大学院案内

業績

業績(2016年~)

英文原著・総説

Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.
Okazaki S, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Boku S, Shimmyo N, Kinoshita M, Inoue E, Ohmori T, Someya T, Sora I.
Prog Neuropsychopharmacol Biol Psychiatry 2018. [Epub ahead of print]

Loss of chromosome Y in blood, but not in brain, of suicide completers.
Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I.
PLoS One 2018;13:e0190667.

Neural basis of major depressive disorder: Beyond monoamine hypothesis.
Boku S, Nakagawa S, Toda H, Hishimoto A.
Psychiatry Clin Neurosci 2018;72:3-12.

Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis.
Boku S, Izumi T, Abe S, Takahashi T, Nishi A, Nomaru H, Naka Y, Kang G, Nagashima M, Hishimoto A, Enomoto S, Duran-Torres G, Tanigaki K, Zhang J, Ye K, Kato S, Männistö PT, Kobayashi K, Hiroi N.
Mol Psychiatry 2017. [Epub ahead of print]

Rare PDCD11 variations are not associated with risk of schizophrenia in Japan.
Hoya S, Watanabe Y, Hishimoto A, Nunokawa A, Kaneko N, Muratake T, Shimmyo N, Otsuka I, Okuda S, Inoue E, Igeta H, Shibuya M, Egawa J, Orime N, Sora I, Someya T.
Psychiatry Clin Neurosci 2017. [Epub ahead of print]

Aberrant telomere length and mitochondrial DNA copy number in suicide completers.
Otsuka I, Izumi T, Boku S, Kimura A, Zhang Y, Mouri K, Okazaki S, Shiroiwa K, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A.
Sci Rep 2017;7:3176.

Association study of MIF promoter polymorphisms with suicide completers in the Japanese population.
Shimmyo N, Hishimoto A, Otsuka I, Okazaki S, Boku S, Mouri K, Horai T, Takahashi M, Ueno Y, Shirakawa O, Sora I.
Neuropsychiatr Dis Treat 2017;13:899-908.

Rare FBXO18 variations and risk of schizophrenia: Whole-exome sequencing in two parent-affected offspring trios followed by resequencing and case-control studies.
Hoya S, Watanabe Y, Hishimoto A, Nunokawa A, Inoue E, Igeta H, Otsuka I, Shibuya M, Egawa J, Sora I, Someya T.
Psychiatry Clin Neurosci 2017;71:562-568.

Optimizing outcomes in clozapine rechallenge following neutropenia using human leukocyte antigen typing: A case report.
Yamaki N, Hishimoto A, Otsuka I, Sasada T, Boku S, Saito T, Yasuda Y, Yamamori H, Ikeda M, Ikeda M, Sora I, Iwata N, Hashimoto R.
Psychiatry Clin Neurosci 2017;71:289-290.

Distinct Roles of Opioid and Dopamine Systems in Lateral Hypothalamic Intracranial Self-Stimulation.
Ide S, Takahashi T, Takamatsu Y, Uhl GR, Niki H, Sora I, Ikeda K.
Int J Neuropsychopharmacol 2017;20:403-409.

Neurocognitive profile of euthymic Japanese patients with bipolar disorder.
Ishisaka N, Shimano S, Miura T, Motomura K, Horii M, Imanaga H, Kishimoto J, Kaneda Y, Sora I, Kanba S.
Psychiatry Clin Neurosci 2017;71:373-382.

The cell cycle-related genes as biomarkers for schizophrenia.
Okazaki S, Boku S, Otsuka I, Mouri K, Aoyama S, Shiroiwa K, Sora I, Fujita A, Shirai Y, Shirakawa O, Kokai M, Hishimoto A.
Prog Neuropsychopharmacol Biol Psychiatry 2016;70:85-91.

Slow synaptic transmission mediated by TRPV1 channels in CA3 interneurons of the hippocampus.
Eguchi N, Hishimoto A, Sora I, Mori M.
Neurosci Lett 2016;616:170-176.

Rare truncating variations and risk of schizophrenia: Whole-exome sequencing in three families with affected siblings and a three-stage follow-up study in a Japanese population.
Watanabe Y, Nunokawa A, Shibuya M, Ikeda M, Hishimoto A, Kondo K, Egawa J, Kaneko N, Muratake T, Saito T, Okazaki S, Shimasaki A, Igeta H, Inoue E, Hoya S, Sugai T, Sora I, Iwata N, Someya T.
Psychiatry Res 2016;235:13-8.

The serum level of NX-DCP-R, but not DCP, is not increased in alcoholic liver disease without hepatocellular carcinoma.
Saito M, Yano Y, Hirano H, Momose K, Mouri K, Hishimoto A, Yoshida M, Azuma T.
Cancer Biomark 2016;16:171-180.

Molecular Histochemistry Identifies Peptidomic Organization and Reorganization Along Striatal Projection Units.
Hishimoto A, Nomaru H, Ye K, Nishi A, Lim J, Aguilan JT, Nieves E, Kang G, Angeletti RH, Hiroi N.
Biol Psychiatry 2016;79:415-420.

Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder.
Toda H, Inoue T, Tsunoda T, Nakai Y, Tanichi M, Tanaka T, Hashimoto N, Takaesu Y, Nakagawa S, Kitaichi Y, Boku S, Tanabe H, Nibuya M, Yoshino A, Kusumi I.
Psychiatry Res 2016;236:142-147.

邦文原著・総説

大塚郁夫, 曽良一郎, 菱本明豊. 自殺既遂の生物学的研究. 日本神経精神薬理学雑誌 36(3):55-61, 2016.

曽良一郎, 菱本明豊.依存症の分子病態解析-報酬系にかかわる受容体と薬物依存-.脳21 19(1):9-12, 2016.

曽良一郎, 蓬莱政, 木村敦, 松山賢一. 脳機能からみたベンゾジアゼピン系薬剤のリスクとベネフィット-依存・耐性および認知機能への影響
. Depression Strategy 7(1):7-9, 2017.

著書

朴秀賢:ブレインサイエンスレビュー2017(廣川信隆編)第11章 幼少期ストレスが成体海馬神経前駆細胞に及ぼす作用とそのメカニズムの解明を通して気分障害の新規治療薬を考える. 227-251頁, クバプロ, 2017.

朴秀賢:Depression Frontier2 うつ病臨床のこんな疑問に答える
脳科学からのアプローチ
(朝田隆,内冨庸介, 熊野宏昭, 野村総一郎, 渡邉義文編)第3章 神経細胞新生とうつ病. 31-40頁, 医薬ジャーナル社, 2016.

大塚郁夫, 菱本明豊:Depression Frontier2 うつ病臨床のこんな疑問に答える
脳科学からのアプローチ
(朝田隆,内冨庸介, 熊野宏昭, 野村総一郎, 渡邉義文編)第5章 自殺の遺伝子研究. 49-60頁, 医薬ジャーナル社, 2016.

過去の業績


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