Division of Molecular Medicine & Medical Genetics, Department of Pathology,
	Kobe University Graduate School of Medicine.
http://www.med.kobe-u.ac.jp/molgene/index.html http://www.med.kobe-u.ac.jp/molgene/index-jp.html
Japanese


Publication List

  • Hayashi Y, Chan J, Nakabayashi H, Hashimoto T, Tamaoki T. Identification and characterization of two enhancers of the human albumin gene (J Biol Chem. 267:14580-14585, 1992)
  • Itoh H, Hanioka K, Obayashi C, Kanomata N, Itoh K, Imai Y, Kuroda N, Hayashi Y. Intrauterine infection: Pathological study on chorioamnionitis and villitis of unknown etiology. [Endocrine J, 41:S135-S140, 1994]
  • Hayashi Y, Widjono YW, Ohta K, Hanioka K, Obayashi C, Itoh K, Itoh H. Expression of EGF, EGF-receptor, p53, v-erb B and ras p21 in colorectal neoplasms by immunostaining paraffin-embedded tissues. (Pathol Int, 44:124-130, 1994)
  • Kim SR, Kang KB, Soh CG, Kim JH, Hayashi Y, Hanioka K, Itoh H. Clinicopathological study of Meidum-Sized Hepatocellular carcinoma -An approach to the definition of early hepatocellular carcinoma-. [J Gastroenterol Hepatol, 10:498-508, 1995]
  • Sugano M, Hayashi Y, Yoon S, Kinoshita M, Ninomiya T, Ohta K, Itoh H, Kasuga M. Quantitation of Hepatitis C Viral RNA in Liver Tissues and Sera by Competitive PCR: Relationship with Response to Interferon Alpha Treatment. [J Clin Pathol, 48:820-825, 1995]
  • Hayashi Y, Hanioka K, Kanomata N, Imai Y, Itoh H. Clinicopathologic and molecular pathologic approaches to Lowe's syndrome. (Pediatr Pathol Lab Med, 15:389-402, 1995)
  • Hayashi Y, Ishii N, Obayashi C, Jinnai K, Hanioka K, Imai Y, Itoh H. Thymoma, its tumorigenesis and progression in relationship with expression of EGF, EGF-Receptor, p53, v-erb and ras p21. (Virchows Archiv, 426:43-50, 1995)
  • Kanazawa K, Kawashima S, Mikami S, Miwa Y, Hirata K, Suematsu M, Hayashi Y, Itoh H, Yokoyama M. Endothelial constitutive nitric oxide synthase protein and mRNA increased in rabbit atherosclerotic aorta despite of impaired endothelium-dependent vascular relaxations. (Am J Pathol, 148:1949-1956, 1996)
  • Ninomiya T, Hayashi Y, Ohta K, Saijoh K, Yoon S, Nakabayashi H, Kasuga M, Itoh H. Expression Ratio of Hepatocyte Nuclear Factor-1 and Its Variant is Linked to Differentiation of Hepatocytic Neoplasms. (J Hepatol, 25:445-453, 1996)
  • Mikami S, Kawashima S, Kanazawa K, Hirata K, Katayama Y, Hotta H, Hayashi Y, Itoh H, Yokoyama M. Expression of nitric oxide synthase in a murine model of viral myocarditis induced by coxsackievirus B3. (Biochem Biophys Res Commun, 220:983-989, 1996)
  • Mikami S, Kawashima S, Kanazawa K, Hirata K, Katayama Y, Hotta H, Hayashi Y, Itoh H, Yokoyama M. Low dose L-NAME treatment improves survival rate and myocardial injury in a murine model of viral myocarditis induced by coxsackievirus B3 (Circulation Res 81:504-511, 1997)
  • Morita Y, Hayashi Y, Suzuki S, Kawasaki K, Ohta K, Kanamaru T, Yamamoto M, Saito Y, Ito H, Wang Y, Doe WF. Expression of Urokinase-type Plasminogen Activator Receptor in Hepatocellular Carcinoma (Hepatol 25:856-861, 1997)
  • Seo Y, Matozaki T, Tsuda M, Hayashi Y, Itoh H, Kasuga M. Overexpression of SAP-1, a human transmembrane-type protein tyrosine phosphatase in colorectal cancers (Biochem Biophys Res Commun 231:705-711, 1997)
  • Ohta K, Kanamaru T, Morita Y, Yamamoto M, Saitoh Y, Hayashi Y, Itoh H. Telomerase Activity in Hepatocellular Carcinoma with the use of Modified TRAP Assay (J Gastroenterol 32:791-796, 1997)
  • Wang W, Hayashi Y, Ohta K, Ninomiya T, Nakabayashi H, Tamaoki T, Itoh H. Expression of HNF-1a and HNF-1b in Various Histological Differentiations of Hepatocellular Carcinoma (J Pathol 184:272-278, 1998)
  • Kawasaki K, Hayashi Y, Nishida Y, Miki A, Itoh, H. Developmental expression of the tight junction protein Occludin in the gastrointestinal tract in the chick embryo (Histochem Cell Biol 109 (1) : 19-24, 1998)
  • Kim SR, Hayashi Y, Yoon S, Taniguchi M, Yang MK, Kim KI, Kim MM, Saeki K, Nukata I, Imoto S. Prediction of efficancy of interferon treatment of chronic hepatitis C by new classification of chronic hepatitis (Pathol International 48:215-220, 1998)
  • Ninomiya T, Yoon S, Hayashi Y, Sugano M, Kumon Y, Seo Y, Shimizu K, Kasuga M. Clinical significance of serum hyaluronic acid as a marker of fibrosis in chronic hepatitis C patients treated with alfa interferon -Histological evaluation using modified HAI system- [J Gastroenterol Hepatol 13:68-74, 1998]
  • Kuroda N, Yoshikawa N, Nakanishi K, Iijima K, Hanioka K, Hayashi Y, Imai Y, Sado Y, Nakayama M, Itoh H.Expression of type IV collagen in the developing human kidney (Pediatric Nephrol 12:554-558, 1998)
  • Kuroda N, Hayashi Y, Matozaki T, Hanioka K, Gotoh A, Wang W, Uchida H, Hashimoto K, Iwai Y, Kawasaki K, Imai Y, Kasuga M, Itoh H. Differential Expression of SHP2, a Protein-Tyrosine Phosphatase with SRC Homology-2 Domains, in Various Types of Renal Tumour (Virchows Archiv 433:323-329, 1998)
  • Kawasaki K, Hayashi Y, Suzuki S, Morita Y, Nakamura T, Narita K, Iwatani K, Yamamoto M, Saitoh Y, Itoh H, Wang Y, Doe WF Expression of urokinase plasminogen activator receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1) in the gastric cancer (J Gastroenterol Hepatol 13(9):892-896, 1998)
