Shinjyo N., Shigemura M., & Okabe Y.Control of Mucociliary Clearance in Airway Host DefenseInternational Immunology, dxag034 (2026) doi: 10.1093/intimm/dxag034(Online ahead of print) PubMed
2025
Shinjyo N., Kimura H., Yoshihara T., Suzuki J., Yamaguchi M., Kawabata S., & Okabe Y.Aldehyde metabolism governs resilience of mucociliary clearance to air pollution exposureThe Journal of Clinical Investigation, e191276 (2025) PubMed
Nakayama Y., Sasai M., Kuratani A., Okamoto M., Okuzaki D., Yamamoto K., Ono C., Yamaguchi M., Kawabata S., Shinjyo N., Okabe Y., Matsuura Y., Ato M., Yamamoto M.Targeted labeling and depletion of alveolar macrophages using VeDTR mouse technology.iScience, 28(3):111975. doi: 10.1016/j.isci.2025.111975 (2025) PubMed
2024
Okabe Y.Development and organization of omental milky spotsImmunological Reviews, doi: 10.1111/imr.13337 (2024) PubMed
Luca D., Lee S., Hirota K., Okabe Y., Uehori J., Izawa K., Lanz AL., Schütte V., Sivri B., Tsukamoto Y., Hauck F., Behrendt R., Roers A., Fujita T., Nishikomori R., Lee-Kirsch MA., & Kato H.Aberrant RNA sensing in regulatory T cells causes systemic autoimmunityScience Advances, eadk0820. doi: 10.1126/sciadv.adk0820 (2024) PubMed
Okabe Y., & Medzhitov R.How the immune system spots tumorseLife, 3 (2014) PubMed
Okabe Y., & Medzhitov R.Tissue-specific signals control reversible program of localization and functional polarization of macrophagesCell, 157, 832-844 (2014) 【Cell, Best of 2014に選出】 PubMed
2009
Okabe Y., Sano T.(equal contribution), & Nagata S.Regulation of the innate immune response by threonine-phosphatase of Eyes absentNature, 460, 520-524 (2009) PubMed
2008
Okabe Y., Kawane K., & Nagata S.IFN regulatory factor (IRF) 3/7-dependent and –independent gene induction by mammalian DNA that escapes degradationEuropean Journal of Immunology, 38, 3150-3158 (2008) PubMed
2006
Nakaya M., Tanaka M., Okabe Y., Hanayama R., & Nagata S.Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophagesThe Journal of Biological Chemistry, 281, 8836-8842 (2006) PubMed
2005
Okabe Y., Kawane K., Akira S., Taniguchi T., & Nagata S.Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradationThe Journal of Experimental Medicine, 202, 1333-1339 (2005) PubMed
Yoshida H., Okabe Y.(equal contribution), Kawane K., Fukuyama H., & Nagata S.Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNANature Immunology, 6, 49-56 (2005) PubMed
2003
Takahasi K., Suzuki N., Horiuchi M., Mori M., Suhara W., Okabe Y., Fukuhara Y., Terasawa H., Akira S., Fujita T., & Inagaki F.X-ray crystal structure of IRF-3 and its functional implicationsNature Structural & Molecular Biology, 10, 922-927 (2003) PubMed
2001
Iwamura T., Yoneyama M., Koizumi N., Okabe Y., Namiki H., Samuel CE., & Fujita T.PACT, a Double-Stranded RNA Binding Protein Acts as a Positive Regulator for Type I Interferon Gene Induced by Newcastle Disease VirusBiochemical and Biophysical Research Communications, 282, 515-523 (2001) PubMed
Iwamura T., Yoneyama M., Yamaguchi K., Suhara W., Mori W., Shiota K., Okabe Y., Namiki H., & Fujita T.Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathwaysGenes to Cells, 6, 375-388 (2001) PubMed