過去3年の英文論文

2017
 1. Journal: Oncotarget
Title: Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry
Author: Shin Nishiumi, Takashi Kobayashi, Shuichi Kawana, Yumi Unno, Takero Sakai, Koji Okamoto, Yasuhide Yamada, Kazuki Sudo, Taiki Yamaji, Yutaka Saito, Yukihide Kanemitsu, Natsuko Tsuda Okita, Hiroshi Saito, Shoichiro Tsugane, Takeshi Azuma, Noriyuki Ojima, Masaru Yoshida
  2. Title:Evaluation of a novel system for analyzing hydrophilic blood metabolites
Author: Shin Nishiumi, Keisuke Shima, Takeshi Azuma, Masaru Yoshida

Journal: Journal of Bioscience and Bioengineering
  3.
Title: Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics
Author: Yuichi Hirata, Takashi Kobayashi, Shin Nishiumi, Kodai Yamanaka, Takashi Nakagawa, Seiji Fujigaki, Takao Iemoto, Makoto Kobayashi, Takuji Okusaka, Shoji Nakamori, Masashi Shimahara, Takaaki Ueno, Akihiko Tsuchida, Naohiro Sata, Tatsuya Ioka, Yohichi Yasunami, Tomoo Kosuge, Takashi Kaneda, Takao Kato, Kauhiro Yagihara, Shigeyuki Fujita, Tesshi Yamada, Kazufumi Honda, Takeshi Azuma, Masaru Yoshida
Journal: Clinica Chimica Acta

  4.
Journal: European Journal of Pharmacology
Title: Astilbin from Engelhardtia chrysolepis Enhances Intestinal Barrier Functions in Caco-2 Cell Monolayers
Author: Tatsuo Nakahara, Yosuke Nishitani, Shin Nishiumi, Masaru Yoshida, Takeshi Azuma
  5.
Journal: Rapid Communications in Mass Spectrometry
Title: The use of on-line SFE-SFC/MS/MS to analyze disease biomarkers in dried serum spots compared with serum analysis using LC/MS/MS

Author: Makoto Suzuki , Shin Nishiumi , Takashi Kobayashi , Arata Sakai , Yosuke Iwata , Takato Uchikata , Yoshihiro Izumi, Takeshi Azuma , Takeshi Bamba, Masaru Yoshida
  6.
Author: Fukumoto T., Nishiumi S., Fujiwara S., Yoshida M., Nishigori C.
Title: Novel serum metabolomics-based approach by gas chromatography/triple quadrupole mass spectrometry for detection of human skin cancers: candidate biomarkers.

Journal: The Journal of Dermatology
 
7. Title: Adrenic acid as an inflammation enhancer in non-alcoholic fatty liver disease
Author: Saut Horas H Nababan, Shin Nishiumi, Yuki Kawano, Takashi Kobayashi, Masaru Yoshida, Takeshi Azuma
Journal: Archives of Biochemistry and Biophysics

 
8. Title: Alterations in metabolic pathways in stomach of mice infected with Helicobacter pylori
Journal: Microbial Pathogenesis
Author: Shin Nishiumi, Masaru Yoshida, Takeshi Azuma

 
9. Author: Yamashita Y., Nishiumi S., Kono S., Takao S., Azuma T., Yoshida M.
Title: Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer.
Journal: BMC Cancer

 
10. Author: Ezaki T., Nishiumi S., Azuma T., Yoshida M.
Title: Metabolomics for the early detection of cisplatin-induced nephrotoxicity.
Journal: Toxicology Research

 11. Author: TOMOKO INAGAKI, SHIN NISHIUMI, YOSHIYUKI ITO, AKIYO YAMAKAWA, YUKINAO YAMAZAKI, MASARU YOSHIDA,TAKESHI AZUMA
Title: Associations between cagA, vacA, and the clinical outcomes of Helicobacter pylori infections in Okinawa, Japan
Journal: Kobe Journal of Medical Sciences


2016
 1.Shimoda A, Ueda K, Nishiumi S, Murata-Kamiya N, Mukai SA, Sawada S, Azuma T, Hatakeyama M, Akiyoshi K. Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA. Sci Rep. 2016 Jan 7;6:18346.
 2. Article: Metabolomics Title: LC-MS/MS-based metabolome analysis detected changes in the metabolic profiles of small and large intestinal adenomatous polyps in ApcMin/+mice
 Author: Makoto Suzuki, Shin Nishiumi, Takashi Kobayashi, Takeshi Azuma, Masaru Yoshida
 3.
Journal: Biomarkers in Medicine
Title: Pancreatic cancer screening using a multiplatform human serum metabolomics system

Authors: Arata Sakai, Makoto Suzuki, Takashi Kobayashi, Shin Nishiumi, Kodai Yamanaka, Yuichi Hirata, Takashi Nakagawa, Takeshi Azuma, Masaru Yoshida