  • Suzuki S, Hayashi Y, Morita Y, Kawasaki K, Ohta K, Nakamura T, Nakae S, Saitoh Y, Aoyama N, Yoshida H, Itoh H, Wang Y, Doe WF Expression of receptor for urokinase plasminogen activator in colorectal adnomas and carcinomas (GUT 43(6):798-805, 1998)
  • Noguchi K, Yoshikawa N, Kariya-Ito S, Inoue Y, Hayashi Y, Itoh H Activated mesangial cells produce vascular prmeability factor in early-stage mesangial proliferative glomerulonephritis (J Am Soc Nephrol 9:1815-1825, 1998)
  • Funasaka Y, A.K.Chakraborty AK, Hayashi Y, Komoto M, Ohashi A, Nagahama M, Inoue Y, J.Pawelek J , Ichihashi M Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin-1 [alpha] , interleukin-1 [beta] , endothelin-1 and tumour necrosis factor- [alpha] (Bri J Dermatol 139(2):216-224, 1998)
  • Ninomiya T, Yoon S, MD, Sugano M, Kumon Y, Seo Y, Shimizu K, Nagano H, Kasuga M, Hayashi Y Improvement of The Molar Ratio of Branched-Chain Amino Acids to Tyrosine (BTR) Associated with Liver Fibrosis in Chronic Hepatitis C Patients Treated with Interferon-a (Digestive Diseases and Sciences 44:1027-1033, 1999)
  • Morita Y, Hayashi Y, Kanamaru T, Itoh T, Suzuki S, Yamamoto M, Kuroda Y, Itoh H Inhibitory Role of Plasminogen Activator Inhibitor-1 in Invasion and Proliferation of HLE, Hepatocellular Carcinoma Cells (Jpn J Cancer Res 90:747-752, 1999)
  • Imai Y, Nishijima E, Muraji T, Hashimoto K, Hayashi Y, Itoh H Fusion of intussusceptum and intussuscipiens in intrauterine intussusception: A rare type of intestinal atresia (Pathol International 49:969-967, 1999)
  • Azumi H, Inoue N, Takeshita S, Rikitake Y, Kawashima S, Hayashi Y, Itoh H, Yokoyama M Expression of NADH/NADPH Oxidase p22phox in human coronary artery (Circulation 100:1494-1498, 1999)
  • Fukunaga K, Matozaki T, Hayashi Y, Fujioka Y, Tsuda M, Takada T, Noguchi T, Kasuga M, Itoh H. The distribution and characterization of SHPS-1, that binds protein tyrosine phosphatase SHP-2, in the human and rat brain (Biomedical Research 20:197-203, 1999)
  • Kim SR, Hayashi Y, Kudo M, Imoto S, Song KB, Ando K, Shintani S, Koterazawa T, Kim KI, Taniguchi M. TTV positivity and transfusion history in non-B and non-C HCC compared with HBV- and HCV- positive cases (Intervirology 43:13-15, 2000)
  • Fukunaga K, Noguchi T, Takeda H, Matozaki T, Hayashi Y, Itoh H, Kasuga M. Requirement for protein tyrosine phosphatase SHP-2 in insulin-induced activation of c-jun NH3-terminal kinase (J Biol Chem 275:5208-5213, 2000)
  • Karim MM, Hayashi Y, Inoue M, Imai Y, Itoh H. Cox-2 expression in retinoblastoma (Am J Ophthalmology 129:398-401, 2000)
  • Miwa M, Saura R, Hirata S, Hayashi Y, Mizuno K, Itoh H. Induction of apoptosis in bovine articular chondrocyte by prostaglandin E-2 through cAMP-dependent pathway. (Osteoarthritis Cartilage 8: 17-24, 2000)
  • Zhou L, Hayashi Y, Itoh T, Wang W, Rui JA, Itoh H. Expression of Urokinase-Type Plasminogen Activator, Urokinase-Type Plasminogen Activator Receptor, Plasminogen Activator Inhibitor-1 and -2 in Hepatocellular Carcinoma (Pathology International 50:392-397, 2000)
  • Itoh T, Hayashi Y, Kanamaru T, Morita Y, Suzuki S, Wang W, Zhou L, Rui JA,Yamamoto M, Kuroda Y, Itoh H. Clinical Significance of Urokinase-type Plasminogen Activator Activity in Hepatocellular Carcinoma (J Gastroenterol Hepatol 15:422-430, 2000)
  • Wong N, Lai P, Pang E, Fung LF, Sheng Z, Wong V, Wang WP, Hayashi Y, Perlman E, Yuna S, Lau JWY, Johnson PJ. Genomic aberrations in human hepatocellular carcinomas of differing etiologies (Clinical Cancer Res 6: 4000-4009, 2000)
  • Ozaki M, Kawashima S, Yamashita T, Ohashi Y, Rikitake Y, Inoue N, Hirata K, Hayashi Y, Itoh H. Endothelial nitric oxide synthase overexpression prevents pulmonary hypertension and reduces pulmonary vascular remodeling in mice exposed to chronic hypoxia. (Hypertension 37:322-327, 2001)
  • Kawashima S, Yamashita T, Ozaki M, Ohashi Y, Azumi H, Inoue N, Hirata K, Hayashi Y, Itoh H Endothelial nitric oxide synthase-overexpression prevents vascular remodeling with neointima formation in the carotid artery of mice (Atheroscler thromb Vasc Biol 21:201-207,2001)
  • Ninomiya T, Yoon S, Nagano H, Kumon Y, Seo Y, Kasuga M, Yano Y, Nakaji M, Hayashi Y, Significance of serum matrix metalloproteinases and their inhibitors on the antifibrogenetic effect of interferon alfa in chronic hepatitis C patients (Intervirology 44:227-31,2001)
  • Okuda M, Inoue N, Azumi H, Seno T, Sumi Y, Hirata K, Kawashima S, Hayashi Y, Itoh H, Yodoi J, Yokoyama M. Expression of Glutaredoxin in human coronary arteries its potential role in antioxidant protection in atherosclerosis (Arterioscler Thromb Vasc Biol 21:1483-7, 2001)
  • Ikawa H, Hayashi Y, Ninomiya T, Yano Y, Nakaji M, Nagano H, Seo Y, Kumon Y, Yoon S, Kasuga M, Itoh H.Various scoring systems evaluating histological features of chronic hepatitis C after IFN therapy (Hum Pathol 32:910-917,2001)
  • Miskad UA, Yano Y, Kishi S, Nakaji M, Hayashi Y. Histological study of PIVKA-II expression in small-sized hepatocellular carcinoma and adenomatous hyperplasia (Pathology International 51:916-922, 2001)
  • Tatsumi E. A mini-review of CD13 antigen in AML: easy induction or enhancement of expression in in vitro culture and necessary consideration for assessment. (Southeast Asian J Trop Med Public Health. 33 Suppl 2:155-157,2002)
  • Sumi Y, Inoue N, Azumi H, Seno T, Okuda M, Hirata K, Kawashima S, Hayashi Y, Itoh H, Yokoyama M. Expression of tissue transglutaminase and elafin in human coronary artery Implication for plaque instability (Atherosclerosis 160:31-39, 2002)
