Yasuda Y, Kobayashi K, Nishimura Y.
Current pharmacologic treatments for smoking cessation and new agents undergoing clinical trials.
Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619875925.

Nagano T, Tachihara M, Nishimura Y.
Dacomitinib, a second-generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) to treat non-small cell lung cancer.
Drugs Today (Barc). 2019 Apr;55(4):231-236.

Otoshi T, Nagano T, Tachihara M, Nishimura Y.
Possible Biomarkers for Cancer Immunotherapy.
Cancers (Basel). 2019 Jul 3;11(7). pii: E935.

Koyama K, Katsurada N, Jimbo N, Tachihara M, Tamura D, Nakata K, Nagano T,
Yamamoto M, Kamiryo H, Kobayashi K, Itoh T, Nishimura Y.
Overexpression of CD 133 and BCL-2 in non-small cell lung cancer with neuroendocrine differentiation after transformation in ALK rearrangement-positive adenocarcinoma.
Pathol Int. 2019 May;69(5):294-299.

Yasuda Y, Nagano T, Tachihara M, Chihara N, Umezawa K, Katsurada N, Yamamoto M,
Sekiguchi K, Kobayashi K, Nishimura Y.
Eosinophilic Pneumonia Associated With Natalizumab In A Patient With Multiple Sclerosis: A Case Report And Literature Review
Ther Clin Risk Manag 2019 in press

Akamatsu H, Teraoka S, Morita S, Katakami N, Tachihara M, Daga H, Yamamoto N, Nakagawa K.
Phase I/II Study of Osimertinib With Bevacizumab in EGFR-mutated, T790M-positive Patients With Progressed EGFR-TKIs: West Japan Oncology Group 8715L (WJOG8715L).
Clin Lung Cancer. 2019 Jul;20(4):e492-e494.

Chayahara N, Mukohara T, Tachihara M, Fujishima Y, Fukunaga A, Washio K, Yamamoto M, Nakata K,
Kobayashi K, Takenaka K, Toyoda M, Kiyota N, Tobimatsu K, Doi H, Mizuta N, Marugami N, Kawaguchi A,
Nishigori C, Nishimura Y, Minami H.
Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti-Epidermal Growth Factor Receptor-Induced Acne-Like Rash: A Randomized Left-Right Comparative Evaluation (APPEARANCE).
Oncologist. 2019 Jul;24(7):885-e413.

Kiriu T, Yamamoto M, Nagano T, Koyama K, Katsurada M, Tamura D, Nakata K,
Tachihara M, Kobayashi K, Nishimura Y.
Prognostic Value of Red Blood Cell Distribution Width in Non-small Cell Lung Cancer Treated With Anti-programmed Cell Death-1 Antibody
In Vivo. 2019 Jan-Feb;33(1):213-220. doi: 10.21873/invivo.11462.

Katsurada M, Nagano T, Tachihara M, Kiriu T, Furukawa K, Koyama K, Otoshi T, Sekiya R, Hazama D,
Tamura D, Nakata K, Katsurada N, Yamamoto M, Kobayashi K, Nishimura Y.
Baseline Tumor Size as a Predictive and Prognostic Factor of Immune Checkpoint Inhibitor Therapy for Non-small Cell Lung Cancer.
Anticancer Res. 2019 Feb;39(2):815-825. doi: 10.21873/anticanres.13180.

Katsurada N, Tachihara M, Jimbo N, Koyama K, Nakata K, Nagano T, Yamamoto M, Kamiryo H,
Kobayashi K, Nishimura Y.
Successful Treatment of ROS1-rearranged Lung Cancer Complicated by Hypertrophic Pulmonary Osteoarthropathy with Crizotinib Therapy: A Case Report.
Intern Med. 2019 Jan 10 doi: 10.2169/internalmedicine.1982-18

Umezawa K, Nagano T, Kobayashi K, Dokuni R, Katsurada M, Yamamoto M, Yoshikawa Y, Kataoka T, Nishimura Y.
Phospholipase Cε plays a crucial role in　neutrophilic inflammation accompanying　acute lung injury through augmentation of　CXC chemokine production from alveolar　epithelial cells
Respiratory Research. 2019;20(9).

Tachihara M, Yamamoto M, Yumura M, Yoshizaki A, Kobayashi K, Nishimura Y.
Non-parallel anti-tumour effects of pembrolizumab: a case of cardial tamponade.
Respirol Case Rep. 2019 Jan 31;7(3):e00404.

Otoshi T, Nagano T, Funada Y, Takenaka K, Nakata H, Ohnishi H, Nishiuma T, Nakajima T,
Kageshita T, Tsuchiya T, Yamamoto M, Kobayashi K, Nishimura Y.
A Cross-sectional Survey of the Clinical Manifestations and Underlying Illness of Cough.
In Vivo. 2019 Mar-Apr;33(2):543-549.

Akamatsu H, Teraoka S, Morita S, Katakami N, Tachihara M, Daga H, Yamamoto N, Nakagawa K.
Phase I/II Study of Osimertinib With Bevacizumab in EGFR-mutated, T790M-positive Patients With Progressed EGFR-TKIs: West Japan Oncology Group 8715L (WJOG8715L).Clin Lung Cancer. 2019 Jul;20(4):e492-e494.

Chayahara N, Mukohara T, Tachihara M, Fujishima Y, Fukunaga A, Washio K, Yamamoto M, Nakata K, Kobayashi K, Takenaka K, Toyoda M, Kiyota N, Tobimatsu K, Doi H, Mizuta N, Marugami N, Kawaguchi A, Nishigori C, Nishimura Y, Minami H.
Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti-Epidermal Growth Factor Receptor-Induced Acne-Like Rash: A Randomized Left-Right Comparative Evaluation (APPEARANCE).Oncologist. 2019 Jul;24(7):885-e413.

Izumi S, Nagano T, Yoshizaki A, Nishimura Y.
Classification Algorithm for Nocturnal Hypoxemia Using Nocturnal Pulse Oximetry.
Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:3662-3665

Kiriu T, Yamamoto M, Nagano T, Hazama D, Sekiya R, Katsurada M, Katsurada N, Tachihara M, Kobayashi K, Nishimura Y.
Pseudo-Progression and the Neutrophil-to-Lymphocyte Ratio in Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors: A Case-Control Study.
Onco Targets Ther. 2019 Dec 2;12:10559-10568.

尿毒症性胸膜炎患者における局所麻酔下胸腔鏡検査による胸膜病変の検討
梅澤 佳乃子, 大西 尚, 湯村 真沙子, 藤井 真央, 𠮷﨑 飛鳥, 川本 めぐみ, 尾野 慶彦, 堂國 良太, 吉村 将
気管支学 41(3):233-238,2019

抗ヒトIL-17RAモノクローナル抗体ブロダルマブを投与後に胸膜炎，大動脈炎を発症した膿疱性乾癬の1例
吉岡　愛育、福永　淳、横山　大輔、大幡　万里恵、桂田　雅大、明石 健吾、錦織 千佳子
臨床皮膚科　73(11):887-892,2019

局所麻酔下胸腔鏡下生検で診断した肺癌肉腫の芽腫様亜型の1例
堂國 良太, 立原 素子, 田村 大介, 中田 恭介, 堀 朱矢, 山本 正嗣, 上領 博, 小林 和幸, 西村 善博
気管支学 41(1):40-45,2019

(総説) 免疫関連有害事象（immune-related Adverse Events）
古川　皓一、西村善博
アレルギー　第68巻　in press

(総説) エンドタイプ
永野達也、西村善博
アレルギー、第68巻8号、Page970

(書籍)咳喘息とアトピー咳嗽
西村善博
今日の治療指針2019　福井崇文次矢、高木誠、小室一成編　医学書院　825-827, 2019

(書籍)肺がん化学療法 副作用マネジメント プロのコツ 単行本 – 2019/7/22
立原素子
倉田宝保、吉岡弘鎮、金田俊彦 編

Nagano T, Tachihara M, Nishimura Y.
Molecular Mechanisms and Targeted Therapies Including Immunotherapy for Non-Small Cell Lung Cancer. Curr Cancer Drug Targets. 2018 Dec 9. doi: 10.2174/1568009619666181210114559.

Nagano T, Tachihara M, Nishimura Y.
Mechanism of Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors and a Potential Treatment Strategy. Cells. 2018 Nov 15;7(11). pii: E212. doi: 10.3390/cells7110212.

Kiriu T, Tamura D, Tachihara M, Sekiya R, Hazama D, Katsurada M, Nakata K,
Nagano T, Yamamoto M, Kamiryo H, Kobayashi K, Nishimura Y.
Successful Osimertinib Rechallenge with Steroid Therapy after Osimertinib-induced Interstitial Lung Disease: A Case Report
Intern Med. 2018 Jan 1;57(1):91-95.