2015
 1. Masaya Saito, Hirotaka Hirano, Yoshihiko Yano, Kenji Momose, Masaru Yoshida, Takeshi Azuma. Serum level of taurine would be associated with the amelioration of minimal hepatic encephalopathy in cirrhotic patients. Hepatology research 2015, in press
 2. Masaya Saito, Hirotaka Hirano, Yoshihiko Yano, Hiroki Hayashi, Kenji Momose, Akihiro Minami, Yuki Kawano, Masaru Yoshida, Takeshi Azuma. Recent topics of diagnosis and treatment in minimal hepatic encephalopathy of cirrhotic patients. Journal of Hepatitis 2015, in press
 3. Masaya Saito, Yoshihiko Yano, Hirotaka Hirano, Kenji Momose, Kentaro Mouri, Akitoyo Hishimoto, Masaru Yoshida, Takeshi Azuma. The serum level of NX-DCP-R, but not DCP, is not increased in alcoholic liver disease without hepatocellular carcinoma. Cancer Biomarkers 2015, in press
 4.
Masaya Saito, Yoshihiko Yano, Hirotaka Hirano, Kenji Momose, Yuki Kawano, Masaru Yoshida, Takeshi Azuma.Visceral fat accumulation is associated with increased mortality rate after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma. J Cancer Ther, 2015 in press
 5. Ohbuchi K., Nishiumi S., Fujitsuka N., Hattori T., Yamamoto M., Inui A., Azuma T., Yoshida M. (2015) Rikkunshito ameliorates cancer cachexia partly through elevation of glucarate in plasma. Evidence-Based Complementary and Alternative Medicine, 2015 (2015), 871832, 11 pages.

2014
 1. Masaya Saito, Yoshihiko Yano, Akihiro Minami, Hirotaka Hirano, Kenji Momose, Maki Sugimoto, Masaru Yoshida, Takeshi Azuma.Branched-chain amino acid granules improve non-protein respiratory quotient after radiofrequency ablation. Intern Med 2014, in press
 2.
Fumiaki Kawara, Jun Inoue, Mamoru Takenaka, Namiko Hoshi, Atsuhiro Masuda, Shin Nishiumi, Hiromu Kutsumi, Takeshi Azuma, Takeshi Ohdaira.The Influences of Pepsin Concentrations and pH Levels on the Disinfective Activity of Ozone Nanobubble Water against Helicobacter pylori.Digestion 2014, in press.
 3.
Daisuke Watanabe, Makoto Ooi, Namiko Hoshi, Michitaka Kohashi, Tomoo Yoshie, Nobunao Ikehara, Masaru Yoshida, Emmy Yanagita, Takashi Yamasaki, Tomoo Itoh, Takeshi Azuma. Successful treatment of Cronkhite-Canada syndrome using anti-TNF antibody therapy.Endoscopy Cases and Techniques Library(CTL).
 4. Toyonaga T, Man-i M, Morita Y, Azuma T. Endoscopic submucosal dissection (ESD) versus Simplified / Hybrid ESD. Gastrointest Endoscopy Clin N Am; 24(4): 191-199, 2014. http://dx.doi.org/10.1016/j.giec.2013.11.004
 5. Toyonaga T, Azuma T. How to prevent complications at ESD of colorectal lesions. Video Journal and Encyclopedia of GI Endoscopy; 1(2): 365-6-366, 2013 http://dx.doi.org/10.1016/S2212-0971(13)70161-4
 6. Ishida T1, Morita Y, Hoshi N, Yoshizaki T, Ohara Y, Kawara F, Tanaka S, Yamamoto Y, Matsuo H, Iwata K, Toyonaga T, Azuma T. Disseminated nocardiosis during systemic steroid therapy for the prevention of esophageal stricture after endoscopic submucosal dissection.Dig Endosc. 2014 May 29.
 7. Kawano Y, Ersoy BA, Li Y, Nishiumi S, Yoshida M, Cohen DE. Thioesterase Superfamily Member 2 (Them2) and Phosphatidylcholine Transfer Protein (PC-TP) Interact To Promote Fatty Acid Oxidation and Control Glucose Utilization. Mol Cell Biol. 2014 Jul 1;34(13):2396-408
 8. Terashima Y., Nishiumi S., Minami A., Kawano Y., Hoshi N., Azuma T., Yoshida M. (2014) Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis. Archives of Biochemistry and Biophysics, 555-556, 55-65.
 9. Nishiumi S., Suzuki M., Kobayashi T., Matsubara A., Azuma T., Yoshida M. Metabolomics for Biomarker Discovery in Gastroenterological Cancer. Metabolites, 4, 547-571 (2014), Review.
 10. Atsuhiro Masuda, Hideyuki Shiomi, Tomokazu Matsuda, Mamoru Takenaka, Yoshifumi Arisaka, Takeshi Azuma, and Hiromu KutsumiThe relationship between pancreatic atrophy after steroid therapy and diabetes mellitus in patients with autoimmune pancreatitis
 11. Suzuki M., Nishiumi S., Matsubara A., Azuma T., Yoshida M. (2014) Metabolome analysis for discovering biomarkers of gastroenterological cancer. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 966 59-69.
12. Kohashi M., Nishiumi S., Ooi M., Yoshie T., Matsubara A., Suzuki M., Hoshi N., Kamikozuru K., Yokoyama Y., Fukunaga K., Nakamura S., Azuma T., Yoshida M. A novel gas chromatography mass spectrometry-based serum diagnostic and assessment approach to ulcerative colitis. Journal of Crohn's & colitis, 8, 1010-1021 (2014).
 13. Yamamoto K., Nishiumi S., Yang L., Klimatcheva E., Pandina T., Takahashi S., Matsui H., Nakamura M., Zauderer M., Yoshida M., Azuma T. Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection. Mucosal Immunology, 7, 1244-1254 (2014).
 14. Iwamoto A., Tanahashi T., Okada R., Yoshida Y., Kikuchi K., Keida Y., Murakami Y., Yang L., Yamamoto K., Nishiumi S., Yoshida M. Azuma T. Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes. Gut Pathogens, 6, 27 (2014)
 15. Matsubara A., Izumi Y., Nishiumi S., Suzuki M., Azuma T., Fukusaki E., Bamba T., Yoshida M. Supercritical fluid extraction as a preparation method for mass spectrometry of dried blood spots. Journal of Chromatography B, 969, 199-204 (2014).
  16. Hirotaka Hirano, Masaya Saito, Yoshihiko Yano, Kenji Momose, Masaru Yoshida, Atsushi Tanaka, Takeshi Azuma. Chronic liver disease questionnaire would be a primary screening tool of neuropsychiatric test detecting minimal hepatic encephalopathy of cirrhotic patients. Hepatol Res, in press
  17. Masaya Saito, Yoshihiko Yano, Hirotaka Hirano, Kenji Momose, Masaru Yoshida, Takeshi Azuma. Serum NX-DCP is a new noninvasive model for predicting significant liver fibrosis in chronic hepatitis C. Hepat Mon, in press



