{
  "generated": "2026-10-16",
  "schema_version": "1.0",
  "name": "Department of Neurophysiology",
  "name_ja": "神経生理学分野",
  "parent_organization": "Kobe University Graduate School of Medicine",
  "parent_organization_ja": "神戸大学大学院医学系研究科",
  "url": "https://www.med.kobe-u.ac.jp/neurophy/",
  "url_ja": "https://www.med.kobe-u.ac.jp/neurophy/ja/",
  "established": "January 2026",
  "tagline": "Sleep is the operating system of memory and emotion.",
  "overview": "The Department of Neurophysiology at Kobe University Graduate School of Medicine investigates how the sleeping brain consolidates memory. The laboratory dissects the REM-sleep circuits that integrate adult-born neurons into memory traces, develops tools that decode sleep stages in real time, explores memory reactivation through sound during sleep, and translates these findings toward clinical applications, with a focus on PTSD. It collaborates with NCNP, IIIS Tsukuba, RIKEN CBS, and partners across Japan, North America, and Asia.",
  "central_question": "How does the sleeping brain consolidate memory?",
  "pillars": [
    {
      "id": "pillar1",
      "name": "Sleep-driven dynamics of memory",
      "name_ja": "睡眠による記憶ダイナミクスの基礎機序",
      "description": "Basic mechanisms of how sleep, particularly REM sleep, supports memory consolidation and the circuit-level integration of newly generated neurons; memory remapping, metabolism and circuit dynamics during sleep; and analysis tools that follow the same neurons over long periods.",
      "themes": [
        "adult_neurogenesis_memory",
        "rem_sleep_memory",
        "sleep_circuits",
        "imaging_tools",
        "sleep_staging_closed_loop_tools"
      ],
      "description_ja": "睡眠 — とりわけレム睡眠 — が、記憶の固定や、新たに生まれたニューロンの回路レベルでの統合をどのように支えるのか。その基本機構を解明します。"
    },
    {
      "id": "pillar2",
      "name": "Sleep and PTSD — pathophysiology and therapeutic technology development",
      "name_ja": "睡眠とPTSD — 病態メカニズムと治療技術開発",
      "description": "Animal studies of trauma-related fear memory paired with clinical studies of sleep in people with PTSD, and development of Sound Exposure during Sleep (SES), an investigational platform that delivers individualized auditory cues during specific sleep stages. SES is at an exploratory stage; it is not an established treatment.",
      "themes": [
        "fear_memory_ptsd",
        "sound_exposure_during_sleep",
        "human_sleep_clinical"
      ],
      "description_ja": "動物モデルでのトラウマ関連恐怖記憶の研究と、PTSD 患者を対象とした臨床研究を組み合わせ、睡眠中音刺激 Sound Exposure during Sleep（SES）の開発につなげます。SES は探索段階の研究で、確立した治療ではありません。"
    },
    {
      "id": "pillar3",
      "name": "Sleep-Enabled Neural Regenerative Medicine",
      "name_ja": "睡眠を利用した神経再生医療",
      "description": "A lineage that runs from the discovery of Galectin-1 as a driver of adult neurogenesis, through causal studies of adult-born neurons in memory, toward approaches in which sleep helps newly added neurons join host circuits.",
      "themes": [
        "neural_stem_cells_galectin",
        "neural_regeneration_transplantation",
        "adult_neurogenesis_memory"
      ],
      "description_ja": "Galectin-1 を成体神経新生の駆動因子として同定した発見から、成体新生ニューロンと記憶の因果研究を経て、睡眠を新たな細胞が回路と出会う環境として活用する再生医療へ向かう系譜です。"
    }
  ],
  "ses": {
    "name": "Sound Exposure during Sleep (SES)",
    "status": "Investigational platform at an exploratory stage. It is not an established treatment. No medical advice is given and no participants are being recruited.",
    "first_in_human_study": {
      "registry_id": "jRCT1030230706",
      "registry_url": "https://jrct.mhlw.go.jp/en-latest-detail/jRCT1030230706",
      "design": "Medical-institution-led, first-in-human feasibility study",
      "status": "Completed; the study period has ended and no participants are being recruited.",
      "consented": 13,
      "completed_overnight_ses": 6,
      "tolerability": "The intervention was well tolerated, and no adverse events were attributed to the auditory cues.",
      "preprint_url": "https://medrxiv.org/cgi/content/short/2026.05.02.26352243v1"
    }
  },
  "pi": {
    "name": "Masanori Sakaguchi",
    "name_ja": "坂口 昌徳",
    "degrees": "MD, PhD",
    "title": "Professor and Chair, Department of Neurophysiology, Kobe University Graduate School of Medicine",
    "biography": "Masanori Sakaguchi received his medical degree from the University of Tsukuba in 2001 and completed his PhD in Medicine at the Graduate School of Comprehensive Human Sciences, University of Tsukuba, in 2005. He then served as a research associate in the Department of Physiology at Keio University School of Medicine (2005–2007), followed by a postdoctoral fellowship in Paul Frankland's laboratory at the Hospital for Sick Children Research Institute (SickKids), Toronto (2007–2009). From 2013 to 2025, he was Associate Professor at the International Institute for Integrative Sleep Medicine (IIIS), University of Tsukuba — initially co-leading a research group with Professor Takeshi Sakurai (2013–2018), and from October 2018 leading his own laboratory. From 2022 he held a tenured Associate Professorship in the Faculty of Medicine, University of Tsukuba. In January 2026 he was appointed Professor and Chair of the Department of Neurophysiology at Kobe University Graduate School of Medicine. Since May 2026 he has also held a Visiting Professorship at the University of Tsukuba, and he concurrently holds a visiting researcher position at the RIKEN Center for Brain Science (CBS).",