Kiriu T, Yamamoto M, Nagano T, Hazama D, Sekiya R, Katsurada M, Tamura D,
Tachihara M, Kobayashi K, Nishimura Y.
The time-series behavior of neutrophil-to-lymphocyte ratio is useful as a predictive marker in non-small cell lung cancer
PLoS One. 2018 Feb 15;13(2):e0193018

Yasuda Y, Hattori Y, Tohnai R, Ito S, Kawa Y, Kono Y, Urata Y,
Nogami M, Takenaka D, Negoro S, Satouchi M.
The safety and efficacy of carboplatin plus nanoparticle albumin-bound paclitaxel in the treatment of non-small cell lung cancer patients with interstitial lung disease
Jpn J Clin Oncol. 2018 Jan 1;48(1):89-93.

Kojima M, Nagano T, Nakata K, Hara S, Katsurada N, Yamamoto M, Tachihara M,
Kamiryo H, Kobayashi K, Usui T, Nishimura Y.
Lung squamous cell carcinoma associated with HDR syndrome: a case report
Onco Targets Ther. 2018 in press.

Nagano T, Tachihara M, Nishimura Y.
Does ipilimumab show an increased clinical benefit when combined in sequence with chemotherapy?
Transl Cancer Res. 2018 in press.

Murata Y, Tanaka D, Hazama D, Yanagita T, Saito Y, Kotani T, Oldenborg PA, Matozaki T.
Anti-human SIRPα antibody is a new tool for cancer immunotherapy
Cancer Sci. 2018 Feb 23.

Nanjo S, Hata A, Okuda C, Kaji R, Okada H, Tamura D, Irie K, Okada H, Fukushima S, Katakami N.
Standard-dose osimertinib for refractory leptomeningeal metastases in T790M-positive EGFR-mutant non-small cell lung cancer
Br J Cancer. 2018 Jan;118(1):32-37

Yasuda Y, Urata Y, Tohnai R, Ito S, Kawa Y, Kono Y, Hattori Y, Tsuda M, Sakuma T, Negoro S, Satouchi M.
Immune-related Colitis Induced by the Long-term Use of Nivolumab in a Patient with Non-small Cell Lung Cancer.
Intern Med. 2018 May 1;57(9):1269-1272.

Hata A, Katakami N, Kaji R, Yokoyama T, Kaneda T, Tamiya M, Inoue T, Kimura H, Yano Y, Tamura D, Morita S, and Negoro S on behalf of HANSHIN Oncology Group
Afatinib Plus Bevacizumab Combination After Acquired Resistance to EGFR-TKIs in EGFR-Mutant Non-Small Cell Lung Cancer: Multicenter Single Arm Phase II Trial (ABC-Study)
Cancer. 2018 in press

Tachihara M, Tamura D, Kiriu T, Tokunaga S, Hatakeyama Y, Shinke H, Nagano T, Nakata K, Hazeki N, Kamiryo H, Kobayashi K, Nishimura Y.
Bronchoscopy Using Virtual Navigation and Endobronchial Ultrasonography with a Guide Sheath (EBUS-GS) with or without Fluoroscopy for Peripheral Pulmonary Lesions.
Kobe J Med Sci. 2018 Mar 27;63(4):E99-E104.

Uchibori K, Satouchi M, Sueoka-Aragane N, Urata Y, Sato A, Imamura F, Inoue T, Tachihara M,
Kobayashi K, Katakami N, Kokan C, Hirashima T, Iwanaga K, Mori M, Aoe K, Morita S, Negoro S.
Phase II trial of gefitinib plus pemetrexed after relapse using first-line gefitinib in patients with non-small cell lung cancer harboring EGFR gene mutations
Lung Cancer. 2018 124:65-70

Yoichiro Sugizaki, Shumpei Mori, Yuichi Nagamatsu, Tomomi Akita, Akira Nagasawa, Takayoshi Toba, Masatsugu Yamamoto, Tatsuya Nishii, Norihiko Obata, Yoshikatsu Nomura, Hiromasa Otake, Toshiro Shinke, Yutaka Okita, Ken-ichi Hirata,
Critical exacerbation of idiopathic pulmonary fibrosis after transcatheter aortic valve implantation: Need for multidisciplinary care beyond “heart team”,
Journal of Cardiology Cases, 2018, in press

Suzuki M, Katsurada N, Le MN, Kaneko N, Yaegashi M, Hosokawa N, Otsuka Y, Aoshima M, Yoshida LM, Morimoto K.
Effectiveness of inactivated influenza vaccine against laboratory-confirmed influenza pneumonia among adults aged ≥65 years in Japan.
Vaccine. 2018 May 17;36(21):2960-2967.

Kishida Y, Seki S, Yoshikawa T, Itoh T, Maniwa Y, Nishimura Y, Ohno Y.
Performance Comparison Between 18F-FDG PET/CT Plus Brain MRI and Conventional Staging Plus Brain MRI in Staging of Small Cell Lung Carcinoma.
AJR Am J Roentgenol. 2018 Jul;211(1):185-192.

Tachihara M; Syunichi Negoro; Takako Inoue; Motohiro Tamiya; Yuki Akazawa; Takeshi Uenami;
Yoshiko Urata; Yoshihiro Hattori; Akito Hata; Nobuyuki Katakami; Soichiro Yokota.
Efficacy of anti-PD-1/PD-L1 antibodies after discontinuation due to adverse events in non-small cell lung cancer patients (HANSHIN 0316).
BMC cancer in press.

Ogawa H, Tanaka Y, Tachihara M, Uehara K, Shimizu N, Doi T, Hokka D, Maniwa Y.
ROS1-rearranged PD-L1 High-expression Lung Adenocarcinoma Manifesting as Mediastinal Tumor.
ONCOLOGY LETTERS. in press

Kawa Y, Nagano T, Yoshizaki A, Dokuni R, Katsurada M, Terashita T, Yasuda Y, Umezawa K, Yamamoto M, Kamiryo H, Kobayashi K, Nishimura Y.
Role of S1P/S1PR3 axis in release of CCL20 from human bronchial epithelial cells.
PLoS One. 2018 Sep 7;13(9):e0203211.

Miwa N, Nagano T, Ohnishi H, Nishiuma T, Takenaka K, Shirotani T, Nakajima T, Dokuni R, Kawa Y, Kobayashi K, Funada Y, Kotani K, Nishimura Y.
An Open-Label, Multi-Institutional, Randomized Study to Evaluate the Additive Effect of a Leukotriene Receptor Antagonist on Cough Score in Patients with Cough-Variant Asthma Being Treated with Inhaled Corticosteroids
Kobe J Med Sci. 2018 in press

経気管支針生検にて術前診断しえた炎症性筋線維芽細胞腫の1例
寺下智美，立原素子，堂國良太，吉崎飛鳥，関谷怜奈，田村大介，山本正嗣，
上領博，小林和幸，西村善博
気管支学 40(2):163-167,2018

抗インターフェロン-γ自己抗体陽性の播種性M. colombiense症の1例
尾野慶彦，山本正嗣，小濱みずき，吉崎飛鳥，小林和幸，西村善博
日呼吸誌, 7(3): 166-170, 2018

（総説）COPD慢性期治療
桂田直子・西村善博
medicina 55 (1): 106-108, 2018

（総説）ICS、ICS/LABAの使い方
湯村真沙子、西村善博
アレルギーの臨床　38(4),2018 in press.

【診断と治療のABC[140]慢性閉塞性肺疾患(COPD)】 (第4章)管理・治療　COPDの医療経済(解説/特集)
桂田雅大・西村善博
最新医学 (0370-8241)別冊慢性閉塞性肺疾患(COPD) Page219-227(2018.11)

(総説)咳喘息
三輪菜々子、西村善博
アレルギー　67(9),1281-1282,2018

(総説)COPDの呼吸生理検査の方向性‐最新のCOPD実地診療のポイント整理と活用
関谷怜奈、西村善博
Medical Practice　 35 (8) 1227-1231,2018

Hazeki N, Tachihara M, Tsukamoto R, Tokunaga S, Tamura D,
Shinke H, Kobayashi K, Sakai Y, Nishimura Y.
Utility of cell blocks obtained by catheter aspiration via
a guide sheath during endobronchial ultrasonography.
Respir Investig. 2017;55(2):161-165.

Tohda Y, Iwanaga T, Sano H, Kume H, Hirata K, Ohkura N, Tachibana I,
Nishimura Y, Matsumoto H, Minakata Y, Yoshikawa M, Fujimura M;
Kansai and Hokuriku Academy for Asthma Treatment.
Improved quality of life in asthma patients under long-term therapy:
Assessed by AHQ-Japan.
Int J Clin Pract. 2017;71(1). doi: 10.1111/ijcp.12898. Epub 2016 Dec 9.

Takahashi T, Yamanaka T, Seto T, Harada H, Nokihara H, Saka H, Nishio M,
Kaneda H, Takayama K, Ishimoto O, Takeda K, Yoshioka H, Tachihara M,
Sakai H, Goto K, Yamamoto N.
Prophylactic cranial irradiation versus observation in patients with extensive-disease
small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial.
Lancet Oncol. 2017 May;18(5):663-671.

