業績一覧


Rhamadianti AF, Abe T, Tanaka T, Ono C, Katayama T, Makino Y, Deng L, Matsui C, Moriishi K, Shima F, Matsuura Y and Shoji I. SARS-CoV-2 papain-like protease inhibits ISGylation of the viral nucleocapsid protein to evade host anti-viral immunity, Journal of Virology, 2024, in press.

Deng L, Solichin MR, Adyaksa DNM, Septianastiti MA, Fitri RA, Suwardan GNR, Matsui C, Abe T and Shoji I. Cellular release of infectious hepatitis C virus particles via endosomal pathways. Viruses, 2023,15, 2430.https://doi.org/10.3390/v15122430

Juniastuti, Utsumi T, Yamani LN, Dinana Z, Gunawan E, Maharani AT, Fitria AL, Wahyuni RM, Soetjipto, Doan YH, Shimizu H, Ishii K, Matsui C, Deng L, Abe T, Katayama K, Lusida MI, Shoji I. A household survey of intrafamily norovirus transmission, Journal of Medical Virology, 2023, Oct;95(10):e29164. doi: 10.1002/jmv.29164.

Ariffianto A, Deng L, Abe T, Matsui C, Ito M, Ryo A, Aly HH, Watashi K, Suzuki T, Mizokami M, Matsuura Y, and Shoji I. Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication. Journal of Virology, 2023, Oct 6:e0128723. doi: 10.1128/jvi.01287-23.

Ohta K, Ito K, Chida K, Nakashima K, Sakai S, Kanegae Y, Kawasaki H, Aoshima T, Takabayashi S, Takahashi H, Kawata K, Shoji I, Sawasaki T, Suda T, and Suzuki T. Role of hepcidin upregulation and proteolytic cleavage of ferroportin1 in hepatitis C virus-induced iron accumulation. PLOS Pathogens, 2023, Aug 16;19(8):e1011591. doi: 10.1371/journal.ppat.1011591. eCollection 2023 Aug.

Ariffianto A, Deng L, Harada S, Liang Y, Matsui C, Abe T and Shoji I. Transcription factor Jun B suppresses hepatitis C virus replication. Kobe Journal of Medical Sciences, 2023, 69(3): E86-E95.

Abe T, Marutani Y, Deng L, Matsui C, Fukasawa M, Suzuki R, Wakita T, Matsuura Y, Shoji I. Hepatitis C virus disrupts Annexin 5-mediated occludin integrity through downregulation of PKCα and PKC𝜂 expression, thereby promoting viral propagation. Journal of Virology, 2023, 97(6): e0065523. Doi:10.1128/jvi.00655-23.

Yamani LN, Utsumi T, Doan YH, Fujii Y, Dinana Z, Wahyuni RM, Gunawan E, Soegijanto S, Athiyyah AF, Sudarmo SM, Ranuh RG, Darma A, Soetjipto, Juniastuti, Bawono RG, Matsui C, Deng L, Abe T, Shimizu H, Ishii K, Katayama K, Lusida MI, Shoji I. Complete genome analyses of G12P[8] rotavirus strains from hospitalized children in Surabaya, Indonesia, 2017-2018. Journal of Medical Virology, 2023, 95: e28485, 1-11.

Yuliandari P, Matsui C, Deng L, Abe T, Mori H, Taguwa S, Ono C, Fukuhara T, Matsuura Y, and Shoji I. Hepatitis C virus NS5A protein promotes the lysosomal degradation of diacylglycerol O-acyltransferase 1 (DGAT1) via endosomal microautophagy. Autophagy Reports, 2022, 1, 264-285.

Gad SA, Sugiyama M, Tsuge M, Wakae K, FUkano K, Oshima M, Sureau C, Watanabe N, Kato T, Murayama A, Li Y, Shoji I, Shimotohno K, Chayama K, Muramatsu M, Wakita T, Nozaki T, Aly HH. The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro. PLoS Pathogens, 2022, 18: e1009983.