  • Ninomiya T, Mihara K, Fushimi K, Hayashi Y, Hashimoto-Tamaoki T, Tamaoki T. Regulation of the alpha-fetoprotein gene by the isoforms of ATBF1 transcription factor in human hepatoma (Hepatol 35:82-87, 2002)
  • Yamao T, Noguchi T, Takeuchi O, Nishiyama U, Morita H, Hagiwara T, Akahori H, Kato T, Inagaki K, Okazawa H, Hayashi Y, Matozaki T, Takeda K, Akira S, Kasuga M. Negative regulation of platelet clearance and of macrophage phagocytic response by the transmembrane glycoprotein SHPS-1. (J Biol Chem 277:39833-39839, 2002)
  • Hayashi T, Tsujino T, Iwata S, Nonaka H, Emoto N, Yano Y, Otani S, Hayashi Y, Itoh H, Yokoyama M. Decreased ornithine decarboxylase activity in the kidneys of Dahl salt-sensitive rats. (Hypertens Res. 2002 Sep;25(5):787-95)
  • Azumi H, Inoue N, Ohashi Y, Terashima M, Mori T, Fujita H, Awano K, Kobayashi K, Maeda K, Hata K, Shinke T, Kobayashi S, Hirata K, Kawashima S, Itabe H, Hayashi Y, Imajoh-Ohmi S, Itoh H, Yokoyama M. Superoxide generation in directional coronary atherectomy specimens of patients with angina pectoris: important role of NAD(P)H oxidase. (Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1838-44)
  • Kitamura H, Ohnishi Y, Yoshida A, Okajima K, Azumi H, Ishida A, Galeano EJ, Kubo S, Hayashi Y, Itoh H, Yokoyama M. Heterogeneous loss of connexin43 protein in nonischemic dilated cardiomyopathy with ventricular tachycardia. (J Cardiovasc Electrophysiol. 2002 Sep;13(9):865-70)
  • Kobayashi S, Inoue N, Azumi H, Seno T, Hirata K, Kawashima S, Hayashi Y, Itoh H, Yokozaki H, Yokoyama M.Expressional changes of the vascular antioxidant system in atherosclerotic coronary arteries. (J Atheroscler Thromb. 2002;9(4):184-90)
  • Nakaji M, Hayashi Y, Ninomiya T, Yoon S, Seo Y, Nagano H, Komori H, Hashimoto K, Orino A, Shirane H, Yokozaki H. Histological grading and staging in chornic hepatitis: Its practical correlation. (Pathology International 52:683-690, 2002)
  • Kim SR, Imoto S, Maekawa Y, Matsuoka T, Hayashi Y, Ando K, Mita K, Shintani S, Kim HB, Ku K, Koterazawa T, Fukuda K, Yano Y, Nakaji M, Ikawa H, Ninomiya T, Kudo M, Kim KI, Hirai M. CEA producing primary hepatic carcinoid. (Hepatol Res 22:313-321, 2002)
  • Kim S, Maekawa Y, Matsuoka T, Imoto S, Ando K, Mita K, Kim H, Nakajima T, Ku K, Koterazawa T, Fukuda K, Yano Y, Nakaji M, Kudo M, Kim K, Hirai M, Hayashi y. Eosinophilic pseudotumor of the liver due top Ascaria suum infection. (Hepatol Res 23:306, 2002)
  • Kim SR, Matsuoka T, Maekawa Y, Yano Y, Imoto S, Kudo M, Shintani S, Ando K, Mita K, Fukuda K, Koterazawa T, Nakaji M, Ikawa H, Ninomiya T, Kim KI, Hirai M, Hayashi Y. Development of multicentric hepatocellular carcinoma after completion of interferon therapy. (J Gasteroenterol 37:663-668, 2002)
  • Seo Y, Yoon S, Nakaji M, Yano Y, Nagano H, Ninomiya T, Hayashi Y, Kasuga M. Hepatitis B Virus DNA in Anti-HBe-Positive Asymptomatic Carriers.(Intervirology. 46(1):43-9, 2003)
  • Seki S, Kitada T, Sakaguchi H, Iwai S, Kawada N, Hayashi Y, Kim SR. Expression of progenitor cell markers in livers with fulminant massive necrosis. (Hepatology Research 25:149-157, 2003)
  • Yano Y, Hayashi Y, Nakaji M, Nagano H, Seo Y, Ninomiya T, Yoon S, Wada A, Hirai M, Kim SR, Yokozaki H, Kasuga M. Different apoptotic regulation of TRAIL-caspase pathway in HBV- and HCV-related hepatocellular carcinoma. (Int J Mol Med 11:499-504, 2003)
  • Nagano H, Noguchi T, Inagaki K, Yoon S, Matozaki T, Itoh H, Kasuga M, Hayashi Y, Down-regulation of stomach cancer|associated protein tyrosine phosphatase|1 (SAP-1) in advanced human hepatocellular carcinoma (Oncogene 22:46564663, 2003)
  • Kobayashi S, Inoue N, Ohashi Y, Terashima M, , Matsui K, Mori T, Fujita H, Awano K, Kobayashi K, Azumi H, Ejiri J, Hirata K, Kawashima S, Hayashi Y, Yokozaki H, Itoh H, Yokoyama M. Interaction of oxidative stress and inflammatory response in coronary plaque instability . (J Atheroscler Thromb. 23:1398-1404, 2003)
  • Matsumoto M, Ogawa W, Akimoto K, Inoue H, Miyake K, Furukawa K, Hayashi Y, Iguchi H, Matsuki Y, Hiramatsu R, Shimano H, Yamada N, Ohno S, Kasuga M, Noda T. Protein kinase Cl in liver mediates insulin-induced SREBP-1c expression and determine both hepatic lipid content and overall insulin sensitivity. (J Clin Investigation 112:935-944, 2003)
  • Yano Y, Hayashi Y, Sano K, Shinmaru H, Kuroda Y, Yokozaki H, Yoon S, Kasuga M. Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I|3 (E-NPP3/CD203c/PD-Ib/B10/gp130RB13-6) in human colon carcinoma. (Int J Mol Med 12(5):763-766, 2003)
  • Gomyo H, Shimoyama M, Minagawa K, Yakushijin K, Urahama N, Okamura A, Yamamoto K, Ito M, Chihara K, Hayashi Y, Matsui T. Morphologic, flow cytometric and cytogenetic evaluation of bone marrow involvement in B-cell lymphoma. (Haematologica 88(12):1358-65, 2003)
  • Ejiri J, Inoue N, Tsukube T, Munezane T, Hino Y, Kobayashi S, Hirata K, Kawashima S, Imajoh-Ohmi S, Hayashi Y, Yokozaki H, Okita Y, Yokoyama M. Oxidative stress in the pathogenesis of thoracic aortic aneurysm: protective role of statin and angiotensin II type 1 receptor blocker. (Cardiovasc Res. 59(4):988-996, 2003)
  • Azumi H, Hirata K, Ishida T, Kojima Y, Rikitake Y, Takeuchi S, Inoue N, Kawashima S, Hayashi Y, Itoh H, Quertermous T, Yokoyama M. Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries. (Cardiovasc Res. 58(3):647-654, 2003)