Kunimasa K, Nagano T, Shimono Y, Dokuni R, Kiriu T, Tokunaga S, Tamura D,
Yamamoto M, Tachihara M, Kobayashi K, Satouchi M, Nishimura Y.
Glucose metabolism-targeted therapy and withaferin A are effective for epidermal
growth factor receptor tyrosine kinase inhibitor-induced drug-tolerant persisters.
Cancer Sci. 2017;108(7):1368-1377.

Tokunaga S, Nagano T, Kobayashi K, Katsurada M, Nakata K, Yamamoto M,
Tachihara M, Kamiryo H, Yokozaki H, Nishimura Y.
Amphiregulin as a Novel Resistance Factor for Amrubicin in Lung Cancer Cells.
Anticancer Res. 2017;37(5):2225-2231.

Yanagita T, Murata Y, Tanaka D, Motegi SI, Arai E, Daniwijaya EW, Hazama D, Washio K, Saito Y,
Kotani T, Ohnishi H, Oldenborg PA, Garcia NV, Miyasaka M, Ishikawa O, Kanai Y, Komori T, Matozaki T.
Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy
JCI Insight. 2017 Jan 12;2(1):e89140.

Tachihara M, Tanaka Y, Zen Y, Nishimura Y.
The Notable Appearance of Pulmonary Artery Intimal Sarcoma on Positron Emission Tomography (PET)/CT
Intern Med. 2017 Nov 1;56(21):2953-2954.

Katsurada N, Suzuki M, Aoshima M, Yaegashi M, Ishifuji T, Asoh N, Hamashige N, Abe M,
Ariyoshi K, Morimoto K; Adult Pneumonia Study Group-Japan.
The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study
BMC Infect Dis. 2017 Dec 6;17(1):755.

Oki T, Tanaka H, Imanishi T, Nakamachi Y, Saegusa J, Kawano S, Hirata KI, Nishimura Y.
Associations between left ventricular diastolic function and right ventricular function in patients with and without preserved left ventricular ejection fraction
Intern Med. 2017 Dec 15;56(24):3333-3339. doi: 10.2169/internalmedicine.6754-15. Epub 2017 Oct 11.

Hori S, Tachihara M, Tamura D, Kobayashi K, Nakata K, Kamiryo H, Sakai Y, Itoh T, Hirose T, Nishimura Y.
Spontaneous Regression of Epithelioid Angiosarcoma in a Young Woman.
J Echocardiogr. 2017 Dec 11. doi: 10.1007/s12574-017-0363-3. [Epub ahead of print]

(Book) Katsurada M, Izumo T. (2017).
Chapter 9 Anesthesia for Bronchoscopy.
Izumo T, Sasada S, Aso T, Nasu K, Arai Y. (Eds.) Respiratory Endoscopy.
Singapore: Springer, pp. 53-58.

(Book) Katsurada M, Izumo T. (2017).
Chapter 22 The Dose and Risk Factors for Radiation Exposure from X-Ray
Fluoroscopy During EBUS-GS for Peripheral Pulmonary Lesions.
Izumo T, Sasada S, Aso T, Nasu K, Arai Y. (Eds.) Respiratory Endoscopy.
Singapore: Springer, pp. 53-58.

経気管支肺生検で診断しえた異所性石灰化症の長期経過観察例
羽間大祐, 立原素子, 國政啓, 堂國良太, 桐生辰徳, 田村大介,
櫨木暢子, 上領博, 小林和幸, 西村善博
気管支学39巻1号 Page64-70, 2017

成人T細胞白血病リンパ腫の診断にセルブロックが有用であった1例
山本正嗣、里内美弥子、高瀬直人、伊藤彰一、河良崇、河野祐子、
浦田佳子、島田天美子、服部剛弘、根來 俊一
気管支学39巻2号 Page165-169, 2017

急性呼吸不全を呈した抗OJ抗体の1例
関谷怜奈、西尾智尋、冨岡洋海、山下修司
日呼吸誌6 (4):235-239,2017

救急病院における喘息患者の治療実態アンケート　兵庫県喘息死ゼロ作戦活動報告2013
堀 朱矢、上領 博、新家治子、櫨木暢子、小林和幸、片山 覚、西村善博
臨床免疫・アレルギー科 68(1): 107-114, 2017

(総説)職業関連呼吸器疾患　じん肺,悪性胸膜中皮腫を中心に概観する
桂田雅大、西村善博
Hospitalist 5巻2号,291-301 2017

(総説)再生検の現状と課題（リキッドバイオプシーを含めて）
安田裕一郎、里内美弥子
日本臨牀 75(7): 1121-1127, 2017

（総説）リキッドバイオプシー
安田裕一郎、里内美弥子
診断と治療 105(11): 1451-1455, 2017.

(書籍)肺がん（12 肺がんの治療 4高齢者肺がんに対する治療 ①非小細胞がん）
山本正嗣　里内美弥子
インフォームドコンセントのための図説シリーズ改訂5版、2017年

(書籍)胸郭の異常（漏斗胸・鳩胸）
西村善博
内科学第11版　矢先義雄編　朝倉書店　861-862, 2017

Koyama H, Ohno Y, Fujisawa Y, Seki S, Negi N, Murakami T, Yoshikawa T,
Sugihara N, Nishimura Y, Sugimura K.
3D lung motion assessments on inspiratory/expiratory thin-section CT:
Capability for pulmonary functional loss of smoking-related COPD in
comparison with lung destruction and air trapping.
Eur J Radiol. 2016 85(2):352-9.

Kunimasa K, Kobayashi K, Inoue N, Nishimura Y.
Haemoptysis as a Presenting Symptom of Thoracic Aneurysm Dissection.
Intern Med. 2016;55(15):2117-8.

Kunimasa K, Tachihara M, Tamura D, Tokunaga S, Nakata K, Hazeki N,
Kamiryo H, Kobayashi K, Sakai Y, Nishimura Y.
Diagnostic utility of additional conventional techniques after
endobronchial ultrasonography guidance during transbronchial biopsy.
Respirology. 2016;21(6):1100-5.

Fukuhara N, Tachihara M, Tanino Y, Saito J, Sato S, Nikaido T, Misa K,
Fukuhara A, Wang X, Ishida T, Onami T, Munakata M.
Cholesteryl palmitate crystals in bronchoalveolar lavage fluid smears as
a possible prognostic biomarker for chronic interstitial pneumonia: A
preliminary study.
Respir Investig. 2016;54(2):109-15.

Takahama T, Sakai K, Takeda M, Azuma K, Hida T, Hirabayashi M, Oguri T,
Tanaka H, Ebi N, Sawa T, Bessho A, Tachihara M, Akamatsu H, Bandoh S,
Himeji D, Ohira T, Shimokawa M, Nakanishi Y, Nakagawa K, Nishio K.　
Detection of the T790M mutation of EGFR in plasma of advanced non-small
cell lung cancer patients with acquired resistance to tyrosine kinase
inhibitors (West Japan oncology group 8014LTR study).
Oncotarget. 2016;7(36):58492-58499.

Rider CF, Yamamoto M, Günther OP, Hirota JA, Singh A, Tebbutt SJ,
Carlsten C.
Controlled diesel exhaust and allergen coexposure modulates microRNA and
gene　expression in humans: Effects on inflammatory lung markers.
J Allergy Clin Immunol. 2016;138(6):1690-1700.

Takase N, Hattori Y, Kiriu T, Itoh S, Kawa Y, Yamamoto M,
Urata Y, Shimada T, Tsujino K, Soejima T, Negoro S, Satouchi M.
Concurrent chemoradiotherapy with cisplatin and S-1 or vinorelbine for patients
with stage III unresectable non-small cell lung cancer: A retrospective study.
Respir Investig. 2016;54(5):334-40.

Terashita T, Kobayashi K, Nagano T, Kawa Y, Tamura D, Nakata K,
Yamamoto M, Tachihara M, Kamiryo H, Nishimura Y.
Administration of JTE013 abrogates experimental asthma by regulating
proinflammatory cytokine production from bronchial epithelial cells.
Respir Res. 2016;17(1):146.

Allergic bronchopulmonary aspergillosis(ABPA)様の画像を呈した
ピーナッツ気管支異物の一例
関谷怜奈，小林和幸，堂國良太，羽間大祐，桐生辰徳，國政啓，田村大介，
立原素子,上領博，西村善博
気管支学38巻6号, 515-520, 2016

(総説)呼吸機能検査でできること
西村善博
呼吸器内科30巻4号, 342-348, 2016

(総説) 診断がつかないせき、対応に困るせき
桂田雅大、西村善博
JOHNS 32巻8号, 941-945, 2016

Asano F, Shinagawa N, Ishida T, Tsuzuku A, Tachihara M, Kanazawa K,
Yamada N, Oizumi S, Moriya H. Virtual Bronchoscopic Navigation Improves
the Diagnostic Yield of Radial-Endobronchial Ultrasound for Peripheral
Pulmonary Lesions with Involved Bronchi on CT.
Intern Med 2015；54: 1021-1025.