Deng L, Liang Y, Ariffianto A, Matsui C, Abe T, Muramatsu M, Wakita T, Maki M, Shibata H and Shoji I. Hepatitis C virus (HCV)-induced ROS/JNK signaling pathway activates the E3 ubiquitin ligase Itch to promote the release of HCV particles via polyubiquitylation of VPS4A. Journal of Virology, 2022,96: e0181121.

Matsui C, Yuliandari P, Deng L, Abe T and Shoji I. The role of chaperone-mediated autophagy in hepatitis C virus-induced pathogenesis. Frontiers in Cellular and Infection Microbiology, 2021, doi:10.3389/fcimb.2021.796664.

Bawono RG, Abe T, Qu M, Kuroki D, Deng L, Matsui C, Ryo A, Suzuki T, Matsuura Y, Sugiyama M, Mizokami M, Shimotohno K and Ikuo Shoji. HERC5 E3 ligase mediates ISGylation of hepatitis B virus X protein to promote viral replication. Journal of General Virology, 2021, 102(10). doi:10.1099/jgv.0.001668.

Bawono RG, Abe T, Shibata Y, Matsui C, Deng L and Shoji I. NS5A-ISGylation via Lysine 26 has a critical role for efficient propagation of hepatitis C virus genotype 2a. Kobe Journal of Medical Sciences, 2021, 67:E38-E47.

Utsumi T, Lusida MI, Dinana Z, Wahyuni RM, Soegijanto S, Soetjipto, Athiyyah AF, Sudarmo SM, Juniastuti, Yamani LN, Doan YH, Shimizu H, Ishii K, Matsui C, Deng L, Abe T, Katayama K and Shoji I. Molecular epidemiology and genetic diversity of Norovirus infection in children hospitalized with acute gastroenteritis in East Java, Indonesia during 2015-2019, Infection, Genetics and Evolution, 2021, 88: 104703, 1-10.

Wahyuni RM, Utsumi T, Dinana Z, Yamani LN, Juniastuti, Wuwuti IS, Fitriana E, Guwanan E, Liang Y, Ramadhan F, Soetjipto, Lusida MI and Shoji I. Prevalence and distribution of rotavirus genotypes among children with acute gastroenteritis in areas other than Java Island, Indonesia, 2016-2018. Frontiers in Microbiology, 2021, Article 672837.

Klionsky DJ, Shoji I et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 2021, 17, 1-382.

Abe T, Minami N, Bawono RG, Matsui C, Deng L, Fukuhara T, Matsuura Y and Shoji I. ISGylation of hepatitis C virus NS5A protein promotes viral RNA replication via the recruitment of cyclophilin A. Journal of Virology, 2020, 94:e00532-20.

Wulandari PS, Juniastuti, Wahyuni RM, Amin M, Yamani LN, Matondang MQY, Dinana Z, Soetjipto, Utsumi T, Shoji I and Lusida MI. Predominance of Norovirus GI.4 from children with acute gastroenteritis in Jambi, Indonesia, 2019. Journal of Medical Virology, 2020, 92:3165-3172.

Utsumi T, Wahyuni RM, Dinana Z, Gunawan E, Putra ASD, Mubawadi T, Soetjipto, Lusida MI and Shoji I. G2P[4] rotavirus outbreak in Belu, East Nusa Tenggara Province, Indonesia, 2018. Journal of Infection and Public Health, 2020, 13: 1592-1594.

Athiyyah AF, Utsumi T, Wahyuni RM, Dinana Z, Yamani LN, Soetjipto, Sudarmo SM, Ranuh RG, Darma A, Juniastuti, Raharjo D, Matsui C, Deng L, Abe T, Doan YH, Fujii Y, Shimizu H, Katayama K, Lusida MI and Shoji I. Molecular epidemiology and clinical features of rotavirus infection among pediatric patients in East Java, Indonesia during 2015-2018: dynamic changes in rotavirus genotypes from equine-like G3 to typical human G1/G3. Frontiers in Microbiology, 2019, 10:940.