  • Hardianti MS, Tatsumi E, Syampurnawati M, Furuta K, Saigo K, Kawano S, Kumagai S, Nakamura F, Matsuo Y. Expression of activation-induced cytidine deaminase (AID) in Burkitt lymphoma cells: rare AID-negative cell lines with the unmutated rearranged VH gene. (Leuk Lymphoma. 2004 45(1):155-160, 2004)
  • Takenokuchi M, Yasuda C, Takeuchi K, Nakamachi Y, Mukai M, Kondo S, Kumagai S, Saigo K, Murayama T, Koizumi T, Tatsumi E. Quantitative nested reverse transcriptase PCR vs. real-time PCR for measuring AML1/ETO (MTG8) transcripts. (Clin Lab Haematol. 26(2):107-114, 2004)
  • Hardianti MS, Tatsumi E, Syampurnawati M, Furuta K, Saigo K, Nakamachi Y, Kumagai S, Ohno H, Tanabe S, Uchida M, Yasuda N. Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL. (Leukemia. 18(4):826-831, 2004)
  • Nakaji M, Yano Y, Ninomiya T, Seo Y, Hamano K, Yoon S, Kasuga M, Teramoto T, Hayashi Y, Yokozaki H. IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat. (Carcinogenesis 25(3):389-397, 2004)
  • Seo Y, Yoon S, Hamano K, Nakaji M, Yano Y, Katayama M, Ninomiya T, Hayashi Y, Kasuga M. Early response to interferon alpha treatment and long-term clinical outcome in Japanese patients with chronic HBV genotype C infection. (Int J Mol Med. 13(1):75-79, 2004)
  • Yano Y, Hayashi Y, Sano K, Nagano H, Nakaji M, Seo Y, Ninomiya T, Yoon S, Yokozaki H, Kasuga M. Expression and localization of ecto-nucleotide pyrophosphatase /phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases. (Cancer Lett 207(2):139-47, 2004)
  • Seo Y, Yoon S, Hamano K, Nakaji M, Yano Y, Katayama M, Ninomiya T, Hayashi Y, Kasuga M. Response to interferon-alpha in chronic hepatitis B with and without Precore mutant strain detected by mutation site-specific assay. (J Clin Gastroenterol 38(5):460-464, 2004)
  • Yano Y, Hayashi Y, Teramoto T, Nakaji M, Nagy P, Ninomiya T, Wada A, Hirai M, Kim SR, Seo Y, Yoon S, Kasuga M. Apoptotic pathway related to oval cell proliferation. (J Gastroenterol Hepatol19(8):866-872, 2004)
  • Maniwa Y, Yoshimura M, Bermudez VP, Yuki T, Okada K, Kanomata N, Ohbayashi C, Hayashi Y, Hurwitz J, Okita Y. Accumulation of hRad9 protein in the nuclei of nonsmall cell lung carcinoma cells. (Cancer 103(1):126-132, 2005)
  • Uchida T, Nakamura T, Hashimoto N, Matsuda T, Kotani K, Sakaue H, Kido Y, Hayashi Y, Nakayama KI, White MF, Kasuga M. Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice. (Nature Medicine 11(2):175 - 182, 2005)
  • Kim KI, Sasase N, Taniguchi M, Mita K, Kim SR, Tanaka K, Hayashi Y. Prediction of efficacy of interferon treatment of chronic hepatitis C and occurrence of HCC after interferon treatment by a new classification. (Intervirology 48(1):52-58, 2005)
  • Kim SR, Imoto S, Taniguchi M, Kim KI, Sasase N, Matsuoka T, Maekawa Y, Ninomiya T, Ando K, Mita K, Fuki S, Koterazawa T, Fukuda K, Kudo M, Sakamoto H, Hayashi Y. Primary sclerosing cholangitis and hepatitis C virus infection. (Intervirology 48(4):268-272, 2005))
  • Kim SR, Maekawa Y, Ninomiya T, Imoto S, Matsuoka T, Ando K. , Mita K, Ku K, Koterazawa T, Nakajima T, Fukuda K, Yano Y, Nakaji M, Kudo M, Kim KI, Hirai M, Hayashi Y. Multiple hypervascular liver nodules in a heavy drinker of alcohol (J Gastroenterol Hepatol 20(5):795-799,2005)
  • Seo Y, Yoon S, Kato H, Hamano K, Yano Y, Katayama M, Ninomiya T, Hayashi Y, Kasuga M. Serum hepatitis B virus DNA levels differentiating inactive carriers from patients with chronic hepatitis B. (Eur J Gasteroenterol Hepatol 17(7):753-757, 2005)
  • Kim KI, Sasase N, Taniguchi M, Mita K, Kinoshita K, Togitani T, Shikata M, Kimura N, Izawa S, Ohtani A, Nakao K, Muramoto Y, Kim SR, Nabeshima S, Ishii F, Tanaka K, Hayashi Y. Interferon-beta induction/interferon-alpha2b plus ribavirin therapy in patients with chronic hepatitis C. (Int J Clin Pharmacol Res 25(2):71-76, 2005)
  • Truong BX, Seo Y, Kato M, Hamano K, Ninomiya T, Katayama M, Kato H, Yano Y, Hayashi Y, Kasuga M. Long-term follow-up of Japanese patients with chronic hepatitis B treated with interferon-alpha.(Int J Mol Med 16(2):279-284, 2005)
  • Yamaguchi M, Sugimoto K, Zamora CA, Takahashi T, Hayashi Y, Sugimura K. Placement of Self-expanding Stents with Different Diameters in the Porcine Venous System: An Experimental Study (J Vasc Interv Radiol. 17(1):113-119, 2006)
  • Ejima Y, Sasaki R, Okamoto Y, Maruta T, Azumi A, Hayashi Y, Demizu Y, Ota Y, Soejima T, Sugimura K. Ocular adnexal mucosa-associated lymphoid tissue lymphoma treated with radiotherapy. (Radiother Oncol. 78(1):6-9, 2006)
  • Yamaguchi M, Sugimoto K, Zamora CA, Takahashi T, Hayashi Y, Sugimura K. Placement of Self-expanding Stents with Different Diameters in the Porcine Venous System: An Experimental Study (J Vasc Interv Radiol. 17(1):113-119, 2006)
  • Maniwa Y, Yoshimura M, Bermudez VP, Okada K, Kanomata N, Ohbayashi C, Nishimura Y, Hayashi Y, Hurwitz J, Okita Y. His239Arg SNP of HRAD9 is associated with lung adenocarcinoma. (Cancer. 106(5):1117-1122, 2006)
  • Sakuma T, Hayashi Y, Kanomata N, Murayama T, Matsui T, Kajimoto K, Hanioka K, Chihara K, Maeda S. Histological and cytogenetic characterization of bone marrow in relation to prognosis and diagnosis of myelodysplastic syndromes. (Pathol Int. 56(4):191-199, 2006)
  • Tsuji G, Koshiba M, Nakamura H, Kosaka H, Hatachi S, Kurimoto C, Kurosaka M, Hayashi Y, Yodoi J, Kumagai S. Thioredoxin protects against joint destruction in a murine arthritis model. (Free Radic Biol Med. 40(10):1721-1731, 2006)