Otsuka T, Mori M, Yano Y, Uchida J, Nishino K, KaJi R, Hata A, Hattori
Y, Urata Y, Kaneda T, Tachihara M, Imamura F, Katakami N, Negoro S,
Morita S, Yokota S. Effectiveness of Tyrosine Kinase Inhibitors in
Japanese Patients with Non-small Cell Lung Cancer Harboring Minor
Epidermal Growth Factor Receptor Mutations: Results from a Multicenter
Retrospective Study (HANSHIN Oncology Group 0212).
Anticancer research 2015;35: 3885-3892.

Nishino K, Imamura F, Kumagaia T, Katakami N, Hata A, Okuda C, Urata Y,
Hattori Y, Tachihara M, Yokota S, Nishimura T, Kaneda T, Satouchi M,
Morita S, Negoro S.
A randomized phase II study of bevacizumab in combination with docetaxel
or S-1 in patients with non-squamous non-small-cell lung
cancer previously treated with platinum based chemotherapy (HANSHIN
Oncology Group 0110).
Lung Cancer. 2015; 89 2015:146–153.

Okuma Y, Tanuma J, Kamiryo H, Kojima Y, Yotsumoto M, Ajisawa A, Uehira
T, Nagai H, Takeda Y, Setoguchi Y, Okada S.
A multi-institutional study of clinicopathological features and
molecular epidemiology of epidermal growth factor receptor mutations in
lung cancer patients living with human immunodeficiency virus infection.
J Cancer Res Clin Oncol. 2015 Mar 24.

Kunimasa K, Tachihara M, Terashita T, Nishimura Y
Gradually Enlarging Crazy-paving Appearance.
Intern Med. 2015;54(21):2791-2.

呼吸器抄読会　神戸大学大学院医学研究科内科学講座呼吸器内科学分野
呼吸　34巻1号、120、2015

COPD診療にいかに取り組むか　COPDの診断法と治療
西村善博
兵庫県医師会医学雑誌 第58巻1号 4-6，2015

喘息発作による救急外来受診後の再受診状況の現状と課題
櫨木暢子，小林和幸，船田泰弘，寺田忠之，中谷裕司，岡勝巳，金岡正樹，岸本信康，黒坂文武，田中明，西庵利彦，望月吉郎，八木一之，山田充宏，山本裕之，薄木洋明，大本明義，西村善博
兵庫県医師会医学雑誌　第58巻第1号 44-49，2015

Picture in Clinical
Hematology(No.85)　FDG-PETで両肺にびまん性異常集積を認めた血管内大細胞型B細胞リンパ腫.
阿部緑生，立原素子，植松学，勝浦豊，田中端子，杉野隆，小川一英.
臨床血液2015;56:749.

左上葉腫瘤に対する経気管支生検に加えて，右肺門リンパ節の経気管支穿刺吸引細胞診を行うことで診断し得た同時多発肺癌の1例
高瀬直人，里内美弥子，桐生辰徳，西村春佳，伊藤彰一，内堀健，山本正嗣，奥野恵子，浦田佳子，島田天美子，服部剛弘，根來俊一
気管支学 37巻5号，537-543，2015

気管支擦過細胞診にてアレルギー性気管支肺アスペルギルス症が疑われた1例
寺下智美，立原素子，上原慶一郎，酒井康裕，西村善博
臨床細胞学会，54巻，221-222，2015

Hatakeyama Y, Kobayashi K, Nagano T, Tamura D, Yamamoto M, Tachihara M, Kotani Y, Nishimura Y.
Synergistic effects of pemetrexed and amrubicin in non-small cell lung cancer cell lines: Potential for combination therapy.
Cancer Lett. 2014 Feb 1;343(1):74-9.

Tachihara M, Kobayashi K, Ishikawa Y, Hori S, Tamura D, Otera H, Funada Y, Nishimura Y.
Successful Crizotinib Rechallenge After Crizotinib-induced Interstitial Lung Disease.
Jpn J Clin Oncol. 2014 Aug;44(8):762-4.

Nagano T, Edamatsu H, Kobayashi K, Takenaka N, Yamamoto M, Sasaki N, Nishimura Y, Kataoka T.
Phospholipase Cε, an effector of Ras and Rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma.
PLoS One. In press.

Motoko Tachihara, Takashi Ishida, Naoko Fukuhara, Yayoi Inokoshi, Atsuro Fukuhara, Kazue Saito, Taeko Ishii, Kenya Kanazawa, Yutaka Katsuura, Mitsuru Munakata.
Catheter Spray of Lidocaine: a Randomized Study of Topical Anesthesia for Flexible Bronchoscopy.
JJSRE. 2014;36:359-363.

Hazeki N, Kobayashi K, Shinke H, Yamamoto M, Ohta M, Nishimura Y.
Semipermeable membrane dressings are usable with nicotine transdermal system and do not interfere with nicotine absorption.
Intern Med. 2013;52(24):2743-8.

Sugawara S, Maemondo M, Tachihara M, Inoue A, Ishimoto O, Sakakibara T, Usui K, Watanabe H, Matsubara N, Watanabe K, Kanazawa K, Ishida T, Saijo Y, Nukiwa T.
Randomized phase II trial of uracil/tegafur and cisplatin versus vinorelbine and cisplatin with concurrent thoracic radiotherapy for locally advanced unresectable stage III non-small-cell lung cancer: NJLCG 0601.
Lung cancer 2013;81: 91-96.

Shinke H, Yamamoto M, Hazeki N, Kotani Y, Kobayashi K, Nishimura Y.
Visualized changes in respiratory resistance and reactance along a time axis in smokers: A cross-sectional study.
Respir Investig. 2013 Sep;51(3):166-74.

Tamura D, Arao T, Nagai T, Kaneda H, Aomatsu K, Fujita Y, Matsumoto K, De Velasco MA, Kato H, Hayashi H, Yoshida S, Kimura H, Maniwa Y, Nishio W, Sakai Y, Ohbayashi C, Kotani Y, Nishimura Y, Nishio K.
Slug increases sensitivity to tubulin-binding agents via the downregulation of bIII and bIVa-tubulin in lung cancer cells
Cancer Med. 2013 Apr;2(2):144-54.

Yamamoto M, Singh A, Sava F, Pui M, Tebbutt SJ, Carlsten C.
MicroRNA
expression in response to controlled exposure to diesel exhaust: attenuation by the antioxidant N-acetylcysteine in a randomized crossover study.
Environ Health Perspect. 2013 Jun;121(6):670-5.

Singh A, Yamamoto M, Kam SH, Ruan J, Gauvreau GM, O'Byrne PM, FitzGerald JM, Schellenberg R, Boulet LP, Wojewodka G, Kanagaratham C, De Sanctis JB, Radzioch D, Tebbutt SJ.
Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses.
PLoS One. 2013 Jul 2;8(7):e67907

Sakai Y, Yamasaki T, Kusakabe Y, Kasai D, Kotani Y, Nishimura Y, Itoh T.
Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature.
Multidiscip Respir Med. 2013 Jul 18;8(1):47.

Shinke H, Yamamoto M, Hazeki N, Kotani Y, Kobayashi K, Nishimura Y.
Visualized changes in respiratory resistance and reactance along a time axis in smokers: A cross-sectional study.
Respir Investig. 2013 Sep;51(3):166-74.

Hazeki N, Kobayashi K, Shinke H, Yamamoto M, Ohta M, Nishimura Y
Semipermeable membrane dressings are usable with nicotine transdermal system and do not interfere with nicotine absorption.
Intern. med. In press.

邦文原著論文、総説など
仮想気管支鏡ナビゲーション併用によるTBNAにて確定診断しえた肺MALTリンパ腫の１例.
立原素子, 田村大介, 畠山由起久, 新家治子，堀朱矢, 石川結美子，櫨木暢子，小林和幸, 船田泰弘, 小谷義一, 西村善博
気管支学 in press 2013

特集：呼吸器疾患の診断・治療（Ⅰ）気管支拡張症
德永俊太郎、西村善博
医学と薬学 69巻1号,2013

Kurata T, Hirashima T, Iwamoto Y, Kawaguchi T, Ikeda N, Tsuboi M, Sawa T, Ishiguro T, Aoki T, Kotani Y, Nakagawa K, Fukuoka M.
A phase I/II study of carboplatin plus gemcitabine for elderly patients with advanced non-small cell lung cancer: West Japan Thoracic Oncology Group Trial (WJTOG) 2905.
Lung Cancer. 2012 Jul;77(1):110-5.

Nagano T, Kotani Y, Fujii O, Demizu Y, Niwa Y, Ohno Y, Nishio W, Itoh T, Murakami M, Nishimura Y.
A case of acute exacerbation of idiopathic pulmonary fibrosis after proton beam therapy for non-small cell lung cancer.
Jpn J Clin Oncol. 2012 Oct;42(10):965-9. Epub 2012 Jul 23.

Koyama H, Ohno Y, Nishio M, Takenaka D, Yoshikawa T, Matsumoto S, Nishimura Y, Sugimura K.
Three-dimensional airway lumen volumetry: comparison with bronchial wall area and parenchymal densitometry in assessment of airway obstruction in pulmonary emphysema.
Br J Radiol. 2012 Dec;85(1020):1525-32.

