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業績ACHIEVEMENT

2017年度

  • Mizuta N, Nakagawa T, Yamamoto K, Nishioka T, Kume M, Makimoto H, Yano I, Minami H, HiraiM.
    Compatibility and stability of nab-paclitaxel in combination with other drugs.
    Kobe J Med Sci, 63(1): E9-E16 (2017)
  • Katada Y, Nakagawa S, Minakata K, Odaka M, Taue H, Sato Y, Yonezawa A, Kayano Y, Yano I, Nakatsu T, Sakamoto K, Uehara K, Sakaguchi H, Yamazaki K, Minatoya K, Sakata R, Matsubara K.
    Efficacy of a protocol-based pharmacotherapy management on anticoagulation with warfarin for patients with cardiovascular surgery.
    J Clin Pharmacol Ther, 42(5):591-597 (2017)
  • Yamamoto K, Shichiri H, Ishida T, Kaku K, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Bito T, Nishigori C, Yano I, Hirai M.
    Effects of ascorbyl-2-phosphate magnesium on human keratinocyte toxicity and pathological changes by sorafenib.
    Bio Pharm Bull, 40(9):1530-1536 (2017)
  • Hanai A, Ishiguro, H, Takashi. Sozu T, Tsuda M, Yano I, Nakagawa T, Imai S, Hamabe Y, Toi M, Arai H, Tsuboyama T.
    Effects of cryotherapy on objective and subjective symptoms of paclitaxel-induced neuropathy: Prospective self-controlled trial.
    J Natl Cancer Inst, 110(2): djx178 (2017)
  • Yoshimura K, Yano I, Yamamoto T, Kawanishi M, Isomoto Y, Yonezawa A, Kondo T, Takaori-Kondo A, Matsubara K.
    Population pharmacokinetics and pharmacodynamics of mycophenolic acid using the prospective data in patients undergoing hematopoietic stem cell transplantation.
    Bone Marrow Transplant, 53(1):44-51 (2018).
  • Watanabe A, Yamamoto K, Ioroi T, Hirata S, Harada K, Miyake H, Fujisawa M, Nakagawa T, Yano I, Hirai M.
    Association of Single Nucleotide Polymorphisms in STAT3, ABCB1, and ABCG2 with Stomatitis in Patients with Metastatic Renal Cell Carcinoma Treated with Sunitinib: A Retrospective Analysis in Japanese Patients.
    Biol Pharm Bull, 40(4):458-464 (2017)
  • Shichiri H, Yamamoto K, Tokura M, Ishida T, Uda A, Bito T, Nishigori C, Nakagawa T, Hirano T, Yano I, Hirai M.
    Prostaglandin E1 reduces the keratinocyte toxicity of sorafenib by maintaining signal transducer and activator of transcription 3 (STAT3) activity and enhancing the cAMP response element binding protein (CREB) activity.
    Biochem Biophys Res Commun, 485(2):227-233 (2017)
  • Ioroi T, Furukawa J, Kume M, Hirata S, Utsubo Y, Mizuta N, Miyake H, Fujisawa M, Hirai M.
    Phase II study of palonosetron, aprepitant and dexamethasone to prevent nausea and vomiting induced by multiple-day emetogenic chemotherapy.
    Support Care Cancer, doi: 10.1007/s00520-017-3967-2 (2017)
  • Kimura T, Uda A, Sakaue T, Yamashita K, Nishioka T, Nishimura S, Ebisawa K, Nagata M, Ohji G, Nakamura T, Koike C, Kusuki M, Ioroi T, Mukai A, Abe Y, Yoshida H, Hirai M, Arakawa S, Yano I, Iwata K, Tokimatsu I.
    Long-term efficacy of comprehensive multidisciplinary antibiotic stewardship programs centered on weekly prospective audit and feedback. Infection. doi:10.1007/s15010-017-1099-8 (2017)