  • Syampurnawati M, Tatsumi E, Furuta K, Hayashi Y. Four novel point mutations in exons 12, 13, and 14 of the FLT3 gene. (Leuk Res. 2006 Aug 30; [Epub ahead of print])
  • Nakae J Cao Y, Daitoku H, Fukamizu A, Ogawa W Yano Y, Hayashi Y. The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity. (J Clin Investigation 116(9):2473-83, 2006)
  • Nakayama S, Kanbara Y, Nishimura T, Nishida N, Hanioka K, Morita M, Fujita M, Sakurai K, Hayashi y. Genome-wide microsatellite analysis of focal nodular hyperplasia: a strong tool for the differential diagnosis of non-neoplastic liver nodule from hepatocellular carcinoma.Genome-wide microsatellite analysis of focal nodular hyperplasia: a strong tool for the differential diagnosis of non-neoplastic liver nodule from hepatocellular carcinoma. (J Hepatobiliary Pancreat Surg. 13(5):416-420, 2006)
  • Syampurnawati M, Tatsumi E, Furuta K, Takenokuchi M, Nakamachi Y, Kawano S, Kumagai S, Saigo K, Matsui T, Takahashi T, Nagai KI, Yabe H, Kondo S, Hayashi Y. HLA-DR-negative AML (M1 and M2): FLT3 mutations (ITD and D835) and cell-surface antigen expression. (Leuk Res. 2006 Oct 20; [Epub ahead of print])
  • Haraguchi T, Okada K, Tabata Y, Maniwa Y, Hayashi Y, Okita Y. Controlled release of basic fibroblast growth factor from gelatin hydrogel sheet improves structural and physiological properties of vein graft in rat. (Arterioscler Thromb Vasc Biol. 27(3):548-555, 2007)
  • Truong BX, Seo Y, Yano Y, Ho PT, Phuong TM, Long DV, Son NT, Long NC, Kato H, Hayashi Y, Trach NK, Kasuga M. Genotype and variations in core promoter and pre-core regions are related to progression of disease in HBV-infected patients from Northern Vietnam. (Int J Mol Med. 19(2):293-299, 2007)
  • Utsumi T, Yano Y, Truong BX, Tanaka Y, Mizokami M, Seo Y, Kasuga M, Kawabata M, Hayashi Y. Molecular epidemiological study of hepatitis B virus infection in two different ethnic populations from the Solomon Islands. (J Med Virol. 79(3):229-235, 2007)
  • Takahashi Y, Iida K, Takahashi K, Yoshioka S, Fukuoka H, Takeno R, Imanaka M, Nishizawa H, Takahashi M, Seo Y, Hayashi Y, Kondo T, Okimura Y, Kaji H, Kitazawa R, Kitazawa S, Chihara K. Growth hormone reverses nonalcoholic steatohepatitis in a patient with adult growth hormone deficiency. (Gastroenterology 132(3):938-943, 2007)
  • Truong BX, Yano Y, Seo Y, Phuong TM, Tanaka Y, Kato H, Miki A, Utsumi T, Azuma T, Trach NK, Mizokami M, Hayashi Y, Kasuga M.. Variations in the core promoter/pre-core region in HBV genotype C in Japanese and Northern Vietnamese patients. (J Med Virol 79(9):1293-1304, 2007)
  • Takata M, Maniwa Y, Doi T, Tanaka Y, Okada K, Nishio W, Ohbayashi C, Yoshimura M, Hayashi Y, Okita Y. Double-layered collagen gel hemisphere for cell invasion assay: successful visualization and quantification of cell invasion activity. (Cell Commun Adhes 14(4):157-167, 2007)
  • Nakae J, Cao Y, Oki M, Orba Y, Sawa H, Kiyonari H, Iskandar K, Suga K, Lombes M, Hayashi Y. Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure. (Diabetes 57(3):563-576, 2008)
  • Syampurnawati M, Tatsumi E, Ardianto B, Takenokuchi M, Nakamachi Y, Kawano S, Kumagai SI, Saigo K, Matsui T, Takahashi T, Nagai KI, Gunadi , Nishio H, Yabe H, Kondo SI, Hayashi Y. DR negativity is a distinctive feature of M1/M2 AML cases with NPM1 mutation. (Leuk Res. 2008 Jan 2; [Epub ahead of print] )
  • Miki A, Yano Y, Kato H, Seo Y, Kuriyama M, Azuma T, Hayashi Y. Anti-tumor effect of pegylated interferon in the rat hepatocarcinogenesis model. (Int J Oncol. 32(3):603-608, 2008)
  • Taniguchi M, Kim SR, Imoto S, Ikawa H, Ando K, Mita K, Fuki S, Sasase N, Matsuoka T, Kudo M, Hayashi Y. Long-term outcome of percutaneous ethanol injection therapy for minimum-sized hepatocellular carcinoma.(World J Gastroenterol. 2008 Apr 7;14(13):1997-2002)
  • Sasase N, Kim SR, Kim KI, Taniguchi M, Imoto S, Mita K, Hotta H, Shouji I, El-Shamy A, Kawada N, Kudo M, Hayashi Y. Usefulness of a new immunoradiometric assay of HCV core antigen to predict virological response during PEG-IFN/RBV combination therapy for chronic hepatitis with high viral load of serum HCV RNA genotype 1b. (Intervirology. 2008;51 Suppl 1:70-5)
  • Yuki T, Maniwa Y, Doi T, Okada K, Nishio W, Hayashi Y, Okita Y.DNA damage sensor protein hRad9, a novel molecular target for lung cancer treatment. (Oncol Rep. 2008 Nov;20(5):1047-52)
  • Sun L, Ishida T, Yasuda T, Kojima Y, Honjo T, Yamamoto Y, Yamamoto H, Ishibashi S, Hirata K, Hayashi Y. RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice. (Cardiovasc Res. 2009 May 1;82(2):371-81)
  • Taniguchi M, Kim SR, Mishiro S, Takahashi K, Shin MH, Yun H, Park MS, Li ZM, Kim MK, Fang J, Hayashi Y. Epidemiology of hepatitis E in Northeastern China, South Korea and Japan. (J Infect. 2009 Mar;58(3):232-7)
  • Nakagawa T, Tanaka H, Shirakawa T, Gotoh A, Hayashi Y, Hamada K, Tsukuda M, Nibu K. Cyclooxygenase 2 promoter-based replication-selective adenoviral vector for hypopharyngeal cancer. (Arch Otolaryngol Head Neck Surg. 2009 Mar;135(3):282-6)
  • Utsumi T, Lusida MI, Yano Y, Nugrahaputra VE, Amin M, Juniastuti, Soetjipto, Hayashi Y, Hotta H. Complete Genome Sequence and Phylogenetic Relatedness of Hepatitis B Virus Isolates in Papua, Indonesia.(J Clin Microbiol. 2009 Jun;47(6):1842-7.)