    "selected_funding": "JSPS Kiban-A (PI 2026–), Grant-in-Aid for Transformative Research Areas (B) (PI 2024–2026), AMED translational research grants, AMED Translational Research Program Seeds S1 (PI 2026–), Moonshot R&D Goal 7 (Co-PI), JST CREST (Co-PI 2026–).",
    "email_display": "masakagu [at] med.kobe-u.ac.jp",
    "identifiers": {
      "orcid": "0000-0002-7211-9452",
      "kaken_researcher_number": "60407088",
      "researcher_id": "AFL-2000-2022",
      "j_global_id": "201201028969040510"
    },
    "profiles": {
      "researchmap": "https://researchmap.jp/masanorisakaguchi",
      "google_scholar": "https://scholar.google.com/citations?user=cYAH9bwAAAAJ",
      "orcid": "https://orcid.org/0000-0002-7211-9452",
      "j_global": "https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201201028969040510"
    },
    "research_field": "Life sciences — Cognitive neuroscience",
    "research_keywords": [
      "adult-born neurons",
      "memory",
      "sleep",
      "hippocampus",
      "in vivo brain imaging",
      "optogenetics",
      "deep learning"
    ],
    "research_keywords_ja": [
      "新生ニューロン",
      "記憶",
      "睡眠",
      "海馬",
      "生体脳イメージング",
      "光遺伝学",
      "深層学習"
    ],
    "education": [
      {
        "period": "1995-04 – 2001-03",
        "institution": "University of Tsukuba",
        "program": "School of Medicine"
      },
      {
        "period": "2001-04 – 2005-03",
        "institution": "University of Tsukuba",
        "program": "Graduate School of Comprehensive Human Sciences, doctoral course in medicine"
      }
    ],
    "degree": {
      "name": "PhD (Medicine)",
      "name_ja": "博士(医学)",
      "institution": "University of Tsukuba",
      "date": "2005-03"
    },
    "appointments": [
      {
        "period": "2026-01 –",
        "position": "Professor",
        "organization": "Department of Neurophysiology, Kobe University"
      },
      {
        "period": "2025-10 –",
        "position": "Visiting Researcher",
        "organization": "RIKEN Center for Brain Science"
      },
      {
        "period": "2022-04 – 2025-12",
        "position": "Associate Professor (tenured)",
        "organization": "Faculty of Medicine, University of Tsukuba"
      },
      {
        "period": "2018-10 – 2025-12",
        "position": "Associate Professor, PI",
        "organization": "International Institute for Integrative Sleep Medicine (IIIS), University of Tsukuba"
      },
      {
        "period": "2013-04 – 2018-09",
        "position": "Associate Professor, co-PI",
        "organization": "International Institute for Integrative Sleep Medicine (IIIS), University of Tsukuba"
      },
      {
        "period": "2011-04 – 2013-01",
        "position": "Special Postdoctoral Fellow (SPD)",
        "organization": "RIKEN"
      },
      {
        "period": "2010-10 – 2011-03",
        "position": "Researcher",
        "organization": "RIKEN Brain Science Institute"
      },
      {
        "period": "2009-04 – 2010-09",
        "position": "JSPS Overseas Research Fellow",
        "organization": "Japan Society for the Promotion of Science"
      },
      {
        "period": "2007-04 – 2009-03",
        "position": "Researcher (postdoctoral)",
        "organization": "The Hospital for Sick Children (SickKids), Toronto"
      },
      {
        "period": "2005-04 – 2007-03",
        "position": "Research Associate",
        "organization": "Department of Physiology, Keio University School of Medicine"
      }
    ],
    "awards": [
      {
        "date": "2025-10",
        "name": "Teacher's Award",
        "by": "University of Tsukuba"
      },
      {
        "date": "2022-10",
        "name": "Outstanding Faculty Award (優秀教員表彰)",
        "by": "University of Tsukuba"
      },
      {
        "date": "2016",
        "name": "Neuroscience 2016 Hot Topic",
        "by": "Society for Neuroscience",
        "title": "The role of adult born neurons in memory consolidation during sleep-wake cycles"
      },
      {
        "date": "2015",
        "name": "Excellent Presentation Award",
        "by": "The Adult Neurogenesis Conference"
      },
      {
        "date": "2014",
        "name": "Excellent Presentation Award",
        "by": "Homeodynamics in Clocks, Sleep and Metabolism Tokyo Translational Therapeutics Meeting",
        "title": "The role of adult born neurons during sleep"
      },
      {
        "date": "2008",
        "name": "Excellent Presentation Award; Travel Award",
        "by": "The Hospital for Sick Children"
      },
      {
        "date": "2007",
        "name": "Restracomp Award",
        "by": "The Hospital for Sick Children Research Institute"
      },
      {
        "date": "2004",
