2022年度

• Matsuda Y, Nakagawa S, Yano I, Masuda S, Imai S, Yonezawa A, Yamamoto T, Sugimoto M, Tsuda M, Tsuzuki T, Omura T, Nakagawa T, Chen-Yoshikawa TF, Nagao M, Date H, Matsubara K. Effect of itraconazole and its metabolite hydroxyitraconazole on the blood concentrations of cyclosporine and tacrolimus in lung transplant recipients. Biol Pharm Bull, 45 (4): 397-402 (2022)
• Kunimitsu Y, Morio K, Hirata S, Yamamoto K, Omura T, Hara T, Harada K, Fujisawa M, Yano I. Effects of proton pump inhibitors on survival prognosis in patients with metastatic or unresectable urothelial carcinoma treated with pembrolizumab. Biol Pharm Bull, 45(5): 590-595 (2022)
• Kakei Y, Ioroi T, Ito T, Okazaki Y, Hasegawa T, Yano I, Akashi M. Efficacy of ibuprofen gargle for postoperative pain after mandibular third molar extraction: protocol for a phase II, placebo-controlled, double-blind, randomized crossover trial. JMIR Res Protoc, 11(5): e35533 (2022)
• Morio K, Kurata Y, Kawaguchi-Sakita N, Shiroshita A, Kataoka Y. Efficacy of Metformin in Patients with Breast Cancer Receiving Chemotherapy or Endocrine Therapy: Systematic Review and Meta-analysis. Ann Pharmacother, 56(3): 245-255 (2022)
• Kimura T, Fujita M, Shimizu M, Sumiyoshi K, Bansho S, Yamamoto K, Omura T, Yano I. Effectiveness of pharmacist intervention for deprescribing potentially inappropriate medications: a prospective observational study. J Pharm Health Care Sci, 8:12 (2022)
• Katada Y, Nakagawa S, Itohara K, Suzuki T, Kato R, Endo H, Sugimoto M, Yonezawa A, Nakagawa T, Ohsumi A, Nakajima D, Date H, Terada T. Association between time in therapeutic range of tacrolimus blood concentration and acute rejection within the first three months after lung transplantation. J Pharm Health Care Sci, 8:25 (2022)
• Takaichi M, Osawa K, Nomoto R, Nakanishi N, Kameoka M, Miura M, Shigemura K, Kinoshita S, Kitagawa K, Uda A, Miyara T, Mertaniasih NM, Hadi U, Raharjo D, Yulistiani R, Fujisawa K, Kuntaman K, Shirakawa T. Antibiotic resistance in non-typhoidal Salmonella enterica strains isolated from chicken meat in Indonesia. Pathogens, 11(5): 543 (2022)
• Yamamoto K, Ioroi T, Shinomiya K, Yoshida A, Harada K, Fujisawa M, Omura T, Ikemi Y, Nakagawa S, Yonezawa A, Ogawa O, Matsubara K, Iwamoto T, Nishikawa K, Hayashi S, Tohara D, Murakami Y, Motoshima T, Jono H, Yano I. STAT3 polymorphism associates with mTOR inhibitor-induced interstitial lung disease in patients with renal cell carcinoma. Oncol Res, 29(1):11-23 (2022)
• Yamamoto K, Nishiyama S, Kunisada M, Iida M, Ito T, Ioroi T, Makimoto H, Omura T, Harada K, Fujisawa M, Nishigori C, Yano I. Safety and Efficacy of Bis-Glyceryl Ascorbate as Prophylaxis for Hand-Foot Skin Reaction: A Single-Arm, Open-Label Phase I/II study (DGA study). Oncologist, 27(5): e384-e392 (2022)
• Shigetsura Y, Imai S, Endo H, Shimizu Y, Ueda K, Murai T, Itohara K, Nakagawa S, Yonezawa A, Ikemi Y, Fukatsu S, Kitada N, Terada T, Nakagawa T, Matsubara K. Assessment of Suvorexant and Eszopiclone as Alternatives to Benzodiazepines for Treating Insomnia in Patients With Major Depressive Disorder. Clin Neuropharmacol, 45(3): 52-60 (2022)
• Masui S, Yonezawa A, Yokoyama K, Iwamoto N, Shimada T, Onishi A, Onizawa H, Fujii T, Murakami K, Murata K, Tanaka M, Nakagawa S, Hira D, Itohara K, Imai S, Nakagawa T, Hayakari M, Matsuda S, Morinobu A, Terada T, Matsubara K. N-terminus of Etanercept is Proteolytically Processed by Dipeptidyl Peptidase-4. Pharm Res, 39(10): 2541-2554 (2022)
• Ogihara T, Kagawa M, Yamanaka R, Imai S, Itohara K, Hira D, Nakagawa S, Yonezawa A, Ito M, Nakagawa T, Terada T, Matsubara K. Preparation and pharmaceutical properties of Hangeshashinto oral ointment and its safety and efficacy in Syrian hamsters with 5-fluorouracil-induced oral mucositis. J Nat Med, 77(1): 53-63 (2022)
• Itohara K, Yano I, Nakagawa S, Sugimoto M, Hirai M, Yonezawa A, Imai S, Nakagawa T, Hira D, Ito T, Hata K, Hatano E, Terada T, Matsubara K. Population pharmacokinetics of everolimus in adult liver transplant patients: Comparison to tacrolimus disposition and extrapolation to pediatrics. Clin Transl Sci, 15(11): 2652-2662 (2022)
• Ikuta K, Nakagawa S, Yamawaki C, Itohara K, Hira D, Imai S, Yonezawa A, Nakagawa T, Sakuragi M, Sato N, Uchino E, Yanagita M, Terada T. Use of proton pump inhibitors and macrolide antibiotics and risk of acute kidney injury: a self-controlled case series study. BMC Nephrol, 23(1): 383 (2022)
• Nakagawa S, Shimazaki A, Funakoshi T, Yonezawa A, Kataoka S, Horimatsu T, Hira D, Itohara K, Imai S, Nakagawa T, Matsubara T, Yanagita M, Muto M, Matsubara K, Terada T. Effect of Severe Renal Dysfunction on the Plasma Levels of DNA-Reactive Platinum after Oxaliplatin Administration. Biol Pharm Bull, 46(2): 194-200 (2023)
• Kitahiro Y, Ioroi K, Kakei Y, Yamashita J, Kimoto A, Hasegawa T, Morioka A, Yamamoto K, Akashi M, Yano I. Efficacy and Long-Term Safety of Ibuprofen Gargle for Oral Lichen Planus: A Study Protocol of Randomized Crossover and Long-Term Extension Trials. Methods Protoc, 6(7): 1-11 (2023)
• Enomoto D, Yamamoto K, Matsumoto Y, Morioka A, Omura T, Komatsu S, Yano Y, Fukumoto T, Yano I. ALBI grade is a predictive factor of lenvatinib treatment discontinuation due to adverse events in hepatocellular carcinoma. Anticancer Res, 43(3): 1317-1323 (2023)