2013

 1.Lee J.W., Nishiumi S., Yoshida M., Fukusaki E., Bamba T.Simultaneous profiling of polar lipids by supercritical fluid chromatography/tandem mass spectrometry with methylation.Journal of Chromatography A.
 2.Kobayashi T., Nishiumi S., Ikeda A., Yoshie T., Sakai A., Matsubara A., Izumi Y., Tsumura H., Tsuda M., Nishisaki H., Hayashi N., Kawano S.,Fujiwara Y., Minami H., Takenawa T., Azuma T., Yoshida M. A novel serum metabolomics-based diagnostic approach to pancreatic cancer. Cancer Epidemiology,Biomarkers Prevention
 3.Ohira H., Fujioka Y., Katagiri C., Mamoto R., Aoyama-Ishikawa M., Amako K., Izumi Y., Nishiumi S., Yoshida M., Usami M., Ikeda M.Butyrate attenuates inflammation and lipolysis generated by the interaction of adipocytes and macrophages. Journal of Atherosclerosis and Thrombosis.
 4.Masaya Saito, Yasushi Seo, Yoshihiko Yano, Keiichiro Uehara, Shigeo Hara, Kenji Momose, Hirotaka Hirano, Hiroshi Yokozaki, Masaru Yoshida, Takeshi Azuma. Portal venous tumor growth- type of hepatocellular carcinoma without liver parenchyma tumor nodules: a case report. Ann Hepatol 2013, in press
 5. Arantes V, Forero Pineros EA, Yoshimura K, Toyonaga T.Advances in the management of early esophageal carcinoma.Rev Col Bras Cir. 2012 Dec;39(6):534-543
 6.Okada T., Fukuda S., Hase K., Nishiumi S., Izumi Y., Yoshida M., Hagiwara T., Kawashima R., Yamazaki M., Oshio T., Otsubo T., Inagaki-Ohara K., Kakimoto K., Higuchi K., Kawamura Y.I., Ohno H., Dohi T. Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice. Nature Communications.
 7.Kimoto A., Nishiumi S., Kobayashi T., Terashima Y., Suzuki H., Takeuchi J., Azuma T., Komori T., Yoshida M. A novel gas chromatography mass spectrometry-based serum screening method for oral squamous cell carcinoma. Head and Neck Oncology (2013), 5, 40.
 8.Masaya Saito, Yoshihiko Yano, Akihiro Minami, Kenji Momose, Hirotaka Hirano, Takashi Yamasaki, Tomoo Itoh, Masaru Yoshida, Takeshi Azuma. Autoimmune-associated hemophagocytic syndrome originating from autoimmune hepatitis with a successful response to therapy: a case report. Intern Med 2013, in press
 9.Masaya Saito, Yasushi Seo, Yoshihiko Yano, Kenji Momose, Hirotaka Hirano, Masaru Yoshida, Takeshi Azuma. Serum albumin and prothrombin time before entecavir treatment in chronic hepatitis B or cirrhosis are related to amelioration of liver function after treatment. Eur J Gastroenterol Hepatol 2013, in press
 10.Kakuta S., Bando Y., Nishiumi S., Yoshida M., Fukusaki E., Bamba T. (2013) Metabolic profiling of oxidized lipid-derived volatiles in blood by gas chromatography/mass spectrometry with in-tube extraction. Mass Spectrometry, 2, A0018.
 11.Yamada S., Kato S., Matsuhisa T., Makonkawkeyoon L., Yoshida M., Chakrabandhu T., Lertprasertsuk N., Suttharat P., Chakrabandhu B., Nishiumi S., Chongraksut W., Azuma T. (2013) Predominant mucosal IL-8 mRNA expression in non-cagA Thais is risk for gastric cancer. World journal of gastroenterology, 19, 2941-2949.
 12.Yamada T., Uchikata T., Sakamoto S., Yokoi Y., Nishiumi S., Yoshida M., Fukusaki E., Bamba T. (2013) Supercritical fluid chromatography/Orbitrap mass spectrometry based lipidomics platform coupled with automated lipid identification software for accurate lipid profiling. Journal of Chromatography A, 1301, 237-42.
 13.Ishida T., Miki I., Tanahashi T., Yagi S., Kondo Y., Inoue J., Kawauchi S., Nishiumi S., Yoshida M., Maeda H., Tode C., Takeuchi A., Nakayama H., Azuma T., Mizuno S. (2013) Effect of 18β-glycyrrhetinic acid and hydroxypropyl γ cyclodextrin complex on indomethacin-induced small intestinal injury in mice. European journal of pharmacology, 714, 125-131.