        "name": "Keystone Symposia Scholarship Award",
        "by": "Keystone Symposia"
      }
    ]
  },
  "members": [
    {
      "name": "Masanori Sakaguchi, MD, PhD",
      "role": "Professor & Chair",
      "group": "Principal Investigator"
    },
    {
      "name": "Yuto Momohara, PhD",
      "role": "Assistant Professor",
      "group": "Kobe campus"
    },
    {
      "name": "Mukhamad Sunardi, MD, PhD",
      "role": "Specially-Appointed Assistant Professor",
      "group": "Kobe campus"
    },
    {
      "name": "Kazuki Nagai",
      "role": "PhD Candidate",
      "group": "Kobe campus"
    },
    {
      "name": "Yume Yoshida",
      "role": "PhD Candidate — Oral & Maxillofacial Surgery",
      "group": "Kobe campus"
    },
    {
      "name": "Izumi Yamamoto",
      "role": "Administrative Officer",
      "group": "Kobe campus"
    },
    {
      "name": "Haruka Sekiba",
      "role": "Graduate Student — Frontier Medical Sciences, University of Tsukuba",
      "group": "Tsukuba campus"
    },
    {
      "name": "Iyo Koyanagi, PhD",
      "role": "University of Tsukuba — through September 2026",
      "group": "Tsukuba campus"
    },
    {
      "name": "Ikuko Sekiguchi",
      "role": "Secretary — University of Tsukuba (through September 2026)",
      "group": "Tsukuba campus"
    },
    {
      "name": "Yoshiharu Kim, MD, PhD",
      "role": "Visiting Professor (since April 2026) — Honorary Director, National Institute of Mental Health, NCNP",
      "group": "Visiting & Affiliated Members"
    },
    {
      "name": "Hiroyuki Kitagawa, PhD",
      "role": "Visiting Professor — Professor Emeritus, University of Tsukuba",
      "group": "Visiting & Affiliated Members"
    },
    {
      "name": "Makoh Miyakawa",
      "role": "Affiliated Student — Colorado College (Neuroscience)",
      "group": "Visiting & Affiliated Members"
    }
  ],
  "alumni": [
    {
      "name": "Deependra Kumar",
      "note": "First author, Neuron (2020); JSPS Postdoctoral Fellow for Research in Japan; now Assistant Professor in Masashi Yanagisawa's laboratory at the International Institute for Integrative Sleep Medicine, University of Tsukuba."
    },
    {
      "name": "Sakthivel Srinivasan",
      "note": "First author, Nature Communications (2025); JSPS Postdoctoral Fellow for Research in Japan; continues as a postdoctoral researcher in Paul Frankland's laboratory in Toronto, Canada."
    },
    {
      "name": "Pablo Vergara",
      "note": "First author, Nature Communications (2025); JSPS Postdoctoral Fellow for Research in Japan; now Assistant Professor, University of Yamanashi."
    },
    {
      "name": "Yuteng Wang",
      "note": "JSPS Postdoctoral Fellow for Research in Japan."
    }
  ],
  "training_record": "Researchers who joined the lab from outside Japan have published first-author papers in leading journals (Deependra Kumar, Neuron 2020; Sakthivel Srinivasan, Nature Communications 2025; Pablo Vergara, Nature Communications 2025), won JSPS Postdoctoral Fellowships for Research in Japan (Kumar, Srinivasan, Vergara and Yuteng Wang), and moved on to faculty and postdoctoral positions. Alumni span ten countries; English is the working language.",
  "contact": {
    "address": "Department of Neurophysiology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan",
    "email_display": "masakagu [at] med.kobe-u.ac.jp",
    "inquiries": "Research, collaboration and press inquiries go to Masanori Sakaguchi by email. Administrative inquiries (visits, scheduling) are routed via the same address.",
    "access": "Kusunoki Campus of Kobe University, about a 5-minute walk from Okurayama Station on the Kobe Municipal Subway (Seishin-Yamate Line).",
    "contact_page": "https://www.med.kobe-u.ac.jp/neurophy/contact.html",
    "access_page": "https://www.med.kobe-u.ac.jp/neurophy/access.html"
  },
  "positions": {
    "summary": "The lab welcomes researchers from any country as PhD students, postdoctoral fellows, research technicians, and short-term visiting scholars (one to six months). English is the working language; Japanese is encouraged but not required. PhD admission is through Kobe University Graduate School of Medicine (April and October intake). Postdoctoral applicants are supported in applying for the JSPS Research Fellowship (PD; Japanese nationals and permanent residents), the JSPS Postdoctoral Fellowship for Research in Japan (other nationalities), HFSP and EMBO fellowships.",
    "how_to_apply": "Email Masanori Sakaguchi (masakagu [at] med.kobe-u.ac.jp) with a brief cover letter stating the program (PhD / postdoc / visiting / tech), a CV with a publication list and two references, a one-page research statement (postdoc applicants only), and the preferred start date and any intended external fellowship. Most inquiries receive a reply within two weeks.",
    "page": "https://www.med.kobe-u.ac.jp/neurophy/positions.html"
  },
  "theme_descriptions": {
    "adult_neurogenesis_memory": "Adult-born neurons in the hippocampal dentate gyrus (and olfactory bulb) and their roles in forming, consolidating and clearing memories, studied with ablation, optogenetic silencing and in vivo calcium imaging in mice.",