Fujii Y, Doan YH, Wahyuni RM, Lusida MI, Utsumi T, Shoji I and Katayama K. Improvement of Rotavirus genotyping method by using the semi-nested multiplex-PCR with new primer set. Frontiers in Microbiology, 2019, 10:647.

Gunawan E, Utsumi T, Wahyuni RM, Dinana Z, Sudarmo SM, Shoji I, Soetjipto and Lusida MI. Post-vaccinated asymptomatic rotavirus infections: A community profile study of children in Surabaya, Indonesia. Journal of Infection and Public Health, 2019, 12:625-629.

Abe T, Marutani Y and Shoji I. Cytosolic DNA-sensing immune response and viral infection. Microbiology and Immunology, 2019, 63:51-64.

Deng L, Gan X, Ito M, Chen M, Aly HH, Matsui C, Abe T, Watashi K, Wakita T, Suzuki T, Okamoto T, Matsuura Y, Mizokami M, Shoji I and Hotta H. Peroxiredoxin 1, a novel HBx-interacting protein, interacts with Exosc5 and negatively regulates HBV propagation through degradation of HBV RNA. Journal of Virology, 2019, 93: e02203-18, 1-18.

Matsui C, Deng L, Minami N, Abe T, Koike K, and Shoji I. Hepatitis C virus NS5A protein promotes the lysosomal degradation of hepatocyte nuclear factor 1α via chaperone-mediated autophagy. Journal of Virology, 2018, 92: e000639-18, 1-14.

Utsumi T, Wahyuni RM, Doan YH, Dinana Z, Soegijanto S, Fujii Y, Juniastuti, Yamani LN, Matsui C, Deng L, Abe T, Soetjipto, Lusida MI, Ishii K, Shimizu H, Katayama K, and Shoji I. Equine-like G3 rotavirus strains as predominant strains among children in Indonesia in 2015-2016. Infection, Genetics and Evolution, 2018, 61: 224-228.

Utsumi T, Lusida MI, Dinana Z, Wahyuni RM, Yamani LN, Juniastuti, Soetjipto, Matsui C, Deng L, Abe T, Doan YH, Fujii Y, Kimura H, Katayama K, and Shoji I. Occurrence of norovirus infection in an asymptomatic population in Indonesia. Infection, Genetics and Evolution, 2017, 55, 1-7.

Minami N, Abe T, Deng L, Matsui C, Fukuhara T, Matsuura Y, and Shoji I. Unconjugated interferon-stimulated gene 15 specifically interacts with the hepatitis C virus NS5A protein via domain I. Microbiology and Immunology, 2017, 61 (7): 287-292.

Kawaguchi Y, Taoka M, Takekiyo T, Uekita T, Shoji I, Hachiya N, and Ichimura T. TRIM32-cytoplasmic-body formation is an ATP-requiring process stimulated by HSP70 ATPase function in cells. PLoS One, 2017, 12 (1): e0169436.

Aizawa S, Okamoto T, Sugiyama Y, Kouwaki T, Ito A, Suzuki T, Ono C, Fukuhara T, Yamamoto M, Okochi M, Hiraga N, Imamura M, Chayama K, Suzuki R, Shoji I, Moriishi K, Moriya K, Koike K, and Matsuura Y. TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis. Nature Communications, 2016, 7:11379.

Chen M, Gan X, Yoshino K, Kitagawa M, Shoji I, Deng L, and Hotta H. Hepatitis C virus NS5A protein interacts with lysine methyltransferase SET and MYND domain-containing 3 and induces activator protein 1 activation. Microbiology and Immunology, 2016, 60: 407-17.

