教授 鈴木　聡
Professor　Akira Suzuki

履　　歴

出身／京都市

昭和60年3月

秋田大学医学部医学科　卒業

昭和60年6月

京都大学医学部附属病院内科研修医

昭和61年6月

福井赤十字病院内科医員

昭和62年6月

大阪府済生会中津病院内科医員

平成4年3月

京都大学医学部大学院医学研究科内科専攻（第二内科／井村裕夫教授）卒業

平成4年5月

神戸市立中央市民病院　免疫血液内科　副医長

平成5年7月

Ontario Cancer Institute/ Toronto University ポスドク (Dr.Tak Wah Mak教授)

平成10年9月

東北大学加齢医学研究所病態臓器構築研究分野講師(福本学教授）

平成11年8月

大阪大学微生物病研究所遺伝子動態研究分野講師 (仲野徹教授）

平成13年9月

秋田大学医学部生化学第二講座教授

平成15年4月

改組のため秋田大学医学部構造機能医学講座分子医科学分野と名称変更

平成17年4月

21世紀COEプログラム・リーダー兼任（～平成19年3月）
秋田大学バイオサイエンス教育研究センター・センター長兼任（～平成19年7月）

平成19年7月

九州大学生体防御医学研究所ゲノム機能制御学部門発生工学分野教授
九州大学生体防御医学研究所 発生工学実験室長（兼任）

平成20年4月

改組のため九州大学生体防御医学研究所ゲノム機能制御学部門ゲノム腫瘍学分野と名称変更

平成28年4月

神戸大学大学院医学研究科 分子細胞生物学 教授

○資格／

日本内科学会認定医・専門医

○所属学会等／

日本癌学会（評議員）、日本生化学会（評議員）、日本血液学会（評議員）、日本脂質生化学会（幹事）、日本免疫学会、日本分子生物学会、日本肝臓学会、日本内科学会、日本内科学会専門医会、日本プロテインホスファターゼ研究会（世話人）

○その他／

Cancer Science associate editor（2011.12～)