    "rem_sleep_memory": "How REM sleep contributes to memory consolidation, including the reactivation of small neuronal ensembles during REM sleep and its timing relative to the theta rhythm.",
    "fear_memory_ptsd": "Rodent studies of contextual and cued fear memory — formation, generalization, extinction and reconsolidation — as a basis for understanding trauma-related memory in PTSD.",
    "sound_exposure_during_sleep": "Delivery of sounds during sleep to influence memory processing, from rodent experiments with conditioned auditory cues during NREM sleep to Sound Exposure during Sleep (SES) in people with PTSD. Human SES work is exploratory and is not an established treatment.",
    "sleep_staging_closed_loop_tools": "Software and devices that classify sleep stages automatically and in real time from EEG/EMG, and that trigger stage-specific interventions (closed loop) during sleep.",
    "imaging_tools": "Head-mounted miniature fluorescence microscopes and analysis software for recording and tracking the activity of the same neurons across sessions in freely moving animals.",
    "sleep_circuits": "Neural circuits in the brainstem and hippocampus that generate or regulate sleep states and sleep-related network activity.",
    "neural_stem_cells_galectin": "Biology of adult neural stem and progenitor cells, including the identification of Galectin-1 as a factor that promotes their proliferation and the signaling pathways that regulate them.",
    "neural_regeneration_transplantation": "Transplantation of neural stem/progenitor cells and other cells into injured or diseased central nervous system, aimed at regeneration.",
    "human_sleep_clinical": "Observational studies of human sleep, including sleep-rhythm signatures in people with PTSD.",
    "other": "Other studies by the PI and collaborators that do not fall under the main themes."
  },
  "citation": {
    "website": "Department of Neurophysiology, Kobe University Graduate School of Medicine. https://www.med.kobe-u.ac.jp/neurophy/",
    "papers": "Cite the original articles (DOI) rather than this website. The files publications.bib and publications.csl.json contain the bibliographic records."
  },
  "provenance": "Prepared by the Department of Neurophysiology, Kobe University Graduate School of Medicine. Quantitative statements were checked against the published articles.",
  "overview_ja": "神戸大学大学院医学系研究科 神経生理学分野は、睡眠中の脳がどのように記憶を固定するのかを研究しています。海馬で生まれ続ける新生ニューロンがレム睡眠中に記憶痕跡へ組み込まれる回路機構の解明、リアルタイムの睡眠ステージ判定、睡眠中の音による記憶の再活性化、そして PTSD を軸にした臨床応用への展開を、並行して進めています。",
  "key_papers": [
    "srinivasan-2025-nat-commun",
    "kumar-2020-neuron",
    "vergara-2025-natcommun",
    "arruda-carvalho-2011-jneurosci",
    "sakaguchi-2006-pnas",
    "purple-2017-scirep",
    "sekiba-2025-medrxiv",
    "ino-2026-medrxiv"
  ],
  "funding": [
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research (A) (KAKENHI)",
      "program_ja": "科学研究費助成事業 基盤研究(A)",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation and application of the memory consolidation mechanisms inherent in sleep dynamics",
      "title_ja": "睡眠ダイナミクスに内在する記憶固定化メカニズムの解明と応用",
      "start_year": 2026,
      "end_year": 2028,
      "grant_number": "26H02428",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-26H02428/"
    },
    {
      "funder_en": "Japan Science and Technology Agency (JST)",
      "funder_ja": "科学技術振興機構（JST）",
      "program_en": "Strategic Basic Research Programs, CREST",
      "program_ja": "戦略的創造研究推進事業 CREST",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": null,
      "title_ja": null,
      "start_year": 2026,
      "end_year": 2027,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Takeda Science Foundation",
      "funder_ja": "武田科学振興財団",
      "program_en": "Specified Research Grant",
      "program_ja": "特定研究助成",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": null,
      "title_ja": null,
      "start_year": 2026,
      "end_year": null,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Agency for Medical Research and Development (AMED)",
      "funder_ja": "日本医療研究開発機構（AMED）",
      "program_en": "Translational Research Program, Medical Startup Support Program, Seeds S1",
      "program_ja": "橋渡し研究プログラム 大学発医療系スタートアップ支援プログラム シーズS1",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Regulatory approval, implementation and commercialisation of a closed-loop acoustic stimulation medical device delivering SES (Sound Exposure during Sleep) therapy",
      "title_ja": "SES（睡眠中音エクスポージャー）治療を実装する閉ループ音刺激医療機器の薬事・実用化と事業化",
      "start_year": 2026,
      "end_year": null,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Transformative Research Areas (B), Organizing Group (KAKENHI)",
      "program_ja": "科学研究費助成事業 学術変革領域研究(B) 総括班",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": "Administration of \"Manipulation of the Umwelt through the use of sound\"",
      "title_ja": "「音による環世界マニピュレーション」研究の総括",
      "start_year": 2024,
      "end_year": 2026,