2012
 1.Masaya Saito,Yasushi Seo,Yoshihiko Yano,Akira Miki,Yukiko Morinaga,Tomoo Itoh,Masaru Yoshida,Takeshi Azuma.A Hepatocellular Carcinoma Developed Following 18 Years from Sustained Virological Response to Interferon Therapy in a Patient with Chronic Hepatitis C:Case Report and Literature Review.Clinical Journal of Gastroenterology (2012)5: 119-126,DOI:10.1007/s12328-012-0284-7
 2.Masaya Saito, Yasushi Seo, Yoshihiko Yano, Akira Miki, Kenji Momose, Hirotaka Hirano, Masaru Yoshida, Takeshi Azuma Liver dysfunction and survival in patients with hepatocellular carcinoma treated by transarterial chemoembolization. Aliment Pharmacol Ther2012 Apr;35(7):861-2; author reply 862-3. doi: 10.1111/j.1365-2036.2012.05021.x.
 3.Man-i M, Morita Y, Fujita T, East JE, Tanaka S, Wakahara C, Yoshida M, Hayakumo T, Kutsumi H, Inokuchi H, Toyonaga T, Azuma T. Endoscopic submucosal dissection for gastric neoplasm in patients with co-morbidities categorized according to the ASA Physical Status Classification. Gastric Cancer2012 Mar 2. [Epub ahead of print]
 4.El-Shamy A, Shoji I, Kim SR, Ide Y, Imoto S, Deng L, Yoon S, Fujisawa T, Tani S, Yano Y, Seo Y, Azuma T, Hotta H.Sequence Heterogeneity in NS5A of Hepatitis C Virus Genotypes 2a and 2b and Clinical Outcome of Pegylated-Interferon/Ribavirin Therapy.PLoS One. 2012;7(2):e30513. Epub 2012 Feb 2.
 5.Masaya Saito, Yasushi Seo, Yoshihiko Yano, Akira Miki, Masaru Yoshida, Takeshi Azuma. A high value of serum des-γ-carboxy prothrombin before hepatocellular carcinoma treatment can be associated with long-term liver dysfunction after treatment. J Gastroenterol 2012 Mar 24. [Epub ahead of print]
 6.Yoshie T., Nishiumi S., Izumi Y, Sakai A., Inoue J., Azuma T., Yoshida M.Regulation of the metabolite profile by an APC gene mutation in colorectal cancer.Cancer Science.(2012)DOI: 10.1111/j.1349-7006.2012.02262.
 7.Ken Kurokawa,Toshihito Tanahashi,Tsutomu Iima,Yuta Yamamoto,Yoko Akaike,Kensei Nishida,Kiyoshi Masuda,Yuki Kuwano,Yoshiki Murakami,Masakazu Fukushima,Kazuhito Rokutan.
Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells,J Gastroenterol,doi 10.1007/s00535-012-0547-6
 8.Jun Inoue; Shin Nishiumi; Yoshimi Fujishima; Atsuhiro Masuda; Hideyuki Shiomi; Koji Yamamoto; Masayuki Nishida; Takeshi Azuma; Masaru Yoshida.Autophagy in the intestinal epithelium regulates Citrobacter rodentium infection.Archives of Biochemistry and Biophysics.Volume 521, Issues 1–2May 2012, Pages 95–101
 9.Sakai A., Nishiumi S., Shiomi Y., Kobayashi T., Izumi Y., Kutsumi H., Hayakumo T., Azuma T. Yoshida M.Metabolomic analysis to discover candidate therapeutic agents against acute pancreatitis.Archives of Biochemistry and Biophysics.Volume 522, Issue 21,5 June 2012, Pages 107–12
 10.Tsuyoshi Sanuki, Tsuyoshi Fujita, Hiromu Kutsumi, Takanobu Hayakumo, Shun-ichi Yoshida, Hideto Inokuchi, Manabu Murakami, Yoshihiro Matsubara, Hajime Kuwayama, Takashi Kawai, Hideki Miyaji, Takashi Fujisawa, Shuichi Terao, Yukinao Yamazaki, Takeshi Azuma, CARE STUDY GROUP. Rabeprazole reduces the recurrence risk of peptic ulcers associated with low-dose aspirin in patients with cardiovascular or cerebrovascular disease: a prospective randomized active-controlled trial. J Gastroenterol 2012 Apr 17. [Epub ahead of print]
 11.Nishiumi S.#, Fujishima Y.#, Inoue J., Masuda A., Azuma T., Yoshida M. (#, equally contribute) Autophagy in the intestinal epithelium is not involved in the pathogenesis of intestinal tumors. Biochemical and Biophysical Research Communications, 2012Volume 421, Issue 4,18 May 2012, Pages 768–772
 12.Tanaka S, Toyonaga T, Obata D, Ishida T, Morita Y, Azuma T.Endoscopic double-layered suturing: a novel technique for closure of large mucosal defects after endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD).Endoscopy. 2012 May;44 Suppl 2:E153-4. Epub 2012 May 23. No abstract available.
 13.Nishiumi S., Kobayashi T., Ikeda A., Yoshie T., Kibi M., Izumi Y., Okuno T., Hayashi N., Kawano S., Takenawa T., Azuma T., Yoshida M.A novel serum metabolomics-based diagnostic approach for colorectal cancer.PLoS ONE.(in press)
 14.Takashi Toyonaga et. al.1635 Endoscopic submucosal dissection cases in the esophagus, stomach, and colorectum:Complication rates and long-term outcomes.Surgical Endoscopy.(in press)
 15.Nishiumi S., Mukai R., Ichiyanagi T.,Ashida H.Suppression of the lipopolysaccharide and galactosamine-induced hepatic inflammation by red grape pomace.Journal:Journal of Agricultural and Food Chemistry
 16.Atsuhiro Masuda,et.al.A case of lipomatous pseudohypertrophy of the pancreas diagnosed by EUS-FNA.Clinical Journal of Gastroenterology: Volume 5, Issue 4 (2012), Page 282-286