原　　著

1. Dai Y, Kawaguchi T, Nishio M, Otani J, Tashiro H, Terai Y, Sasaki R, Maehama T, Suzuki A
   The TIGD5 gene located in 8q24 and frequently amplified in ovarian cancers is a tumor suppressor
   Genes to Cells, 2022, in press. doi: 10.1111/gtc.12979
2. Shiraishi Y, Maehama T, Nishio M, Otani J, Hikasa H, Mak TW, Sasaki T, Honma T, Kondoh Y, Osada H, Yoshida M, Fujisawa M, Suzuki A
   N-(3,4-dimethoxyphenethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine inhibits bladder cancer progression by suppressing YAP1/TAZ
   Genes to Cells, 2022, in press. doi: 10.1111/gtc.12979
3. Soyama H, Nishio M, Otani J, Sakuma T, Takao S, Hara S, Masuda T, Mimori K, Toyokuni S, Lydon JP, Nakao K, Nishina H, Fukumoto T, Maehama T, Suzuki A
   Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers
   Proc Natl Acad Sci U S A, 19;119(29):e2123134119, 2022 doi: 10.1073/pnas.2123134119.
4. Uemura S, Yamashita M, Aoyama K, Yokomizo-Nakano T, Oshima M, Nishio M, Masuko M, Takizawa J, Sone H, Yamada Y, Suzuki A, Iwama A
   YAP1/TAZ activity maintains vascular integrity and organismal survival
   Biochem Biophys Res Commun, 3;619:117-123.2022 doi:10.1016/j.bbrc.2022.06.050.
5. Morioka S, Nakanishi H, Yamamoto T, Hasegawa J, Tokuda E, Hikita T, Sakihara T, Kugii Y, Oneyama C, Yamazaki M, Suzuki A, Sasaki J, Sasaki T
   A mass spectrometric method for in-depth profiling of phosphoinositide regioisomers and their diseaseassociated regulation
   Nature Communications, 13(1):83.2022 doi: 10.1038/s41467-021-27648-z.
6. Nakatani K, Maehama T, Nishio N, Otani J, Yamaguchi K, Fukumoto M, Hikasa H, Hagiwara S, Nishina H, Mak TW, Honma T, Kondoh Y, Osada H, Yoshida M, Suzuki A
   Alantolactone is a natural product that potently inhibits YAP1/TAZ via promotion of ROS accumulation
   Cancer Science, 112(10):4303-4316. 2021 doi: 10.1111/cas.15079
7. Miyachi Y, Nishio M, Otani J, Matsumoto S, Kikuchi A, Mak TW, Maehama T, Suzuki A
   TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands
   Genes to Cells, 26(9):714-726. 2021 doi: 10.1111/gtc.12879
8. Ooshio T, Yamamoto M, Fujii K, Xin B, Watanabe K, Goto M, Okada Y, Suzuki A, Penninger JM, Nishina H, Nishikawa Y
   Hepatocyte Mitogen-Activated Protein Kinase Kinase 7 Contributes to Restoration of the Liver Parenchyma Following Injury in Mice
   Hepatology 73(6):2510-2526, 2021 doi: 10.1002/hep.31565.
9. Nishio M, To Y, Maehama T, Aono Y, Otani J, Hikasa H, Kitagawa A, Mimori K, Sasaki T, Nishina H, Toyokuni S, Lydon J, Nakao K, Mak TW, Kiyono T, Katabuchi H, Tashiro H, Suzuki A
   Endogenous YAP1 activation Drives Immediate Onset of Cervical Carcinoma in Situ in Mice
   Cancer Science　111(10):3576-3587, 2020
10. Ishihara E, Nagaoka Y, Okuno T, Kofuji S, Ishigami-Yuasa M, Kagechika H, Kamimura K, Terai S, Yokomizo T, Sugimoto Y, Fujita Y, Suzuki A, Nishina H
    Prostaglandin E2 and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition
    Genes Cells.25(3):197-214. 2020
11. Omori H, Nishio M, Masuda M, Miyachi Y, Ueda F, Nakano T, Sato K, Mimori K, Taguchi K, Hikasa H, Nishina H, Tashiro H, Kiyono T, Mak TW, Nakao K, Nakagawa T, Maehama T, Suzuki A
    YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma
    SCIENCE ADVANCES.18;6(12):eaay3324. 2020
12. Kato W, Nishio M, To Y, Togashi H, Mak TW, Takada H, Ohga S, Maehama T, Suzuki A
    MOB1 regulates thymocyte egress and T-cell survival in mice in a YAP1-independent manner
    Genes Cells. 24(7):485-495. 2019
13. Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D, Kakeji Y, Suzuki A, Dalerba P, Shimono Y
    miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells
    Cancer Res. 79(20):5151-5158, 2019
14. Nishio M, Miyachi Y, Otani J, Tane S, Omori H, Ueda F, Togashi H, Sasaki T, Mak TW, Nakao K, Fujita Y, Nishina H, Maehama T, Suzuki A
    Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency
    FASEB J. 33, 5548, 2019
15. Uegaki M, Kita Y, Shirakawa R, Teramoto Y, Kamiyama Y, Saito R, Yoshikawa T, Sakamoto H, Goto T, Akamatsu S, Yamasaki T, Inoue T, Suzuki A, Horiuchi H, Ogawa O, Kobayashi T
    Downregulation of RalGTPase-activating protein promotes invasion of prostatic epithelial cells and progression from intraepithelial neoplasia to cancer during prostate carcinogenesis
    Carcinogenesis, 40(12):1535-1544, 2019
16. Li Y, Kobayashi K, Murayama K, Kawahara K, Shima Y, Suzuki A, Tani K, Takahashi A
    FEAT enhances INSL3 expression in testicular Leydig cells
    Genes to Cells, 23(11):952-962, 2018
17. Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, Nishina H, Akiyama H, Mak TW, Makii Y, Saito T, Yasoda A, Tsumaki N, Suzuki A
    Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEADs-dependent repression of SOX9
    DEVELOPMENT 145(6), pii: dev159244, 2018
18. Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H
    YAP determines the cell fate of injured mouse hepatocytes in vivo
    NATURE COMMUNICATIONS 8:16017, 2017
19. Nambara S, Masuda T, Nishio M, Kuramitsu S, Tobo T, Ogawa Y, Hu O, Iguchi T, Kuroda Y, Ito S, Eguchi H, Sugimachi K, Saeki H, Oki E, Maehara Y, Suzuki A, Mimori K
    Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer
    ONCOTARGET 8(64):107666-107677, 2017
20. Kondo H, Shimono Y, Mukohyama J, Tanaka Y, Shibuya N, Minami H, Kakeji Y, Suzuki A
    Discordance of MCM7 mRNA and its intronic microRNA levels under hypoxia
    ANTICANCER RESEARCH 37(7), 3885-3890, 2017
21. Sugimachi K, Nishio M, Aishima S, Kuroda Y, Iguchi T, Komatsu H, Hirata H, Sakimura S, Eguchi H, Bekki Y, Takenaka K, Maehara Y, Suzuki A, Mimori K
    Altered expression of Hippo signaling pathway molecules in intrahepatic cholangiocarcinoma
    ONCOLOGY 93(1): 67-74, 2017
22. Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, Sasaki T, Maehama T, Nishina H, Mimori K, Nakano T, Shimizu H, Mak TW , Nakao K, Nakanishi Y, Suzuki A
    MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion, and tumor formation
    ONCOGENE 36(29): 4201-4211, 2017
23. Okada Y, Sonoshita M, Kakizaki F, Aoyama N, Itatani Y, Uegaki M, Sakamoto H, Kobayashi T, Inoue T, Kamba T, Suzuki A, Ogawa O, Taketo M
    Amino-terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer
    CANCER SCIENCE, 108(4), 744-752, 2017 doi: 10.1111/cas.13187
24. Kimura H, Eguchi S, Sasaki J, Kuba K, Nakanishi H, Takasuga S, Yamazaki M, Goto A, Watanabe H, Itoh H, Imai Y, Suzuki A, Mizushima N, Sasaki T
    Vps34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy
    JCI INSIGHT 12;2(1):e89462, 2017
25. Yang YR, Jung JH, Kim SJ, Hamada K, Suzuki A, Kim HJ, Lee JH, Kwon OB, Lee YK, Kim J, Kim EK, Jang HJ, Kang DS, Choi JS, Lee CJ, Marshall J, Koh HY, Kim CJ, Seok H, Kim SH, Choi JH, Choi YB, Cocco L, Ryu SH, Kim JH, Suh PG
    Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior
    MOLECULAR PSYCHIATRY, 22(10), 1473-1482, 2017 doi:10.1038/mp.2016.261.
26. Saito F, Tashiro H, Yamaguchi M, Honda R, Ohba T, Suzuki A, Katabuchi H
    Development of a mouse model for testing therapeutic agents: the anticancer effect of dienogest on endometrial neoplasms
    GYNECOL ENDOCRINOL, 32(5):403-7, 2016
27. Chiba T, Ishihara E, Miyamura N, Narumi R, Kajita M, Fujita Y, Suzuki A, Ogawa Y, Nishina H
    MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status
    SCIENTIFIC REPORT 6:28383, 2016
28. Matsushita Y, Sakai Y, Shimmura M, Shigeto H, Nishio M, Akamine S, Sanefiji M Ishizaki Y, Torisu H, Nakabeppu Y, Suzuki A, Takada H, Hara T
    Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice
    SCIENTIFIC REPORTS 6:22991, 2016
29. Hikasa H, Sekido Y, Suzuki A
