神戸大学大学院医学研究科　生理学・細胞生物学講座　生理学分野

研究業績

(2017年以降）

40.
Katagiri T, Nakamura S, Tachibana Y, Nakayama K, Mochizuki A, Dantsuji M, Baba K, Inoue T.
Tooth loss-associated neuroplasticity of mastication-related motor cortical neurons.   
J Oral Biosci (2025) online publication.

39.
Kaizuka T, Suzuki T, Kishi N, Tamada K, Kilimann MW, Ueyama T, Watanabe M, Shimogori T, Okano H, Dohmae N, Takumi T.   
Remodeling of the postsynaptic proteome in male mice and marmosets during synapse development.  
Nat Commun (2024) 15: 2496.

38.
Hagihara H, Shoji H, et al.   
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment.   
Elife (2024) 12: RP89376.

37.
Tsutsumi Y, Morita Y, Sato F, Furuta T, Uchino K, Sohn J, Haque T, Bae YC, Niwa H, Tachibana Y,
Yoshida A.   
Cerebellar nuclei receiving orofacial proprioceptive signals through the mossy fiber pathway from the supratrigeminal nucleus in rats.   
Cerebellum (2024) 23(5): 1795-1810.

36.
Tamada K, Takumi T.   
The East Asian-Specific Risk Genes in Autism Spectrum Disorder.   
Biol Psyhiatry (2023) 94: 762-764.

35.
Lin CW, Ellegood J, Tamada K, Miura I, Konda M, Takeshita K, Atarashi K, Lerch JP, Wakana S, McHugh TJ,
Takumi T.   
An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development.   
Mol Psychiatry (2023) 5: 1932-1945.

34.
Kato D, Aoyama Y, Nishida K, Takahashi Y, Sakamoto T, Takeda I, Tatematsu T, Go S, Saito Y, Kunishima S, Cheng J, Hou L, Tachibana Y, Sugio S, Kondo R, Eto F, Sato S, Moorhouse AJ, Yao I, Kadomatsu K, Setou M, Wake H.   
Regulation of lipid synthesis in myelin modulates neural activity and is required for motor learning.   
Glia (2023) 71(11): 2591-2608.

33.
Tsutsumi Y, Sato F, Furuta T, Uchino K, Moritani M, Bae YC, Kato T, Tachibana Y, Yoshida A.   
The cerebellar cortex receives orofacial proprioceptive signals from the supratrigeminal nucleus via the mossy fiber pathway in rats.   
Cerebellum (2023) 22(4): 663-679.

32.
Lin CW, Septyaningtrias DE, Chao HW, Konda M, Atarashi K, Takeshita K, Tamada K, Nomura J, Sasagawa Y, Tanaka K, Nikaido I, Honda K, McHugh TJ, Takumi T.   
A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model.   
Mol Psychiatry (2022) 8: 3343-3354.

31.
Narihara I, Yokoyama H, Namba H, Sotoyama H, Inaba H, Kitayama E, Tamada K, Takumi T, Nawa H. Increased self-triggered vocalizations in an epidermal growth factor-induced rat model for schizophrenia.
Sci Rep (2022) 12: 12917.

30.
Hasegawa Y, Sakuramoto A, Suzuki T, Sakagami J, Shiramizu M, Tachibana Y, Kishimoto H, Ono Y, Ono T.   
Emotional modulation of cortical activity during gum chewing: A functional near-infrared spectroscopy study.   
Front Neurosci (2022) 16: 964351.

29.
Yoshioka Y, Tachibana Y, Uesaka T, Hioki H, Fukumoto T, Enomoto H.   
Uts2b is a microbiota-regulated gene expressed in vagal afferent neurons connected to enteroendocrine cells producing cholecystokinin.   
Biochem Biophys Res Commun (2022) 608: 66-72.

28.
Hirata Y, Nomura K, Kato D, Tachibana Y, Niikura T, Uchiyama K, Hosooka T, Fukui T, Oe K, Kuroda R, Hara Y, Adachi T, Shibasai K, Wake H, Ogawa W.   
A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy.   
J Clin Invest (2022) 132(10): 1-13.

