CMX

CMX WORKSHOP Emergence Conference in FY2024

DATE Mon, Nov. 18, 2024 TIME 13:00
VENUE Shinryoku Memorial Hall

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The 4th Emergence Conference was held on January 18, 2024 at Kobe University Shinryokaikan Memorial Hall.
The aim of this conference is to "invite leading Japanese researchers to present their highly original research, to learn about cutting-edge research trends, to gain new perspectives including clinical applications, and to provide an opportunity for new collaboration". This year's theme is "Organoid Medicine", which is the hottest topic in the field of regenerative medicine.

“Organoids” are defined as "cell-based, three-dimensional in vitro models of complex structural and functional aspects of organs in vivo, which contribute to research on development, disease modeling, drug discovery, diagnosis, and personalized medicine. The development, modification, and optimization of new protocols are still being fought over on a global level.

In the conference, Dr. Jun Nomura, Department of Physiology, Faculty of Medicine, who served as the organizer of this conference, gave a lecture on research trends on organoids. Dr. Ryuhei Hayashi, Osaka University School of Medicine, gave a lecture on "Development of regenerative eye treatment using pluripotent stem cell-derived organoids", and Dr. Michiyo Koyanagi-Aoi, Kobe University School of Medicine, gave a lecture on "Elucidation of human development and pathological mechanisms using organoids and their therapeutic applications". Next, Dr. Hideya Sakaguchi of the RIKEN BDR-OTSUKA Collaboration Center gave a lecture on "Evaluation of human neural activity at the circuit level enabled by neural organoids and its prospects for organoid medicine," and Dr. Katsuhiko Hayashi of Osaka University School of Medicine gave a lecture on "Reconstruction and manipulation of germline and sex differentiation processes. Dr. Toshiro Sato of Keio University School of Medicine gave a special lecture on "Understanding digestive cancers by organoids". Especially, Dr. Katsuhiko Hayashi of Osaka University was selected as one of the "10 people who contributed to science in 2023" by the "Nature".

The conference successfully fulfilled its objectives this year as well, thanks to the active exchange of questions and opinions among the speakers and participants. I would like to express my sincere gratitude to all the people involved.

(Jun Nomura, Kobe University School of Medicine)

PROGRAM

13:00

Opening Remarks

Akira Suzuki
Vice Director of CMX
Division of Molecular and Cellular Biology, Graduate School of Medicine, Kobe University

13:05 Mini-Lecture

Challenges of Organoid Research -Basics and Trends in Organoid Research

Jun Nomura
Division of Physiology, Department of Physiology and Cell biology, Graduate School of Medicine, Kobe University

13:15 Lecture 1

Establishment of patient-derived organoids from early pancreatic cancer

Yuzo Kodama
Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine

13:45 Lecture 2

Development of regenerative therapy for the eye using pluripotent stem cell-derived organoids.

Ryuhei Hayashi Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine

14:25 Lecture 3

Using organoids to elucidate the mechanisms of human development and diseases and apply them to treatment

Michiyo Koyanagi-Aoi
Division of Sem Cell Medicine, Department of Future Medical Science, Kobe University Graduate School of Medicine

14:55

BREAK

15:20 Lecture 4

Network-level analysis of human neural function using neural organoids and the future perspective of neural organoid technology as organoid medicine

Hideya Sakaguchi
Neural Organogenesis Laboratory, BDR-Otsuka Pharmaceutical Collaboration Center, RIKEN Center for Biosystems Dynamics Research

16:00 Lecture 5

Reconstitution and control of germ cell development and sex determination.

Katsuhiko Hanashi
Department of Genome Biology, Osaka University Graduate School

16:40

BREAK

17:00 Keynote Lecture

Understanding Gastrointestinal Cancers using Organoid Technology

Toshiro Sato
Department of Organoid Medicine, Keio University School of Medicine

18:00

Closing Remarks

Toru Takumi
Director of CMX
Division of Physiology, Graduate school of Medicine