      "grant_number": "25K24828",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-ORGANIZER-25K24828/"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Transformative Research Areas (B), Planned Research (KAKENHI)",
      "program_ja": "科学研究費助成事業 学術変革領域研究(B) 計画研究",
      "role": "planned_research_pi",
      "role_ja": "計画研究 研究代表者",
      "title_en": "Manipulation of the Umwelt by sound stimulation during sleep",
      "title_ja": "睡眠中の音刺激による環世界マニピレーション",
      "start_year": 2024,
      "end_year": 2026,
      "grant_number": "25K24831",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PLANNED-25K24831/"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research (C) (KAKENHI)",
      "program_ja": "科学研究費助成事業 基盤研究(C)",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": "Real-time motif detection from calcium imaging",
      "title_ja": "カルシウムイメージングからのリアルタイムモチーフ発見技術の開発",
      "start_year": 2024,
      "end_year": 2026,
      "grant_number": "24K10470",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-24K10470/"
    },
    {
      "funder_en": "Japan Agency for Medical Research and Development (AMED)",
      "funder_ja": "日本医療研究開発機構（AMED）",
      "program_en": "Translational Research Program, Seeds preF",
      "program_ja": "橋渡し研究プログラム シーズpreF",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Development of a novel treatment for PTSD using sound stimulation during sleep",
      "title_ja": "睡眠中の音刺激によるPTSDの新規治療法の開発",
      "start_year": 2024,
      "end_year": 2024,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research (B) (KAKENHI)",
      "program_ja": "科学研究費助成事業 基盤研究(B)",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Function of fear memory retrieval during REM sleep",
      "title_ja": "レム睡眠中に恐怖記憶が再想起する意義の解明",
      "start_year": 2023,
      "end_year": 2025,
      "grant_number": "23K27475",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-23K27475/"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Fund for the Promotion of Joint International Research (International Leading Research) (KAKENHI)",
      "program_ja": "科学研究費助成事業 国際共同研究加速基金（国際先導研究）",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": "Deciphering the mysteries of sleep: creating a global network of sleep neuroscientists",
      "title_ja": "睡眠の謎に挑む：睡眠神経科学者のグローバルネットワーク構築",
      "start_year": 2022,
      "end_year": 2028,
      "grant_number": "22K21351",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22K21351/"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research (A) (KAKENHI)",
      "program_ja": "科学研究費助成事業 基盤研究(A)",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": "Molecular research and treatment of fear memory in PTSD",
      "title_ja": "PTSDの恐怖記憶と情動反応の分子基盤の解明と治療",
      "start_year": 2022,
      "end_year": 2024,
      "grant_number": "22H00469",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22H00469/"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for JSPS Fellows (KAKENHI)",
      "program_ja": "科学研究費助成事業 特別研究員奨励費（外国人特別研究員）",
      "role": "other",
      "role_ja": "受入研究者",
      "title_en": "Elucidation of the mechanism by which adult-born neurons consolidate memory during sleep",
      "title_ja": "新生ニューロンが睡眠中に記憶を固定化するメカニズムの解明",
      "start_year": 2022,
      "end_year": 2023,
      "grant_number": "22KF0047",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22KF0047/"
    },
    {
      "funder_en": "Japan Agency for Medical Research and Development (AMED)",
      "funder_ja": "日本医療研究開発機構（AMED）",
      "program_en": "Translational Research Program, Seeds A",
      "program_ja": "橋渡し研究プログラム シーズA",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": null,
      "title_ja": null,
      "start_year": 2022,
      "end_year": 2022,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Uehara Memorial Foundation",
      "funder_ja": "上原記念生命科学財団",
      "program_en": "Specified Research Grant",
      "program_ja": "特定研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of the operating principles of consciousness based on synchronous brain activity",
      "title_ja": "脳の同期活動をもとにした意識の動作原理の解明",
      "start_year": 2021,
      "end_year": 2023,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Agency for Medical Research and Development (AMED)",
      "funder_ja": "日本医療研究開発機構（AMED）",
      "program_en": "Brain and Mind Research Promotion Program (Cross-disciplinary and Exploratory Brain Research Project)",
      "program_ja": "脳とこころの研究推進プログラム（領域横断的かつ萌芽的脳研究プロジェクト）",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Research and development on the operating principles of consciousness",
      "title_ja": "意識の動作原理に関する研究開発",
      "start_year": 2021,
      "end_year": 2023,
      "grant_number": null,
      "public_url": "https://www.amed.go.jp/koubo/15/01/1501C_00014.html"
    },
    {
      "funder_en": "Goho Life Sciences International Fund",
      "funder_ja": "公益信託 五峯ライフサイエンス国際基金",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of the mechanism of memory consolidation during sleep",
      "title_ja": "睡眠中の記憶固定化の仕組みの解明",
      "start_year": 2021,