Tachihara M, Nikaido T, Wang X, Ishii T, Saito K, Sekine S, Tanino Y, Ishida T, Munakata M.
Four Cases of Trousseau's Syndrome Associated with Lung Adenocarcinoma.
Intern Med. 2012;51:1099-1102.

Yamamoto M, Singh A, Ruan J, Gauvreau GM, O'Byrne PM, Carlsten CR, FitzGerald JM, Boulet LP, Tebbutt SJ.
Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge.
BMC Genomics. 2012 Nov 21;13:655

Yamamoto M, Nagano T, Okuno K, Nakata K, Takenaka K, Kobayashi K, Ishikawa Y, Sakashita A, Kotani Y, Funada Y, Nishimura Y.
An open-label, prospective clinical study to evaluate the efficacy of prophylactic antibiotics after diagnostic bronchoscopy
Kobe J Med Sci. 2012 Dec 13;58(4):E110-8.

邦文原著論文、総説など
緩和ケアチーム介入によるがん患者QOLの変化についての検討
新家治子， 坂下明大，石橋有希，太田垣加奈子，藤原由佳，五百蔵武士，田宮裕子，小谷義一，向原徹，南博信，西村善博
Palliative Care Research 2012; 7(2): 368-73

1日1回型フェンタニル貼付剤にオピオイド・ローテーションしたがん疼痛症例の検討
坂下明大，新家治子，太田垣加奈子，石橋有希，紀平裕美，打保裕子，五百蔵武士，高野由美子，西村善博
ペインクリニック，33巻，841-846，2012

集検喀痰細胞診で発見された喉頭癌と早期中心型肺癌の細胞像の比較検討
立原素子，神尾淳子，佐藤丈晴，室井祥江，　柴田眞一，森村　豊，石田　卓，棟方　充
臨床細胞学会.2012;51:7-12.

プロクロルペラジンにより横紋筋融解症を来した1例
紀平裕美, 打保裕子, 太田垣加奈子, 坂下明大, 久米学, 平野剛, 西村善博, 平井みどり
日本緩和医療薬学雑誌, 5巻3号, 61-64, 2012

診断に苦慮した原発性心臓腫瘍の1例
堀朱矢，小谷義一，笠井大介，新家治子，河良崇，畠山由記久，山本聡美，大林千穂，西村善博
日本胸部臨床，71巻，292-298，2012

【悪性腫瘍-その合理的な画像診断の進め方】 再発チェックを合理的に行う
には　肺癌
大野良治，関紳一郎，西尾瑞穂，尾西由美子，神山久信，吉川武，松本純明，真庭謙昌，西村善博，杉村和朗
臨床画像，28巻，786-794，2012

喫煙と歯科疾患
櫨木暢子，小林和幸，小谷義一，西村善博
兵庫県歯科医師会機関誌「歯界月報」2012年8月号（733号）

薬剤師に対する喘息患者への吸入指導に対するアンケート調査
堀　朱矢，西村　善博，小林　和幸，深堀　隆，石原　亮介，片山　覚
兵庫県医師会医学雑誌,　 55巻1号,　22－26, 2012

Non-small cell carcinoma: Comparison of postoperative intra- and extrathoracic recurrence assessment capability of qualitatively and/or quantitatively assessed FDG-PET/CT and standard radiological examinations.
Onishi Y, Ohno Y, Koyama H, Nogami M, Takenaka D, Matsumoto K, Yoshikawa T, Matsumoto S, Maniwa Y, Nishimura Y, Sugimura K.
Eur. J. Radiol. 2011 79: 473-479

MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell.
Doi T, Maniwa Y, Tanaka Y, Tane S, Hashimoto S, Ohno Y, Nishio W, Nishimura Y, Ohbayashi C, Okita Y, Hayashi Y, Yoshimura M.
Exp. Mol. Pathol. 2011 90: 91-96

Differentiation of malignant and benign pulmonary nodules with quantitative first-pass 320-detector row perfusion CT versus FDG PET/CT.
Ohno Y, Koyama H, Matsumoto K, Onishi Y, Takenaka D, Fujisawa Y, Yoshikawa T, Konishi M, Maniwa Y, Nishimura Y, Ito T, Sugimura K.
Radiology 2011 258: 599-609

Quantitative bronchial luminal volumetric assessment of pulmonary function loss by thin-section MDCT in pulmonary emphysema patients.
Koyama H, Ohno Y, Yamazaki Y, Onishi Y, Takenaka D, Yoshikawa T, Nishio M, Matsumoto S, Murase K, Nishimura Y, Sugimura K.
Eur. J. Radiol., 2011 81: 384-388

Comparison of capability of dynamic O(2)-enhanced MRI and quantitative thin-section MDCT to assess COPD in smokers.
Ohno Y, Koyama H, Yoshikawa T, Matsumoto K, Aoyama N, Onishi Y, Takenaka D, Matsumoto S, Nishimura Y, Sugimura K.
Eur. J. Radiol. 2011 Mar 8.　[Epub ahead of print]

A metabolomic approach to lung cancer.
Hori S, Nishiumi S, Kobayashi K, Shinohara M, Hatakeyama Y, Kotani Y, Hatano N, Maniwa Y, Nishio W, Bamba T, Fukusaki E, Azuma T, Takenawa T, Nishimura Y, Yoshida M.
Lung Cancer 2011 74: 284-292

Antigen-specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells.
Ishikawa Y, Kobayashi K, Yamamoto M, Nakata K, Takagawa T, Funada Y, Kotani Y. Karasuyama H, Yoshida M, Nishimura Y.
Respir. Res. 2011 10: 42-51

Reduced-dose chest CT with 3D automatic exposure control vs. standard chest CT: Quantitative assessment of emphysematous changes in smokers' lung parenchyma.
Koyama H, Ohno Y, Yamazaki Y, Matsumoto K, Onishi Y, Takenaka D, Yoshikawa T, Nishio M, Matsumoto S, Murase K, Nishimura Y, Sugimura K.
Eur. J. Radiol. 2011 Jun 22. [Epub ahead of print]

Chemotherapy improves thymoma-associated graft-versus- host-disease-like erythroderma.
Nagano T, Kotani Y, Kobayashi K, Tomita N, Nakata K, Sakashita A, Funada Y, Nagai H, Itoh T, Nishimura Y.
BMJ Case Reports 2011 May 10. [Epub ahead of print]

N stage disease in patients with non-small cell lung cancer: Efficacy of quantitative and qualitative assessment with STIR turbo spin-echo imaging, diffusion-weighted MR imaging, and fluorodeoxyglucose PET/CT.
Ohno Y, Koyama H, Yoshikawa T, Nishio M, Aoyama N, Onishi Y, Takenaka D, Matsumoto S, Maniwa Y, Nishio W, Nishimura Y, Itoh T, Sugimura K.
Radiology 2011 261: 605-615

Long-term outcome after multidisciplinary approach for leptomeningeal carcinomatosis in a non-small cell lung cancer patient with poor performance status.
Nagano T, Kotani Y, Kobayashi K, Hatakeyama Y, Hori S, Kasai D, Funada Y, Nishimura H, Kondoh T, Nishimura Y.
Intern. Med. 2011 50: 3019-3022.

Successful erlotinib treatment for a patient with gefitinib-related hepatotoxicity and lung adenocarcinoma refractory to intermittently administered gefitinib.
Nagano T, Kotani Y, Kobayashi K, Katsurada M, Hatakeyama Y, Hori S, Tamura D, Kasai D, Funada Y, Nishimura Y.
Case Reports in Pulmonology 2011, Article ID 812972.

Early diagnosis of health damage in arc welders based on their serum ferritin level.
Sera K, Nishimura Y, Hayashi C, Nishio H.
Open Journal of Internal Medicine 2011 1: 77-79

Comparison of 3-D-visualized respiratory impedance patterns and structural change detected by CT in smokers.
Shinke H, Yamamoto M, Hazeki N, Kobayashi K, Funada Y, Kotani Y, Ohno Y, Nishimura Y.
5th International Workshop for Pulmonary Functional Imaging, 2011

Prevalence of chronic obstructive pulmonary disease in inpatients with cardiovascular disease.
Kawa Y, Kobayashi K, Nakata K, Shinke H, Funada Y, Kotani Y, Nishimura Y.
106th ATS International Conference, 2011

Relevance between respiratory impedance pattern and structural changes in smoking-induced expiratory flow limitation.
Shinke H, Yamamoto M, Hazeki N, Kawa Y, Kobayashi K, Funada Y, Kotani Y, Nishimura Y.
106th ATS International Conference, 2011

Crucial role of phospholipase Cε in the development of asthma in mice.
Nagano T, Edamatsu H, Kobayashi K, Nishimura Y, Kataoka T.
31st ERS Annual Congress, 2011

Clinical utility of EGFR gene mutation analysis with cytological materials from bronchoscopy not histological materials.
Nakata K, Kotani Y, Hatakeyama Y, Tomita N, Hazeki N, Sakashita A, Kobayashi K, Funada Y, Nishimura Y.
31st ERS Annual Congress, 2011

Ohno Y, Koyama H, Yoshikawa T, Nishio M, Aoyama N, Onishi Y, Takenaka D, Matsumoto S, Maniwa Y, Nishio W, Nishimura Y, Itoh T, Sugimura K.
N stage disease in patients with non-small cell lung cancer:
Efficacy of quantitative and qualitative assessment with STIR turbo spin-echo imaging, diffusion-weighted MR imaging, and fluorodeoxyglucose PET/CT.
Radiology 2011 261: 605-615

Tachihara M, Misa K, Uematsu M, Minemura H, Katsuura Y, Ishida T, Munakata M. Increase of Ascites and Pleural Effusion　Misleading Assessment of Antitumor　Response to Erlotinib in Adenocarcinoma of the Lung.
J Clin Oncol. 2011;29:e675-7.