  • Youssef A, Yano Y, Utsumi T, abd El-alah EM, abd El-Hameed Ael-E, Serwah Ael-H, Hayashi Y. Molecular epidemiological study of hepatitis viruses in Ismailia, Egypt. (Intervirology. 2009;52(3):123-31)
  • Maekawa T, Maniwa Y, Doi T, Nishio W, Yoshimura M, Ohbayashi C, Hayashi Y, Okita Y. Expression and localization of FOXO1 in non-small cell lung cancer. (Oncol Rep. 2009 Jul;22(1):57-64.)
  • Yanagi D, de Vries GC, Rahardjo D, Alimsardjono L, Wasito EB, De I, Kinoshita S, Hayashi Y, Hotta H, Osawa R, Kawabata M, Shirakawa T. Emergence of fluoroquinolone-resistant strains of Salmonella enterica in Surabaya, Indonesia. ( Diagn Microbiol Infect Dis. 2009 Aug;64(4):422-6.)
  • Yoshida K, Sasaki R, Nishimura H, Okamoto Y, Suzuki Y, Kawabe T, Saito M, Otsuki N, Hayashi Y, Soejima T, Nibu K, Sugimura K. Nuclear factor-kappaB expression as a novel marker of radioresistance in early-stage laryngeal cancer. (Head Neck. 2010 May;32(5):646-55.)
  • Tanaka Y, Maniwa Y, Bermudez VP, Doi T, Nishio W, Ohbayashi C, Okita Y, Hurwitz J, Hayashi Y, Yoshimura M. Nonsynonymous single nucleotide polymorphisms in DNA damage repair pathways and lung cancer risk. (Cancer. 2010 Feb 15;116(4):896-902.)
  • Sasase N, Kim SR, Kudo M, Kim KI, Taniguchi M, Imoto S, Mita K, Hayashi Y, Shoji I, El-Shamy A, Hotta H. Outcome and early viral dynamics with viral mutation in PEG-IFN/RBV therapy for chronic hepatitis in patients with high viral loads of serum HCV RNA genotype 1b. (Intervirology. 2010;53(1):49-54. Epub 2010 Jan 5.)
  • Iskandar K, Cao Y, Hayashi Y, Nakata M, Takano E, Yada T, Zhang C, Ogawa W, Oki M, Chua S Jr, Itoh H, Noda T, Kasuga M, Nakae J. PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake. (Am J Physiol Endocrinol Metab. 2010 Apr;298(4):E787-98.)
  • Cangara HM, Ishida T, Hara T, Sun L, Toh R, Rikitake Y, Kundu RK, Quertermous T, Hirata K, Hayashi Y. Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis. (Microvasc Res. 2010 Jul;80(1):133-41.)
  • Kimura R, Ishida T, Kuriyama M, Hirata K, Hayashi Y. Interaction of endothelial cell-selective adhesion molecule and MAGI-1 promotes mature cell-cell adhesion via activation of RhoA. (Genes Cells. 2010 Apr 1;15(4):385-96.)
  • Nakai R, Maniwa Y, Tanaka Y, Nishio W, Yoshimura M, Okita Y, Ohbayashi C, Satoh N, Ogita H, Takai Y, Hayashi Y. Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma. (Cancer Sci. 2010 May;101(5):1326-30.)
  • Kinoshita H, Hori Y, Fukumoto T, Ohigashi T, Shinohara K, Hayashi Y, Ku Y. Novel assessment of hepatic iron distribution by synchrotron radiation X-ray fluorescence microscopy. (Med Mol Morphol. 2010 Mar;43(1):19-25.)
  • Chang O, Yano Y, Masuzawa A, Fukushima N, Teramura K, Hayashi Y. The cytological characteristics of small cell change of dysplasia in small hepatic nodules. (Oncol Rep. 2010 May;23(5):1229-32.)
  • Utsumi T, Yano Y, Lusida MI, Amin M, Soetjipto, Hotta H, Hayashi Y. Serologic and molecular characteristics of hepatitis B virus among school children in East Java, Indonesia. (Am J Trop Med Hyg. 2010 Jul;83(1):189-93.)
  • Mita K, Kim SR, Kudo M, Imoto S, Nakajima T, Ando K, Fukuda K, Matsuoka T, Maekawa Y, Hayashi Y. Diagnostic sensitivity of imaging modalities for hepatocellular carcinoma smaller than 2 cm. (World J Gastroenterol. 2010 Sep 7;16(33):4187-92.)
  • Doi T, Maniwa Y, Tanaka Y, Tane S, Hashimoto S, Ohno Y, Nishio W, Nishimura Y, Ohbayashi C, Okita Y, Hayashi Y, Yoshimura M. MT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell. (Exp Mol Pathol. 2011 Feb;90(1):91-6.)
  • Ardianto B, Sugimoto T, Kawano S, Kasagi S, Jauharoh SN, Kurimoto C, Tatsumi E, Morikawa K, Kumagai S, Hayashi Y. The HPB-AML-I cell line possesses the properties of mesenchymal stem cells. (J Exp Clin Cancer Res. 2010 Dec 13;29:163.)
  • Juniastuti, Utsumi T, Nugrahaputra VE, Amin M; Soetjipto, Hayashi Y, Hotta H, Another novel subgenotype of hepatitis B virus genotype C from papuans of Highland origin.Lusida MI. (J Med Virol. 2011 Feb;83(2):225-34.)
  • Utsumi T, Hayashi Y, Lusida MI, Amin M, Soetjipto, Hendra A, Soetjiningsih, Yano Y, Hotta H. Prevalence of hepatitis E virus among swine and humans in two different ethnic communities in Indonesia. (Arch Virol. 2011 Apr;156(4):689-93.)
  • Nishibori T, de Vries GC, Rahardjo D, Wasito EB, De I, Kinoshita S, Hayashi Y, Hotta H, Kawabata M, Shirakawa T, Iijima Y, Osawa R. Phenotypic and genotypic characterization of Vibrio cholerae clinically isolated in Surabaya, Indonesia. (Jpn J Infect Dis. 2011;64(1):7-12.)
  • Satoh N, Maniwa Y, Bermudez VP, Nishimura K, Nishio W, Yoshimura M, Okita Y, Ohbayashi C, Hurwitz J, Hayashi Y. Oncogenic phosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival.(Cancer Sci. 2011 May;102(5):1101-6.)
  • Utsumi T, Yano Y, Truong BX, Kawabata M, Hayashi Y. Characteristics of occult hepatitis B virus infection in the Solomon Islands. (Int J Mol Med. 2011 Jun;27(6):829-34.)
  • Cao Y, Nakata M, Okamoto S, Takano E, Yada T, Minokoshi Y, Hirata Y, Nakajima K, Iskandar K, Hayashi Y, Ogawa W, Barsh GS, Hosoda H, Kangawa K, Itoh H, Noda T, Kasuga M, Nakae J. PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure. (PLoS One. 2011;6(4):e18324.)