      "end_year": 2022,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Transformative Research Areas (A), Publicly Offered Research (KAKENHI)",
      "program_ja": "科学研究費助成事業 学術変革領域研究(A) 公募研究",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Function of synapse pruning in the regenerating memory circuit",
      "title_ja": "再編成を続ける記憶回路におけるシナプス刈り込みの意義の解明",
      "start_year": 2021,
      "end_year": 2022,
      "grant_number": "21H05674",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PUBLICLY-21H05674/"
    },
    {
      "funder_en": "Mitsubishi Foundation",
      "funder_ja": "三菱財団",
      "program_en": "Research Grants in the Natural Sciences",
      "program_ja": "自然科学研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Pattern separation mechanism based on the interaction of new and old neurons during sleep",
      "title_ja": "睡眠中の新旧ニューロンの相互作用によるパターン分離機構の解明",
      "start_year": 2021,
      "end_year": 2022,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Takeda Science Foundation",
      "funder_ja": "武田科学振興財団",
      "program_en": "Life Science Research Grant",
      "program_ja": "生命科学研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Failure of plastic neural circuits underlying anxiety disorders",
      "title_ja": "不安障害の背後にある可塑的な神経回路の機能破綻",
      "start_year": 2021,
      "end_year": null,
      "grant_number": null,
      "public_url": "https://takeda-sci.or.jp/research/doc/2021_list.pdf"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research (B) (KAKENHI)",
      "program_ja": "科学研究費助成事業 基盤研究(B)",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Significance of synaptic plasticity for memory consolidation during sleep",
      "title_ja": "睡眠中の記憶固定化におけるシナプス可塑性の意義の解明",
      "start_year": 2020,
      "end_year": 2022,
      "grant_number": "20H03552",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-20H03552/"
    },
    {
      "funder_en": "Japan Agency for Medical Research and Development (AMED)",
      "funder_ja": "日本医療研究開発機構（AMED）",
      "program_en": "Moonshot Research and Development Program, Goal 7",
      "program_ja": "ムーンショット型研究開発事業 目標7",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": "Sleep and hibernation: next-generation medicine opened up by elucidating and manipulating two kinds of 'sleep'",
      "title_ja": "睡眠と冬眠：2つの「眠り」の解明と操作が拓く新世代医療の展開",
      "start_year": 2020,
      "end_year": null,
      "grant_number": null,
      "public_url": "https://www.amed.go.jp/koubo/18/03/1803C_00003.html"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for JSPS Fellows (KAKENHI)",
      "program_ja": "科学研究費助成事業 特別研究員奨励費（外国人特別研究員）",
      "role": "other",
      "role_ja": "受入研究者",
      "title_en": "Role of SRF in memory consolidation during REM sleep",
      "title_ja": "レム睡眠中の記憶固定化におけるSRFの役割",
      "start_year": 2019,
      "end_year": 2021,
      "grant_number": "19F19310",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19F19310/"
    },
    {
      "funder_en": "Takeda Science Foundation",
      "funder_ja": "武田科学振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Erasing traumatic memory during sleep by optogenetics",
      "title_ja": "光遺伝学による睡眠中のトラウマ記憶消去",
      "start_year": 2017,
      "end_year": 2017,
      "grant_number": null,
      "public_url": "https://takeda-sci.or.jp/research/doc/2017_list.pdf"
    },
    {
      "funder_en": "Japan Science and Technology Agency (JST)",
      "funder_ja": "科学技術振興機構（JST）",
      "program_en": "Strategic Basic Research Programs, CREST",
      "program_ja": "戦略的創造研究推進事業 CREST（研究領域「光の特性を活用した生命機能の時空間制御技術の開発と応用」）",
      "role": "co_investigator",
      "role_ja": "研究分担者",
      "title_en": "Integrated analysis of sleep function and control mechanisms using light",
      "title_ja": "光を用いた睡眠の機能と制御機構の統合的解析",
      "start_year": 2016,
      "end_year": 2020,
      "grant_number": null,
      "public_url": "https://www.jst.go.jp/kisoken/crest/project/1111091/1111091_2016.html"
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Young Scientists (B) (KAKENHI)",
      "program_ja": "科学研究費助成事業 若手研究(B)",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Memory trace consolidated by new-born neurons",
      "title_ja": "新生ニューロンが作る記憶痕跡",
      "start_year": 2016,
      "end_year": 2019,
      "grant_number": "16K18359",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-16K18359/"
    },
    {
      "funder_en": "Inamori Foundation",
      "funder_ja": "稲盛財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Function of adult-born neurons in memory during sleep revealed by optogenetics",
      "title_ja": "光遺伝学にて明らかにする睡眠中の記憶における新生ニューロンの機能",
      "start_year": 2016,
      "end_year": 2016,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Shimadzu Science Foundation",
      "funder_ja": "島津科学技術振興財団",
      "program_en": "Research and Development Grant",
      "program_ja": "研究開発助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Identification of the molecular entity of sleepiness by mass spectrometry and optogenetics",
      "title_ja": "質量分析計と光遺伝学による眠気の分子実体の同定",
      "start_year": 2016,
      "end_year": 2016,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Kanehara Ichiro Memorial Foundation",
