CMX

New Members in FY 2024

Hideaki MIYAKE

Professor, Div. of Urology, Dept. of Surgery Related

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In December, 2023, I was appointed as Professor in Division of Urology, and it is a great pleasure for me to join the CMX as one of the members in the field of drug discovery and medical device development. I had been involved in the development of a novel anticancer agent, which was evaluated in the phase 3 clinical trials. In addition, our division has played the central role in the development of the surgical robot, hinotori, and we have recently tried to establish the system of telesurgery using hinotori. I would like to contribute the activity of CMX as much as possible by utilizing such my previous experiences.

Yoshihiro MURAGAKI

Professor, Div. of Precision Theranostic Devices, Dept. of Medical Device Engineering

In April 2023, I was honored to take on the role of professor at the newly established Department of Medical Device Engineering. My mission is to nurture innovative professionals who can tackle complex challenges and contribute to commercialization of domestically-produced medical devices. My research encompasses a range of components, therapeutic devices, and program-based medical devices. In the field of neurology, I have developed devices such as EEG recording systems and laser-holding devices for treating malignant brain tumors.

As a researcher and physician, my specialization aligns with Professor Takashi Sasayama in neurosurgery, focusing on malignant brain tumors. During my overseas studies, I explored differentiation induction therapy for pediatric brain tumors through the genetic introduction of neurotrophic factor receptors. Clinically, I have identified the brain's "grammar center" using functional MRI, conducted brain function mapping through awake surgery, and pursued clinical research on cortico-cortical evoked potentials. Currently, I am leading physician-directed clinical trials on autologous tumor vaccines.

Joining CMX is an exciting opportunity, and I am enthusiastic about collaborating with all of you on development research to translate discoveries and methodologies from human brain function studies and fundamental research into practical medical devices. I sincerely appreciate your support as we embark on this journey together.

Youichi KUREBAYASHI

Project Professor, Div. of AI and Digital Health Sciences, Dept. of Social/Community Medicine and Health Science

I serve as Professor in the Department of AI and Digital Health Science. At our laboratory, we conduct data-driven research by integrating medical big data with artificial intelligence, working closely with a diverse range of stakeholders—including national and local governments, as well as pharmaceutical, medical device, and IT companies.

Our mission is to tackle real-world healthcare challenges such as predicting disease progression, supporting diagnostics, and improving the quality of care. We also strive to translate our research outcomes into real-world applications to drive continuous innovation in the medical field. Through our participation in CMX, we aim to further advance the integration of medicine and information science by leveraging our experience and infrastructure in big data analytics. We appreciate your continued interest and support.

Yoshiaki TADOKORO

CMX Project Assistant Professor, Div. of Immunology, Dept. of Future Medical Sciences

Since April 2024, I have been serving in my current position. Until now, my research has focused on the development of novel therapeutic strategies for oral cancer and prognostic prediction in oral infectious diseases. Currently, I am engaged in basic research inspired by questions that arise in clinical practice, with the aim of elucidating the mechanisms underlying the onset and progression of various disease states. In particular, I am investigating the dynamics of immune cells in age-related diseases to contribute to the development of optimal treatment approaches.

Moving forward, I hope to collaborate with researchers and clinicians across both basic and clinical fields to gain multifaceted insights into how localized diseases affect systemic health and to further explore organ-specific pathological responses. I sincerely appreciate your continued guidance and support.

Yuta YAMAGUCHI

CMX Project Assistant Professor, Div. of Pharmacology, Dept. of Biochemistry and Molecular Biology

I was appointed as a Project Assistant Professor in the Department of Pharmacology in April 2023. My previous research focused on the innate immune system, particularly its crucial role in frontline defense against infections and inflammatory conditions.

Building upon this experience, I am currently investigating how immune responses and inflammatory processes triggered by psychological and physiological stress contribute to the pathology of psychiatric and neurological disorders, such as depression and anxiety, aiming to uncover disease mechanisms and develop innovative therapeutic strategies. Furthermore, since April 2024, I have been a member of the Center for Medical Transformation (CMX), actively engaging in cross-disciplinary and translational research integrating immunology and neuroscience. Through my ongoing research, I hope to establish more effective treatment approaches and improve patients’ quality of life. I greatly appreciate your continued guidance and support.