2021年度

• Saito J, Nadatani N, Setoguchi M, Nakao M, Kimura H, Sameshima M, Kobayashi K, Matsumoto H, Yoshikawa N, Yokoyama T, Takahashi H, Suenaga M, Watanabe R, Imai K, Obara M, Hashimoto M, Yamamoto K, Fujiwara N, Sakata W, Nagai H, Enokihara T, Katayama S, Takahashi Y, Araki M, Iino K, Akiyama N, Katsu H, Fushimi K, Takeda T, Torimoto M, Kishi R, Mitsuya N, Kihara R, Hasegawa Y, Hamada Y, Kimura T, Wada M, Tanzawa A, Yamatani A. Potentially harmful excipients in neonatal medications: a multicenter nationwide observational study in Japan. J Pharm Health Care Sci, 7(1):23 (2021)
• Koyanagi M, Imai S, Matsumoto M, Iguma Y, Kawaguchi-Sakita, N, Kotake T, Iwamitsu Y, Ntogwa M, Hiraiwa R, Nagayasu K, Saigo M, Ogihara T, Yonezawa A, Omura T, Nakagawa S, Nakagawa T, Matsubara K. Pro-nociceptive roles of Schwann cell-derived galectin-3 in taxane-induced peripheral neuropathy. Cancer Res, 81(8): 2207-2219 (2021)
• Nakayama Y, Takara K, Minegaki T, Yamamoto K, Omura T, Yano I. Induction of Cross-resistance to ABCB1 Substrates in Venetoclax-resistant Human Leukemia HL60 Cells. Anticancer Res, 41(9):4239-4248 (2021)
• Uda A, Shigemura K, Kitagawa K, Osawa K, Kusuki Mari, Yan Y, Yano I, Miyara T. Effect of Antimicrobial Stewardship on Oral Quinolone Use and Resistance Patterns over 8 Years (2013-2020). Antibiotics, 10(11):1426 (2021)
• Itohara K, Yano I, Nakagawa S, Yonezawa A, Omura T, Imai S, Nakagawa T, Sawada A, Kobayashi T, Tochio A, Sakai K, Taura K, Ogawa O, Matsubara K. Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients. Drug Metab Pharmacokinet, 42(2):100423 (2022)
• Ito T, Yamamoto K, Furukawa J, Harada K, Fujisawa M, Omura T, Yano I. Association of sunitinib concentration and clinical outcome in patients with metastatic renal cell carcinoma treated with a 2-week-on and 1-week-off schedule. J Clin Pharm Ther, 47(1):81-88 (2022)
• Onishi R, Shigemura K, Osawa K, Yang Y, Maeda K, Fang S, Sung S, Onuma K, Uda A, Miyara T, Fujisawa M. The Antimicrobial Resistance Characteristics of Imipenem-Non-Susceptible, Imipenemase-6-Producing Escherichia coli. Antibiotics, 11(1):32 (2022)
• Uda A, Ebisawa K, Sakon H, Kusuki M, Izuta R, Yahata M, Yano I, Miyara T. Sustained Improvements in Antimicrobial Therapy and Clinical Outcomes Following a Pharmacist-Led Antimicrobial Stewardship Intervention: Uncontrolled Before-After Study. J Clin Med, 11(3):566 (2022)
• Uda A, Onuma K, Shigemura K, Kitagawa K, Yan Y, Osawa K, Yano I, Miyara T. Impact of Cefazolin Shortage on Clinical Outcomes of Adult Patients with Bacteremia Caused by Methicillin-Susceptible Staphylococcus aureus in a Tertiary Care University Hospital. Antibiotics, 10(10):1247 (2022)
• Omura T, Nomura L, Watanabe R, Nishiguchi H, Yamamoto K, Imai S, Nakagawa S, Itohara K, Yonezawa A, Nakagawa T, Kunimasa J, Yano I, Matsubara K. MicroRNA-101 Regulates 6-Hydroxydopamine-Induced Cell Death by Targeting Suppressor/Enhancer Lin-12-Like in SH-SY5Y Cells. Front Mol Neurosci, 14(748026) (2022)

