CMX Young Scientists Collaborative Research Project in FY 2025：Selected Topics Announced

CMX invited applications for the FY 2025 Young Researchers Joint Project (application period: May 8, 2025– June 23, 2025), and after a rigorous review process by the Center’s Advisory Board and Steering Committee, the following topics have been selected.

type A:Xenium	Title:Elucidation of the pathogenic mechanism of mitochondrial palmoplantar keratoderma complicated with deafness PI:Natsumi Uehara (Div. of Otolaryngology-Head and Neck Surgery) Co-I:Ai Yoshioka (Div. of Dermatology)
type A:Xenium	Title:Spatial Transcriptomics and Single-Cell Repertoire Profiling Reveal the Pathogenesis of IgG4-Related Aortic Aneurysms and Gastrointestinal Diseases PI:Takuo Emoto (Div. of Cardiovascular Medicine) Co-I:Takanori Matsuura (Div. of Gastroenterology)
type A:Xenium	Title:Elucidating the roles of brain-resident T cells in the very early stages of Alzheimer's disease PI:Asato Tsuji (Div. of Neurology) Co-I:Yoshiaki Tadokoro (Div. of Immunology)
type A:Mantra2	Title:Uncovering the spatial basis of glioblastoma progression driven by a necrosis-triggered stemness–lipid metabolism network PI:Hiroaki Nagashima (Div. of Neurosurgery) Co-I:Jiang Guanhua (Div. of Cell Physiology)
type C:International	Title:Whole-brain profiling of altered sensory responses to social cues in autism spectrum disorder model mice PI:Nobuhiro Nakai（Biological Psychiatry, Div. of Psychiatry） Co-I:Kentaro Ishii (Stuber Lab. Univ. of Washington)
Application	Number of Applications: 9 Number of Winners: 5

Application guidelines for FY2025

Aim of the Grand	The grant seeks to advance joint and international collaborative research among young researchers, aligning with the mission of the Center for Medical Transformation (CMX) . It aims to support developmental research that contributes to the Center’s future.
Types of Research Funded	Collaborative research among CMX young researchers or between CMX and the Graduate School researchers (outside CMX). One may be a researcher in our Graduate School (outside of our Center), but we prefer young researchers who can conduct developmental research that can play a role in the future of our Center. Encouraged: Interdisciplinary projects like combining "intractable cancer" and "drug discovery and medical devices". Required Equipment Use: Proposals must utilize one or more of the following: ・Xenium: Contact Professor Masashi Horie ・Mantra2: Contact Associate Professor Yuichiro Koma ・Electron Microscope: Contact Professor Ryo Nitta Collaborative proposals must be consulted with the respective faculty by June 9, 2025,* two weeks prior to the application deadline.* Note: While multiple applications from the same labs are acceptable, adjustments may be made at the review stage when two or more applications are submitted. Joint research projects between CMX young researcher and those in other university departments . International joint research projects between CMX young researchers in CMX and those in overseas research institutes.
Applicant Eligibility	Young researchers (excluding graduate students) under 44 years old (or under 46 for those graduated from a sixth-year universities) OR less than 10 years post-doctorate. Preference: Principal or co-investigator under 40 years old.
Expenses to be covered by the grant	Expenses necessary for the joint research (in principle, excluding equipment and fixtures) Only direct expenses are eligible, and indirect expenses are not included.
Grant	About 3-4 projects will be adopted in types A to C. One fiscal year budget of 1.5 to 2 million yen (750,000 to 1 million yen per researcher) *Equally distributed among Principal Investigators/Co-investigators One fiscal year budget of 500,000-2,000,000 yen (allocated only to young researchers within the Center) One fiscal year budget of 1 to 2 million yen (allocated only to young researchers in the Center) type A: When applying as a continuation or development of a research proposal adopted in the previous year by the same joint research organization, the maximum amount is 3,000,000 yen. The principal investigators and co-investigators shall be equally responsible for the proper use of the budget.
Deadline for application	Noon, Monday, June 23, 2025 Applications are now closed.
How to apply	E-mail applications to the address below: k9shien＊med.kobe-u.ac.jp (change ＊ to @) Subject : Application for 2025 CMX Young Scientists Collaborative Research Project
Schedule	May. 9 to Noon, Jun. 23：Application period by Aug. 8：Announcement of results about mid Aug：Allocation of research fund
Application Guideline・Application Form	Guideline