  • Yamamoto K, Matsuoka H, Yakushijin K, Funakoshi Y, Okamura A, Hayashi Y, Minami H. A novel five-way translocation, t(3;9;13;8;14)(q27;p13;q32;q24;q32), with concurrent MYC and BCL6 rearrangements in a primary bone marrow B-cell lymphoma. (Cancer Genet. 2011 Sep;204(9):501-6.)


Case Reports

  • Murayama T, Matsui T, Hayashi Y, Taniguchi M, Ito M, Nakazuka T, Imoto S, Isobe T, Itoh H, Chihara K. Plasma cell leukemic with myelofibrosis. (Ann Hematol, 69:151-152, 1994)
  • Uriuhara A, Morita S, Kuroda S, Fumoto M, Araki S, Aoyama N, Amano K, Hayashi Y, Yokono K, Kasuga M. Severe insulin-resistant diabetes mellitus associated with hypereosinophilic syndrome. (Internal Medicine, 632:636,1994)
  • Imoto S, Hayashi Y, Murayama T, Matsui T, Itoh M, Chihara K. Refractory thrombocytopenia with chromosome 11q23 abnormality. (Ann Hematol, 73:99-102, 1996)
  • Murayama T, Imoto S, Matsuoka H, Iwata N, Taniguchi T, Ito M, Chihara K, Matsui T, Hayashi Y, Obayashi C. Acute megaryo monocytic leukemia with acute myelofibrosis (Am J Hematol (letter) 53(2):147-148, 1996)
  • Kim SR, Hayashi Y, Kang KB, Soe CG, Kim JH, Yang MK, Itoh H. A case of psuedolymphoma of the liver with chronic hepatitis C Liver psuedolymphoma with chronic hepatitis C. (J Hepatol 26:209-214, 1997)
  • Kim SR, Hayashi Y, Matsuoka T, Park SY, Shintani S, Sasaki K, Asano J, Kim JH, Kim KI, Imoto S, Itoh H. A case of well-differentiated minute hepatocellular carcinoma with extrahepatic metastasis. (J Gastroenterol Hepatol 13:892-896, 1998)
  • Kuroda N, Hayashi Y, Itoh H. A case of chromophobe renal cell carcinoma with sarcomatoid foci and a small daughter lesion. (Pathol International 48:812-817, 1998)
  • Kuroda N, Hayashi Y, Nishida Y, Itoh H. Combined small and transitional cell carcinoma of the urinary bladder with CA19-9 production. (Pathol International 49:462-467, 1999)
  • Hayashi Y, Hirota S, Yoshikawa T, Ikawa1 H, Itoh H. Epithelioid hemangioendothelioma with marked liver deformity and secondary Budd-Chiari syndrome -pathological and radiological correlation (Pathol International 49:547-552, 1999)
  • Kim SR, Hayashi Y, Kudo M, Matsuoka T, Imoto S, Sasaki K, Shintani S, Song KB, Park SY, Kim JH, Kim KI, Ninomiya T. A case of inflammatory pseudotumour of the liver in patient with chronic hepatitis C-Difficulty in differentiating it from HCC on imaging features-. (Pathol International 49:726-730, 1999)
  • Yamamoto T, Marui T, Mizuno K, Kizaki T, Minami R, Hanioka K, MInami R, Hayashi Y. Anaplastic osteosarcoma with abundant eosinophilic cytoplasm and minimal osteoid production. (Pathology International 50:553-557, 2000)
  • Yamamoto T, Matsushita T, Marui T, Mizuno K, Minami R, Hayashi Y, Hanioka K. Dedifferentiated liposarcoma with chondroblastic osteosarcomatous dedifferentiation. (Pathology International 50:558-561, 2000)
  • Kim SR, Hayashi Y, Kudo M, Matsumoto T, Imoto S, Song KB, Maekawa Y. A case of hepatocellular carcinoma transforming from dysplastic nodule with background of non-B non-C chronic persistent hepatitis. (J Hepatol 33: 857-858, 2000)
  • Murayama T, Hayashi Y, Imoto S, Shimoyama M, Matsuoka H, Nagata A, Iwata N, Taniguchi T, Ito M, Ito H, Chikara K, Matsui T. Massive bone marrow necrosis with polyclonal hypergammaglobulinemia and blue toe syndrome. (Hematol 5:163-165, 2000)
  • Yamamoto T, Marui T, Mizuno K, Obayashi C, Minami R, Inaba M, Hayashi Y. Parosteal fasciitis of the clavicle. (Pathology International 50:987-991, 2000)
  • Ikawa H, Hayashi Y, Obayashi C, Tankawa H, Itoh H. A case of pneumocystis carinii and cytomegalovirus pneumonia in a patient with alcoholic hepatitis with cirrhosis, treated by antibiotics and corticosteroid. (Pathol Int 51:629-32,2001)
  • Kim SR, Matsuoka T, Maekawa Y, Yano Y, Hayashi Y, Kudo M, Kim K, Imoto S, Song KB, Ando K, Shintani S, Koterazawa T, Fukuda K, Mita K, Taniguchi M. A case of disseminated extrahepatic carcinoma after US-guided biopsy and percutaneous ethanol inhjection therapy. (Hepatol Res 20:244-254, 2001)
  • Kim SR, Imoto S, Maekawa Y, Matsuoka T, Hayashi Y, Ando K, Mita K, Shintani S, Kim HB, Ku K, Koterazawa T, Fukuda K, Yano Y, Nakaji M, Ikawa H, Ninomiya T, Kudo M, Kim KI, Hirai M. CEA producing primary hepatic carcinoid. (Hepatol Res 22:313-321, 2002)
  • Kim S, Maekawa Y, Matsuoka T, Imoto S, Ando K, Mita K, Kim H, Nakajima T, Ku K, Koterazawa T, Fukuda K, Yano Y, Nakaji M, Kudo M, Kim K, Hirai M, Hayashi y. Eosinophilic pseudotumor of the liver due top Ascaria suum infection. (Hepatol Res 23:306, 2002)
  • Kim SR, Matsuoka T, Maekawa Y, Yano Y, Imoto S, Kudo M, Shintani S, Ando K, Mita K, Fukuda K, Koterazawa T, Nakaji M, Ikawa H, Ninomiya T, Kim KI, Hirai M, Hayashi Y. Development of multicentric hepatocellular carcinoma after completion of interferon therapy. (J Gasteroenterol 37:663-668, 2002)
  • Kim SR, Maekawa Y, Ninomiya T, Imoto S, Matsuoka T, Ando K, Mita K, Ku K, Koterazawa T, Nakajima T, Fukuda K, Yano Y, Nakaji M, Kudo M, Kim KI, Hirai M, Hayashi Y. Multiple hypervascular liver nodules in a heavy drinker of alcohol. (J Gastroenterol Hepatol. May;20(5):795-799, 2005)