Hayashi M, Deng L, Chen M, Gan X, Shinozaki K, Shoji I, and Hotta H. Interaction of the hepatitis B virus X protein with the lysine methyltransferase SET and MYND domain-containing 3 induces activator protein 1 activation. Microbiology and Immunology, 2016, 60: 17-25.

Deng L, Chen M, Shoji I, and Hotta H. HCV upregulates Bim through the ROS/JNK signaling pathway, leading to Bax-mediated apoptosis. Journal of General Virology, 2015, 96: 2670-83.

Sianipar IR, Matsui C, Minami N, Gan X, Deng L, Hotta H, and Shoji I. Physical and functional interaction between hepatitis C virus NS5A protein and ovarian tumor protein deubiquitinase 7B. Microbiology and Immunology., 2015, 59: 466-76.

Matsui C, Sianipar IR, Minami N, Deng L, Hotta H, and Shoji I. A single-amino-acid mutation in hepatitis C virus NS5A disrupts physical and functional interaction with the transcription factor HNF-1α. Journal of General Virology, 2015, 96: 2200-05.

Ratnoglik SL, Jang DP, Aoki C, Sudarmono P, Shoji I, Deng L, and Hotta H. Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities., PLoS One, 2014, 9 (6): e98877.

Ratnoglik, SL., Aoki, C., Sudarmono, P., Komoto, M., Deng, L., Shoji, I., Fuchino, H., Kawahara, N., and Hotta, H. Antiviral activity of extracts from Morinda citrifolia leaves and chlorophyll catabolites pheophorbide a and pyropheophorbide a, against hepatitis C virus. Microbiology and Immunology, 2014, 58 (3): 188-94.

Adianti, M., Aoki, C., Komoto, M., Deng, L., Shoji, I., Wahyuni, T., Lusida, M., Soetjipto, S., Fuchino, H., Kawahara, N., and Hotta, H. Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species. Microbiology and Immunology, 2014, 58 (3): 180-7.

Tao RR, Huang JY, Lu YM, Hong LJ, Wang H, Masood MA, Ye WF, Zhu DY, Huang Q, Fukunaga K, Lou YJ, Shoji I, Wilcox CS, Lai EY, Han F. Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo. Antioxidants & Redox Signaling, 2014, 21 (1): 1-16.

Mawatari, S., Uto, H., Ido, A., Nakashima, K., Suzuki, T., Kanmura, S., Kumagai, K., Oda, K., Tabu, K., Tamai, T., Moriuchi, A., Oketani, M., Shimada, Y., Sudoh, M., Shoji, I., and Tsubouchi, H. Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 4., PLoS One, 2013, 8 (12): e82094.

Wahyuni, TS., Tumewu, L., Permanasari, AA., Apriani, E., Adianti, M., Rahman, A., Widyawaruyanti, A., Lusida, MI., Fuad, A., Soetjipto, Nasronudin, Fuchino, H., Kawahara, N., Shoji, I., Deng, L., Aoki, C., and Hotta H. Antiviral activities of Indonesian medicinal plants in the East Java region against hepatitis C virus. VirologyJournal, 10 (1):259, 1-9, 2013.

Ichimura, T., Taoka, M., Shoji, I., Kato, H., Hatakeyama, S., Isobe, T., and Hachiya, N. 14-3-3 Proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitination and cytoplasmic body formation., Journal of Cell Science, 126 (Pt9): 2014-26, 2013.

El-Shamy, A., Shindo, M., Shoji, I., Deng, L., Okuno, T., and Hotta, H. Polymorphisms of the Core, NS3 and NS5A proteins of hepatitis C virus genotype 1b associate with development of hepatocellular carcinoma, Hepatology, 58 (2): 555-63, 2013.

El-Shamy, A., Shoji, I., El-Akel, W., Bilasy SE, Deng, L., El-Raziky, M., Jiang, D., Esmat, G., and Hotta, H. NS5A sequence heterogeneity of hepatitis C virus genotype 4a predicts clinical outcome of pegylated-interferon/ribavirin therapy in Egyptian patients., J Clinical Microbiology, 50 (12): 3886-92, 2012.