 17.Ishida T., Nishiumi S., Tanahashi T., Yamasaki A., Yamazaki A., Akashi T., Miki I., Kondo Y., Kawauchi S., Azuma T., Yoshida M., Mizuno S. Linoleoyl ethanolamide reduces lipopolysaccharide-induced inflammation in macrophages and ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis in mice. European Journal of Pharmacology
 18. Hashimoto F., Nishiumi S., Miyake S., Takeichi H., Chitose M., Ohtsubo H., Ishimori S., Ninchoji T., Hashimura Y., Kaito H., Morisada, N., Morioka, I., Fukuoka H., Yoshida M., Iijima K. Metabolomics analysis of umbilical cord blood clarifies changes in saccharides associated with delivery method. Early Human Development
 19.Masaya Saito,Yasushi Seo, Yoshihiko Yano, Akira Miki, Kenji Momose,Hirotaka Hirano,Masaru Yoshida, Takeshi Azuma. Alteration of non-protein respiratory quotient after hepatocellular carcinoma treatment can be related to des-γ-carboxy prothrombin before treatment.SpringerPlus 2012(in press)
 20.Masaya Saito, Yasushi Seo, Yoshihiko Yano, Kenji Momose, Hirotaka Hirano, Masaru Yoshida, Takeshi Azuma. Successful treatment by coil embolization of symptomatic intrahepatic portosystemic venous shunt through a patent ductus venosus in a non-cirrhotic adult: a case report. Intern Med 2012, in press
 21.Hirotaka Hirano, Masaya Saito, Yasushi Seo, Yoshihiko Yano, Takeshi Azuma. NX-DCP as a novel biomarker would be related to liver function in cirrhotic patients with hepatocellular carcinoma. Eur J Gastroenterol Hepatol 2012, in press
 22.Nishida M., Yoshida M., Nishiumi S., Furuse M., Azuma T. Claudin-2 regulates colorectal inflammation via myosin light chain kinase dependent signaling. Digestive Diseases and Sciences.2012, in press
 23.Masaya Saito, Yasushi Seo, Yoshihiko Yano, Kenji Momose, Hirotaka Hirano,Masaru Yoshida, Takeshi Azuma. Reduction in non-protein respiratory quotient is related to overall survival after hepatocellular carcinoma treatment. PLoS One 2012, in press
2011