  • Kim SR, Kim KI, Maekawa Y, Imoto S, Ninomiya T, Mita K, Ando K, Fukuda K, Fuki S, Kudo M, Matsuoka T, Sasase N, Taniguchi M, Hayashi Y. Well differentiated HCC manifesting hyperattenuation on CT during arterial portography. (Hepato-Gasteroenterology 52(65):1559-1562, 2005)
  • Kim SR, Imoto S, Fuki S, Taniguchi M, Kim KI, Mita K, Ando K, Nakajima T, Hong HS, Fukuda K, Sasase N, Kudo M, Hayashi Y. Case of adult genotype C HBV carrier after acute hepatitis B, losing HBsAg and acquiring HBsAb after IFN and lamivudine treatment. (Hepatol Res. 36(2):149-152, 2006)
  • Kim SR, Kanda F, Kobessho H, Sugimoto K, Matsuoka T, Kudo M, Hayashi Y. Hepatocellular carcinoma metastasizing to the skull base involving multiple cranial nerves. (World J Gastroenterol. 12(41):6727-6729, 2006)
  • Kim SR, Ikawa H, Ando K, Mita K, Fuki S, Sakamoto M, Kanbara Y, Matsuoka T, Kudo M, Hayashi Y. Multistep hepatocarcinogenesis from a dysplastic nodule to well-differentiated hepatocellular carcinoma in a patient with alcohol-related liver cirrhosis. (World J Gastroenterol 13(8):1271-1274, 2007)
  • Kim SR, Ikawa H, Ando K, Mita K, Fuki S, Imoto S, Shimizu K, Kanbara Y, Sugimoto K, Fujii M, Kudo M, Matsuoka T, Hayashi Y.Small hepatocellular carcinoma presenting with massive metastasis in the peritoneum, mimicking sarcomatous tumor. (Hepatol Res 37(10):885-889, 2007)
  • Yano Y, Truong BX, Seo Y, Kato H, Miki A, Tanaka Y, Mizokami M, Kagawa A, Miyazaki H, Kasuga M, Azuma T, Hayashi Y. Japanese case of hepatitis B virus genotypes C/D hybrid. (Hepatol Res 37(12):1095-1099, 2007)
  • Kim SR, Imoto S, Ikawa H, Ando K, Mita K, Fuki S, Sakamoto M, Kanbara Y, Matsuoka T, Kudo M, Hayashi Y. Well-to moderately-differentiated HCC manifesting hyperattenuation on both CT during arteriography and arterial portography. (World J Gastroenterol 13(43):5775-5778, 2007)
  • Kim SR, Ando K, Mita K, Fuki S, Ikawa H, Kanbara Y, Imoto S, Matsuoka T, Hayashi Y, Kudo M. Superiority of CT arterioportal angiography to contrast-enhanced CT and MRI in the diagnosis of hepatocellular carcinoma in nodules smaller than 2 cm. (Oncology 72 Suppl 1:58-6, 2007)
  • Kim SR, Imoto S, Ikawa H, Ando K, Mita K, Shimizu K, Taniguchi M, Sasase N, Matsuoka T, Kudo M, Kawada N, Hayashi Y. Focal nodular hyperplasia-like lesion with venous washout in alcoholic liver cirrhosis. (Intern Med. 2008;47(21):1899-903)
  • Kim SR, Imoto S, Mita K, Taniguchi M, Sasase N, Muramatsu A, Kudo M, Kitai S, El-Shamy A, Hotta H, Hayashi Y. Pegylated interferon plus ribavirin combination therapy for chronic hepatitis C with high viral load of serum hepatitis C virus RNA, genotype 1b, discontinued on attaining sustained virological response at week 16 after onset of acute pancreatitis. (Digestion. 2009;79(1):36-9)
  • Kim SR, Imoto S, Nakajima T, Ando K, Mita K, Fukuda K, Nishikawa R, Koma Y, Matsuoka T, Kudo M, Hayashi Y. Scirrhous hepatocellular carcinoma displaying atypical findings on imaging studies. (World J Gastroenterol. 2009 May 14;15(18):2296-9)
  • Kim SR, Imoto S, Nakajima T, Ando K, Mita K, Taniguchi M, Sasase N, Matsuoka T, Kudo M, Hayashi Y. Well-differentiated hepatocellular carcinoma smaller than 15 mm in diameter totally eradicated with percutaneous ethanol injection instead of radiofrequency ablation. (Hepatol Int. 2009 Jun;3(2):411-5.)
  • Kim SR, Imoto S, Kudo M, Mita K, Taniguchi M, Kim KI, Sasase N, Shoji I, Nagano-Fujii M, El-Shamy A, Hotta H, Nagai T, Nagata Y, Hayashi Y. Double-filtration plasmapheresis plus IFN for HCV-1b patients with non-sustained virological response to previous combination therapy: early viral dynamics. (Intervirology. 2010;53(1):44-8.)
  • Asada N, Ishii S, Wakahashi K, Kawano H, Kawamori Y, Nishikawa S, Minagawa K, Okamura A, Shimoyama M, Katayama Y, Hayashi Y, Itoh T, Tanimoto M, Matsui T. Progressive osteosclerosis and visceral calcification after cord blood transplantation. (Int J Hematol. 2010 Apr;91(3):542-5.)
  • Kim SR, Imoto S, Kudo M, Nakajima T, Ando K, Mita K, Fukuda K, Hong HS, Lee YH, Nakashima K, Shoji I, Nagano-Fujii M, Hotta H, Hayashi Y. Autoimmune thrombocytopenic purpura during pegylated interferon alpha treatment for chronic hepatitis C. (Intern Med. 2010;49(12):1119-22.)
  • Kim SR, Imoto S, Kudo M, Nakajima T, Ando K, Mita K, Fukuda K, Hong HS, Lee YH, Nakashima K, Shoji I, Nagano-Fujii M, Hotta H, Hayashi Y. Histiocytic sarcoma with two immunohistopathologically distinct populations. (Intern Med. 2010;49(12):1119-22.)
  • Wakahashi K, Shimoyama M, Katayama Y, Minagawa K, Yoshida K, Sasaki R, Nakayama S, Yokozaki H, Yanagita E, Itoh T, Hayashi Y, Matsui T. Autoimmune thrombocytopenic purpura during pegylated interferon alpha treatment for chronic hepatitis C. (Int J Hematol. 2010 Nov;92(4):642-6.)


Review Article

  • Hayashi Y, Wang W, Ninomiya T, Nagano H, Ohta K, Itoh H. Invited Reveiw Article. The Liver-Enriched Transcription Factors and Differentiation of Human Hepatocellular Carcinoma (J Clin Pathol (Molec Pathol) 52(1):19-24, 1999)
  • Hardianti MS, Tatsumi E, Syampurnawati M, Furuta K, Suzuki A, Saigo K, Kawano S, Takenokuchi M, Kumagai S, Matsuo Y, Koizumi T, Takeuchi M. Presence of somatic hypermutation and activation-induced cytidine deaminase in acute lymphoblastic leukemia L2 with t(14;18)(q32;q21). (Eur J Haematol. 74(1):11-19, 2005)

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