    Merlin/NF2-Lin28B-let-7 is a novel tumor-suppressive pathway that is cell density-dependent and Hippo-independent
    CELL REPORTS 14(12):2950-61, 2016
30. Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, Takano Y, Hikasa H, Itoh T, Suzuki SO, Kurihara H, Aishima S, Leask A, Sasaki T, Nakano T, Nishina H, Nishikawa Y, Sekido Y, Nakao K, Shin-ya K, Mimori K, Suzuki A
    Dysregulated YAP1/TAZ and TGF-beta signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE USA 113(1), E71-80, 2016
31. Murata Y, Kotani T, Supriatna Y, Kitamura Y, Imada S, Kawahara K, Nishio M, Daniwijaya EW Sadakata H, Kusakari S, Mori M, Kanazawa Y, Saito Y, Okawa K, Takeda-Morishita M, Okazawa H, Ohnishi H, Azuma T, Suzuki A, Matozaki T
    Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE USA 112(31),E4264-71, 2015
32. Takahashi Y, Sheridan P, Niida A, Sawada G, Uchi R, Mizuno H, Kurashige J, Sugimachi K, Sasaki S, Shimada Y, Hase K, Kusunoki M, Kudo S, Watanabe M, Yamada K, Sugihara K, Yamamoto H, Suzuki A, Doki Y, Miyano S, Mori M, Mimori K
    The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC
    ANNALS OF ONCOLOGY 26(5), 935-42, 2015
33. Nagahama Y, Sone M, Chen X, Okada Y, Yamamoto M, Xin B, Matsuo Y, Komatsu M, Suzuki A, Enomoto K, Nishikawa Y
    Contributions of hepatocytes and bile ductular cells in ductular reactions and remodeling of the biliary system after chronic liver injury
    AMERICAN JOURNAL OF PATHOLOGY 184(11), 3001-12, 2014
34. Yamamoto-Kataoka S, Ebihara K, Aizawa-Abe M, Nishio M, Kusakabe T, Yamamoto Y, Aotani D, Sakai T, Zhao M, Ebihara C, Gumbilai VM, Hosoda K, Suzuki A, Nakao K
    Leptin improves fatty liver independently of insulin sensitization and appetite suppression in hepatocytespecific Pten-deficient mice with insulin hypersensitivity
    HORMONE AND METABOLIC RESEARCH 47(3), 168-75, 2015
35. Hayashi K, Momoi Y, Tanuma N, Kishimoto A, Ogoh H, Kato H, Suzuki M, Sakamoto Y, Inoue Y, Nomura M, Kiyonar H, Sakayori M, Fukamachi K, Kakugawa Y, Yamashita Y, Ito S, Sato I, Suzuki A, Nishio M, Suganuma M, Watanabe T, Shima H
    Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA
    ONOCOGENE 34(35), 4647-55, 2015
36. Pulido R, Baker SJ, Barata JT,Carracedo A, Cid VJ, Chin-Sang ID, Dave V, den Hertog J, Devreotes P,Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, Jiang X, Lee SR, Losche M, Malaney P, Matias-Guiu X, Molina M, Pandolfi PP, Parsons R, Pinton P, Rivas C, Rocha RM, Rodriguez MS, Ross AH, Serrano M, Stambolic V, Stiles B, Suzuki A, Tan SS, Tonks NK, Trotman LC, Wolff N, Woscholski R, Wu H, Leslie NR
    A Unified Nomenclature and Amino Acid Numbering for Human PTEN
    SCIENCESIGNALING 7(332) Pe15, 1-4, 2014
37. Maehama T, Kawahara K, Nishio M, Suzuki A, Hanada K
    Nucleolar Stress Induces Ubiquitination-Independent Proteasomal Degradation of PICT1
    JOURNAL OF BIOLOGICAL CHEMISTRY 289(30), 20802-12, 2014
38. Okamura K, Takayama K, Kawahara K, Harada T, Nishio M, Otsubo K, Ichijo K, Kohno M, Iwama E, Fujii A, Ota K, Koga T, Okamoto T, Suzuki A, Nakanishi Y
    PICT1 expression is a good prognostic factor in non-small cell lung cancer
    ONCOSCIENCE 1 (5), 375-82, 2014
39. Kajimoto H, Kai H, Aoki H, Uchiwa H, Aoki Y, Yasuoka S, Anegawa T, Mishina Y, Suzuki A, Fukumoto Y, Imaizumi T
    BMP type I Receptor Inhibition Attenuates Endothelial Dysfunction in Mice with Chronic Kidney Disease
    KIDNEY INTERNATIONAL 87(1), 128-36, 2014
40. Wang L, Opland D, Tsai S, Luk CT, Schroer SA, Allison MB, Elia AJ, Furlonger C, Suzuki A, Paige CJ, Mak TW, Winer DA, Myers MG Jr, Woo M
    Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex
    NATURE MEDICINE 20(5), 484-92, 2014
41. Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, Yamamoto M
    Nrf2 enhances cholangiocyte expansion in Pten-deficient livers
    MOLECULAR AND CELLULAR BIOLOGY 34(5), 900-13, 2014
42. Sugimachi K, Yokobori T, Iinuma H, Ueda M, Ueo H, Shinden Y, Eguchi H, Sudo T, Suzuki A, Maehara Y, Mori M, Mimori K
    Aberrant Expression of Plastin-3 Via Copy Number Gain Induces the Epithelial-Mesenchymal Transition in Circulating Colorectal Cancer Cells.
    ANNALS OF SURGICAL ONCOLOGY in press
43. Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Noguchi C, Katagi A, Nishio M, Suzuki A, Tokuda M.
    The expression of PTEN in the development of mouse cochlear lateral wall.
    NEURO SCIENCE 258(1), 263-9, 2014
44. Uchi R, Kogo R, Kawahara K, Sudo T, Yokobori T, Eguchi H, Sugimachi K, Maehama T, Mori M, Suzuki A, Komune S, Mimori K.
    PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression.
    BRITISH JOURNAL OF CANCER 109(8), 2199-206, 2013
45. Liao J, Marumoto T, Yamaguchi S, Okano S, Takeda N, Sakamoto C, Kawano H, Nii T, Miyamato S, Nagai Y, Okada M, Inoue H, Kawahara K, Suzuki A, Miura Y, Tani K
    Inhibition of PTEN Tumor Suppressor Promotes the Generation of Induced Pluripotent Stem Cells.
    MOLECULAR THERAPY in press, 2013
46. Ishibashi M, Kogo R, Shibata K, Ueo H, Uchi R, Matsumura T, Takano Y, Sawada G, Takahashi Y, Mima K, Kurashige J, Akiyoshi S, Iwaya T, Eguchi H, Sudo T, Sugimachi K, Suzuki A, Wakabayashi G, Mori M, Mimori K
    Clinical Significance of PICT1 in Patients of Hepatocellular Carcinoma with Wild-Type TP53.
    ANNALS OF SURGICAL ONCOLOGY in press, 2013
47. Takasuga S, Horie Y, Sasaki J, Sun-Wada GH, Kawamura N, Iizuka R, Mizuno K, Eguchi S, Kofuji S, Kimura H, Yamazaki M, Horie C, Odanaga E, Sato Y, Sato Y, Chida S, Kotani K, Harada A, Katada T, Suzuki A, Wada Y, Ohnishi H, Sasaki T.
    Critical roles of type Ⅲ phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE USA 110(5); 1726-31,2013.
48. Panasyuk G, Espeillac C, Chauvin C, Pradelli LA, Horie Y, Suzuki A, Annicotte JS, Faias L, Foretz M, Verdeguer F, Pontoglio M, Ferre P, Scoazec JY, Bimbaum MJ, Ricci JE, Pende M
    PPARg contributes to PKM2 and HK2 expression in fatty liver
    NATURE COMMUNICATIONS in press, 2012
49. Kogo R, shimamura T, Mimori K, Kawahara K, Imoto S, Sudo T, Tanaka F, Shibata K, Suzuki A, Komune S, Miyano S, Mori M
    Long noncoding RNA HOTAIR regulates polycomb-dependent chromartin modification and is associated with poor prognosis in colorectal cancers.
    CANCER RESEARCH 71(20): 6320-6326, 2011
50. Saito F, Tashiro H, To Y, Ohtake H, Ohba T, Suzuki A, Katabuchi H Mutual contribution of Pten and estrogen to endometrial carcinogenesis in a PtenloxP/loxP mouse model
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 21(8): 1343-1349, 2011
51. Masato Sasaki, Kohichi Kawahara (equal contribution), Miki Nishio, Koshi Mimori, Ryunosuke Kogo, Koichi Hamada, Bunsho Itoh, Jia Wang, Yukako Komatsu, Yong Ryoul Yang, Hiroki Hikasa, Yasuo Horie, Takayuki Yamashita, Takehiko Kamijo, Yanping Zhang, Yan Zhu, Carol Proves, Toru Nakano, Tak Wah Mak, Takehiko Sasaki, Tomohiko Marehama, Masaki Mori, Akira Suzuki
    Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11
    NATURE MEDICINE in press, 2011
    （私達のものがこの号のTopicとして News and Viewsに選ばれました）
52. Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N.
    Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathway.
    DEVELOPMENT 138(8): 1507-1519, 2011
53. Patzak IM, Konigsberger S, Suzuki A, Mak TW, Kiefer F.
    HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.
    EUROPEAN LOURNAL OF IMMUNOLOGY 40(11): 3220-3225, 2010
54. Wang L, Liu Y, Yan Lu S, Nguyen KT, Schroer SA, Suzuki A, Mak TW, Gaisano H, Woo M
    Deletion of Pten in pancreatic beta-cells protects against deficient beta cell mass and function in mouse models of type 2 diabetes
    DIABETES 59(12): 3117-3126, 2010
55. Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Suzuki A, Holley M, Tokuda M