27.
Yoshida A, Inoue M, Sato F, Morita Y, Tsutsumi Y, Furuta T, Uchino K, Akhter F, Bae YC, Tachibana Y, Inoue T.   
Efferent and afferent connections of supratrigeminal neurons conveying orofacial muscle proprioception in rats.
Brain Struct Funct (2022) 227(1): 111-129.

26.
Tamada K, Fukumoto K, Toya T, Nakai N, Awasthi JR, Tanaka S, Okabe S, Spitz F, Saitow F, Suzuki H, Takumi T.   
Genetic dissection identifies Necdin as a driver gene in a mouse model of paternal 15q duplications.   
Nat Commun (2021) 12: 4056.

25.
Tsurugizawa T, Tamada K, Debacker C, Zalesky A, Takumi T.   
Cranioplastic Surgery and Acclimation Training for Awake Mouse fMRI.   
Bio Protoc (2021) 11: e3972.

24.
Awasthi JR, Tamada K, Overton ETN, Takumi T.   
Comprehensive topographical map of the serotonergic fibers in the male mouse brain.   
J Comp Neurol (2021) 529: 1391-1429.

23.
Tsutsumi Y, Mizuno Y, Haque T, Sato F, Furuta T, Oka A, Moritani M, Bae YC, Yamashiro T, Tachibana Y,
Yoshida A.
Widespread corticopetal projections from the oval paracentral nucleus of the intralaminar thalamic nuclei conveying orofacial proprioception in rats.   
Brain Struct Funct (2021) 226(4): 1115-1133.

22.
Okada T, Kato D, Nomura Y, Obata N, Quan X, Morinaga A, Yano H, Guo Z, Aoyama Y, Tachibana Y, Moorhouse AJ, Matoba O, Takiguchi T, Mizobuchi S, Wake H.   
Pain induces stable, active microcircuits in the somatosensory cortex that provide a new therapeutic target. Sci Adv (2021) 7(12): eabd8261.

21.
Awasthi JR, Tamada K, Overton ETN, Takumi T.   
Development of serotonergic projections to the suprachiasmatic nucleus in the mouse brain.   
Neurosci Lett (2020) 739: 135438-135438.

20.
Tsurugizawa T, Tamada K, Ono N, Karakawa S, Kodama Y, Debacker C, Kitamura A, Zalesky A, Takumi T. Awake functional MRI detects neural circuit dysfunction in a mouse model of autism.   
Sci Adv (2020) 6: eaav4520.

19.
Uemura Y, Haque T, Sato F, Tsutsumi Y, Ohara H, Oka A, Furuta T, Bae YC, Yamashiro T, Tachibana Y,
Yoshida A.  
Proprioceptive thalamus receiving forelimb and neck muscle spindle inputs via the external cuneate nucleus in the rat.   
Brain Struct Funct (2020) 225(7): 2177-2192.

18.
Sato F, Kado S, Tsutsumi Y, Tachibana Y, Ikenoue E, Furuta T, Uchino K, Bae YC, Uzawa N, Yoshida A.   
Ascending projection of jaw-closing muscle-proprioception to the intralaminar thalamic nuclei in rats.   
Brain Res (2020) 1739: 146830.

17.
Kato D, Wake H, Lee PR, Tachibana Y, Ono R, Sugio S, Tsuji Y, Tanaka YH, Tanaka YR, Masamizu Y, Hira R, Moorhouse AJ, Tamamaki N, Ikenaka K, Matsukawa N, Fields RD, Nabekura J, Matsuzaki M.   
Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity.   
Glia (2020) 68(1): 193-210.

16.
Septyaningtrias DE, Lin CW, Ouchida R, Nakai N, Suda W, Hattori M, Morita H, Honda K, Tamada K,
Takumi T.   
Altered microbiota composition reflects enhanced communication in 15q11-13 CNV mice.   
Neurosci Res (2019) 161: 59-67.

15.
Nishino T, Tamada K, Maeda A, Abe T, Kiyonari H, Funahashi Y, Kaibuchi K, Takumi T, Konishi H.   
Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain.   
Mol Brain (2019) 12: 94.