2020年度

• Jin C, Yonezawa A, Yoshimatsu H, Imai S, Koyanagi M, Yamanishi K, Nakagawa S, Itohara K, Omura T, Nakagawa T, Nagai J, Matsubara K. Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice. Sci Rep, 10(1):18443 (2020)
• Ioroi T, Kiyota N, Imamura Y, Tanda M, Aoki S, Okuno M, Yamamoto K, Sasaki R, Nibu K, Minami H, Hirai M, Yano I. Ibuprofen Gargle for Chemo- or Chemoradiotherapy-Induced Oral Mucositis: A Feasibility Study. J Pharm Health Care Sci, 6:12 (2020)
• Yamashita K, Ogihara T, Hayashi M, Nakagawa T, Ishizaki Y, Kume M, Yano I, Niigata R, Hiraoka J, Yasui H, Nakamura T. Association between dexamethasone treatment and alterations in serum concentrations of trace metals. Pharmazie, 75(5): 218-222 (2020)
• Ito T, Yamamoto K, Ogawa S, Furukawa J, Harada K, Fujisawa M, Omura T, Yano I. Model-based assessment of pharmacokinetic changes of sunitinib, tacrolimus, and everolimus in a patient with metastatic renal cell carcinoma after renal transplantation. Drug Metab Pharmacokinet, 35(5):405-409 (2020)
• Kondo M, Nakagawa S, Orii S, Itohara K, Sugimoto M, Omura T, Sato Y, Imai S, Yonezawa A, Nakagawa T, Matsubara K. Share Association of Initial Trough Concentrations of Vancomycin with Outcomes in Pediatric Patients with Gram- Positive Bacterial Infection. Biol Pharm Bull. 43(10):1463-1468 (2020)
• Ntogwa M, Imai S, Hiraiwa R, Koyanagi M, Matsumoto M, Ogihara T, Nakagawa S, Omura T, Yonezawa A, Nakagawa T, Matsubara K. Schwann cell-derived CXCL1 contributes to human immunodeficiency virus type 1 gp120-induced neuropathic pain by modulating macrophage infiltration in mice. Brain Behav Immun, 88:325- 339 (2020)
• Kusumoto J, Uda A, Kimura T, Furudoi S, Yoshii R, Matsumura M, Miyara T, Akashi
  M. Effect of educational intervention on the appropriate use of oral antimicrobials in oral and maxillofacial surgery: a retrospective secondary data analysis. BMC Oral Health, 21(1):20 (2021)
• Uda A, Shigemura K, Kitagawa K, Osawa K, Onuma K, Yan Y, Nakano Y, Nishioka T, Fujisawa M, Yano I, Miyara T. Risk Factors for the Acquisition of Enterococcus faecium Infection and Mortality in Patients with Enterococcal Bacteremia: A 5-year Retrospective Analysis in a Tertiary Care University Hospital. Antibiotics, 10(1)E64, (2021)
• Yamamoto J, Omura T, Kasamo S, Yamamoto S, Kawata M, Yonezawa A, Taruno Y, Endo H, Aizawa H, Sawamoto N, Matsubara K, Takahashi R, Tasaki Y. Impact of the catechol-O-methyltransferase Val158Met polymorphism on the pharmacokinetics of L-dopa and its metabolite 3-O-methyldopa in combination with entacapone. J Neural Transm (Vienna) , 128(1):27-36 (2021)
• Morio K, Yamamoto K, Yano I. Relationship Between Tramadol Response and Cancer Cachexia: A Retrospective Cohort Study. Am J Hosp Palliat Care, 38(3):276- 282 (2021)
• Yoshida A, Yamamoto K, Ishida T, Omura T, Itoh T, Nishigori C, Sakane T, Yano I. Sunitinib decreases the expression of KRT6A and SERPINB1 in 3D human epidermal models. Exp Dermatol, 30(3):337-346 (2021)