    Role of PTEN in the development of the mammalian auditory system
    NEUROREPORT 21(10): 731-735, 2010
56. Sasaki J, Kofuji S, Itoh R, Momiyama T, Takayama K, Murakami H, Chida S, Tsuya Y, Takasuga S, Eguchi S, Asanuma K, Horie Y, Miura K, Davis M, Mitchell C, Yamazaki M, Hirai H, Takenawa T, Suzuki A, Sasaki T
    The PtdIns(3,4)P2-phosphatase INPP4A is a suppressor of excitotoxic neuronal death.
    NATURE 465(7297):497-501, 2010
57. Asano J, Tada H, Onai N, Sato T, Horie Y, Fujimoto Y, Fukase K, Suzuki A, Mak TW, Ohteki T
    Nod-like receptor signaling enhances dendritic cell-mediated cross-priming in vivo.
    JOURNAL OF IMMUNOLOGY 184(2): 736-745, 2010
58. Alzabin S, Pyarajan S, Yee H, Kiefer F, Suzuki A, Burakoff S, Sawasdikosol S
    Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response
    CANCER IMMUNOLOGY, IMMUNOTHERAPY 59(3): 419-429, 2010
59. Anezaki Y, Ohshima S, Ishii H, Kinoshita N, Dohmen T, Kataoka E, Sato W, Iizuka M, Goto T, Sasaki J, Sasaki T, Suzuki A, Ohnishi H, Horie Y
    Sex difference in the liver of hepatocyte-specific Pten-deficient mice: A model of nonalcoholic steatohepatitis
    HEPATOLOGY RESEARCH 39(6): 609-618, 2009
60. Tsuda M, Inoue-Narita T, Suzuki A, Itami S, Blumenberg M, Manabe M
    Induction of gene encoding FABP4 in Pten-null keratinocytes.
    FEBS LETTERS 583(8), 1319-1322, 2009
61. Ishii H, Horie Y, Ohshima S, Anezaki Y, Kinoshita N, Dohmen T, Kataoka E, Sato W, Goto T, Sasaki J, Sasaki T, Watanabe S, Suzuki A, Ohnishi H.
    Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice.
    JOURNAL OF HEPATOLOGY 50(3): 562-571, 2009.
62. Radziszewska A, Choi D, Nguyen KT, Schroer SA, Tajmir P, Wang L, Suzuki A, Mak TW, Evan GI, Woo M
    PTEN deletion and concomitant c-Myc activation does not lead to tumor formation in pancreatic beta cells.
    JOURNAL OF BIOLOGICAL CHEMISTRY 284(5): 2917-2922, 2009 .
63. Inoue-Narita T, Hamada K, Sasaki T, Hatakeyama S, Fujita S, Kawahara K, Sasaki M, Kishimoto H, Eguchi S, Kojima I, Beermann F, Kimura T, Osawa M, Itami S, Mak TW, Nakano T, Manabe M, Suzuki A
    Pten deficiency in melanocytes results in resistance to hair graying and susceptiblity to carcinogen-induced melanomagenesis
    CANCER RESAERCH 68(14): 5760-8, 2008
64. Choi D, Nguyen KT, Wang L, Schroer S, Suzuki A, Mak TW, Moo M
    Partial deletion of PTEN in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone
    ENDOCRINOLOGY 149(9): 4382-6, 2008
65. Kuroda S, Nishio M, Sasaki T, Horie Y, Kawahara K, Sasaki M, Natsui M, Matozaki T, Tezuka H, Ohteki T, Forster I, Mak TW, Nakano T, Suzuki A
    Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages
    EUROPEAN JOURNAL OF IMMUNOLOGY 38(5): 1331-40, 2008
66. Xue L, Nolla H, Suzuki A, Mak TW, Winoto A
    Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
    PROCEEDING OF NATIONAL ACADEMY OF SCIENCE USA 105(6) 2022-2027, 2008
67. Qui W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Iqbai J, Kontos CD, Horie Y, Suzuki A, Adeli K
    Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.
    HEPATOLOGY 48(6): 1799-1809, 2008
68. Plum L, Rother E, Munzberg H, Wunderlich FT, Morgan DA, Hampel B, Shanabrough M, Janoschek R, Konner AC, Alber J, Suzuki A, Krone W, Horvath TL, Rahmouni K, Bruning JC.
    Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation.
    CELL METABOLISM 6(6):431-445, 2007
69. Yanagi S, Kishimoto H, Kawahara K, Sasaki T, Sasaki M, Nishio M, Yajima N, Hamada K, Horie Y, Kubo H, Mak TW, Nakano T, Nakazato M, Suzuki A
    Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas
    JOURNAL OF CLINICAL INVESTIGATION,　117(10) 2929-40, 2007
    (この号のhighlightに選ばれました）
70. Sasaki M, Ohnishi M, Tashiro F, Niwae H, Suzuki A, Miyazaki J, Kobayashi T, Tamura S.
    Disruption of the mouse protein Ser/Thr phosphatase 2Cβ gene leads to early pre-implantation lethality.
    MECHANISMS OF DEVELOPMENT 124(6), 489-99, 2007
71. Kishimoto H, Ohteki T, Yajima N, Kawahara K, Natsui M, Kawarasaki S,Hamada K, Horie Y, Kubo Y, Arase S, Taniguchi M, Vanhaesebroeck B, Mak TW, Nakano N, Koyasu S, Sasaki T, and Suzuki A
    The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells
    BLOOD 109(8),3316-24 , 2007
72. Nishio M, Watanabe K, Sasaki J, Taya C, Takasuga S, Iizuka R, Bella T,Yamazaki M, Watanabe H, Kuroda S, Itoh R, Förster I, Mak TW, Kanaho Y,Yonehara H, Penninger JM, Suzuki A(equal last author), Sasaki T.
    Control of Cell Polarity and motility by PI(3,4,5)P3 phosphatase SHIP
    NATURE CELL BIOLOGY 9(1),36-44, 2007
73. Tsuruta H, Kishimoto H, Sasaki T, Horie Y, Natsui M, Shibata Y, Hamada K, Yajima N, Kawahara K, Sasaki M, Tsuchiya N, Enomoto K, Mak TW, Nakano T, Habuchi T, Suzuki A
    Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients.
    CANCER RESEARCH, 66(17), 8389-96, 2006.
    (この号のhighlightに選ばれました）
74. Zhao M, Song B, Pu J, Wada T, Reid B, Tai G, Wang F, Guo A, Walczysko P, Gu Y, Sasaki T, Suzuki A, Forrester JV, Bourne HR, Devreotes PN, McCaig CD, Penninger JM
    Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN
    NATURE 442(7101), 457-60, 2006
75. Plum L, Ma X, Hampel B, Balthasar N, Coppari R, M ü nzberg H,Shanabrough M, Burdakov D, Rother E, Janoschek R,Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A,Mak TW, Krone W, Horvath TL,
    Ashcroft FM, Br ü ning JC
    Enhanced PIP3 Signaling in POMC Neurons Causes Neuronal Silencing via KATP Channel Activation and Leads to Diet-sensitive Obesity.
    JOURNAL OF CLINICAL INVESTIGATION 116(7), 1886-901, 2006
76. Nguyen KT, Tajmir P, Lin CH, Liadis N, Zhu XD, Eweida M, Tolasa-Karaman G, Cai F, Wang R, Kitamura T, Belsham DD, Wheeler MB, Suzuki A, Mak TW, Woo M
    Essential role of Pten in body size determination and pancreatic beta cell homeostasis in vivo
    MOLECULAR AND CELLULAR BIOLOGY, 26(12), 4511-8, 2006
77. Sato W, Horie Y, Kataoka E, Ohshima S, Dohmen T, Iizuka M, Sasaki J, Sasaki T, Hamada K, Kishimoto H, Suzuki A, Watanabe S
    Hepatocic gene expression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge.
    HEPATOLOGY RESEARCH 34(4), 256-65, 2006
78. Begum M, Tashiro H, Katabuchi H, Suzuki A, Kurman RJ, Okamura H
    Neonatal estrogen exposure suppress PTEN-related endometrial carcinogenesis in recombinant mice.
    LABORATORY INVESTIGATION 86(3), 286-296, 2006
79. Hamada K, Sasaki T, Koni PA, Natsui M, Kishimoto H, Sasaki J, Yajima N, Hasegawa G, Miyazaki J, Suda T, Itoh H, Nakao K, Mak TW, Nakano T, Suzuki A
    The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis.
    GENES AND DEVELOPMENT19(17), 2054-2065, 2005
    （私達のものがこの号のAdvance Online Articleに選ばれました）
80. Sasaki J,Sasaki T,Yamazaki M,Matsuoka K,Taya C,Shitara H,Takasuga S,Nishio M,Mizuno K,Wada T,Miyazaki H,Watanabe H,Iizuka R,Kubo S,Murata S,Chiba T,Maehama T,Hamada K,Kishimoto H,Frohman MA,Tanaka K,Penninger JM,Yonekawa H,Suzuki A,Kanaho Y
    Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I alpha.
    JOURNAL OF EXPERIMENTAL MEDICINE 201(6),859-870, 2005
81. Wijesekara N, Konrad D, Edeida M, Jefferies C, Liadis N, Giacca A, Crockower M, Suzuki A, Mak TW, Kahn CR, Klip A, Woo M
    Muscle-specific Pten deletion protects against insulin resistance and diabetes.
    MOLECULAR AND CELLULAR BIOLOGY 25(3), 1135-1145, 2005
82. Horie Y, Suzuki A (equal first and corresponding author), Kataoka Ei, Sasaki T, Hamada K, Junko Sasaki, MIzuno K, Hasegawa G, Kishimoto H, Iizuka M, Naito M, Enomoto K, Watanabe S, Mak TW, Nakano T
    Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
    JOURNAL OF CLINICAL INVESTIGATION 113(12), 1774-1783, 2004
    ( 私達のものが表紙を飾りました）