      "funder_ja": "金原一郎記念医学医療振興財団",
      "program_en": "Research Grant for Basic Medical Science",
      "program_ja": "基礎医学医療研究助成金",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Molecular mechanism of sleep-dependent memory consolidation revealed by adult neurogenesis",
      "title_ja": "成体脳のニューロン新生から明らかにする睡眠依存的な記憶固定化の分子メカニズム",
      "start_year": 2016,
      "end_year": 2016,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "SENSHIN Medical Research Foundation",
      "funder_ja": "先進医薬研究振興財団",
      "program_en": "Psychopharmacology Research Grant",
      "program_ja": "精神薬療分野 一般研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Sleep-stage-dependent function of adult-born neurons in the generalization of PTSD",
      "title_ja": "PTSD の汎化における睡眠期依存的な新生ニューロンの機能",
      "start_year": 2016,
      "end_year": 2016,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for JSPS Fellows (KAKENHI)",
      "program_ja": "科学研究費助成事業 特別研究員奨励費（外国人特別研究員）",
      "role": "other",
      "role_ja": "受入研究者",
      "title_en": "Integration of adult-born neurons into memory circuits during sleep",
      "title_ja": "睡眠中の、新生ニューロンの記録回路への組み込み",
      "start_year": 2015,
      "end_year": 2017,
      "grant_number": "15F15408",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-15F15408/"
    },
    {
      "funder_en": "Research Foundation for Opto-Science and Technology",
      "funder_ja": "光科学技術研究振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Function of adult-born neurons in memory circuit formation during sleep revealed by light",
      "title_ja": "光にて明らかにする、睡眠中の新生ニューロンの記憶回路形成への機能",
      "start_year": 2015,
      "end_year": 2016,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Kato Memorial Bioscience Foundation",
      "funder_ja": "加藤記念バイオサイエンス振興財団",
      "program_en": "Kato Memorial Research Grant",
      "program_ja": "加藤記念研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "The role of sleep in memory consolidation",
      "title_ja": "睡眠が記憶の固定化に果たす役割",
      "start_year": 2015,
      "end_year": 2016,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Life Science Foundation of Japan",
      "funder_ja": "ライフサイエンス振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Basic research toward regenerative therapy of the central nervous system using adult-born neurons",
      "title_ja": "新生ニューロンを用いた中枢神経再生治療のための基礎研究",
      "start_year": 2015,
      "end_year": 2015,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Kowa Life Science Foundation",
      "funder_ja": "興和生命科学振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of memory formation during sleep by optical control of neurons regenerating in the brain",
      "title_ja": "脳内で再生するニューロンの光制御による、睡眠中の記憶形成過程の解明",
      "start_year": 2015,
      "end_year": 2015,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Uehara Memorial Foundation",
      "funder_ja": "上原記念生命科学財団",
      "program_en": "Research Incentive Grant",
      "program_ja": "研究奨励金",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of memory formation mechanisms during sleep using light",
      "title_ja": "光による睡眠中の記憶形成機構の解明",
      "start_year": 2015,
      "end_year": 2015,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "SENSHIN Medical Research Foundation",
      "funder_ja": "先進医薬研究振興財団",
      "program_en": "Psychopharmacology Research Grant for Young Investigators",
      "program_ja": "精神薬療分野 若手研究者助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Excitation of adult-born neurons during REM sleep is required for traumatic memory formation",
      "title_ja": "REM 睡眠中の新生ニューロンの興奮が、トラウマ記憶の形成に必要である",
      "start_year": 2015,
      "end_year": 2015,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Kanae Foundation for the Promotion of Medical Science",
      "funder_ja": "かなえ医薬振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Integration of adult-born neurons into existing circuits for central nervous system regeneration",
      "title_ja": "中枢神経再生のための、新生ニューロンの既存回路への統合機構の解明",
      "start_year": 2015,
      "end_year": 2015,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research on Innovative Areas, Publicly Offered Research (KAKENHI)",
      "program_ja": "科学研究費助成事業 新学術領域研究（研究領域提案型）公募研究",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Function of the activation of adult-born neurons during sleep in memory",
      "title_ja": "睡眠中の新生ニューロンの活性化が記憶に及ぼす機能",
      "start_year": 2014,
      "end_year": 2015,
      "grant_number": "26115502",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PUBLICLY-26115502/"
    },
    {
      "funder_en": "Japan Applied Enzyme Association",
      "funder_ja": "日本応用酵素協会",
      "program_en": "Research Grant on the Causes and Pathology of Adult Diseases",
      "program_ja": "成人病の原因・病態の解明に関する研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Pathophysiology of memory information processing in aging",
      "title_ja": "加齢における記憶情報処理機構の病態生理解明",
      "start_year": 2013,
      "end_year": 2017,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Scientific Research on Innovative Areas, Publicly Offered Research (KAKENHI)",