 1. Chinzei R,et.al. Vitamin K3 attenuates cerulein-induced acute pancreatitis through inhibition of the autophagic pathway. Pancreas. 2011 Jan;40(1):84-94.
 2. Kobayashi K,et.al. Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNA polymerase inhibition and anti-inflammation. Med Chem. 2011 Jan 1;7(1):37-44.
 3. Furuta K,et.al. Birth and death of genes linked to chromosomal inversion. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1501-1506.
4. Miwa H, et. al.the Japan TREND study group. Randomised clinical trial: efficacy of the addition of a prokinetic, mosapride citrate, to omeprazole in the treatment of patients with non-erosive reflux disease-a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2011 Feb;33(3):323-332.
 5.Fujishima Y,et.al. Autophagy in intestinal epithelialum reduces endotoxin-induced inflammatory responses by inhibiting NF-kB activation. Arch Biochem Biophys. 2011 Feb 15;506(2):223-235.
 6. Nishiumi S,et.al. Anti-inflammatory lipid mediators derived from w-6 and w-3 polyunsaturated fatty acids against inflammatory bowel diseases. Antiinflamm Antiallergy Agents Med Chem. 2011 Feb,10(1); 66-71.
 7.Bouike G, Nishitani Y, Shiomi H, Yoshida M, Azuma T, Hashimoto T, Kanazawa K and Mizuno M. An orally administered extract of Agaricus blazei Murill suppressed OVA-sensitized allergy in mice. Evid Based Complement Alternat Med. 2011;2011. pii: 532180
 8. Ishikawa Y,et.al. Antigen-Specific IgG Amelliorates Allergic Airway Inflammation via Fcg Receptor IIB on Dendritic Cells. Resp Res. 2011 Apr 10;12(1):42.
 9. Tsao SKK, Toyonaga T, Morita Y, Fujita T, Hayakumo T, Azuma T. Modified Fish-Line Traction System in Endoscopic Submucosal Dissection of Large Oesophageal Tumour. Endoscopy. 2011;43 Suppl 2:E119.

 10. Fujiwara S,et.al. A randomized controlled trial of Rebamipide plus Rabeprazole for artificial ulcer healing after Endoscopic Submucosal Dissection. J Gastroenterol. J Gastroenterol. 2011 May;46(5):595-602.

 11. Morita Y,et.al. A case of small early gastric cancer that was successfully detected by narrow band imaging magnifying endoscopy. Dig Endosc. 2011 May;23 Suppl 1:89-91.
 12.Bouike G,et.al. An orally administered extract of Agaricus blazei Murill suppressed OVA-sensitized allergy in mice. Evid Based Complement Alternat Med.Article ID 532180, 11 pages
doi:10.1155/2011/532180

 13. Shiomi Y,et.al. A GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium. Inflamm Bowel Dis. Nov;17(11):2261-74.(*correspondence)
 14.Nishiumi S, Miyamoto S, Kawabata K, Ohnishi K, Mukai R, Murakami A, Ashida H, Terao J. Dietary flavonoids as cancer-preventive and therapeutic biofactors. Front Biosci (Schol Ed). 2011 Jun 1;3:1332-62.
 15. Kitajima K, et.al. A case of Budd-Chiari syndrome: Gd-EOB-DTPA-enhanced MR findings. Magn Reson Imaging. May;29(4):579-83. Epub 2011 Jan 8
 16.Mizushina Y,et.al. Effects of the Intermediates betweek Vitamins K2 and K3 on mammalian DNA polymerase Inhibition and Anti-Inflammatory Activity. Int J Mol Med. 2011 Feb 10;12(2):1115-32.
 17. Toyonaga T,et.al. Endoscopic Submucosal Dissection using the Flush knife and the Flush knife BT. Techniques in Gastrointestinal Endoscopy. 2011 Jan 13(1):84-90
 18.Tanaka S, Obata D, Chinzei R, Yoshida S, Sanuki T, Morita Y, Yoshida M, Fujita T, Toyonaga T, Kutsumi H, Inokuchi H, Azuma T. Surveillance after colorectal polypectomy; comparison between Japan and U.S. Kobe J Med Sci. 2011 56(5):E204-E213.
 19.Furumatsu K, et.al. A role of the aryl hydrocarbon receptor in epithelium immunity and attenuation of dextran sodium sulfate-induced colitis by activation of the aryl hydrocarbon receptor. Dig Dis Sci.2011 Sep;56(9):2532-44.(*correspondence)
 20.Hori S,et.al. A metabolomic approach to detect early stages of lung cancers. Lung Cancer.2011 Nov;74(2):284-92.(*correspondence)
 21.Yamamoto K,et.al.Helicobacter suis KB1 derived from pig gastric lymphoid follicles induces the formation of gastric lymphoid follicles in mice through the activation of B cells and CD4 positive cells. Microbes Infect.2011 Jul;13(7):697-708(*correspondence)
 22.Mizushina Y,et. al. Inhibition of DNA polymerase λ, a DNA repair enzyme, and anti-inflammation: chemical knocked out analysis for DNA polymerase λ by curcumin derivatives. DNA Repair Book 3 InTech(in press)
 23.Kawai M, et. al. Evolution in an oncogenic bacterial species: Helicobacter pylori East Asian genomes. BMC Microbiology.2011 May 16;11(1):104.
 24. Mimura M, et. al. AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene. Int J Cancer. (in press)
 25. Ooi M, et. al. The GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis. Inflamation Res.2011 Sep;60(9):831-40.(*correspondence)
 26. Sugimoto M, et. al. da Vinci robotic single-incision cholecystectomy and hepatectomy using single-channel GelPort access. J Hepatobiliary Pancreat Sci. 2011 Jul;18(4):493-8.
 27.Tsugawa H,et. al. Practical Non-targeted Gas Chromatography/Mass Spectrometry-based Metabolomics Platform for Metabolic Phenotype Analysis. J Biosci Bioeng. (in press)
 28.Kondo Y, et. al. Serum fatty acid profiling of colorectal cancer by gas chromatography/mass spectrometry. Biomarker in Medicine. 2011 Aug;5(4):451-60.(*correspondence)
 29.Tanaka S, et. al. Clinicopathological characteristics of abnormal micro-lesions at the oro-hypopharynx detected by a magnifying narrow band imaging system. Digestive Endscopy. (in press)
 30.Ishida T, et. al. Inhibitory effects of glycyrrhetinic acid on DNA polymerase and inflammatory activities. Evidence-based Compl and Alt. Medicine.2012 (2012), Article ID 650514, 9 pages
doi:10.1155/2012/650514