    

    

83. Backman SA, Ghazarian D, So K, Sanchez O, Wagner KU, Hennighausen L, Suzuki A, Tsao MS, Chapman WB, Stambolic V, Mak TW.
    Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten.
    PROC NATL ACAD SCI USA. 101(6), 1725-30, 2004
84. Nishita M, Yan W, Goto K,Tomizawa C, Suzuki A, Niwa R, Umekura T, Mizuno K
    PI3-kinase-Mediated Activation of Cofilin Phosphatase Slingshot-1L Controls Insulin-induced Membrane Protrusion
    JOURNAL OF BIOLOGICAL CHEMISTRY 279(8), 7193-7198, 2004
85. Kishimoto H, Nakagawa K, Watanabe T, Kitagawa D, Momose H, Seo J, Nishitai G, Shimizu N, Ohata S, Tanemura S, Asaka S, Goto T, Fukushi H, Yoshida H, Suzuki A, Sasaki T, Wada T, Penninger JM, Nishina H, Katada T
    Different Properties of SEK1 and MKK7 in Dual Phosphorylation of Stressinduced Activated Protein Kinase SAPK/JNK in Embryonic Stem Cells
    JOURNAL OF BIOLOGICAL CHEMISTRY 278(19), 16595-16601, 2003
86. Suzuki A, Itami S, Ohishi M, Yamaguchi MT, Hamada K, Inoue T, Komazawa N, Senoo H, Sasaki T, Takeda J, Manabe M, Mak TW, Nakano T
    Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
    CANCER RESEARCH 63(3), 674-681, 2003
    ( 私達のものが表紙を飾りました）