2019年度

• Katada Y, Nakagawa S, Nishimura A, Sato YK, Taue H, Matsumura K, Yamazaki　K, Minakata K, Yano I, Omura T, Imai S, Yonezawa A, Sato Y, Nakagawa T,　Minatoya K, Matsubara K.
  Effects of fasting on warfarin sensitivity index in patients undergoing cardiovascular surgery.
  Eur J Clin Pharmacol, 75(4): 561-568(2019)
• Yonezawa A, Otani Y, Kitano T, Mori M, Masui S, Isomoto Y, Tsuda M, Imai S, Ikemi Y, Denda M, Sato Y, Nakagawa S, Omura T, Nakagawa T, Yano I, Hayakari M, Takaori-Kondo A, Matsubara K.
  Concentration and glycoform of rituximab in plasma of patients with B-cell non-Hodgkin's lymphoma.
  Pharm Res, 36(6): 82(2019)
• Yoshida M, Kojima H, Uda A, Haraguchi T, Ozeki M, Kawasaki I, Yamamoto K, Yano I, Hirai M, Uchida T.
  Bitterness-masking effects of different beverages on zopiclone and eszopiclone tablets.
  Chem Pharm Bull, 67 (5): 404-409 (2019)
• Chayahara N, Mukohara T, Tachihara M, Fujishima Y, Fukunaga A, Washio K, Yamamoto M, Nakata K, Kobayashi K, Takenaka K, Toyoda M, Kiyota N, Tobimatsu K, Doi H, Mizuta N, Marugami N, Kawaguchi A, Nishigori C, NishimuraY, MinamiH.
  Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti-Epidermal Growth Factor Receptor-Induced Acne-Like Rash: A Randomized Left-Right Comparative Evaluation (APPEARANCE).
  Oncologist, 24(7):885-e413(2019)
• Itohara K, Yano I, Tsuzuki T, Uesugi M, Nakagawa S, Yonezawa A, Okajima H, Kaido T, Uemoto S, Matsubara K.
  A Minimal PBPK Model for Tacrolimus in Living-Donor Liver Transplantation: Perspectives related to Liver Regeneration and CYP3A5 Genotype.
  CPT Pharmacometrics Syst Pharmacol, 8(8):587-595(2019)
• Yamamoto K, Ioroi T, Harada K, Nishiyama S, Nishigori C, Yano I.
  Safety and efficacy of bis-glyceryl ascorbate (Amitose DGA) to prevent hand-foot skin reaction in patients with renal cell carcinoma receiving sunitinib therapy (DGAstudy): study protocol for a phase I/II, uncontrolled, single-arm, open-label trial.
  JMIR Res Protoc, 8(8):e14636 (2019)
• Yamamoto K, Fukushima S, Mishima Y, Hashimoto M, Yamakawa K, Fujioka K, Iijima K, Yano I.
  Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model.
  Drug Metab Pharmacokinet, 34:400-402 (2019)
• Uda A, Kimura T, Nishimura S, Ebisawa K, Ohji G, Kusuki M, Yahata M, Izuta R, Sakaue T, Nakamura T, Koike C, Tokimatsu I, Yano I, Iwata K, Miyara T.
  Efficacy of educational intervention on reducing the inappropriate use of oral thirdgeneration cephalosporins.
  Infection, 47(6):1037-1045, 2019.
• Uda A, Tokimatsu I, Osawa K, Shigemura K, Kimura T, Koike C, Nishioka T, Nakamura T, Yano I.
  Antibiotic de-escalation therapy in patients with communityacquired nonbacteremic pneumococcal pneumonia.
  Int J Clin Pharm, 41(6):1611-1617 (2019)
• Kimura T, Ogura F, Kukita Y, Takahashi T, Yamamoto Y, Ioroi T, Yano I.
  Efficacy of pharmacists' assessment and intervention based on Screening Tool for Older Persons' Appropriate Prescriptions for Japanese compared with Screening Tool for Older Persons' Appropriate Prescriptions criteria version 2 in elderly patients with cardiovascular disease.
  Geriatrics Gerontology Int, 19(11):1101-1107 (2019)
• Ogihara T, Nakagawa T, Hayashi M, Koyanagi M, Yonezawa A, Omura T, Nakagawa S, Kitada N, Imai S, Matsubara K.
  Improvement of peripheral vascular impairment by a phosphodiesterase type 5 inhibitor tadalafil prevents oxaliplatininduced peripheral neuropathy in mice.
  J Pharmacol Sci,141 (4):131-138 (2019)
• Negoro H, Goto T, Akamatsu S, Terada N, Kobayashi T, Matsui Y, Yamamoto T, Omura T, Yonezawa A, Matsubara K, Ogawa O.
  Add-on effects of tadalafil in tamsulosin-treated patients with small benign prostatic enlargement: A randomized, placebo-controlled, double-blind, crossover study.
  Neurourol Urodynam, 39(1):237-242 (2020)
• Fujiya M, Ueno N, Kashima S, Tanaka K, Sakatani A, Ando K, Moriichi K, Konishi H, Kamiyama N, Tasaki Y, Omura T, Matsubara K, Taruishi M, Okumura T.
  Longchain polyphosphate is a potential agent for inducing mucosal healing of the colon in ulcerative colitis.
  Clin Pharmacol Ther, 107(2):452-461 (2020)
• Zhang Y, Yonezawa A, Nakagawa S, Imai S, Denda M, Omura T, Nakagawa T, Matsubara K.
  Cisplatin, rather than oxaliplatin, increases paracellular permeability of LLC-PK1 cells via activating protein kinase C. Drug Metab Pharmacokinet.
  35(1):111-116 (2020)
• Uda A, Shigemura K, Kitagawa K, Osawa K, Onuma K, Inoue S, Kotani J, Yan Y, Nakano Y, Nishioka T, Yano I, Miyara T, Fujisawa M.
  How does antimicrobial stewardship affect inappropriate antibiotic therapy in urological patients?
  Antibiotics, 9(2):63 (2020)

2018年度

• Yoshimura K, Yano I, Yamamoto T, Kondo T, Kawanishi M, Isomoto Y, Yonezawa A, Takaori-Kondo A, Matsubara K
  Pharmacokinetic and pharmacodynamic markers of mycophenolic acid associated with effective prophylaxis for acute graft-versus-host disease and neutrophil engraftment in cord blood transplant patients.
  Biol Blood Marrow Transplant, 24(7):1441-1448 (2018)

• Yamamoto K, Hara T, Nakagawa T, Hirai M, Miyake H, Fujisawa M, Yano I
  Association of Expression Levels or Activation Status of STAT3 with Treatment Outcomes of Sunitinib in Patients with Renal Cell Carcinoma.
  Target Oncol, 13(3):371-378 (2018)
• Iwasaki M, Yano I, Fukatsu S, Hashi S, Yamamoto Y, Sugimoto M, Fukudo M, Masuda S, Nakagawa S, Yonezawa A, Kaido T, Uemoto S, Matsubara K
  Pharmacokinetics and pharmacodynamics of once-daily tacrolimus compared with twice-daily tacrolimus in the early stage after living donor liver transplantation.
  Ther Drug Monit, 40(6):675-681 (2018)
• Omura T, Sasaoka M, Hashimoto G, Imai S, Yamamoto J, Sato Y, Nakagawa S, Yonezawa A, Nakagawa T, Yano I, Tasaki Y, Matsubara K
  Oxicam-derived non-steroidal anti-inflammatory drugs suppress 1-methyl-4-phenyl pyridinium-induced cell death via repression of endoplasmic reticulum stress response and mitochondrial dysfunction in SH-SY5Y cells.
  Biochem Biophys Res Commun, 503(4):2963-2969, (2018)
• Omura T, Matsuda H, Nomura L, Imai S, Denda M, Nakagawa S, Yonezawa A, Nakagawa T, Yano I, Matsubara K
  Ubiquitin ligase HMG-CoA reductase degradation 1 (HRD1) prevents cell death in a cellular model of Parkinson's disease.
  Biochem Biophys Res Commun, 506(3): 516-521 (2018).
• Ito T, Yamamoto K, Ohsawa F, Otsuka I, Hishimoto A, Sora I, Hirai M, Yano I
  Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study.
  J Pharm Health Care Sci, 4:28 (2018)
• Kitagawa K, Shigemura K, Yamamichi F, Osawa K, Uda A, Koike C, Tokimatsu I, Shirakawa T, Miyara T, Fujisawa M
  Bacteremia complicating urinary tract infection by Pseudomonas aeruginosa: Mortality risk factors.
  Int J Urol, 26(3):358-362 (2018)
• Yokoyama N, Ishimura T, Oda T, Ogawa S, Yamamoto K, Fujisawa M
  Association of the PCK2 gene polymorphism with new-onset glucose intolerance in Japanese kidney transplant recipients
  Transplant Proc, 50(4):1045-9 (2018)

