CMX Young Scientists Collaborative Research Project Special Lecture
Introduction to In Vivo Tissue Immunology: Elucidating the Spatiotemporal Diversity of Immune Responses
Masaru Ishii
Dean and Professor of Immunology and Cell Biology, Graduate School of Medicine, The University of Osaka
| （DATE & TIME） Monday, Jul. 2025 (Reiwa 7), from １６：４０ to １８：２０ |
| （Location） ・In-person: Sysmex Hall ・Web: Participants will be provided with a URL separately upon registration. |
| （Allication Method） Please refer to the notifications for each lab. |
| Abrsract For us "animals," movement is essential. Within our bodies, the movements of various types of cells are precisely controlled in both space and time. Traditional analytical methods, which involve isolating cells or tissues from animals, are inadequate for studying such systems. While fixed and sectioned tissue samples allow us to analyze cellular morphology and molecular expression, they cannot capture cellular movement. To observe cell dynamics, we must visualize living cells within living tissues and living organisms. In this lecture, I will present the in vivo imaging studies I have conducted across various tissues, as well as the biochemical analyses of tissues based on these visualized data. I will showcase the sophisticated movements of cells that were revealed only through direct observation and introduce newly identified cell types that could only be discovered by observing living organisms. In particular, I will discuss in detail the immunosuppressive mechanism recently discovered in the liver and its pathophysiological significance, including the process and context that led to its identification. |