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業績ACHIEVEMENT

2016年度

  • Ito S, Yano I, Hashi S, Tsuda M, Sugimoto M, Yonezawa A, Ikeda A, Matsubara K.
    Population pharmacokinetic modeling of levetiracetam in pediatric and adult patients with epilepsy by using routinely monitored data.
    Ther Drug Monit, 38(3):371-8 (2016)
  • Onoue H, Yano I, Tanaka A, Itohara K, Hanai A, Ishiguro H, Motohashi H, Masuda S, Matsubara K.
    Significant effect of age on docetaxel pharmacokinetics in Japanese female breast cancer patients by using the population modeling approach.
    Eur J Clin Pharmacol, 72(6):703-10 (2016)
  • Yoshimatsu H, Yonezawa A, Yamanishi K, Yao Y, Sugano K, Nakagawa S, Imai S, Omura T, Nakagawa T, Yano I, Masuda S, Inui K, Matsubara K.
    Disruption of Slc52a3 gene causes neonatal lethality with riboflavin deficiency in mice.
    Sci Rep, 6:27557 (2016)
  • Zhou Z, Yano I, Odaka S., Morita Y, Shizuta S, Hayano M, Kimura T, Akaike A, Inui K, Matsubara K.
    Effect of vitamin K2 on the anticoagulant activity of warfarin during the perioperative period of catheter ablation: Population analysis of retrospective clinical data.
    J Pharm Health Care Sci , 2,17 (2016)
  • Tanaka A, Yano I, Shinsako K, Sato E, Fukudo M, Masuda S, Yamasaki T, Kamba T, Ogawa O, Matsubara K.
    Population pharmacokinetics of everolimus in relation to clinical outcomes in patients with advanced renal cell carcinoma.
    Ther Drug Monit , 38:663-9 (2016)
  • Sato S, Jung H, Nakagawa T, Pawlosky R, Takeshima T, Lee WR, Sakiyama H, Laxman S, Wynn RM, Tu BP, MacMillan JB, De Brabander JK, Veech RL, Uyeda K.
    Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
    J Biol Chem , 291:10515-27 (2016)
  • Totsuka R, Kondo T, Matsubara S, Hirai M, Kurebayashi Y.
    Effects of VLA-1 Blockade on Experimental Inflammation in Mice.
    Kobe J Med Sci , 62(2):E27-37 (2016)
  • Mori H, Arita K, Yamaguchi T, Hirai M, Kurebayashi Y.
    Effects of Topical Application of Betamethasone on Imiquimod-induced Psoriasis-like Skin Inflammation in Mice.
    Kobe J Med Sci, 62(4):E79-E88 (2016)
  • Nakamura T, Takahashi M, Niigata R, Yamashita K, Kume M, Hirai M, Yasui H.
    Changes in blood concentrations of trace metals in cancer patients receiving cisplatin-based chemotherapy.
    Biomed Rep. 5:737-744 (2016)
  • Kimura T, Ogura F, Yamamoto K, Uda A, Nishioka T, Kume M, Makimoto H, Yano I, Hirai M.
    Potentially inappropriate medications in elderly Japanese patients: effects of pharmacists' assessment and intervention based on Screening Tool of Older Persons' Potentially Inappropriate Prescriptions criteria ver.2.
    J Clin Pharm Ther. 42:209-214 (2017)
  • Otani Y, Yonezawa A, Tsuda M, Imai S, Ikemi Y, Nakagawa S, Omura T, Nakagawa T, Yano I, Matasubara K.
    Time-dependent structural alteration of rituximab analyzed by LC/TOF-MS after a systemic administration to rats.
    PLoS One , 12(1):e0169588 (2017)
  • Takeuchi M, Yano I, Ito S, Sugimoto M, Yamamoto S, Yonezawa A, Ikeda A, Matsubara K.
    Population pharmacokinetics of topiramate in Japanese pediatric and adult patients with epilepsy using routinely monitored data.
    Ther Drug Monit , 39:124-31 (2017)
  • Kawara F, Fujita T, Morita Y, Uda A, Masuda A, Saito M, Ooi M, Ishida T, Kondo Y, Yoshida S, Okuno T, Yano Y, Yoshida M, Kutsumi H, Hayakumo T, Yamashita K, Hirano T, Hirai M, Azuma T.
    Factors ssociated with residual gastroesophageal reflux disease symptoms in patients receiving proton pump inhibitor maintenance therapy.
    World J Gastroenterol , 23(11):2060-2067 (2017)



2015年度

  • Ioroi T, Kakuma T, Sakashita A, Miki Y, Ohtagaki K, Fujiwara Y, Utsubo Y, Nishimura Y, Hirai M.
    Data analysis methods for assessing palliative care interventions in one-group pre?post studies.
    SAGE Open Medicine, 3:2050312115621313(2015)
  • Mizumoto A, Yamamoto K, Nakayama Y, Takara K, Nakagawa T, Hirano T, Hirai M.
    Induction of epithelial-mesenchymal transition via activation of epidermal growth factor receptor constitutes to sunitinib resistance in human renal cell carcinoma cell lines.
    J Pharmacol Exp Ther. 355(2):152-8 (2015)
  • Yamamoto K, Shichiri H, Uda A, Yamashita K, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Hirai M.
    Apoptotic Effects of the Extracts of Cordyceps militaris via Erk Phosphorylation in a Renal Cell Carcinoma Cell Line.
    Phytother Res. 29(5):707-13 (2015)
  • Yamamoto K, Ioroi T, Kanaya K, Shinomiya K, Komoto S, Hirata S, Harada K, Watanabe A, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Miyake H, Fujisawa M, Hirai M.
    STAT3 polymorphism rs4796793 may be a predictive factor of tumor response to multiple tyrosine kinase inhibitors in metastatic renal cell carcinoma in Japanese population.
    Med Oncol, 33(3):24 (2016)
  • Yamamoto K, Shinomiya K, Ioroi T, Hirata S, Harada K, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Bito T, Nishigori C, Miyake H, Fujisawa M, Hirai M.
    Association of single nucleotide polymorphisms in STAT3 with hand-foot skin reactions in patients with metastatic renal cell carcinoma treated with multiple tyrosine kinase inhibitors: a retrospective analysis in Japanese patients.
    Target Oncol. 11(1):93-9 (2016)


2014年度





2013年度





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2011年度





2010年度




バナースペース

薬物動態学・薬剤学分野

〒650-0017
兵庫県神戸市中央区楠町7丁目5-2
神戸大学医学部附属病院 薬剤部

TEL: 078-382-6659
FAX: 078-382-6702
E-mail: yakuken@med.kobe-u.ac.jp