    

87. Suzuki A, Kaisho T, Ohishi M, Yamaguchi MT, Tsubata T, Koni PA, Sasaki T, Mak TW, Nakano T
    Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination
    JOURNAL of EXPERIMANTAL MEDICINE 197(5), 657-667, 2003
88. Kimura T, Suzuki A, Fujita Y, Yomogida Y, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T
    Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
    DEVELOPMENT 130(8), 1691-1700, 2003
89. Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sasaki T, Suzuki A, Sasaki JI, Sah R, Cheng HYM, Oliveira-dos-Santos AO, Benovic JL, Kahn CR,
    Izumo S, Steinberg SF, Backx PH, Penninger J
    Regulation of heart muscle contractility by the PI3Kg-PTEN signaling pathway
    CELL 110(6) 737-749, 2002
90. Tanigaki K, Han H, Yamamoto N, Tashiro K, Ikegawa M, Kuroda K, Suzuki A, Nakano T and Honjo T
    Notch / RBP-J signaling is involved in cell fate determination of Marginal Zone B cells
    NATURE IMMUNOLOGY 3(5), 443-50, 2002
91. Cheung AM, Hande MP, Jalali F, Tsao MS, Skinnider B, Hirao A, McPherson JP, Karaskova J, Suzuki A, Wakeham A, You-Ten A, Elia A, Squire J,Bristow R, Hakem R, Mak TW.
    Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.
    CANCER RESEARCH 62(21), 6194-204, 2002
92. Itoh H, Komatsuda A, Ohtani H, Wakui H, Imai H, Sawada K, Otaka M, Ogura M, Suzuki A, Hamada F
    Mammalian HSP60 is quickly sorted into the mitchondria under dehydration
    EUROPEAN JOURNAL of BIOCHEMISTRY 269(23), 5931-5938, 2002
93. Matsumori M, Itoh H, Toyoshima I, Komatsuda A, Sawada K, Fukuda J, Tanaka T, Okubo A, Kinouchi H, Mizoi K., Hama T, Suzuki A, Hamada F, Shoji Y, Takada G
    Characterization of the 105-kDa molecular chaperone: Identification, biochemical properties, and lozalization
    EUROPEAN JOURNAL of BIOCHEMISTRY 269(22), 5632-5641, 2002
94. Higuchi, M., Masuyama, N., Fukui, Y., Suzuki, A. and Gotoh, Y.
    Akt mediates Rac/Cdc42-Regulated Cell Motility in Growth Factor-Stimulated Cells and in Invasive PTEN-Knockout Cells.
    CURRENT BIOLOGY 11(24), 1958-1962, 2001.
95. Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, Tsao MS, Shannon P, Bolon B, Ivy GO, Mak TW.
    Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.
    NATURE GENETICS 29(4), 396-403, 2001.
96. Sasaki T, Wada T, Kishimoto H, Irie-Sasaki J, Matsumoto G, Goto T, Yao Z, Wakeham A, Mak TW, Suzuki A, Cho SK, Zuniga-Pflucker JC,
    Oliveira-dos-Santos AJ, Katada T, Nishina H, Penninger JM.
    The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in
    hematopoietic cells.
    JOURNAL of EXPERIMANTAL MEDICINE194(6), 757-768, 2001.
97. Suzuki A, Yamaguchi MT, Ohteki T, Sasaki T, Kaisho T, KimuraY, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi P, Koyasu S, Penninger JM, Nakano T and Mak TW
    T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance
    IMMUNITY 14, 523-534, 2001
98. Sasaki T, Sasaki JI, Horie Y,Bachmaier K, Fata JE, Li M, Suzuki A, Bouchard D, Ho A, Redston M, Gallinger S , Khokha R, Mak TW, Hawkins PT, Stephens L, Scherer SW, Tsao M, Penninger JM
    Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)K-gammma
    NATURE 406, 897-902, 2000
99. Stambolic V, Tsao MS, Macpherson D, Suzuki A, Chapman WB, Mak TW
    High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice.
    CANCER RESEARCH 60(13), 3605-11, 2000
100. Sasaki T, Sasaki JI, Jones RG, Oliveira-dos-Santos AJ, Stanford WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi
     PS, Suzuki A, Penninger JM
     Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration.
     SCIENCE 287(5455), 1040-1046, 2000
101. Suzuki-A, de la Pompa-JL, Stambolic-V, Elia-AJ, Sasaki-T, Barrantes-IB, Ho-A, Wakeham-A, ltie-A, Khoo-W, Fukumoto-M, Mak-TW
     High cancer susceptibility and embryonic lethality associated with mutation of
     the PTEN tumor suppressor gene in mice.
     CURRENT BIOLOGY 8(21),1169-78,1998
102. Stambolic-V, Suzuki-A(equal first contributor), de la-Pompa JL, Brothers-GM, Mirtsos-C, Sasaki-T, Ruland-J, Penninger-JM, Siderovski-DP, Mak-TW
     Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.
     CELL 95(1),29-39 ,1998
103. Suzuki-A. de-la-Pompa-JL. Hakem-R. Elia-A. Yoshida-R. Mo-R. Nishina-H. Chuang-T. Wakeham-A. Itie-A. Koo-W. Billia-P. Ho-A. Fukumoto-M.
     Hui-CC. Mak-TW.
     Brca2 is required for embryonic cellular proliferation in the mouse.
     GENES AND DEVELOPMENT 11(10), 1242-52, 1997.
     ( 私達のものが表紙を飾りました）
104. Suzuki-A. Andrew-DP. Gonzalo-JA. Fukumoto-M. Spellberg-J. Hashiyama-M. Takimoto-H. Gerwin-N. Webb-I. Molineux-G. Amakawa-R. Tada-Y. Wakeham-A. Brown-J. McNiece-I. Ley-K. Butcher-EC. Suda-T. Gutierrez-Ramos-JC. Mak-TW.
     CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein.
     BLOOD 87(9), 3550-62, 1996.
105. Grossman-A. Mittruecker-HW. Nicholl-J. Suzuki-A. Chung-S. Antonio-L. Suggs-S. Sutherland-GR. Siderovski-DP. Mak-TW.
     Cloning of human lymphocyte-specific interferon regulatory factor(hLSIRF/hIRF4) and mapping of the gene to 6p23-p25.
     GENOMICS 37(2), 229-33, 1996.
106. Tsuyuoka-R. Takahashi-T. Suzuki-A. Sasaki-Y. Nakamura-K. Fukumoto-M. Ohmori-K. Ohno-Y. Nakao-K.
     A newly established megakaryoblastic/erythroid cell line that differentiates to red cells in the presence of erythropoietin and produces platelet-like particles.
     STEM CELLS 13(1), 54-64, 1995.
107. TAKAHASHI T, Suzuki A.
     LIVER-DAMAGE IN PATIENTS WITH CSF-PRODUCING TUMORS - REPLY
     AMERICAN JOURNAL OF MEDICINE
     98 (6): 601-602 JUN 1995
108. Suzuki-A. Takahashi-T. Okuno-Y. Tsuyuoka-R. Sasaki-Y. Fukumoto-M. Katakami-H. Kita-K. Shibuya-T.
     Production of parathyroid hormone-related protein by cultured human myeloma cells.
     AMERICAN JOURNAL OF HEMATOLOGY. 45(1), 88-90, 1994.
109. Tsuyuoka-R. Takahashi-T. Sasaki-Y. Taniguchi-Y. Fukumoto-M. Suzuki-A. Nakamura-K. Kobayashi-S. Kudo-T. Nakao-K.
     Colony-stimulating factor-producing tumours: production of granulocyte colony-stimulating factor and interleukin-6 is secondary to interleukin-1 production.
     EUROPEAN JOURNAL OF CANCER 30A(14), 2130-6, 1994.
110. Suzuki-A. Takahashi-T. Okuno-Y. Seko-S. Fukuda-Y. Nakamura-K. Fukumoto-M. Konaka-Y. Imura-H.
     Liver damage in patients with colony-stimulating factor-producing tumors.
     AMERICAN JOURNAL OF MEDICINE 94(2), 125-32, 1993.
111. Fukumoto-M. Suzuki-A. Inazawa-J. Yoshimura-T. Arao-S. Takahashi-T. Nomura-H. Hiai-H.
     Chromosomal location and structure of amplicons in two human cell lines with coamplification of c-myc and Ki-ras oncogenes.
     SOMATIC CELL AND MOLECULAR GENETICS 19(1), 21-8, 1993.
112. Suzuki-A. Takahashi-T. Nakamura-K. Tsuyuoka-R. Okuno-Y. Enomoto-T. Fukumoto-M. Imura-H.
     Thrombocytosis in patients with tumors producing colony-stimulating factor.
     BLOOD 80(8), 2052-9, 1992.
113. Suzuki-A. Takahashi-T. Okuno-Y. Tsuyuoka-R. Fukumoto-M. Nakamura-K. Imura-H.
     IL-1 production as a regulator of G-CSF and IL-6 production in CSF-producing cell lines.
     BRITISH JOURNAL OF CANCER 65(4), 515-8, 1992.
114. Takahashi-T. Nakamura-K. Nishikawa-S. Tsuyuoka-R. Suzuki-A. Murakami-M. Amenomori-M. Okuno-Y. Imura-H.
     Interleukin-5 in eosinophilic gastroenteritis.
     AMERICAN JOURNAL OF HEMATOLOGY 40(4), 295-8, 1992.
115. Okuno-Y. Takahashi-T. Suzuki-A. Fukumoto-M. Nakamura-K. Fukui-H. Koishihara-Y. Ohsugi-Y. Imura-H.
     Acquisition of growth autonomy and tumorigenicity by an interleukin 6-dependent human myeloma cell line transfected with interleukin 6 cDNA.
     EXPERIMENTAL HEMATOLOGY 20(4), 395-400, 1992.
116. Suzuki-A. Takahashi-T. Okuno-Y. Nakamura-K. Tashiro-H. Fukumoto-M. Konaka-Y. Imura-H.
     Analysis of abnormal expression of g-csf gene in a novel tumor cell line (KHC 287) elaborating G-CSF, IL-1 and IL-6 with co-amplification of c-myc and
     c-ki-ras.
     INTERNATIONAL JOURNAL OF CANCER 48(3), 428-33, 1991.
117. Suzuki-A. Takahashi-T. Taniguchi-A. Kotake-C. Seo-T. Toda-T. Kobayashi-K. Tsukamoto-N. Fukumoto-M.
     Pure red cell aplasia associated with non-Hodgkin's lymphoma and hemolytic anemia.
     JAPANESE JOURNAL OF CLINICAL ONCOLOGY 21(5), 384-7, 1991.
118. Suzuki-A. Takahashi-T. Okuno-Y. Fukumoto-M. Fukui-H. Koishihara-Y. Ohsugi-Y. Ohno-Y. Imura-H.
     Estimation of interleukin 6 production by reverse transcriptase-polymerase chain reaction in four human myeloma cell lines.
     LEUKEMIA RESEARCH 15(11), 1043-50, 1991.
119. Nakamura-K. Takahashi-T. Tsuyuoka-R. Ueda-Y. Suzuki-A. Okuno-Y. Ihara-Y. Seko-S. Okada-T. Kumagai-N. Oyaizu-T, Nishimura-T
     Identification of colony-stimulating factor activity in patients with malignant tumors associated with excessive leukocytosis.
     JAPANESE JOURNAL OF CLINICAL ONCOLOGY 21(6), 395-9, 1991.
120. Takahashi-T. Suzuki-A. Ichiba-S. Okuno-Y. Sugiyama-H. Imura-H. Nakamura-K. Iho-S. Hoshino-T.
     Effect of 1,25(OH)2D3 on normal human CFU-GM: target cells of the agent in the suppression of colony formation and induction of macrophage colonies.
     INTERNATIONAL JOURNAL OF HEMATOLOGY 54(1), 57-63, 1991.
121. Okuno-Y. Takahashi-T. Suzuki-A. Ichiba-S. Nakamura-K. Okada-T. Okada-H. Imura-H. In vitro growth pattern of myeloma cells in liquid suspension or semi-solid culture containing interleukin-6.
     INTERNATIONAL JOURNAL OF HEMATOLOGY 54(1), 41-7, 1991.
122. Takahashi-T. Tsuyuoka-R. Ueda-Y. Suzuki-A. Ichiba-S. Okuno-Y. Nakamura-K. Imura-H. Megakaryocyte potentiating activity of IL-1, IL-6 and GM-CSF as evaluated by their action on in vitro human megakaryocytic colonies.
     BRITISH JOURNAL OF HAEMATOLOGY 78(4), 480-7, 1991.
123. Okuno-Y. Takahashi-T. Suzuki-A. Fukumoto-M. Nakamura-K. Imura-H. Co-production of interleukin-1 and interleukin-6 in tumor cell lines elaborating colony-stimulating factors.
     JAPANESE JOURNAL OF CANCER RESEARCH 82(8), 890-2, 1991.
124. Okuno-Y. Takahashi-T. Suzuki-A. Ichiba-S. Nakamura-K. Fukumoto-M. Okada-T. Okada-H. Imura-H.
     Establishment and characterization of four myeloma cell lines which are responsive to interleukin-6 for their growth.
     LEUKEMIA 5(7), 585-91, 1991.
125. Okuno-Y. Suzuki-A. Ichiba-S. Takahashi-T. Nakamura-K. Hitomi-K. Sasaki-R. Tada-K. Imura-H.
     Establishment of an erythroid cell line (JK-1) that spontaneously differentiates to red cells.
     CANCER 66(7), 1544-51, 1990.
126. Okuno-Y. Takahashi-T. Suzuki-A. Ichiba-S. Nakamura-K. Hitomi-K. Sasaki-R. Imura-H.
     Expression of the erythropoietin receptor on a human myeloma cell line.
     BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 170(3), 1128-34, 1990.