Matsui, C., Shoji, I., Kaneda, S., Sianipar, IR., Deng, L., and Hotta, H. Hepatitits C virus infection suppresses GLUT2 gene expression via down-regulation of hepatocyte nuclear factor 1α. Journal of Virology, 86 (23): 12903-11, 2012.

Nakashima, K., Takeuchi, K., Chihara, K., Deng, L., Shoji, I., Hotta, H., and Sada, K. HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinases Fyn in B cells., PLoS One, 7 (10):e46634, 2012.

Kim, S-R., El-Shamy, A., Imoto, S., Kim, KI., Ide, Y-H., Deng, L., Shoji, I., Tanaka, Y., Hasegawa, Y., Ota, Mitsuhiro., and Hotta, H. Prediction of response to pegylated inferferon/ribavirin combination therapy for chronic hepatitis C genotype 1b and high viral load., Journal of Gastroenterology, 47 (10): 1143-51, 2012.

El-Shamy, A., Shoji, I., Kim S-R., Ide, Y-H., Imoto, S., Deng, L., Yoon, S., Fujisawa, T., Tani, S., Yano, Y., Seo, Y., Azuma, T., and Hotta, H. Sequence heterogeneity in NS5A of hepatitis C virus gentypes 2a and 2b and clinical outcome of pegylated-Interferon/Ribavirin therapy., PLoS One, 7, e30513, 1-10, 2012.

Sasayama, M., Shoji, I., Adianti M, Jiang DP, Deng, L, Saito T, Watanabe H, Kawata S, Aoki C, and Hotta, H. A point mutation at Asn-534 that disrupts a conserved N-glycosylation motif of the E2 glycoprotein of hepatitis C virus markedly enhances the sensitivity to antibody neutralization. Journal of Medical Virology, 84, 229-34, 2012.

Kamada, K., Shoji, I., Deng, L, Wakita, T., and Hotta, H. Generation of a recombinant reporter hepatitis C virus useful for the analyses of virus entry, intra-cellular replication and virion production. Microbes and Infection, 14, 69-78, 2012.

El-Shamy, A., Ide, Y-H., Kim, SR., Sasase, N., Imoto, S., Deng, L., Shoji, I., and Hotta, H. Polymorphisms of hepatitis C virus NS5A and core proteins and clinical outcome of pegylated interferon/ribavirin therapy. Intervirology, 55, 1-11, 2012.

Deng, L., Shoji, I., Oawa, W., Kaneda, S., Soga, T., Jiang, D. P., Ide, Y-H., and Hotta, H., Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway. Journal of Virology, 85, 8556-68, 2011.

Yamagishi, Y., Shoji, I., Miyagawa, S., Kawakami, T., Katoh, T., Goto, Y., and Suga, H. Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library. Chemistry & Biology, 18, 1562-1570, 2011.

El-Shamy, A., Shoji, I., Saito, T., Watanabe H., Ide, Y-H., Deng, L., Kawata, S., and Hotta, H. Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to Pegylated-Interferon/Ribavirin combination therapy. Microbiology and Immunology, 55, 418-26, 2011.

Inoue, Y., Aizaki, H., Hara, H., Matsuda, M., Ando, T., Shimoji, T., Murakami, K., Masaki, T., Shoji, I., Homma, S., Matsuura, Y., Miyamura, T., Lai, MMC, Wakita, T., and Suzuki, T. Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein. Virology, 410, 38-47, 2011.

Hayashida K, Shoji, I., Deng, L., Ide, Y-H., and Hotta, H. 17-Estradiol inhibits the production of infectious particles of hepatitis C virus. Microbiology and Immunology, 54, 684-90, 2010.