2017年度

• Mizuta N, Nakagawa T, Yamamoto K, Nishioka T, Kume M, Makimoto H, Yano I, Minami H, HiraiM.
  Compatibility and stability of nab-paclitaxel in combination with other drugs.
  Kobe J Med Sci, 63(1): E9-E16 (2017)
• Katada Y, Nakagawa S, Minakata K, Odaka M, Taue H, Sato Y, Yonezawa A, Kayano Y, Yano I, Nakatsu T, Sakamoto K, Uehara K, Sakaguchi H, Yamazaki K, Minatoya K, Sakata R, Matsubara K.
  Efficacy of a protocol-based pharmacotherapy management on anticoagulation with warfarin for patients with cardiovascular surgery.
  J Clin Pharmacol Ther, 42(5):591-597 (2017)
• Yamamoto K, Shichiri H, Ishida T, Kaku K, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Bito T, Nishigori C, Yano I, Hirai M.
  Effects of ascorbyl-2-phosphate magnesium on human keratinocyte toxicity and pathological changes by sorafenib.
  Bio Pharm Bull, 40(9):1530-1536 (2017)
• Hanai A, Ishiguro, H, Takashi. Sozu T, Tsuda M, Yano I, Nakagawa T, Imai S, Hamabe Y, Toi M, Arai H, Tsuboyama T.
  Effects of cryotherapy on objective and subjective symptoms of paclitaxel-induced neuropathy: Prospective self-controlled trial.
  J Natl Cancer Inst, 110(2): djx178 (2017)
• Yoshimura K, Yano I, Yamamoto T, Kawanishi M, Isomoto Y, Yonezawa A, Kondo T, Takaori-Kondo A, Matsubara K.
  Population pharmacokinetics and pharmacodynamics of mycophenolic acid using the prospective data in patients undergoing hematopoietic stem cell transplantation.
  Bone Marrow Transplant, 53(1):44-51 (2018).
• Watanabe A, Yamamoto K, Ioroi T, Hirata S, Harada K, Miyake H, Fujisawa M, Nakagawa T, Yano I, Hirai M.
  Association of Single Nucleotide Polymorphisms in STAT3, ABCB1, and ABCG2 with Stomatitis in Patients with Metastatic Renal Cell Carcinoma Treated with Sunitinib: A Retrospective Analysis in Japanese Patients.
  Biol Pharm Bull, 40(4):458-464 (2017)
• Shichiri H, Yamamoto K, Tokura M, Ishida T, Uda A, Bito T, Nishigori C, Nakagawa T, Hirano T, Yano I, Hirai M.
  Prostaglandin E1 reduces the keratinocyte toxicity of sorafenib by maintaining signal transducer and activator of transcription 3 (STAT3) activity and enhancing the cAMP response element binding protein (CREB) activity.
  Biochem Biophys Res Commun, 485(2):227-233 (2017)
• Ioroi T, Furukawa J, Kume M, Hirata S, Utsubo Y, Mizuta N, Miyake H, Fujisawa M, Hirai M.
  Phase II study of palonosetron, aprepitant and dexamethasone to prevent nausea and vomiting induced by multiple-day emetogenic chemotherapy.
  Support Care Cancer, doi: 10.1007/s00520-017-3967-2 (2017)
• Kimura T, Uda A, Sakaue T, Yamashita K, Nishioka T, Nishimura S, Ebisawa K, Nagata M, Ohji G, Nakamura T, Koike C, Kusuki M, Ioroi T, Mukai A, Abe Y, Yoshida H, Hirai M, Arakawa S, Yano I, Iwata K, Tokimatsu I.
  Long-term efficacy of comprehensive multidisciplinary antibiotic stewardship programs centered on weekly prospective audit and feedback. Infection. doi:10.1007/s15010-017-1099-8 (2017)