邦文原著論文、総説など
肺胞洗浄液のRT-PCR検査により診断しえた重症新型インフルエンザA（H1N1）2009ウイルス肺炎の1例
桂田直子，大西尚，山本聡美，木南佐織，西馬照明，西村善博，荒川創一
感染症学雑誌，85巻，172-175，2011

肺原発筋上皮癌の1例
奥野恵子，小林和幸，吉村雅裕，大野良治，大林千穂，西村善博
肺癌，51巻，77-83，2011

気管挿管の関与が考えられた喉頭炎症性肉芽の1例
奥野恵子，杉村春佳， 小林和幸，小谷義一，西村善博
気管支学，33巻，306-310，2011

急速な増大を認めた小細胞型悪性胸膜中皮腫の1例
石川結美子，小林和幸，船田泰弘，山本正嗣，堀朱矢，新家治子，畠山由記久，坂下明大，小谷義一，西村善博，大林千穂
気管支学，33巻，435-442，2011

兵庫県喘息死ゼロ作戦－2011年実績報告と今後の展開－
西村善博，小林和幸，片山覚
兵庫県医師会医学雑誌，54巻，32-35, 2011

腸管出血性大腸菌感染症
笠井大介　　
臨床医のための消化管内視鏡アトラス　医薬ジャーナル社　2011年

局所再発を繰り返し、外科切除にて混合型小細胞肺癌と診断した1例
立原素子, 渡邉香奈, 横内浩, 鈴木弘行, 石田卓, 棟方充
肺癌. 2011;51:820-824.

Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1 in a mouse model of non-small cell lung cancer.
Nagano T, Yasunaga M, Goto K, Kenmotsu H, Koga Y, Kuroda J, Nishimura Y, Sugino T, Nishiwaki Y, Matsumura Y.
Int J Cancer. 2010 Dec 1;127(11):2699-706.

The antitumor activity of NK012, an SN-38-incorporating micelle, in combination with bevacizumab against lung cancer xenografts.
Kenmotsu H, Yasunaga M, Goto K, Nagano T, Kuroda J, Koga Y, Takahashi A, Nishiwaki Y, Matsumura Y.
Cancer. 2010 Oct 1;116(19):4597-604.

The inhibitory effects of intravenous administration of rabbit immunoglobulin G on airway inflammation are dependent upon Fcγ receptor IIb on CD11c(+) dendritic cells in a murine model.
Yamamoto M, Kobayashi K, Ishikawa Y, Nakata K, Funada Y, Kotani Y, Masuda A, Takai T, Azuma T, Yoshida M, Nishimura Y.
Clin Exp Immunol. 2010 Sep 1. doi: 10.1111/j.1365-2249.2010.04243.x. [Epub ahead of print]

Bortezomib potentially inhibits cellular growth of vascular endothelial cells through suppression of G2/M transition.
Tamura D, Arao T, Tanaka K, Kaneda H, Matsumoto K, Kudo K, Aomatsu K, Fujita Y, Watanabe T, Saijo N, Kotani Y, Nishimura Y, Nishio K.
Cancer Sci. 2010 Jun;101(6):1403-8. Epub 2010 Mar 15.

A case of hard metal lung disease resembling a hypersensitive pneumonia in radiological images.
Okuno K, Kobayashi K, Kotani Y, Ohnishi H, Ohbayashi C, Nishimura Y.
Intern Med. 2010;49(12):1185-9. Epub 2010 Jun 15.

Non-small cell carcinoma: Comparison of postoperative intra- and extrathoracic recurrence assessment capability of qualitatively and/or quantitatively assessed FDG-PET/CT and standard radiological examinations.
Onishi Y, Ohno Y, Koyama H, Nogami M, Takenaka D, Matsumoto K, Yoshikawa T, Matsumoto S, Maniwa Y, Nishimura Y, Sugimura K.
Eur J Radiol. 2010 May 21. [Epub ahead of print]

Randomized phase II study of two different schedules of gemcitabine and oral S-1 in chemo-naïve patients with advanced non-small cell lung cancer.
Satouchi M, Kotani Y, Katakami N, Shimada T, Urata Y, Yoshimura S, Funada Y, Hata A, Ando M, Negoro S.
J Thorac Oncol. 2010 May;5(5):696-701

The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner.
Nakata K, Kobayashi K, Ishikawa Y, Yamamoto M, Funada Y, Kotani Y, Blumberg RS, Karasuyama H, Yoshida M, Nishimura Y.
Biochem Biophys Res Commun. 2010 Apr 30;395(2):238-43. Epub 2010 Apr 1.

Sphingosine kinase 1 regulates mucin production via ERK phosphorylation.
Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y, Jahangeer S, Nakamura S, Nishimura Y.
Pulm Pharmacol Ther. 2010 Feb;23(1):36-42. Epub 2009 Oct 14.

邦文原著
低用量オキシコドンからフェンタニルパッチへのオピオイド・ローテーションの安全性の検討
坂下明大, 石川結美子, 奥野恵子, 櫨木暢子, 玉尾夏実, 河野祐子, 小林和幸, 船田泰弘, 小谷義一, 西村善博
ペインクリニック　31巻5号 Page649-653, 2010

邦文その他
【アレルギー疾患と脂質メディエーター】 スフィンゴシン1リン酸代謝と気管支喘息
西馬照明, 西村善博
臨床免疫・アレルギー科　54巻1号 Page65-71, 2010

【睡眠と生活習慣病】 睡眠と急性冠症候群
櫨木暢子, 小林和幸, 西村善博, 平田健一
成人病と生活習慣病　40巻4号 Page395-397, 2010

【分子標的治療薬の副作用マネージメント】II-B-3．循環器障害
永野達也、後藤功一
南江堂　in press, 2010

家族性肺胞低換気症候群
船田泰弘
呼吸, 29(2) : 163-166, 2010.

国内学会
胸腔鏡下に切除した後縦隔発生Castleman病の1例
橋本章太郎, 真庭謙昌, 西尾渉, 吉村雅裕, 船田泰弘, 小谷義一, 西村善博, 竹中大祐, 大野良治, 上原慶一郎, 伊藤智雄
第91回日本肺癌学会関西支部会　2010年1月30日　大津

メタボロミクスを用いた肺癌バイオマーカーの探索
岡本朱矢，小林和幸，山本正嗣，船田泰弘，小谷義一，西村善博，西海信，篠原正和，吉田優
第６回呼吸器バイオマーカー研究会　2010年03月27日　東京

新型インフルエンザ 簡易検査では繰り返し陰性であったが，肺胞洗浄液のPCR検査により診断しえた重症新型インフルエンザウイルス肺炎の1例
大西尚, 小澤一之, 山本聡美, 岩佐直子, 木南佐織, 西馬照明, 西村善博, 荒川創一
第84回日本感染症学総会・学術講演会　2010年4月6日　京都

アレルギー性気道炎症におけるFcRnの役割
中田恭介, 小林和幸, 石川結美子, 岡本朱矢, 山本正嗣, 坂下明大, 船田泰弘, 小谷義一, 吉田優, 西村善博
第50回日本呼吸器学会学術講演会　2010年4月24日　京都

III期非小細胞肺癌に対する放射線同時併用毎週投与イリノテカン(I)+カルボプラチン(C)・パクリタキセル(P)+Cの第III相無作為化比較試験(WJTOG 0105)
横田総一郎, 工藤新三, 樋田豊明, 浅見和弘, 坂英雄, 牛島淳, 小谷義一, 後藤功, 高山浩一, 川瀬一郎, 中野孝司, 木村弘, 西村恭昌, 中川和彦
第50回日本呼吸器学会学術講演会　2010年4月24日　京都

EGFR変異を有する非小細胞肺癌(NSCLC)に対するゲフィチニブ(G)とシスプラチン(C)+ドセタキセル(D)の比較第III相試験(WJTOG3405)
平島智徳, 光冨徹哉, 浅見和弘, 齋藤博, 菓子井達彦, 横山彰仁, 森永亮太郎, 山口悦郎, 小谷義一, 阿部直, 伊達洋至, 木村弘, 中川和彦
第50回日本呼吸器学会学術講演会　2010年4月24日　京都