Kim SR., Imoto S., Kudo M., Nakajima T., Ando K., Mita K., Fukuda K., Hong HS., Lee YH., Nakashima K., Shoji I., Nagano-Fujii M., Hotta H., and Hayashi Y. Autoimmune thrombocytopenic purpura during pegylated Interferon α treatment for chronic hepatitis C. Internal Medicine, 49, 1119-1122, 2010.

Nasu, J., Murakami, K., Miyagawa, S., Yamashita, R., Ichimura, T., Wakita, T., Hotta, H., Miyamura, T., Suzuki, T., Satoh, T., and Shoji, I. E6AP ubiquitin ligase mediates ubiquitin-dependent degradation of peroxiredoxin 1. Journal of Cellular Biochemistry, 111, 676-85, 2010.

Moriishi K., Shoji, I., Mori, Y., Suzuki, R., Suzuki, T., Kataoka, C., and Matsuura, Y. Involvement of PA28γ in the propagation of hepatitis C virus. Hepatology, 52 411-420 2010.

Sanjo M., Saito, T., Ishii, R., Nishise, Y., Haga, H., Okumoto, K., Ito, J., Watanabe, H., Saito, K., Togashi, H., Fukuda, K., Imai, Y., El-Shamy, A., Deng, L., Shoji, I., Hak, H., and Kawata, S. Secondary structure of the amino-terminal region of HCV NS3 and virological response to pegylated interferon plus ribavirin therapy for chronic hepatitis C. Journal of Medical Virology, 82, 1364-70, 2010.

Sasayama, M., Deng, L., Kim, SR., Ide Y-H., Shoji, I., and Hotta, H. Analysis of neutralizing antibodies against hepatitis C virus in patients who were treated with peglated-Interferon plus ribavirin. Kobe Journal of Medical Sciences, 56, E60-E66, 2010.

Kim, SR., Imoto, S., Kudo, M., Mita, K., Taniguchi, M., Kim, KI., Sasase, N., Shoji, I., Nagano, M., El-Shamy, A., Hotta, H., Nagai, T., Nagata, Y., and Hayashi, Y. Double filtration plasmapheresis plus interferon treatment for non-sustained virological response to previous combination therapy: Early viral dynamics. Intervirology, 53, 44-48, 2010.

Sasase, N., Kim, SR., Kudo, M., Kim, KI., Taniguchi, M., Imoto, S., Mita, K., Hayashi, Y., Shoji, I., El-Shamy, A., and Hotta, H. Outcome and early viral dynamics with viral mutation in PEG-IFN/RBV combination therapy for chronic hepatitis in patients with high viral loads of serum HCV RNA genotype 1b. Intervirology, 53, 49-54, 2010.

An, C., Ide Y., Nagano-Fujii, M., Kitazawa, S., Shoji, I., and Hotta, H. A transgenic mouse line with a 58-kb fragment deletion in chromosome 11E1 that encompasses part of the Fam20a gene and its upstream region shows growth disorder. Kobe Journal of Medical Sciences, 55, 82-92, 2010.

Bungyoku, Y., Shoji, I., Makine, T., Adachi, T., Hayashida, K., Nagano-Fujii, M., Ide Y., Deng, L., and Hotta, H. Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells. Journal of General Virology, 90, 1681-91, 2009.

Hara, H., Aizaki, H., Matsuda, M., Shinkai-Ouchi, F., Inoue, Y., Murakami, K., Shoji, I., Kawakami, H., Matsuura, Y., Lai, MMC., Miyamura, T., Wakita, T., and Suzuki, T. Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein. Journal of Virology, 83, 5137-47, 2009.

Jian, D.P., Ide, Y., Nagano-Fujii, M., Shoji, I., and Hotta, H. Single-point mutations of the M protein of a measles virus variant obtained from a patient with subacute sclerosing panencephalitis critically affect solubility and subcellular localization of the M protein and cell-free virus production. Microbes and Infection, 11, 467-75, 2009.