2016年度

• Ito S, Yano I, Hashi S, Tsuda M, Sugimoto M, Yonezawa A, Ikeda A, Matsubara K.
  Population pharmacokinetic modeling of levetiracetam in pediatric and adult patients with epilepsy by using routinely monitored data.
  Ther Drug Monit, 38(3):371-8 (2016)
• Onoue H, Yano I, Tanaka A, Itohara K, Hanai A, Ishiguro H, Motohashi H, Masuda S, Matsubara K.
  Significant effect of age on docetaxel pharmacokinetics in Japanese female breast cancer patients by using the population modeling approach.
  Eur J Clin Pharmacol, 72(6):703-10 (2016)
• Yoshimatsu H, Yonezawa A, Yamanishi K, Yao Y, Sugano K, Nakagawa S, Imai S, Omura T, Nakagawa T, Yano I, Masuda S, Inui K, Matsubara K.
  Disruption of Slc52a3 gene causes neonatal lethality with riboflavin deficiency in mice.
  Sci Rep, 6:27557 (2016)
• Zhou Z, Yano I, Odaka S., Morita Y, Shizuta S, Hayano M, Kimura T, Akaike A, Inui K, Matsubara K.
  Effect of vitamin K2 on the anticoagulant activity of warfarin during the perioperative period of catheter ablation: Population analysis of retrospective clinical data.
  J Pharm Health Care Sci , 2,17 (2016)
• Tanaka A, Yano I, Shinsako K, Sato E, Fukudo M, Masuda S, Yamasaki T, Kamba T, Ogawa O, Matsubara K.
  Population pharmacokinetics of everolimus in relation to clinical outcomes in patients with advanced renal cell carcinoma.
  Ther Drug Monit , 38:663-9 (2016)
• Sato S, Jung H, Nakagawa T, Pawlosky R, Takeshima T, Lee WR, Sakiyama H, Laxman S, Wynn RM, Tu BP, MacMillan JB, De Brabander JK, Veech RL, Uyeda K.
  Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
  J Biol Chem , 291:10515-27 (2016)
• Totsuka R, Kondo T, Matsubara S, Hirai M, Kurebayashi Y.
  Effects of VLA-1 Blockade on Experimental Inflammation in Mice.
  Kobe J Med Sci , 62(2):E27-37 (2016)
• Mori H, Arita K, Yamaguchi T, Hirai M, Kurebayashi Y.
  Effects of Topical Application of Betamethasone on Imiquimod-induced Psoriasis-like Skin Inflammation in Mice.
  Kobe J Med Sci, 62(4):E79-E88 (2016)
• Nakamura T, Takahashi M, Niigata R, Yamashita K, Kume M, Hirai M, Yasui H.
  Changes in blood concentrations of trace metals in cancer patients receiving cisplatin-based chemotherapy.
  Biomed Rep. 5:737-744 (2016)
• Kimura T, Ogura F, Yamamoto K, Uda A, Nishioka T, Kume M, Makimoto H, Yano I, Hirai M.
  Potentially inappropriate medications in elderly Japanese patients: effects of pharmacists' assessment and intervention based on Screening Tool of Older Persons' Potentially Inappropriate Prescriptions criteria ver.2.
  J Clin Pharm Ther. 42:209-214 (2017)
• Otani Y, Yonezawa A, Tsuda M, Imai S, Ikemi Y, Nakagawa S, Omura T, Nakagawa T, Yano I, Matasubara K.
  Time-dependent structural alteration of rituximab analyzed by LC/TOF-MS after a systemic administration to rats.
  PLoS One , 12(1):e0169588 (2017)
• Takeuchi M, Yano I, Ito S, Sugimoto M, Yamamoto S, Yonezawa A, Ikeda A, Matsubara K.
  Population pharmacokinetics of topiramate in Japanese pediatric and adult patients with epilepsy using routinely monitored data.
  Ther Drug Monit , 39:124-31 (2017)
• Kawara F, Fujita T, Morita Y, Uda A, Masuda A, Saito M, Ooi M, Ishida T, Kondo Y, Yoshida S, Okuno T, Yano Y, Yoshida M, Kutsumi H, Hayakumo T, Yamashita K, Hirano T, Hirai M, Azuma T.
  Factors ssociated with residual gastroesophageal reflux disease symptoms in patients receiving proton pump inhibitor maintenance therapy.
  World J Gastroenterol , 23(11):2060-2067 (2017)

2015年度

• Ioroi T, Kakuma T, Sakashita A, Miki Y, Ohtagaki K, Fujiwara Y, Utsubo Y, Nishimura Y, Hirai M.
  Data analysis methods for assessing palliative care interventions in one-group pre?post studies.
  SAGE Open Medicine, 3:2050312115621313(2015)

• Mizumoto A, Yamamoto K, Nakayama Y, Takara K, Nakagawa T, Hirano T, Hirai M.
  Induction of epithelial-mesenchymal transition via activation of epidermal growth factor receptor constitutes to sunitinib resistance in human renal cell carcinoma cell lines.
  J Pharmacol Exp Ther. 355(2):152-8 (2015)

• Yamamoto K, Shichiri H, Uda A, Yamashita K, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Hirai M.
  Apoptotic Effects of the Extracts of Cordyceps militaris via Erk Phosphorylation in a Renal Cell Carcinoma Cell Line.
  Phytother Res. 29(5):707-13 (2015)

• Yamamoto K, Ioroi T, Kanaya K, Shinomiya K, Komoto S, Hirata S, Harada K, Watanabe A, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Miyake H, Fujisawa M, Hirai M.
  STAT3 polymorphism rs4796793 may be a predictive factor of tumor response to multiple tyrosine kinase inhibitors in metastatic renal cell carcinoma in Japanese population.
  Med Oncol, 33(3):24 (2016)

• Yamamoto K, Shinomiya K, Ioroi T, Hirata S, Harada K, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Bito T, Nishigori C, Miyake H, Fujisawa M, Hirai M.
  Association of single nucleotide polymorphisms in STAT3 with hand-foot skin reactions in patients with metastatic renal cell carcinoma treated with multiple tyrosine kinase inhibitors: a retrospective analysis in Japanese patients.
  Target Oncol. 11(1):93-9 (2016)

2014年度

• Yamamoto K, Mizumoto A, Nishimura K, Uda A, Mukai A, Yamashita K, Kume M, Makimoto H, Bito T, Nishigori C, Nakagawa T, Hirano T, Hirai M.
  Association of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3).
  PLoS One. 2014 Jul 11;9(7):e102110.

• Seki K, Tsuduki Y, Ioroi T, Yamane M, Yamauchi H, Shiraishi Y, Ogawa T, Nakata I, Nishiguchi K, Matsubayashi T, Takakubo Y, Yamamori M, Kuwahara A, Okamura N, Sakaeda T.
  Serum lactate dehydrogenase levels as a predictive marker of oxaliplatin-induced hypersensitivity reactions in Japanese patients with advanced colorectal cancer.
  Int J Med Sci. 2014 Apr 26;11(6):641-5.

• Kawauchi S, Nakamura T, Yasui H, Nishikawa C, Miki I, Inoue J, Horibe S, Hamaguchi T, Tanahashi T, Mizuno S.
  Intestinal and hepatic expression of cytochrome P450s and mdr1a in rats with indomethacin-induced small intestinal ulcers.
  Int J Med Sci. 2014 Sep 13;11(12):1208-17.
• Minegaki T, Kuwahara A, Yamamori M, Nakamura T, Okuno T, Miki I, Omatsu H, Tamura T, Hirai M, Azuma T, Sakaeda T, Nishiguchi K.
  Genetic polymorphisms in SLC23A2 as predictive biomarkers of severe acute toxicities after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.
  Int J Med Sci. 2014 Feb 7;11(4):321-6.