メタボローム解析を用いた肺癌バイオマーカーの探索
岡本朱矢, 小林和幸, 西海信, 畠山由記久, 河良崇, 永野達也, 石川結美子, 中田恭介, 倉本衣美, 櫨木暢子, 山本正嗣, 坂下明大, 船田泰弘, 小谷義一, 橋本章太郎, 真庭謙昌, 西尾渉, 篠原正和, 吉田優, 西村善博
第50回日本呼吸器学会学術講演会　2010年4月25日　京都

喫煙者における末梢気道病変のモストグラフによる評価
山本正嗣, 桂田雅大, 小林和幸, 櫨木暢子, 坂下明大, 船田泰弘, 小谷義一, 西村善博
第50回日本呼吸器学会学術講演会　2010年4月25日　京都

閉塞型睡眠時無呼吸症候群におけるモストグラフによる呼吸抵抗の解析
櫨木暢子, 山本正嗣, 倉本衣美, 桂田雅大, 小林和幸, 坂下明大, 船田泰弘, 小谷義一, 西村善博
第50回日本呼吸器学会学術講演会　2010年4月25日　京都

Bacillus属検出患者の背景調査と感染危険因子の探索
山下和彦, 阿部泰尚, 中村正邦, 田中健太, 植田貴史, 大松秀明, 平野剛, 森岡一郎, 中野雄造, 八幡眞理子, 瀬尾靖, 吉田弘之, 李宗子, 西村善博, 平井みどり, 荒川創一
題58回日本化学療法学会総会　2010年6月2日　長崎

悪性腫瘍患者における緩和ケアニーズのスクリーニングに関する検討
坂下明大，石橋有希，太田垣加奈子，藤原由佳，五百蔵武士，田宮裕子，西村善博，小谷義一，向原徹，南博信
第15回日本緩和医療学会学術大会　2010年6月19日　東京

Snailに誘導される上皮間葉移行は肺癌のチュブリン作用系抗癌剤の感受性を規定する
田村大介　荒尾徳三　永井知行　青松圭一　金田裕靖　松本和子　工藤可苗
坂井和子　木村英晴　藤田至彦　古田一行 　西条長宏　西尾和人
第14回日本がん分子標的治療学会学術集会　2010年7月8日　東京

GVHD様反応による紅皮症を呈した浸潤性胸腺腫の1例
冨田菜々子，中田恭介，畠山由記久，永野達也，山本聡美，櫨木暢子，船田泰弘，小谷義一，西村善博
第75回日本呼吸器学会近畿地方会　2010年7月17日

びまん性粒状陰影と空洞性病変を伴った粘液産生型肺腺癌の1例
山本聡美，櫨木暢子，冨田菜々子，中田恭介，船田泰弘，小谷義一, 西村善博
第75回日本呼吸器学会近畿地方会　2010年7月17日

ニコチンパッチの皮膚障害に対するテガダームの有用性の検討
櫨木暢子，小林和幸，船田泰弘，小谷義一　西村善博
第192回日本内科学会近畿地方会　2010年9月11日　大阪

SNAI2-mediated epithelial mesenchymal transition increases the drug sensitivity to tubulin binding agents in lung cancer
Daisuke Tamura Tokuzo Arao, Tomoyuki Nagai, Kazuyuki Furuta, Kazuko Sakai, Kanae Kudo, Hiroyasu Kaneda, Keiichi Aomatsu, Yoshihiko Fujita, Kazuko Matsumoto, Nagahiro Saijo, and Kazuto Nishio
第69回日本癌学会学術総会　2010年9月23日　大阪

緩和ケアチームによる薬物療法がもたらす患者QOLへの影響
―EORTC　QLQ－C15－PALを用いた臨床研究―
打保裕子，五百蔵武士，紀平裕美，坂下明大，石橋有希，太田垣加奈子，藤原由佳，槇本博雄，平野剛，西村善博，平井みどり
第4回緩和医療薬学会年会　2010年9月26日　鹿児島

小児緩和ケアにおける疼痛評価とそれに基づく薬物療法との関係
〜仙骨原発primitive neuroectodermal tumor症例に対する介入からみえた緩和ケアチーム薬剤師の課題〜
紀平裕美，打保裕子，五百蔵武士，太田垣加奈子，石橋有希，藤原由佳，坂下明大，久米学，平野剛，西村善博，平井みどり
第4回緩和医療薬学会年会　2010年9月26日　鹿児島

がん疼痛治療中にプロクロルペラジンが原因と考えられる横紋筋融解症をきたした一例
坂下明大
JPAP第14回ペインカンファレンス　10月2日　大阪

国際学会
Intratracheal instillation of antigen specific IgG inhibits an allergic airway inflammation via Fcγ receptor IIB on dendritic cells
Yumiko Ishikawa, Kazuyuki Kobayashi, Masatsugu Yamamoto, Kyosuke Nakata, Emi Kuramoto, Yasuhiro Funada, Yoshikazu Kotani, Masaru Yoshida, Yoshihiro Nishimura
XXI World Allergy Congress 2009年12月9日　Buenos Aires, República Argentina

Snail and slug-mediated epithelial mesenchymal transition in lung cancer cells
Daisuke Tamura Tokuzo Arao, Tomoyuki Nagai, Kazuyuki Furuta, Kazuko Sakai, Kanae Kudo, Hiroyasu Kaneda, Keiichi Aomatsu, Yoshihiko Fujita, Kazuko Matsumoto, Yoshikazu Kotani, Yoshihiro Nishimura, Nagahiro Saijo, Kazuto Nishio
101st American Association for Cancer Research annual meeting 2010年4月20日　 Washington DC, USA

To develop the biomaker of lung cancer by the detection of metabolites expression pattern.
Suya Okamoto, Shin Nishiumi, Yukihisa Hatakeyama, Nobuko Hazeki, Yumiko Ishikawa, Kazuyuki Kobayashi, Masakazu Shinohara, Masaru Yosida, Yoshihiro Nishimura.
ATS 2010 International Conference, 2010年5月17日, New Orleans, USA

The role of FcRn in the allergic airway inflammation
Kyosuke Nakata, Kazuyuki Kobayashi, Yumiko Ishikawa, Suya Okamoto, Masatsugu Yamamoto, Yasuhiro Funada, Yoshikazu Kotani, Masaru Yoshida, Yoshihiro Nishimura
ATS 2010 International Conference, May 17, 2010 New Orleans, LA

The difference between intravenous and intratracheal delivery of sphingosine kinase inhibitor in asthmatic mice models
Yoshitaka Kawa, Teruaki Nishiuma, Kazuyuki Kobayashi, Yasuhiro Funada, Yoshikazu Kotani, Yoshihiro Nishimura
ATS 2010 International Conference, 2010年5月17日, New Orleans, USA

Therapeutic mechanism of intravenous IgG and inhibitory Fc receptor on CD11c+ dendritic cells in murine asthma model
Masatsugu Yamamoto, Kazuyuki Kobayashi, Yumiko Ishikawa, Kyosuke Nakata, Yasuhiro Funada, Yoshikazu Kotani, Yoshihiro Nishimura
2010 Korea-Japn Joint Allergy Symposium　2010年5月28日, Seoul, Korea

Visualization of variance of respiratory impedance in smokers and COPD
Masatsugu Yamamoto, Kazuyuki Kobayashi, Nobuko Hazeki, Emi Kuramoto, Yasuhiro Funada, Yoshikazu Kotani, Yoshihiro Nishimura
ERS 2010，2010年9月19日　Barcelona, Spain

Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1.
T. Nagano, M. Yasunaga, K. Goto, H. Kenmotsu, Y. Koga, J. Kuroda, Y. Nishimura, T. Sugino, Y. Nishiwaki, Y. Matsumura
2010 ASCO Annual Meeting, 2010年6月4日　Chicago, USA

Otera H, Ishida T, Nishiuma T, Kobayashi K, Kotani Y, Yasuda T, Kundu RK, Quertermous T, Hirata K, Nishimura Y.
Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration.
Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L594-602. Epub 2009 Jan 23.

Kuramoto E, Nishiuma T, Kobayashi K, Yamamoto M, Kono Y, Funada Y, Kotani Y, Sisson TH, Simon RH, Nishimura Y.
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.
Am J Physiol Lung Cell Mol Physiol. 2009 Mar;296(3):L337-46. Epub 2008 Dec 19.

Maniwa Y, Yoshimura M, Takata M, Nishimura Y, Ohno Y.
Effective chemotherapy based on a chemosensitivity test for malignant pleural mesothelioma.
Ann Thorac Cardiovasc Surg. 2008 Oct;14(5):319-21.

Yamamoto M, Nishiuma T, Kobayashi K, Maniwa Y, Sakashita A, Funada Y, Kotani Y, Nishimura Y.
Rad9 is upregulated and plays protective roles in an acute lung injury model.
Biochem Biophys Res Commun. 2008 Nov 21;376(3):590-4. Epub 2008 Sep 20.

Sakashita A, Nishimura Y, Nogami M, Kuramoto E, Kono Y, Yamamoto M, Tamao N, Ohtera H, Kobayashi K, Funada Y, Nishiuma T, Kotani Y, Ohno Y.
Diffuse periairway thickening in patients with Mikulicz disease.
J Thorac Imaging. 2008 Aug;23(3):213-5.