2016年度

  • Ito S, Yano I, Hashi S, Tsuda M, Sugimoto M, Yonezawa A, Ikeda A, Matsubara K.
    Population pharmacokinetic modeling of levetiracetam in pediatric and adult patients with epilepsy by using routinely monitored data.
    Ther Drug Monit, 38(3):371-8 (2016)
  • Onoue H, Yano I, Tanaka A, Itohara K, Hanai A, Ishiguro H, Motohashi H, Masuda S, Matsubara K.
    Significant effect of age on docetaxel pharmacokinetics in Japanese female breast cancer patients by using the population modeling approach.
    Eur J Clin Pharmacol, 72(6):703-10 (2016)
  • Yoshimatsu H, Yonezawa A, Yamanishi K, Yao Y, Sugano K, Nakagawa S, Imai S, Omura T, Nakagawa T, Yano I, Masuda S, Inui K, Matsubara K.
    Disruption of Slc52a3 gene causes neonatal lethality with riboflavin deficiency in mice.
    Sci Rep, 6:27557 (2016)
  • Zhou Z, Yano I, Odaka S., Morita Y, Shizuta S, Hayano M, Kimura T, Akaike A, Inui K, Matsubara K.
    Effect of vitamin K2 on the anticoagulant activity of warfarin during the perioperative period of catheter ablation: Population analysis of retrospective clinical data.
    J Pharm Health Care Sci , 2,17 (2016)
  • Tanaka A, Yano I, Shinsako K, Sato E, Fukudo M, Masuda S, Yamasaki T, Kamba T, Ogawa O, Matsubara K.
    Population pharmacokinetics of everolimus in relation to clinical outcomes in patients with advanced renal cell carcinoma.
    Ther Drug Monit , 38:663-9 (2016)
  • Sato S, Jung H, Nakagawa T, Pawlosky R, Takeshima T, Lee WR, Sakiyama H, Laxman S, Wynn RM, Tu BP, MacMillan JB, De Brabander JK, Veech RL, Uyeda K.
    Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR.
    J Biol Chem , 291:10515-27 (2016)
  • Totsuka R, Kondo T, Matsubara S, Hirai M, Kurebayashi Y.
    Effects of VLA-1 Blockade on Experimental Inflammation in Mice.
    Kobe J Med Sci , 62(2):E27-37 (2016)
  • Mori H, Arita K, Yamaguchi T, Hirai M, Kurebayashi Y.
    Effects of Topical Application of Betamethasone on Imiquimod-induced Psoriasis-like Skin Inflammation in Mice.
    Kobe J Med Sci, 62(4):E79-E88 (2016)
  • Nakamura T, Takahashi M, Niigata R, Yamashita K, Kume M, Hirai M, Yasui H.
    Changes in blood concentrations of trace metals in cancer patients receiving cisplatin-based chemotherapy.
    Biomed Rep. 5:737-744 (2016)
  • Kimura T, Ogura F, Yamamoto K, Uda A, Nishioka T, Kume M, Makimoto H, Yano I, Hirai M.
    Potentially inappropriate medications in elderly Japanese patients: effects of pharmacists' assessment and intervention based on Screening Tool of Older Persons' Potentially Inappropriate Prescriptions criteria ver.2.
    J Clin Pharm Ther. 42:209-214 (2017)
  • Otani Y, Yonezawa A, Tsuda M, Imai S, Ikemi Y, Nakagawa S, Omura T, Nakagawa T, Yano I, Matasubara K.
    Time-dependent structural alteration of rituximab analyzed by LC/TOF-MS after a systemic administration to rats.
    PLoS One , 12(1):e0169588 (2017)
  • Takeuchi M, Yano I, Ito S, Sugimoto M, Yamamoto S, Yonezawa A, Ikeda A, Matsubara K.
    Population pharmacokinetics of topiramate in Japanese pediatric and adult patients with epilepsy using routinely monitored data.
    Ther Drug Monit , 39:124-31 (2017)
  • Kawara F, Fujita T, Morita Y, Uda A, Masuda A, Saito M, Ooi M, Ishida T, Kondo Y, Yoshida S, Okuno T, Yano Y, Yoshida M, Kutsumi H, Hayakumo T, Yamashita K, Hirano T, Hirai M, Azuma T.
    Factors ssociated with residual gastroesophageal reflux disease symptoms in patients receiving proton pump inhibitor maintenance therapy.
    World J Gastroenterol , 23(11):2060-2067 (2017)



2015年度

  • Ioroi T, Kakuma T, Sakashita A, Miki Y, Ohtagaki K, Fujiwara Y, Utsubo Y, Nishimura Y, Hirai M.
    Data analysis methods for assessing palliative care interventions in one-group pre?post studies.
    SAGE Open Medicine, 3:2050312115621313(2015)
  • Mizumoto A, Yamamoto K, Nakayama Y, Takara K, Nakagawa T, Hirano T, Hirai M.
    Induction of epithelial-mesenchymal transition via activation of epidermal growth factor receptor constitutes to sunitinib resistance in human renal cell carcinoma cell lines.
    J Pharmacol Exp Ther. 355(2):152-8 (2015)
  • Yamamoto K, Shichiri H, Uda A, Yamashita K, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Hirai M.
    Apoptotic Effects of the Extracts of Cordyceps militaris via Erk Phosphorylation in a Renal Cell Carcinoma Cell Line.
    Phytother Res. 29(5):707-13 (2015)
  • Yamamoto K, Ioroi T, Kanaya K, Shinomiya K, Komoto S, Hirata S, Harada K, Watanabe A, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Miyake H, Fujisawa M, Hirai M.
    STAT3 polymorphism rs4796793 may be a predictive factor of tumor response to multiple tyrosine kinase inhibitors in metastatic renal cell carcinoma in Japanese population.
    Med Oncol, 33(3):24 (2016)
  • Yamamoto K, Shinomiya K, Ioroi T, Hirata S, Harada K, Suno M, Nishioka T, Kume M, Makimoto H, Nakagawa T, Hirano T, Bito T, Nishigori C, Miyake H, Fujisawa M, Hirai M.
    Association of single nucleotide polymorphisms in STAT3 with hand-foot skin reactions in patients with metastatic renal cell carcinoma treated with multiple tyrosine kinase inhibitors: a retrospective analysis in Japanese patients.
    Target Oncol. 11(1):93-9 (2016)


2014年度





2013年度





2012年度





2011年度





2010年度




バナースペース

薬剤学分野

〒650-0017
兵庫県神戸市中央区楠町7丁目5-2
神戸大学医学部附属病院 薬剤部

TEL: 078-382-6659
FAX: 078-382-6676
E-mail: yakuken@med.kobe-u.ac.jp