Shimoji, T., Murakami, K., Sugiyama, Y., Matsuda, M., Inubushi, S., Nasu, J., Shirakura, M., Suzuki, T., Wakita, T., Kishino, T., Hotta, H., Miyamura, T., and Shoji, I., Identification of annexin A1 as a novel substrate for E6AP-mediated ubiquitylation. Journal of Cellular Biochemistry, 106, 1123-1135, 2009.

Kasai, D., Adachi, T., Lin, D., Nagano-Fujii, M., Sada, K., Ikeda, M., Kato, N., Ide, Y., Shoji, I., and Hotta, H. HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters.Journal ofHepatology, 50, 883-94, 2009.

Suzuki, R., Moriishi, K., Fukuda, K., Shirakura, M., Ishii, K., Shoji, I., Wakita, T., Miyamura, T., Matsuura, Y., and Suzuki, T. Proteasomal turnover of hepatitis C virus core protein is regulated by dual mechanisms, ubiquitin-dependent and ubiquitin-independent but PA28g-dependent. Journal of Virology, 83, 2389-2392, 2009.

Deng, L., Adachi, T., Kitayama, K., Bungyoku, Y., Kitazawa, S., Ishido, S., Shoji, I., and Hotta, H. Hepatitis C virus infection induces apoptosis through a Bax-triggered, mitochondria-mediated, Caspase-3-dependent pathway. Journal of Virology, 82, 10375-85, 2008.

Sasase, N., Kim, S.R., Kim, K.I., Taniguchi, M., Imoto, S., Mita, K., Hotta, H., Shoji, I., El-Shamy, A., Kawada, N., Kudo, M., and Hayashi, Y. Usefulness of a new immunoradiometric assay of HCV core antigen to predict virological response during PEG-IFN/RBV combination therapy for chronic hepatitis with high viral load of serum HCV RNA genotype 1b. Intervirology, 51, 70-5, 2008.

Murakami, K., Kimura, T., Osaki, M., Ishii, K., Miyamura, T., Suzuki, T., Wakita, T., and Shoji, I. Virological characterization of the HCV JFH-1 strain in lymphocytic cell lines. Journal of General Virology, 89, 1587-92, 2008.

Murakami, K., Inoue, Y., Hmwe, S.S., Omata, K., Hongo, T., Ishii, K., Yoshizaki, S., Aizaki, H., Matsuura, T., Shoji, I., Miyamura, T., and Suzuki, T. Dynamic behavior of hepatitis C virus quasispecies in a long-term culture of the three-dimensional radial-flow bioreactor system. Journal of Virological Methods, 148, 174-181, 2008.

Shirakura, M., Murakami, K., Ichimura, T., Suzuki, R., Shimoji, T., Fukuda, K., Abe, K., Sato, S., Fukasawa, M., Yamakawa, Y., Nishijima, M., Moriishi, K., Matsuura, Y., Wakita, T., Suzuki, T., Howley, P.M., Miyamura, T, and Shoji, I. E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein. Journal of Virology, 81, 1174-1185, 2007.

Sato, S., Fukasawa, M., Yamakawa, Y., Natsume, T., Suzuki, T., Shoji, I., Aizaki, H., Miyamura, T., and Nishijima, M. Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein. Journal of Biochemistry, 139, 921-30, 2006.

Murakami, K., Ishii, K., Ishihara, Y., Yoshizaki, S., Tanaka, K., Gotoh, Y., Aizaki, H., Kohara, M., Yoshioka, H., Mori, Y., Manabe, N., Shoji, I., Sata, T., Bartenschlager, R., Matsuura, Y., Miyamura, T., and Suzuki, T. Production of infectious hepatitis C virus particles in three-dimensional cultures of the cell line carrying the genome-length dicistronic viral RNA of genotype 1b. Virology, 351, 381-92, 2006.