2013年度

• Yamamoto K, Uda A, Mukai A, Yamashita K, Kume M, Makimoto H, Bito T, Nishigori C, Hirano T, Hirai M.
  Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition.
  J Exp Clin Cancer Res. 2013 Oct 25;32:83.

• Omatsu H, Kuwahara A, Yamamori M, Fujita M, Okuno T, Miki I, Tamura T, Nishiguchi K, Okamura N, Nakamura T, Azuma T, Hirano T, Ozawa K, Hirai M.
  TNF-α -857C>T genotype is predictive of clinical response after treatment with definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.
  Int J Med Sci. 2013 Oct 15;10(12):1755-60.
• Sai K, Hanatani T, Azuma Y, Segawa K, Tohkin M, Omatsu H, Makimoto H, Hirai M, Saito Y.
  Development of a detection algorithm for statin-induced myopathy using electronic medical records.
  J Clin Pharm Ther. 2013 Jun;38(3):230-5.
• Nakagawa T, Ge Q, Pawlosky R, Wynn RM, Veech RL, Uyeda K.
  Metabolite regulation of nucleo-cytosolic trafficking of carbohydrate response element-binding protein (ChREBP): role of ketone bodies.
  J Biol Chem. 2013 Sep 27;288(39):28358-67.
• Ishihara K, Takahashi N, Komoto N, Yoshikawa C, Fukumoto S, Ide S, Kimura T, Ozawa K.
  Serotonergic modulation of neuronal activity in the nucleus accumbens following repeated methamphetamine administration in rats.
  J Pharmacol Sci. 2013;123(2):140-6.

2012年度

• Kume M, Yasui H, Yoshikawa Y, Horinouchi M, Higashiguchi K, Kobayashi Y, Kuroda D, Hirano T, Hirai M, Nakamura T.
  Transient elevation of serum cystatin C concentrations during perioperative cisplatin-based chemotherapy in esophageal cancer patients.
  Cancer Chemother Pharmacol. 2012 Jun;69(6):1537-44.

• Miki I, Nakamura T, Kuwahara A, Yamamori M, Nishiguchi K, Tamura T, Okuno T, Omatsu H, Mizuno S, Hirai M, Azuma T, Sakaeda T.
  THRB genetic polymorphisms can predict severe myelotoxicity after definitive chemoradiotherapy in patients with esophageal squamous cell carcinoma.
  Int J Med Sci. 2012;9(9):748-5.
• Yamawaki C, Takahashi M, Takara K, Kume M, Hirai M, Yasui H, Nakamura T.
  Effect of dexamethasone on extracellular secretion of cystatin C in cancer cell lines.
  Biomed Rep. 2013 Jan;1(1):115-118.
• Sato Y, Suzuki R, Kobayashi M, Itagaki S, Hirano T, Noda T, Mizuno S, Sugawara M, Iseki K.
  Involvement of cholesterol membrane transporter Niemann-Pick C1-like 1 in the intestinal absorption of lutein.
  J Pharm Pharm Sci. 2012;15(2):256-64
• Narumi K, Kobayashi M, Otake S, Furugen A, Takahashi N, Ogura J, Itagaki S, Hirano T, Yamaguchi H, Iseki K.
  Regulation of human monocarboxylate transporter 4 in skeletal muscle cells: the role of protein kinase C (PKC).
  Int J Pharm. 2012 May 30;428(1-2):25-32.
• Ogura J, Kuwayama K, Takaya A, Terada Y, Tsujimoto T, Koizumi T, Maruyama H, Fujikawa A, Takahashi N, Kobayashi M, Itagaki S, Hirano T, Yamaguchi H, Iseki K.
  Intestinal ischemia-reperfusion increases efflux for uric acid via paracellular route in the intestine, but decreases that via transcellular route mediated by BCRP.
  J Pharm Pharm Sci. 2012;15(2):295-304.
• Ogura J, Terada Y, Tsujimoto T, Koizumi T, Kuwayama K, Maruyama H, Fujikawa A, Takaya A, Kobayashi M, Itagaki S, Takahashi N, Hirano T, Yamaguchi H, Iseki K.
  The decrease in farnesoid X receptor, pregnane X receptor and constitutive androstane receptor in the liver after intestinal ischemia-reperfusion.
  J Pharm Pharm Sci. 2012;15(5):616-31.
• Segawa M, Ogura J, Seki S, Itagaki S, Takahashi N, Kobayashi M, Hirano T, Yamaguchi H, Iseki K.
  Rapid stimulating effect of the antiarrhythmic agent amiodarone on absorption of organic anion compounds.
  Drug Metab Pharmacokinet. 2013;28(3):178-86.
• Hamada Y, Shinohara Y, Yano M, Yamamoto M, Yoshio M, Satake K, Toda A, Hirai M, Usami M.
  Effect of the menstrual cycle on serum diamine oxidase levels in healthy women.
  Clin Biochem. 2013 Jan;46(1-2):99-10.

2011年度

• Kataoka Y, Mukohara T, Tomioka H, Funakoshi Y, Kiyota N, Fujiwara Y, Yashiro M, Hirakawa K, Hirai M, Minami H
  Foretinib (GSK1363089), a multi-kinase inhibitor of MET and EGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks.
  Invest New Drugs. 2011 Jun 8

• Kuwahara A, Yamamori M, Kadoyama K, Nishiguchi K, Nakamura T, Miki I, Tamura T, Okuno T, Omatsu H, Sakaeda T
  Effects of plasma concentrations of 5-fluorouracil on long-term survival after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.
  J Exp Clin Cancer Res. 2011 Oct 5;30:94.