 31.Mimura T,et. al.IFN-γ plays an essential role in the pathogenesis of gastric lymphoid follicles formation caused by Helicobacter suis infection. FEMS Immunol Med Microbiol. 2011 Oct;63(1):25-34.(*correspondence)
 32.Ikeda A, et. al. Serum metabolomics as a novel diagnostic approach for gastrointestinal cancer.Biomedical Chromatography. (in press)
 33.Aoganghua,et.al.Inhibitory effects of vitamin K3 derivatives on DNA polymerase and inflammatory activities.Int J Mol Med.2011 Dec;28(6):937-45.
 34.Kido M, Watanabe N, Aoki N, Iwamoto S, Nishiura H, Maruoka R, Ikeda A, Azuma T, Chiba T.Dual roles of CagA protein in Helicobacterpylori-induced chronic gastritis in mice.Biochem Biophys Res Commun. 2011 Aug 26;412(2):266-72. Epub 2011 Jul 28.
 35.Slayman YB, Yoshida M*, Tanaka H, Nishiumi S, Mimura T, Nobutani K, Yamamoto K, Takenaka M, Ota H, Takahashi S, Matsui H, Nakamura M, Blumberg RS, Azuma T. Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice. Mucosal Immunol .(in press) (*correspondence)
 36.Shinwa Tanaka, Yoshinori Morita, Tsuyoshi Fujita, Chika Wakahara, Atsuki Ikeda, Takashi Toyonaga, Takeshi Azuma.Ex vivo pig training model for esophageal endosopic submucosal dissection (ESD) for endoscopists with experience in gastric ESD.Surgical Endoscopy.(in press)
 37.Yoshida M*, Hatano N, Nishiumi S, Irino Y, Izumi Y, Takenawa T, Azuma T. Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry. J Gastroenterol. (in press) (*correspondence)
 38.Ando T, Mizuno S, Ishida T, Kondo Y, Miki I, Yoshida M, Azuma T, Ishikawa T, Takagi T, Yagi N, Kokura S, Naito Y, Yoshikawa T, Asakawa A, Inui A. Plasma ghrelin isoforms and gastric ghrelin O-acyltransferase expression are influenced by Helicobacter pylori status. Nutrition. (in press)
 39.Shinwa Tanaka,Takashi Toyonaga,Daisuke Obata,Tsukasa Ishida,Yoshinori Morita,Takeshi Azuma.Endoscopic double-layered suturing method’’, a novel endoscopic closure technique for large mucosal defects after EMR or ESD.Endoscopy(UCTN)(in press)
 40. Kutsumi H, Nobutani K, Kakuyama S, Shiomi H, Funatsu E, Masuda A, Sugimoto M, Yoshida M, Fujita T, Hayakumo T, Azuma T. Sphincter of Oddi disorder: what is the clinical issue? Clin J Gastroenterol (2011) 4:364–370
 41.Saito M, Seo Y, Yano Y, Miki A, Morinaga Y, Itoh T, Yoshida M, Azuma T.Sonazoid-enhanced ultrasonography and Ga-EOB-DTPA-enhanced MRI of hepatic inflammatory pseudotumor: a case report. Intern Med. in press.
 42. Nishiumi S, Hosokawa K, Anetai M, Shibata T, Mukai R, Yoshida K.I, Ashida H. Antagonistic effect of the Ainu-selected traditional beneficial plants on the transformation of an aryl hydrocarbon receptor.Journal of Food Science.
 43.Imada S, Tanaka A, Nishiumi S, Ashida H.Concentration of Catechins and Caffeine in Black Tea Affects Suppression of Fat Accumulation and Hyperglycemia in High-fat Diet-fed Mice.Food Science and Technology Research.2011(17)353-359
 44.Saito M, Seo Y, Yano Y,Miki A, Yoshida M, Azuma T. Short-term reductions in non-protein respiratory quotient and prealbumin can be associated with the long-term deterioration of liver function after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma. J Gastroenterol. in press
 45.Tanaka S, Toyonaga T, Obata D, Ishida T, Morita Y, Azuma T.Endoscopy. 2012 May;44 Suppl 2:E153-4. Epub 2012 May 23. No abstract available. Endoscopy. 2012 May;44 Suppl 2:E153-4. Epub 2012 May 23. No abstract available.