      "program_ja": "科学研究費助成事業 新学術領域研究（研究領域提案型）公募研究",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Pathophysiology of memory information processing in post-traumatic stress disorder (PTSD)",
      "title_ja": "心的外傷後ストレス障害(PTSD)における記憶情報処理の病態生理",
      "start_year": 2013,
      "end_year": 2014,
      "grant_number": "25116530",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PUBLICLY-25116530/"
    },
    {
      "funder_en": "Brain Science Foundation",
      "funder_ja": "ブレインサイエンス振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Pathophysiology of fear memory information processing in PTSD",
      "title_ja": "PTSD における恐怖記憶情報処理の病態解明",
      "start_year": 2013,
      "end_year": 2013,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Young Scientists (B) (KAKENHI)",
      "program_ja": "科学研究費助成事業 若手研究(B)",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Memory transfer across neural networks",
      "title_ja": "脳内における記憶情報の転送メカニズムの解明",
      "start_year": 2012,
      "end_year": 2013,
      "grant_number": "24700340",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-24700340/"
    },
    {
      "funder_en": "Research Foundation for Opto-Science and Technology",
      "funder_ja": "光科学技術研究振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of memory transfer mechanisms in the brain by optogenetics",
      "title_ja": "光遺伝学による、脳内記憶情報の転送メカニズムの解明",
      "start_year": 2011,
      "end_year": 2012,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Takeda Science Foundation",
      "funder_ja": "武田科学振興財団",
      "program_en": "Research Grant",
      "program_ja": "研究助成",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of the mechanism of memory information transfer in the brain",
      "title_ja": "記憶情報の脳内転送メカニズムの解明",
      "start_year": 2011,
      "end_year": 2011,
      "grant_number": null,
      "public_url": "https://takeda-sci.or.jp/research/doc/2011_list.pdf"
    },
    {
      "funder_en": "Uehara Memorial Foundation",
      "funder_ja": "上原記念生命科学財団",
      "program_en": "Research Incentive Grant",
      "program_ja": "研究奨励金",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Elucidation of the transfer mechanism of memory information in the brain",
      "title_ja": "脳内の記憶情報の転送メカニズムの解明",
      "start_year": 2011,
      "end_year": 2011,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Overseas Research Fellowships",
      "program_ja": "海外特別研究員",
      "role": "other",
      "role_ja": "特別研究員（本人）",
      "title_en": "Role of adult neurogenesis in learning and memory in the adult central nervous system",
      "title_ja": "成体中枢神経系におけるニューロン新生の学習・記憶における役割",
      "start_year": 2009,
      "end_year": 2010,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "The Hospital for Sick Children (SickKids), Toronto",
      "funder_ja": "トロント小児病院（SickKids）",
      "program_en": "Restracomp Postdoctoral Fellowship",
      "program_ja": "RESTRACOMP 博士研究員フェローシップ",
      "role": "other",
      "role_ja": "フェロー（本人）",
      "title_en": null,
      "title_ja": null,
      "start_year": 2007,
      "end_year": 2008,
      "grant_number": null,
      "public_url": null
    },
    {
      "funder_en": "Japan Society for the Promotion of Science (JSPS)",
      "funder_ja": "日本学術振興会（JSPS）",
      "program_en": "Grant-in-Aid for Young Scientists (Start-up) (KAKENHI)",
      "program_ja": "科学研究費助成事業 若手研究（スタートアップ）",
      "role": "principal_investigator",
      "role_ja": "研究代表者",
      "title_en": "Functional analysis of glycan molecules in adult central nervous system stem cells",
      "title_ja": "成体中枢神経幹細胞における糖鎖分子の機能解析",
      "start_year": 2006,
      "end_year": 2007,
      "grant_number": "18890186",
      "public_url": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-18890186/"
    }
  ],
  "patents": {
    "registered": [
      {
        "office": "JP",
        "number": "7299610",
        "title_en": "Small imaging device",
        "title_ja": "小型撮像装置",
        "year_granted": 2023
      },
      {
        "office": "JP",
        "number": "7321511",
        "title_en": "Determination device, light irradiation device, and program",
        "title_ja": "判定装置、光照射装置、及びプログラム",
        "year_granted": 2023
      },
      {
        "office": "US",
        "number": "7,662,385",
        "title_en": "Agent for inhibiting proliferation of neural stem cells",
        "title_ja": "神経幹細胞の増殖抑制剤",
        "year_granted": 2010
      },
      {
        "office": "US",
        "number": "7,785,596",
        "title_en": "Methods for enhancing survival and/or proliferation of neural stem cells and neurite extension enhancers therefor, pharmaceutical compositions containing neural stem cells, assay methods and screening methods",
        "title_ja": "神経幹細胞の生存・増殖を促進する方法、神経突起伸長促進剤、神経幹細胞を含む医薬組成物、測定法およびスクリーニング法",
        "year_granted": 2010
      }
    ],
    "filed_statement_en": "We have also filed patent applications on technologies related to sleep. Their details will be posted after the applications are published.",
    "filed_statement_ja": "睡眠に関わる技術について、ほかにも特許を出願している。内容は出願公開の後に掲載する。"
  }
}