• Aoganghua A, Nishiumi S, Kobayashi K, Nishida M, Kuramochi K, Tsubaki K, Hirai M, Tanaka S, Azuma T, Yoshida H, Mizushina Y, Yoshida M
  Inhibitory effects of vitamin K3 derivatives on DNA polymerase and inflammatory activity.
  Int J Mol Med. 2011 Dec;28(6):937-45

• Sato Y, Kobayashi M, Itagaki S, Hirano T, Noda T, Mizuno S, Sugawara M, Iseki K
  Pharmacokinetic properties of lutein emulsion after administration to rats and effect of food intake on plasma concentration of lutein.
  Biopharm. Drug Dispos. (32), 151-158, 2011.

• Sato Y, Kobayashi M, Itagaki S, Hirano T, Noda T, Mizuno S, Sugawara M, Iseki K
  Protective effect of lutein after ischemia-reperfusion in the small intestine,
  Food Chem. (127), 893-898, 2011.

• Sato Y, Itagaki S, Oikawa S, Ogura J, Kobayashi M, Hirano T, Sugawara M, Iseki K
  Protective effect of soy isoflavone genistein on ischemia-reperfusion in the rat small intestine,
  Biol. Pharm. Bull., 34(9), 1448-1454, 2011.

• Seki K, Senzaki K, Tsuduki Y, Ioroi T, Fujii M, Yamauchi H, Shiraishi Y, Nakata I, Nishiguchi K, Matsubayashi T, Takakubo Y, Okamura N, Yamamori M, Tamura T, Sakaeda T
  Risk factors for oxaliplatin-induced hypersensitivity reactions in Japanese patients with advanced colorectal cancer.
  Int J Med Sci. 8(3):210-205, 2011.

• Takara K, Matsubara M, Yamamoto K, Minegaki T, Takegami S, Takahashi S, Yokoyama T, Okumura K
  Differential effects of calcium antagonists on ABCG2/BCRP-mediated drug resistance and transport in SN-38-resistant HeLa cells.
  Molecular Medicine Reports. 5(3):603-609, 2012

• Takara K, Fujita M, Minegaki T, Yamamoto K, Takahashi M, Yokoyama T, Okumura K
  Treatment schedule-dependent effect of 5-fluorouracil and platinum derivatives in colorectal cancer cells.
  European Journal of Pharmaceutical Sciences. 45(3)272-281, 2012

• Nakamura A, Hara K, Yamamoto K, Yasuda H, Moriyama H, Hirai M, Nagata M, Yokono K
  Role of the mTOR complex 1 pathway in the in vivo maintenance of the intestinal mucosa by oral intake of amino acids.
  Geriatrics and Gerontology International. 12(1):131-139, 2012

• Takara K, Yamamoto K, Matsubara M, Minegaki T, Takahashi M, Yokoyama T, Okumura K
  Effects of α-Adrenoceptor Antagonists on ABCG2/BCRP-Mediated Resistance and Transport.
  PLoS One. 7(2):e30697

2010年度

• Yusoff S, Takeuchi A, Ashi C, Tsukada M, Maamor NH, Alwi Zilfalil B, Mohd Yusoff N, Nakamura T, Hirai M,
  Sari Kusuma Harahap I, Gunadi, Jin Lee M, Yutaka Takaoka NN, Morikawa S, Morioka I, Yokoyama N, Matsuo M,
  Nishio H, van Rostenberghe H
  A polymorphic mutation, c.-3279T>G, in the UGT1A1 promoter is a risk factor for neonatal jaundice in the Malay population.
  Pediatr Res. 67(4):401-406, (2010).

• Sato Y, Itagaki S, Kurokawa T, Ogura J, Kobayashi M, Hirano T, Sugawara M, Iseki K
  In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid.
  Int. J. Pharm., 403 (1-2), 136-138, (2010).

• Takegami S, Takara K, Tanaka S, Yamamoto K, Hori M, Yokoyama T, Kitade T
  Characterization, in vitro cytotoxicity and cellular accumulation of paclitaxel-loaded lipid nano-emulsions.
  Journal of Microencapsulation. 27(5):453-459, (2010).

• ST. Khan, H. Komaki, K. Motohashi, I. Kozone, A. Mukai, M. Takagi, K. Shin-ya K
  Streptomyces associated with a marine sponge Haliclona sp.; biosynthetic genes for secondary metabolites and products.
  Environ Microbiol. 13(2), 391-403, (2011).

• Kobayashi K, Nishiumi S, Nishida M, Hirai M, Azuma T, Yoshida H, Mizushina Y, Yoshida M
  Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNA polymerase inhibition and anti-inflammatory action.
  Med Chem. 7(1):37-44, (2011).

• JY. Ueda, M. Izumikawa, A. Mukai, A. Nagai, JH. Hwang, M. Takagi, K. Shin-Ya K
  New angucycline C-glycosides from Streptomyces sp. RI33. J Antibiot. 16, 367-372 (2011)

• 植田貴史，山森元博，小野由加里，田中健太，松本久美子，大松秀明，角本幹夫，槇本博雄，平野剛，平井みどり
  ACMIA 法で異常高値を示す症例の判別法の検討
  TDM 研究, 27(4), 168-172 (2010).

• 斎藤由起子，平野剛，沖洋充，笠師久美子，菅原満，小林正紀，高橋夏子，板垣史郎，井関健
  In vitro 実験系による肺がん化学療法レジメンの抗腫瘍効果の評価
  医療薬学, 36(4), 220-226 (2010).

• 板垣史郎，中田千絵，平野剛，鷹野瑠美，笠師久美子，菅原満，高橋夏子，小林正紀，井関健
  放射線治療に伴う口腔粘膜障害の予防・軽減効果が期待される物質の探索
  医療薬学, 36(9), 696-702 (2010).

• 林えり子，小林正紀，高橋夏子，平野剛，板垣史郎，山田武宏，井関健
  In vitro 実験系によるFOLFIRI 療法およびmFOLFOX6 療法レジメンの有効性およびEGFR 発現変動の評価
  医療薬学, 36(12), 855-862 (2010).