総　　説

1. 前濱朝彦、西尾美希、鈴木聡
   核小体ストレスによる細胞死と病態
   医学のあゆみ　2022
2. Maehama T, Nishio M, Otani J, Mak TW, Suzuki A
   The Role of Hippo‐YAP Signaling in Squamous Cell Carcinomas
   Cancer Science 112(1):51-60,2021 doi: 10.1111/cas.14725
3. 前濱 朝彦、西尾 美希、鈴木　聡
   哺乳類Hippo経路による細胞接着の制御と細胞競合
   医学のあゆみ　274(5) 457-462, 2020
4. Shimono Y, Mukohyama J, Isobe T, Johnston DM, Dalerba P, Suzuki A
   Organoid Culture of Human Cancer Stem Cells
   Methods Mol Biol 1576, 23-31, 2019
5. Mukohyama J, Shimono Y, Minami H, Kakeji Y, Suzuki A
   Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells
   CANCERS (Basel) 9(10), pii: E143, 2017
6. Nishio M, Maehama T, Goto H, Nakatani K, Kato W, Omori H, Miyachi Y, Togashi H, Shimono Y, Suzuki A
   Hippo vs. Crab: Tissue-specific functions of the mammalian Hippo pathway
   　 GENES TO CELLS, 22(1):6-31, 2017
7. Nakatani K, Maehama T, Nishio M, Goto H, Kato W, Omori H, Miyachi Y, Togashi H, Shimono Y, Suzuki A
   Targeting the Hippo Signaling Pathway for Cancer Treatment 　
   JOURNAL OF BIOCHEMISTRY, pii: mvw074, 2016
　
8. 後藤裕樹、西尾美希、加藤稚子、前濱朝彦、鈴木聡
   機械的刺激によるHippo-YAZ/TAZ経路の活性化、生理作用、腫瘍進展メカニズムと意義
   （特集：細胞の社会学ー細胞間で繰り広げられる協調と競争）
   生体の科学　67(2), 127-131, 2016
9. 西尾美希、鈴木聡
   YAP1/TAZおよびTGFβ経路を介したMOB1A/1B欠損による肝がん発症機構
   肝細胞研究会, ホットトピックス, 2016
   （http://hepato.umin.jp/hottopics/hottopics014.html）
10. 西尾美希、鈴木聡
    Hippo経路による生体制御機構
    耳鼻咽喉科ニューロサイエンス　29, 1-5, 2015
11. 前濱朝彦, 鈴木聡
    PTEN:脂質ホスファターゼとしての機能と発がんへの関与
    実験医学 33(15), 157-163, 2015
12. 前濱朝彦、鈴木聡
    家族性腫瘍学ー家族性腫瘍の最新研究動向ー
    日本臨床　73 (6) 285-290
13. 前濱朝彦、鈴木聡
    がんと脂質－PTEN/PI3Kシグナルと発がん
    THE LIPID 25(4). 63-69, 2014
14. 後藤裕樹、西尾美希、杉町圭史、三森功士、鈴木 聡
    Hippo経路と腫瘍－Hippo経路変異によるがんモデルマウス－
    医学のあゆみ 251(5), 428-435, 2014
15. Nishio M, Goto H, Suzuki M, Fujimoto A, Mimori K, Suzuki A
    The Hippo Signaling Pathway: A Candidate New Drug Target for Malignant Tumors
    INNOVATIVE MEDICINE : Basic Research and Development (editted by Nakao K), Springer, 79-94, 2015
16. Nishio M, Otsubo K, Maehama T, Mimori K, Suzuki A
    Capturing the Mammalian Hippo: Elucidating Its Role in Cancer
    CANCER SCIENCE 104(10), 1271-1277, 2013
17. 西尾美希、河原康一、佐々木雅人、前濱朝彦、佐々木雄彦、三森功士、森　正樹、鈴木　聡
    核小体を起点としp53を制御する新規分子PICT1による細胞増殖制御機構
    実験医学増刊号　31 (2) 127-134, 2013
18. 西尾美希、三森功士、森　正樹、板見　智、鈴木　聡
    Hippo経路分子MOB1によるがん発症・進展制御とがん治療戦略
    次世代がん戦略研究update　がん基盤生物学 －革新的シーズ育成に向けて－
    南山堂 p200-5, 2013
19. Suzuki A, Kogo R, Kawahara K, Sasaki M, Nishio M, Maehama T, Sasaki T, Mimori K, Mori M
    A new PICTure of the nucleolar stress
    CANCER SCIENCE 103(4), 632-637, 2012
20. 古後龍之介、三森功士、小宗静男、鈴木聡、森　正樹
    核小体ストレス経路を介したp53制御遺伝子PICT1遺伝子の機能～特に大腸癌について～
    大腸癌 Frontier 5(2), 175(82)-179(89) , 2012
21. 西尾美希、佐々木雄彦、鈴木聡
    PTEN変異による発がんモデル
    疾患モデルの作製と利用 ー がん（エル・アイ・シー社）－145-171, 2012
22. 河原康一、西尾美希、佐々木雅人、前濱朝彦、佐々木雄彦、古後龍之介、三森功士、森　正樹、鈴木　聡
    PICT1による核小体ストレス経路を介したp53と腫瘍進展制御～腫瘍予後マーカーや今後の創薬応用にむけて～
    遺伝子Mook22号　最新疾患モデルと創薬応用研究の最前線 260-265,2012
23. Suzuki A, Kogo R, Kawahara K, Sasaki M, Nishio M, Maehama T, Sasaki T, Mimori K, Mori M
    A new PICTure of the nucleolar stress
    CANCER SCIENCE 103(4),632-637,2012
24. Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
    Mammalian phosphoinositide kinases and phosphatases
    PROGRESS IN LIPID RESEARCH, 48(6): 478-487, 2009
25. 矢島伸之、鈴木 聡
    造血幹細胞を制御する遺伝子-PTEN遺伝子
    造血器腫瘍アトラス　改訂第4版　54-59, 2009
26. Knobbe CB, Lapin V, Suzuki A, Mak TW
    The role of PTEN in development, physiology and tumorigenesis in mouse models : a tissue-by-tissue survey
    ONCOGENE 27(41): 5398-415, 2008
27. 河原康一、佐々木雄彦、西尾美希、鈴木聡
    癌抑制遺伝子PTEN異常による各種疾患～PTEN欠損マウスが教えてくれたもの～
    生化学 80(11): 1017-1025, 2008
28. Suzuki A, Nakano T, Mak TW, Sasaki T
    Portrait of PTEN:Messages from Mutant Mice
    CANCER SCIENCE, 9(2)209-13, 2008
29. 鈴木聡
    分子細胞生物学辞典（第二版）’PTEN’
    東京化学同人 731, 2008
30. 濱田浩一、佐々木雄彦、鈴木聡
    血管内皮細胞におけるPTEN/PI3キナーゼシグナル経路の役割
    細胞工学　27 (5): 480-485, 2008
31. Sasaki T, Sasaki J, Watanabe K, Suzuki A.
    Non-invasive visualization of the lipid product of class I PI3K in transgenic mouse models.
    BIOCHEMICAL SOCIETY TRANSACTION 35(Pt 2),215-8, 2007
32. Suzuki A, Hamada K, Sasaki T, Mak TW, Nakano T
    Role of Pten/PI3K pathway in endothelial cells
    Biochemical Society Transaction 35(Pt 2),172-6,2007
33. 佐々木雅人、佐々木雄彦、鈴木 聡
    血液細胞におけるPTENの役割
    血液・腫瘍科 54(2),237-243,2007
34. 河原康一、濱田浩一、佐々木雄彦、鈴木聡
    PTEN/PI3K経路による血管制御
    医学のあゆみ 223(13), 1015-1022, 2007
35. 西尾美希、鈴木聡、佐々木雄彦
    PtdIns(3,4,5)P3代謝酵素による好中球遊走の制御経路の役割
    細胞工学26(5), 552-553, 2007
36. 佐々木雄彦、渡辺健一、鈴木聡
    脂質結合モジュールによるイノシトールリン脂質動態解析
    実験医学増刊号「形と運動を司る細胞のダイナミクス」
    24(13), 180(2018)-185(2023), 2006
37. 濱田浩一、佐々木雄彦、鈴木聡
    血管形成・腫瘍血管新生におけるPTEN/PI3K経路の役割
    実験医学増刊号　急速進展する血管研究　24(18), 67(2767)-74(2774), 2006
38. 柳重久、中里雅光、鈴木聡