2010
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 3. Hirai I, et. al. Infection of less virulent Helicobacter pylori strains in asymptomatic healthy individuals in Thailand as a potential contributing factor to the Asian enigma. Microbes Infect. 2010 Mar;12(3):227-30.
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 12. Utsumi T, et. al. Serologic and molecular characteristics of hepatitis B virus among school children in East Java, Indonesia. Am J Trop Med Hyg. 2010 Jul;83(1):189-93.
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 14. ToyonagaT, et. al. Retrospective study of technical aspects and complications of endoscopic submucosal dissection for laterally spreading tumors of the colorectum. Endoscopy. 2010 Sep;42(9):714-722.



 15. Matsuoka Y, et. al. Integrated MR-laparoscopy system with respiratory synchronization for minimally invasive liver surgery. J HepatobiliaryPancreat Sci. 2010 Sep;17(5):622-8.
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 20. Toyonaga T, et. al. The performance of a novel ball-tipped Flush knife for endoscopic submucosal dissection: a case-control study. Aliment PharmacolTher. 2010 Oct;32(7):908-15.
 21. Mimura T, et. al. Predictors of Malignant IntraductalPapillary Mucinous Neoplasm of the Pancreas. J ClinGastroenterol. 2010 Oct;44(9):e224-9.
 
 22. Cortes MCC, et. al. Diversity of the cagA gene of Helicobacter pylori strains from patients 1 with gastroduodenal diseases in the Philippines. FEMS ImmunolMed Microbiol. 2010 Oct;60(1):90-7 .
 23. Maeda J, et. al. Inhibitory effects of sulfobacinB on DNA polymerase and inflammation. Int J Mol Med. 2010 Nov;26(5):751-8.
 24. Mizuno S, et. al. Prescreening of a High-Risk Group for Gastric Cancer by Serologically Determined Helicobacter pylori Infection and Atrophic Gastritis. Dig Dis Sci. 2010 Nov;55(11):3132-7.
 25. Nishiumi S, et. al. Serum metabolomics as a novel diagnostic approach for pancreatic cancer. Metabolomics. 2010 Nov;6(4):518-28
 26. Yamamoto M, et. al. The inhibitory effects of intravenous administration of rabbit immunoglobulin G on airway inflammation are dependent upon Fcgamma receptor IIb on CD11c dendritic cells in a murine model. Clin ExpImmunol. 2010 Nov;162(2):315-24.
 27. Kuo TT, et. al. Neonatal Fc Receptor: From Immunity to Therapeutics. J Clin Immunol. 2010 Nov;30(6):777-89.
 28. Toyonaga T, et. al. Endoscopic treatment for early stage colorectal tumors: The comparison between EMR with small incision, simplified ESD, and ESD using the standard Flush knife and the ball tipped Flush knife. ActaChir Iugosl. 2010 Nov;57(3):41-46.
 29. Nobutani K, et. al. Helicobacter heilmannii can induce gastric lymphoid follicles in mice via a Peyer'spatch-independent pathway. FEMS ImmunolMed Microbiol. 2010 Nov;60(2):156-164.


 30. Kawano Y, et. al. Activation of Aryl Hydrocarbon Receptor Induces Hepatic Steatosisvia Upregulationof Fatty Acid Transport. Arch BiochemBiophys. 2010 Dec 15;504(2):221-7.


 31. Tamura I, et. al. Low-dose aspirin-induced gastroduodenalmucosal injury in Japanese patients with arteriosclerotic disease. Intern Med. 2010 Dec 49;(23):2537-45.
 32. Nishiumi S, et. al. Green and black tea suppress hyperglycemia and insulin resistance by retaining the expression of glucose transporter 4 in muscle of high-fat diet-fed C57BL/6J mice. J Agric Food Chem. J Agric Food Chem. 2010 Dec 22;58(24):12916-23
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