14.
Mori K, Tamada K, Kurooka H, Matsui M, Takumi T, Yokota Y.   
Gene expression profile data of the developing small intestine of Id2-deficient mice.   
Data in Brief (2019) 24: 103717.

13.
Furumai R, Tamada K, Liu X, Takumi T.   
UBE3A regulates the transcription of IRF, an anti-viral immunity.   
Hum Mol Genet (2019) 28: 1947-1958.

12.
Haruwaka K, Ikegami A, Tachibana Y, Ohno N, Konishi H, Hashimoto A, Matsumoto M, Kato D, Ono R, Kiyama H, Moorhouse AJ, Nabekura J, Wake H.   
Dual microglia effects on blood brain barrier permeability induced by systemic inflammation.   
Nat Commun (2019) 10(1): 5816.

11.
Murakami J, Tachibana Y, Akiyama S, Kato T, Taniguchi A, Nakajima Y, Shimoda M, Wake H, Kano Y, Takada M, Nambu A, Yoshida A.   
Oral splint ameliorates tic symptoms in patients with Tourette syndrome.   
Mov Disord (2019) 34(10): 1577-1578.

10.
Hikosaka O, Kim HF, Amita H, Yasuda M, Isoda M, Tachibana Y, Yoshida A.   
Direct and indirect pathways for choosing objects and actions.   
Eur J Neurosci (2019) 49(5): 637-645.

9.
Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y.   
Id2 determines intestinal identity through repression of the foregut transcription factor Irx5.   
Mol Cell Biol (2018) 38: e00250-17.

8.
Fukumoto K, Tamada K, Tsuyoshi Toya, Nishino T, Yanagawa Y, Takumi T.   
Identification of genes regulating GABAergic interneuron maturation.   
Neurosci Res (2018) 134: 18-29.

7.
Akiyoshi R, Wake H, Kato D, Horiuchi H, Ono R, Ikegami A, Haruwaka K, Omori T, Tachibana Y, Moorhouse AJ, Nabekura J.   
Microglia enhance synapse activity to promote local network synchronization.   
eNeuro (2018) 5(5): 0088-18.

6.
Tsutsumi Y, Tachibana Y, Sato F, Furuta T, Ohara H, Tomita A, Fujita M, Moritani M, Yoshida A.   
Cortical and subcortical projections from granular insular cortex receiving orofacial proprioception.   
Neurosci (2018) 388: 317-329.

5.
Ikenoue E, Akhter F, Tsutsumi Y, Sato F, Ohara H, Uchino K, Furuta T, Tachibana Y, Yoshida A.   
Transcortical descending pathways through granular insular cortex conveying orofacial proprioception.   
Brain Res (2018) 1687: 11-19.

4.
Nakai N, Nagano M, Saitow F, Yasuhito Watanabe, Kawamura Y, Kawamoto A, Tamada K, Mizuma H, Onoe H, Yasuyoshi Watanabe, Monai H, Hirase H, Nakatani J, Inagaki H, Kawada T, Miyazaki T, Watanabe M, Sato Y, Okabe S, Kitamura K, Kano M, Hashimoto K, Suzuki H, Takumi T.   
Serotonin Rebalances Cortical Tuning and Behavior Linked to Autism Symptoms in 15q11-13 CNV Mice.   
Sci Adv (2017) 3: e1603001.

3.
Kishimoto K, Nomura J, Ellegood J, Fukumoto K, Lerch JP, Moreno-De-Luca D, Bourgeron T, Tamada K,
Takumi T.   
Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication.   
Genes Cells (2017) 5: 436-451.

2.
Nishita M, Park S, Nishio T, Kamizaki K, Wang Z, Tamada K, Takumi T, Hashimoto R, Otani H, Pazour G, Hsu V, Minami Y.   
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness.   
Sci Rep (2017) 7: 1.

1.
Nakanishi M, Nomura J, Ji X, Tamada K, Arai T, Takahashi E, Bucan M, Takumi T.   
Functional significance of rare neuroligin1 variants found in autism.   
PLoS Genet (2017) 13: e1006940.

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