    がん抑制遺伝子ＰＴＥＮ
    遺伝子医学MOOK 6 169-175, 2006
39. 堀江泰夫、片岡英、大嶋重敏、佐藤亘、道免孝洋、渡邊純夫、鈴木聡
    生活習慣と肝臓病:診断と治療の進歩～非アルコール性脂肪性肝炎～NASHの病態解明（実験モデルからのレッスン）
    日本内科学雑誌95(1), 57-65, 2006
40. 佐々木雄彦、高須賀俊輔、佐々木純子、鈴木聡
    幹細胞のシグナル伝達～PI3／Akt～
    再生医療の基礎シリーズ
    再生医療のための分子生物学　p201-212, コロナ社, 2006
41. 鈴木聡、柳沼克幸、野田哲生
    発がんモデルマウスとがん関連遺伝子の機能解析
    発がんの分子機構と防御　p135-159, 東大出版会, 2006
42. Watanabe S, Horie Y, Suzuki A
    Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma.
    HEPATOLOGY RESEARCH 33, 161-166, 2005
43. 佐々木雄彦、佐々木純子、金保安則、鈴木 聡
    イノシトールリン脂質とマスト細胞機能
    臨床病理, 54(1), 45-50, 2005
44. 佐々木雄彦、佐々木純子、山崎正和、鈴木聡、金保安則
    ホスファチジルイノシトール4,5-二リン酸のコンパートメント化
    細胞工学24(6), 607-611, 2005
45. 佐藤亘、堀江泰夫、渡辺純夫、鈴木聡
    総説シリーズー現代医学の焦点：非アルコール性脂肪性肝炎(NASH)とPTEN遺伝子
    日本臨床63(8), 1475-1483, 2005
46. 渡邊純夫、堀江泰夫、片岡英、佐藤亘、大嶋重敏、鈴木聡
    非アルコール性脂肪性肝炎ー脂肪肝を発症する遺伝子変異マウスを用いた機序の解析ー
    最新医学60(4)、812-824、2005
47. 片岡英、堀江泰夫、渡邊純夫、鈴木聡
    非アルコール性脂肪性肝炎モデル動物としての肝細胞特異的PTEN欠損マウス
    BIO Clinica20(13), 1213-1217, 2005
48. 渡邊純夫、堀江泰夫、片岡英、佐藤亘、大嶋重敏、鈴木聡
    生活習慣病と非アルコール性脂肪性肝炎(NASH)～肝の脂肪化と発癌～
    PROGRESS in MEDICINE25(6), 1651-1656, 2005
49. 堀江泰夫、鈴木聡、片岡英、後藤隆、芳野竜太郎、佐藤亘、渡辺純夫
    脂肪肝から肝がんへ・・・動物モデルから見たNASHの新展開
    日本内科学会雑誌94(5), 990-998, 2005
50. 河原崎哲、夏井美幸、松田幸久、佐々木雄彦、仲野徹、鈴木　聡
    PTEN欠損マウスによる疾患モデルマウス
    分子細胞治療4(2), 151-156, 2005
51. 片岡英、堀江泰夫、佐藤亘、大嶋重敏、三上健一郎、道免孝洋、飯塚政弘、後藤隆、佐々木純子、佐々木雄彦、鈴木聡、渡邊純夫
    DNAマイクロアレイを用いた肝細胞特異的Pten欠損マウスの肝臓における遺伝子発現の検討ー非アルコール性脂肪性肝炎の発症に関わる新たな遺伝子の検索を目的としてー
    秋田医学32(1), 41-51, 2005
52. 堀江泰夫、佐藤亘、大嶋重敏、片岡英、道免孝洋、鈴木聡、渡邊純夫
    NAFLDの成因・NASH病変を呈する遺伝子改変マウスにおける肝発癌機構
    細胞37(9), 352-356, 2005
53. 佐々木雄彦、高須賀俊輔、佐々木純子、金保安則、鈴木聡
    細胞遊走tpホスホイノシタイド動態の遺伝子学的解析
    脂質生化学研究47, 39-42, 2005
54. 鈴木聡
    細胞の運命決定制御
    蛋白質・核酸・酵素50(15), 2012-2013, 2005
55. 堀江泰夫、片岡　英、佐々木雄彦、渡辺純夫、仲野　徹、鈴木　聡
    肝臓における癌抑制遺伝子PTENの機能解析
    細胞療法の基礎と臨床、p146-p156, 2004
56. 渡辺純夫、堀江泰夫、鈴木　聡
    Nonalcoholic Steatohepatitis (NASH)への実験医学的アプローチ
    肝臓45(11), 568-580, 2004
57. Suzuki A, Sasaki T, Mak TW, Nakano T
    Functional analysis of the tumour suppressor gene PTEN in murine B cells and keratinocytes
    BIOCHEMICAL JOURNAL (BIOCHEMICAL SOCIETY TRANSACTION), 32 (2), 362-365, 2004
58. 佐々木雄彦、水野克典、仲野徹、鈴木聡
    PTENホスファターゼとその生体における機能
    細胞工学、23(5), 556-561, 2004
59. 岸本恕征、佐々木雄彦、仲野徹、鈴木聡
    PI3Kキナーゼ関連遺伝子欠損と免疫異常
    Molecular Medicine, 41(5), 58-63, 2004
60. 河原崎哲、濱田浩一、松田幸久、佐々木雄彦、仲野徹、鈴木聡
    PTENとアポトーシス
    Biotherapy, 18(2), 151-160, 2004
61. 堀江泰夫、佐々木雄彦、飯塚政弘、渡邊純夫、鈴木聡
    炎症とアポトーシス
    ２１世紀の胃の炎症学,187-197, メディカルレビュー社,2004
62. 濱田浩一、佐々木雄彦、仲野徹、鈴木聡　
    血液細胞における癌抑制遺伝子PTEN
    血液・腫瘍科, 48(2), 190-195, 2004
63. 岸本恕征、改正恒康、佐々木雄彦、仲野徹、鈴木聡
    ＰＴＥＮによるＢ細胞の分化と機能制御
    臨床免疫　41(2), 121-127, 2004
64. 佐々木雄彦、佐々木純子、鈴木聡
    細胞の極性化、遊走とPI3キナーゼシグナリング
    細胞工学22（8）、754-756、細胞工学, 2003
65. 井上多恵、真鍋求、板見智、佐々木雄彦、仲野徹、鈴木聡
    がん抑制遺伝子ＰＴＥＮと皮膚疾患
    日本皮膚科学会雑誌　113(1), 1641-1650, 2003
66. Kishimoto H, Hamada K, Saunders M, Sasaki T, Nakano T, Mak TW and Suzuki A
    Physiological Functions of PTEN in Various Tissues~ Analysis of the tissue specific PTEN mutant mice ~
    CELL STRUCTURE and FUNCTION 28, 9-19, 2003
67. 木村透、鈴木聡、仲野徹
    始原生殖細胞から全能性細胞へ：テラトーマのEG細胞
    細胞工学　21 (8)、836-838、2002 秀潤社
68. Sasaki T, Suzuki A, Sasaki J, Penninger JM.
    Phosphoinositide 3-kinases in immunity: lessons from knockout mice.
    JOURNAL of BIOCHEMISTRY 131(4):495-501, 2002
69. 佐々木雄彦、山崎正和、鈴木聡
    PI3Kによる極性発生
    細胞骨格と細胞運動，169-174，2002　シュプリンガー・フェアラーク社
70. 鈴木聡、山口麻奈絵、大石美奈子、仲野徹
    癌抑制遺伝子PTENと自己寛容
    Annual Review免疫2002, 201-207,中外医学社,2002
71. Suzuki A, Nakano T
    Development of Hematopoietic Cells from embryonic stem cells
    INTERNATIONAL JOURNAL of HEMATOLOGY 73, 1-5, 2001
72. 佐々木雄彦、鈴木聡
    PI3Kによる細胞遊走の制御
    医学のあゆみ199 (13)，871-875，2001　医歯薬出版
73. 大石美奈子、仲野徹、鈴木聡
    組織特異的なPTENの不活化とT細胞トレランスの破綻
    Molecular Medicine臨時増刊号免疫2002ﾕ 38, 85-93, 2001
74. 鈴木聡、佐々木雄彦、仲野徹
    癌抑制遺伝子PTENの機能解析　生化学的・生理学的な役割
    実験医学別冊‘アポトーシス研究の新たな挑戦’19(13), 1713-1719, 2001
75. 鈴木聡、仲野徹
    PTEN変異と自己免疫疾患
    実験医学別冊‘免疫総集編2001’19(5), 688-693, 2001
76. 山口麻奈絵、鈴木聡、仲野徹
    トレランス形成におけるPTENの意義
    臨床免疫 35(6), 675-682, 2001
77. 佐々木雄彦、鈴木聡、佐々木純子、Josef M.Penninger
    PI3キナーゼとPIホスファターゼの免疫応答、糖代謝、腫瘍形成における役割
    蛋白質核酸酵素46(12) 1820-1829, 2001
78. Akira Suzuki And Tak Wah Mak: CD34. In 'The gene knockout facts Book'(A-H).
    (ed)Tak Wah Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders.
    p 168- 170. Academic Press, San Diego, USA, 1998
79. Akira Suzuki And Tak Wah Mak: BRCA2. In 'The gene knockout facts Book'(A-H).
    (ed)Tak Wah Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders.
    p 95- 96. Academic Press, San Diego, USA, 1998
80. 鈴木聡、須田年生：CD34. ノックアウトマウスデ-タブック、Molecular Medicine 34（臨時増刊号）92-93、1997
81. 鈴木聡、福本学、須田年生：CD34欠損マウス.　実験医学　14、1869-71、1996
82. 高橋隆幸、鈴木聡、福本学、坂根剛：CSF産生腫瘍における肝障害.　日常診療と血液2、1090-93, 1992