Kuramoto E, Kinami S, Ishida Y, Shiotani H, Nishimura Y.
Continuous positive nasal airway pressure decreases levels of serum amyloid A and improves autonomic function in obstructive sleep apnea syndrome.
Int J Cardiol. 2008 Jun 25. [Epub ahead of print]

Ohno Y, Koyama H, Takenaka D, Nogami M, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K.
Dynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules.
J Magn Reson Imaging. 2008 Jun;27(6):1284-95.

Koyama H, Ohno Y, Kono A, Takenaka D, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K.
Quantitative and qualitative assessment of non-contrast-enhanced pulmonary MR imaging for management of pulmonary nodules in 161 subjects.
Eur Radiol. 2008 Oct;18(10):2120-31. Epub 2008 May 6.

Nishiuma T, Nishimura Y, Okada T, Kuramoto E, Kotani Y, Jahangeer S, Nakamura SI.
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.
Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1085-93. Epub 2008 Mar 21.

Ohno Y, Iwasawa T, Seo JB, Koyama H, Takahashi H, Oh YM, Nishimura Y, Sugimura K.
O2-enhanced MRI vs. CT: Multi-center Study for the Clinical Stage Classification of Smoking-related COPD.
Am J Respir Crit Care Med. 2008 May 15;177(10):1095-102. Epub 2008 Feb 14.

Kono Y, Nishiuma T, Nishimura Y, Kotani Y, Okada T, Nakamura S, Yokoyama M.
Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta1.
Am J Respir Cell Mol Biol. 2007;37(4):395-404.

Sakashita A, Nishimura Y, Nishiuma T, Takenaka K, Kobayashi K, Kotani Y, Yokoyama M.
Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.
Eur J Pharmacol. 2007;571(1):62-71.

Takeda T, Hattori N, Tokuhara T, Nishimura Y, Yokoyama M, Miyake M.
Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model.
Cancer Res. 2007;67(4): 1744-9.

Shimada T, Nishimura Y, Nishiuma T, Rikitake Y, Hirase T, Yokoyama M.
Adenoviral transfer of rho family proteins to lung cancer cells ameliorates cell proliferation and motility and increases apoptotic change.
Kobe J Med Sci. 2007;53(3):125-34.

Ohno Y, Koyama H, Takenaka D, Nogami M, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K.
Dynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules.
J Magn Reson Imaging. 2008 Jun;27(6):1284-95.

Ohno Y, Koyama H, Nogami M, Takenaka D, Yoshikawa T, Yoshimura M, Kotani Y, Nishimura Y, Higashino T, Sugimura K.
Whole-body MR imaging vs. FDG-PET: comparison of accuracy of M-stage diagnosis for lung cancer patients.
J Magn Reson Imaging. 2007;26(3):498-509.

Ohno Y, Koyama H, Takenaka D, Nogami M, Kotani Y, Nishimura Y, Yoshimura M, Yoshikawa T, Sugimura K.
Coregistered ventilation and perfusion SPECT using krypton-81m and Tc-99m-labeled macroaggregated albumin with multislice CT utility for prediction of postoperative lung function in non-small cell lung cancer patients.
Acad Radiol. 2007;14(7):830-8.

Takeda T, Nishimura Y, Tsuchiya T, Nakata K, Takenaka K, Nakata H, Yokoyama M.
A large abdominal wall mass as an initial manifestation of malignant mesothelioma.
Am J Med Sci. 2007;333(4):218-20.

Takenaka K, Nishimura Y, Nishiuma T, Sakashita A, Yamashita T, Kobayashi K, Satouchi M, Ishida T, Kawashima S, Yokoyama M.
Ventilator-induced lung injury is reduced in transgenic mice that overexpress endothelial nitric oxide synthase.
Am J Physiol Lung Cell Mol Physiol. 2006;290(6):L1078-86.

Kobayashi K, Nishimura Y, Shimada T, Yoshimura S, Funada Y, Satouchi M, Yokoyama M.
Effect of continuous positive airway pressure on soluble CD40 ligand in patients with obstructive sleep apnea syndrome.
Chest. 2006;129(3):632-7.

Kobayashi K, Nishimura Y, Yamashita T, Nishiuma T, Satouchi M, Yokoyama M.
The effect of overexpression of endothelial nitric oxide synthase on eosinophilic lung inflammation in a murine model.
Int Immunopharmacol. 2006;6(7):1040-52.

Yoshimura S, Nishimura Y, Nishiuma T, Yamashita T, Kobayashi K, Yokoyama M.
Overexpression of nitric oxide synthase by the endothelium attenuates bleomycin-induced lung fibrosis and impairs MMP-9/TIMP-1 balance.
Respirology. 2006;11(5):546-56.

Nakajima T, Nishimura Y, Nishiuma T, Kotani Y, Nakata H, Yokoyama M.
Cough sensitivity in pure cough variant asthma elicited using continuous capsaicin inhalation.
Allergol Int. 2006;55(2):149-55.

Maniwa Y, Yoshimura M, Bermudez VP, Okada K, Kanomata N, Ohbayashi C, Nishimura Y, Hayashi Y, Hurwitz J, Okita Y.
His239Arg SNP of HRAD9 is associated with lung adenocarcinoma.
Cancer. 2006;106(5):1117-22.

Takeda T, Nishimura Y, Satouchi M, Kamiryo H, Takenaka K, Kasai D, Urata Y, Kobayashi K, Shimada T, Yoshimura S, Nishiuma T, Yokoyama M.
Usefulness of the oximetry test for the diagnosis of sleep apnea syndrome in Japan.
Am J Med Sci. 2006;331(6):304-8.

Kitazawa R, Kitazawa S, Nishimura Y, Kondo T, Obayashi C.
Lung carcinosarcoma with liposarcoma element: autopsy case.
Pathol Int. 2006;56(8):449-52.

Nakajima T, Nishimura Y, Nishiuma T, Kotani Y, Funada Y, Nakata H, Yokoyama M.
Characteristics of patients with chronic cough who developed classic asthma during the course of cough variant asthma: a longitudinal study.
Respiration. 2005;72(6):606-11.

Urata Y, Nishimura Y, Hirase T, Yokoyama M.
Sphingosine 1-phosphate induces alpha-smooth muscle actin expression in lung fibroblasts via Rho-kinase.
Kobe J Med Sci. 2005;51(1-2):17-27.

Sakaeda T, Okamura N, Gotoh A, Shirakawa T, Terao S, Morioka M, Tokui K, Tanaka H, Nakamura T, Yagi M, Nishimura Y, Yokoyama M, Okumura K.
EGFR mRNA is upregulated, but somatic mutations of the gene are hardly found in renal cell carcinoma in Japanese patients.
Pharm Res. 2005;22(10):1757-61.

Higashino T, Ohno Y, Takenaka D, Watanabe H, Nogami M, Ohbayashi C, Yoshimura M, Satouchi M, Nishimura Y, Fujii M, Sugimura K.
Thin-section multiplanar reformats from multidetector-row CT data: utility for assessment of regional tumor extent in non-small cell lung cancer.
Eur J Radiol. 2005;56(1):48-55.

Ohno Y, Hatabu H, Higashino T, Nogami M, Takenaka D, Watanabe H, Van Cauteren M, Yoshimura M, Satouchi M, Nishimura Y, Sugimura K.
Oxygen-enhanced MR imaging: correlation with postsurgical lung function in patients with lung cancer.
Radiology. 2005;236(2):704-11.

Funada Y, Nishimura Y, Yokoyama M.
Imbalance of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 is associated with pulmonary emphysema in Klotho mice.
Kobe J Med Sci. 2004;50(3-4):59-67.

Ohno Y, Hatabu H, Takenaka D, Higashino T, Watanabe H, Ohbayashi C, Yoshimura M, Satouchi M, Nishimura Y, Sugimura K.
Metastases in mediastinal and hilar lymph nodes in patients with non-small cell lung cancer: quantitative and qualitative assessment with STIR turbo spin-echo MR imaging.
Radiology. 2004;231(3):872-9.

Ohno Y, Hatabu H, Higashino T, Takenaka D, Watanabe H, Nishimura Y, Yoshimura M, Sugimura K.
Dynamic perfusion MRI versus perfusion scintigraphy: prediction of postoperative lung function in patients with lung cancer.
AJR Am J Roentgenol. 2004;182(1):73-8.

Murakami Y, Kanazawa K, Okuno K, Maekawa S, Matsuda Y, Miyamoto Y, Nishimura Y, Kanomata N, Ohbayashi C, Hashimoto M, Akita H.
High-grade neuroendocrine carcinoma of the lung presenting an unusual spread mimicking pleural mesothelioma associated with dermatomyositis.
Am J Med Sci. 2004;327(4):227-30.

Tsuchiya T, Nishimura Y, Nishiuma T, Kotani Y, Funada Y, Yoshimura S, Yokoyama M.
Airway remodeling of murine chronic antigen exposure model.
J Asthma. 2003;40(8):935-44.